Andrew P Thomas

Andrew P Thomas

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Andrew P Thomas

Andrew P Thomas

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Intercellular calcium waves integrate hormonal control of glucose output in the intact liver.

J Physiol 2019 Jun 29;597(11):2867-2885. Epub 2019 Apr 29.

Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School Rutgers, The State University of New Jersey, Newark, NJ, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1113/JP277650
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http://dx.doi.org/10.1113/JP277650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647271PMC
June 2019

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.

J Biol Chem 2019 Mar 1;294(13):4738-4758. Epub 2019 Feb 1.

From the Institute of Parasitology and Biomedicine "López-Neyra," Consejo Superior de Investigaciones Científicas (CSIC), Avda del Conocimiento s/n, 18016 Granada, Spain,

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http://dx.doi.org/10.1074/jbc.RA118.005008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442034PMC
March 2019

InsP3 Signaling in Apicomplexan Parasites.

Curr Top Med Chem 2017 ;17(19):2158-2165

Department of Molecular Microbiology, Washington University Sch. Med., Saint Louis, USA

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http://dx.doi.org/10.2174/1568026617666170130121042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490149PMC
August 2017

Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations.

J Biol Chem 2015 Jul 15;290(30):18519-33. Epub 2015 Jun 15.

From the Department of Pharmacology and Physiology, New Jersey Medical School Rutgers, The State University of New Jersey, Newark, New Jersey 07103

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http://dx.doi.org/10.1074/jbc.M115.657767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513112PMC
July 2015

Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations.

Cell Rep 2014 Nov 13;9(4):1209-18. Epub 2014 Nov 13.

Department of Pharmacology and Physiology, New Jersey Medical School, Rutgers, The State University of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469397PMC
November 2014

Calcium-dependent regulation of glucose homeostasis in the liver.

Cell Calcium 2014 Jun 17;55(6):306-16. Epub 2014 Feb 17.

Department of Pharmacology and Physiology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, USA.

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http://dx.doi.org/10.1016/j.ceca.2014.02.007DOI Listing
June 2014

Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.

Sci Signal 2014 Jun 24;7(331):ra59. Epub 2014 Jun 24.

Mathematical Cell Physiology, Max Delbrück Center for Molecular Medicine, Robert Rössle Straße 10, Berlin 13125, Germany. Department of Physics, Humboldt University Berlin, Newtonstraße 15, Berlin 12489, Germany.

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http://dx.doi.org/10.1126/scisignal.2005237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092318PMC
June 2014

Acidocalcisomes of Trypanosoma brucei have an inositol 1,4,5-trisphosphate receptor that is required for growth and infectivity.

Proc Natl Acad Sci U S A 2013 Jan 14;110(5):1887-92. Epub 2013 Jan 14.

Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.

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http://dx.doi.org/10.1073/pnas.1216955110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562765PMC
January 2013

Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice.

Mol Cell Neurosci 2012 Aug 10;51(1-2):22-31. Epub 2012 Jul 10.

Department of Neurological Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA.

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http://dx.doi.org/10.1016/j.mcn.2012.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436994PMC
August 2012

Calcium-dependent physiologic and pathologic stimulus-metabolic response coupling in hepatocytes.

Cell Calcium 2012 Jul 6;52(1):93-102. Epub 2012 May 6.

Department of Pharmacology and Physiology, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, United States.

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http://dx.doi.org/10.1016/j.ceca.2012.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391328PMC
July 2012

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.

Cancer Res 2012 Apr 27;72(8):2045-56. Epub 2012 Feb 27.

AstraZeneca Innovation Center China, Building 7, 898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3034DOI Listing
April 2012

Uterine artery embolization immediately preceding laparoscopic myomectomy.

Int J Gynaecol Obstet 2012 Feb 17;116(2):105-8. Epub 2011 Nov 17.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.ijgo.2011.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034570PMC
February 2012

The role of melatonin in parasite biology.

Mol Biochem Parasitol 2012 Jan 1;181(1):1-6. Epub 2011 Oct 1.

Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.molbiopara.2011.09.010DOI Listing
January 2012

Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels.

J Pharmacol Exp Ther 2011 Nov 27;339(2):329-40. Epub 2011 Jul 27.

Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indiana University-Purdue University Indianapolis, 635 Barnhill Dr., MS360A, Indianapolis, IN 46202, USA.

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http://jpet.aspetjournals.org/content/339/2/329.full.pdf
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.111.18367
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http://dx.doi.org/10.1124/jpet.111.183673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199998PMC
November 2011

Single-cell and subcellular measurement of intracellular Ca²+ concentration.

Methods Mol Biol 2005 ;312:87-117

Physiology Group, Vascular Biology Research Centre, Biomedical Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.1385/1-59259-949-4:087DOI Listing
August 2011

Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells.

J Biol Chem 2011 Feb 13;286(7):5905-12. Epub 2010 Dec 13.

Department of Pharmacology and Physiology, UMDNJ, New Jersey Medical School, Newark, New Jersey 07103, USA.

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http://dx.doi.org/10.1074/jbc.M110.188474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037703PMC
February 2011

A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.

Aging Cell 2010 Apr;9(2):203-19

Department of Pharmacology and Physiology, National Institute of Environmental and Health Sciences, 111 TW Alexander dr, MD F0-02, Durham, NC 27709, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2010.00551.xDOI Listing
April 2010

Uncoupling protein-2 modulates myocardial excitation-contraction coupling.

Circ Res 2010 Mar 7;106(4):730-8. Epub 2010 Jan 7.

Department of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.206631DOI Listing
March 2010

Calcineurin activation by slow calcium release from intracellular stores suppresses protein kinase C regulation of L-type calcium channels in L6 cells.

Cell Calcium 2009 Oct 15;46(4):242-7. Epub 2009 Sep 15.

Department of Pharmacology & Physiology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1016/j.ceca.2009.07.006DOI Listing
October 2009

Calcium-dependent activation of mitochondrial metabolism in mammalian cells.

Methods 2008 Nov 12;46(3):224-32. Epub 2008 Oct 12.

Department of Pharmacology and Physiology, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1016/j.ymeth.2008.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640951PMC
November 2008

Optical methods in calcium signaling.

Authors:
Andrew P Thomas

Methods 2008 Nov;46(3):141-2

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http://dx.doi.org/10.1016/j.ymeth.2008.10.026DOI Listing
November 2008

Calcium signaling in liver.

Cell Calcium 2005 Sep-Oct;38(3-4):329-42

Department of Pharmacology and Physiology, New Jersey Medical School of University of Medicine and Dentistry of New Jersey, Medical Science Building, H609, 185 South Orange Avenue, P.O. Box 1709, Newark, NJ 07103-1709, USA.

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http://dx.doi.org/10.1016/j.ceca.2005.06.009DOI Listing
May 2008

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

Cell Metab 2008 May;7(5):456-65

Department of Molecular Oncogenesis, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA.

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http://dx.doi.org/10.1016/j.cmet.2008.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587347PMC
May 2008

Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.

Am J Physiol Regul Integr Comp Physiol 2008 Mar 19;294(3):R784-92. Epub 2007 Dec 19.

Department of Neurology and Neurosciences, New Jersey Medical School, University of Medicine and Dentistry, Newark, New Jersey, USA.

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http://dx.doi.org/10.1152/ajpregu.00645.2007DOI Listing
March 2008

Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators.

Proc Natl Acad Sci U S A 2008 Feb 19;105(8):2859-64. Epub 2008 Feb 19.

Department of General and Environmental Physiology, University of Bari, 70126 Bari, Italy.

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http://dx.doi.org/10.1073/pnas.0712316105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268550PMC
February 2008

Antimalarial drugs disrupt ion homeostasis in malarial parasites.

Mem Inst Oswaldo Cruz 2007 Jun;102(3):329-34

Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Súo Paulo, Brasil.

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http://dx.doi.org/10.1590/s0074-02762007000300012DOI Listing
June 2007

Regulation of the cardiac L-type calcium channel in L6 cells by arginine-vasopressin.

