Andrew V Kossenkov

Andrew V Kossenkov

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Andrew V Kossenkov

Andrew V Kossenkov

Publications by authors named "Andrew V Kossenkov"

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95Publications

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Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits.

Oncogene 2019 Aug 12. Epub 2019 Aug 12.

Prostate Cancer Discovery and Development Program, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41388-019-0939-7DOI Listing
August 2019

Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology.

Cancer Res 2019 Jul 10. Epub 2019 Jul 10.

Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-1167DOI Listing
July 2019

The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.

Carcinogenesis 2019 May 8. Epub 2019 May 8.

Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA.

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http://dx.doi.org/10.1093/carcin/bgz087DOI Listing
May 2019

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer.

Matrix Biol 2018 09 9;70:20-35. Epub 2018 Mar 9.

Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081240PMC
September 2018

RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism.

PLoS Pathog 2018 01 19;14(1):e1006844. Epub 2018 Jan 19.

Nebraska Center for Virology and the School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792027PMC
January 2018

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy.

Oncotarget 2017 Dec 11;8(68):112184-112198. Epub 2017 Dec 11.

Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA, USA.

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http://dx.doi.org/10.18632/oncotarget.23097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762502PMC
December 2017

TIGIT and Helios Are Highly Expressed on CD4 T Cells in Sézary Syndrome Patients.

J Invest Dermatol 2017 01 1;137(1):257-260. Epub 2016 Sep 1.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.jid.2016.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358509PMC
January 2017

Baseline Immunoglobulin E Levels as a Marker of Doxorubicin- and Trastuzumab-Associated Cardiac Dysfunction.

Circ Res 2016 Oct 31;119(10):1135-1144. Epub 2016 Aug 31.

From the Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA (L.A.B., A.V.K., Q.L., D.W.S.); Department of Pathology and Laboratory Medicine (E.L.P.), Division of Hematology and Oncology (S.D.), Abramson Cancer Center (S.D., B.K.), and Division of Cardiovascular Medicine (B.K.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085891PMC
http://dx.doi.org/10.1161/CIRCRESAHA.116.309004DOI Listing
October 2016

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.

Cancer Cell 2016 08;30(2):257-272

Prostate Cancer Discovery and Development Program, Tumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131882PMC
August 2016

Unlinking an lncRNA from Its Associated cis Element.

Mol Cell 2016 Apr 31;62(1):104-10. Epub 2016 Mar 31.

Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.02.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877494PMC
April 2016

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis.

Nat Commun 2016 Feb 12;7:10715. Epub 2016 Feb 12.

Department of Tumor Microenvironment and Metastasis, The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms10715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754346PMC
February 2016

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.

Proc Natl Acad Sci U S A 2015 Jul 29;112(28):8638-43. Epub 2015 Jun 29.

Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1500722112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507184PMC
July 2015

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

J Natl Cancer Inst 2015 Mar 3;107(3). Epub 2015 Feb 3.

Prostate Cancer Discovery and Development Program (JCG, MT, YCC, SL, MCC, JHS, LRL, DCA), Tumor Microenvironment and Metastasis Program (JCG, MT, YCC, SL, MCC, JHS, DCA), Center for Systems and Computational Biology (AVK), and Center for Chemical Biology and Translational Medicine (DCS), The Wistar Institute, Philadelphia, PA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY (MDS); Istituto Nazionale Genetica Molecolare "Romeo and Enrica Invernizzi," Milan, Italy (VV); Division of Pathology (VV, AF, SB), Division of Neurosurgery (PR), and Division of Surgery (MG), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Metabolon, Inc. Durham, NC (RDM); Department of Pathophysiology and Organ Transplant, University of Milan, Milan, Italy (SB); Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (LRL).

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http://dx.doi.org/10.1093/jnci/dju502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565533PMC
March 2015

ID1 promotes breast cancer metastasis by S100A9 regulation.

Mol Cancer Res 2014 Sep 19;12(9):1334-43. Epub 2014 Jun 19.

The Wistar Institute, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163515PMC
September 2014

Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark.

Nucleic Acids Res 2014 Jun 26;42(11):7028-38. Epub 2014 May 26.

Fox Chase Cancer Center, Philadelphia, PA, 19111 USA

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http://dx.doi.org/10.1093/nar/gku415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066802PMC
June 2014

O-linked β-N-acetylglucosamine (O-GlcNAc) site thr-87 regulates synapsin I localization to synapses and size of the reserve pool of synaptic vesicles.

J Biol Chem 2014 Feb 26;289(6):3602-12. Epub 2013 Nov 26.

From the Department of Biochemistry, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102.

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http://dx.doi.org/10.1074/jbc.M113.512814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916560PMC
February 2014

The peripheral immune response and lung cancer prognosis.

Oncoimmunology 2012 Nov;1(8):1414-1416

The Wistar Institute; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/onci.21096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518521PMC
November 2012

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.

BMC Med Genomics 2012 Sep 6;5:39. Epub 2012 Sep 6.

Department of Surgery, Division of Endocrine and Oncologic Surgery, Rena Rowan Breast Center, Abramson Cancer Center, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1755-8794-5-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505468PMC
September 2012

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.

Cancer Res 2012 Jul 14;72(13):3251-9. Epub 2012 May 14.

Prostate Cancer Discovery and Development Program, Center for Systems and Computational Biology, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-4035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695608PMC
July 2012

ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma.

Cancer Biol Ther 2010 Sep 30;10(6):555-63. Epub 2010 Sep 30.

Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040944PMC
http://dx.doi.org/10.4161/cbt.10.6.12532DOI Listing
September 2010

Matrix factorisation methods applied in microarray data analysis.

Int J Data Min Bioinform 2010 ;4(1):72-90

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998896PMC
June 2010

Stem cells with neural crest characteristics derived from the bulge region of cultured human hair follicles.

J Invest Dermatol 2010 May 15;130(5):1227-36. Epub 2009 Oct 15.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/jid.2009.322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050599PMC
May 2010

Genetic loci that regulate healing and regeneration in LG/J and SM/J mice.

Mamm Genome 2009 Nov-Dec;20(11-12):720-33. Epub 2009 Sep 16.

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19129, USA>

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http://dx.doi.org/10.1007/s00335-009-9216-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652381PMC
March 2010

Matrix factorization for recovery of biological processes from microarray data.

Methods Enzymol 2009 ;467:59-77

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/S0076-6879(09)67003-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997652PMC
January 2010

Determining transcription factor activity from microarray data using Bayesian Markov chain Monte Carlo sampling.

Stud Health Technol Inform 2007 ;129(Pt 2):1250-4

The Wistar Institute, Philadelphia, PA, USA.

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November 2007

Naïve Bayes for microRNA target predictions--machine learning for microRNA targets.

Bioinformatics 2007 Nov 8;23(22):2987-92. Epub 2007 Oct 8.

The Wistar Institute, Philadelphia, PA 19104, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btm484DOI Listing
November 2007

LS-NMF: a modified non-negative matrix factorization algorithm utilizing uncertainty estimates.

BMC Bioinformatics 2006 Mar 28;7:175. Epub 2006 Mar 28.

Division of Population Science, Fox Chase Cancer Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/1471-2105-7-175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450309PMC
March 2006