Andrew Pape

Andrew Pape

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Andrew Pape

Andrew Pape

Publications by authors named "Andrew Pape"

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Hydantoin based inhibitors of MMP13--discovery of AZD6605.

Bioorg Med Chem Lett 2013 Aug 10;23(16):4705-12. Epub 2013 Jun 10.

Oncology Innovative Medicines, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.05.089DOI Listing
August 2013

Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis.

Bioorg Med Chem Lett 2011 Jun 13;21(11):3301-6. Epub 2011 Apr 13.

Respiratory and Inflammation Research Area, AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK.

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http://dx.doi.org/10.1016/j.bmcl.2011.04.028DOI Listing
June 2011

The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis.

Bioorg Med Chem Lett 2011 Mar 18;21(5):1376-81. Epub 2011 Jan 18.

Respiratory and Inflammation Research Area, AstraZeneca, Alderley Park, Macclesfield, Cheshire, UK.

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http://dx.doi.org/10.1016/j.bmcl.2011.01.036DOI Listing
March 2011

Amine-promoted, organocatalytic aziridination of enones.

Org Lett 2007 Jan;9(2):351-3

Department of Chemistry, Imperial College London, South Kensington, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1021/ol062852vDOI Listing
January 2007

Synthesis of [6,n] cis-fused ring compounds via Cr-mediated dearomatisation-ring-closing metathesis.

Org Biomol Chem 2006 Jan 14;4(2):342-51. Epub 2005 Dec 14.

Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1039/b513261dDOI Listing
January 2006