Biochem J 2006 Dec;400(3):411-9

Department of Pharmacology and Physiology, Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1042/BJ20060742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698596PMC
December 2006

Ryanodine receptors in liver.

J Biol Chem 2006 Nov 13;281(45):34086-95. Epub 2006 Sep 13.

Department of Pharmacology and Physiology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA.

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http://dx.doi.org/10.1074/jbc.M607788200DOI Listing
November 2006

Calcium signaling: double duty for calcium at the mitochondrial uniporter.

Curr Biol 2006 Sep;16(18):R812-5

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences - NIH, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1016/j.cub.2006.08.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890018PMC
September 2006

Plant thorn tenosynovitis.

J Clin Rheumatol 2006 Jun;12(3):137-8

Department of Medicine, New Cross Hospital, Wolverhampton, UK.

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http://dx.doi.org/10.1097/01.rhu.0000221997.57886.a6DOI Listing
June 2006

Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks.

Biophys J 2006 May 24;90(9):3120-33. Epub 2006 Feb 24.

Department of Theoretical Biophysics, Institute of Biology, Humboldt University Berlin, 10115 Berlin, Germany.

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http://dx.doi.org/10.1529/biophysj.105.072249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1432125PMC
May 2006

Calcium oscillations in type-1 astrocytes, the effect of a presenilin 1 (PS1) mutation.

Neurosci Lett 2006 Mar 21;395(2):159-64. Epub 2005 Nov 21.

Department of Pharmacology and Physiology, Medical Sciences Building, University of Medicine, Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103-2714, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400501252
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http://dx.doi.org/10.1016/j.neulet.2005.10.088DOI Listing
March 2006

Single-cell and subcellular measurement of intracellular Ca2+ concentration.

Methods Mol Biol 2006 ;312:87-117

Physiology Group, Vascular Biology Research Centre, Biomedical Sciences Division, King's College London, UK.

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February 2006

Modified technique for arthroscopic Bankart repair using anchor sutures.

Arthroscopy 2004 Jul;20 Suppl 2:121-4

Department of Orthopaedic Surgery, New Cross Hospital, Wolverhampton, UK.

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http://dx.doi.org/10.1016/j.arthro.2004.04.035DOI Listing
July 2004

Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors.

Bioorg Med Chem Lett 2004 May;14(9):2245-8

AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK.

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http://dx.doi.org/10.1016/j.bmcl.2004.02.015DOI Listing
May 2004

Calcium signaling in a low calcium environment: how the intracellular malaria parasite solves the problem.

J Cell Biol 2003 Apr 7;161(1):103-10. Epub 2003 Apr 7.

Department of Physiology, Institute of Biosciences, University of São Paulo, São Paulo 05508-900, Brazil.

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http://dx.doi.org/10.1083/jcb.200212130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172890PMC
April 2003

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.

Biochem J 2003 Jan;369(Pt 2):287-99

Henry Wellcome Laboratories for Integrated Cell Signalling, Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, U.K.

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http://dx.doi.org/10.1042/BJ20021288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223096PMC
January 2003

Intracellular calcium signaling.

J Cell Sci 2002 Oct;115(Pt 19):3715-6

Department of Pharmacology and Physiology, UMDNJ - New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1242/jcs.00078DOI Listing
October 2002

Inducible nitric-oxide synthase attenuates vasopressin-dependent Ca2+ signaling in rat hepatocytes.

J Biol Chem 2002 Sep 3;277(37):33776-82. Epub 2002 Jul 3.

Department of Physiology, University College London, Gower Street, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M201904200DOI Listing
September 2002

Denham total knee arthroplasty: a 10-year follow-up study.

J Arthroplasty 2002 Aug;17(5):550-5

Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK.

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August 2002

Ca2+ marks: miniature calcium signals in single mitochondria driven by ryanodine receptors.

Proc Natl Acad Sci U S A 2002 Feb;99(4):2380-5

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1073/pnas.032423699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122373PMC
February 2002