Andrew M Tager

Andrew M Tager

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Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation.

ACS Sens 2019 Sep 22;4(9):2412-2419. Epub 2019 Aug 22.

The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States.

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http://dx.doi.org/10.1021/acssensors.9b01010DOI Listing
September 2019

The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities.

Am J Med Sci 2019 May;357(5):405-410

National Jewish Health, Denver, Colorado; University of Colorado Anschutz Medical Campus and Consortium for Fibrosis Research & Translation, Denver, Colorado.

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http://dx.doi.org/10.1016/j.amjms.2019.02.014DOI Listing
May 2019

Gadofosveset-enhanced lung magnetic resonance imaging to detect ongoing vascular leak in pulmonary fibrosis.

Eur Respir J 2018 05 17;51(5). Epub 2018 May 17.

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1183/13993003.00171-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516082PMC
May 2018

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.

Sci Transl Med 2017 Dec;9(420)

Fibrosis Research Center and Center for Immunology and Inflammatory Diseases, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aal3765DOI Listing
December 2017

High sensitivity HPLC method for determination of the allysine concentration in tissue by use of a naphthol derivative.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Oct 26;1064:7-13. Epub 2017 Aug 26.

Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2017.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662445PMC
October 2017

Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine-Based Probe.

Angew Chem Int Ed Engl 2017 08 13;56(33):9825-9828. Epub 2017 Jul 13.

A. A. Martinos Center for Biomedical Imaging and the Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 2301, Charlestown, MA, 02129, USA.

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http://dx.doi.org/10.1002/anie.201704773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558833PMC
August 2017

Humanized mouse models of latent HIV infection.

Curr Opin Virol 2017 08 12;25:97-104. Epub 2017 Aug 12.

Human Immune System Mouse Program, Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, USA; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2017.07.027DOI Listing
August 2017

Chemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa.

JCI Insight 2017 04 6;2(7):e88533. Epub 2017 Apr 6.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/jci.insight.88533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374062PMC
April 2017

Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.

Kidney Int 2017 03 4;91(3):628-641. Epub 2016 Dec 4.

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313343PMC
March 2017

The autotaxin-lysophosphatidic acid pathway emerges as a therapeutic target to prevent liver cancer.

Mol Cell Oncol 2017 31;4(3):e1311827. Epub 2017 Mar 31.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1080/23723556.2017.1311827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462520PMC
March 2017

Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells.

Biomaterials 2017 02 25;117:44-53. Epub 2016 Nov 25.

Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA; Dept. of Biological Engineering, MIT, Cambridge, MA, USA; Dept. of Materials Science & Engineering, MIT, Cambridge, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204257PMC
February 2017

Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo.

J Infect Dis 2016 08 29;214(4):612-6. Epub 2016 Jun 29.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1093/infdis/jiw203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957443PMC
August 2016

Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion.

Am J Respir Cell Mol Biol 2016 06;54(6):831-42

1 Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2015-0040OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942213PMC
June 2016

Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.

FASEB J 2016 06 22;30(6):2435-50. Epub 2016 Mar 22.

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA;

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http://dx.doi.org/10.1096/fj.201500197RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871797PMC
June 2016

TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice.

Cell Rep 2016 05 12;15(8):1715-27. Epub 2016 May 12.

Program in Cellular and Molecular Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881429PMC
May 2016

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.

Nanomedicine 2015 Aug 8;11(6):1299-308. Epub 2015 May 8.

Laboratorio InmunoBiología Molecular, Hospital Gregorio Marañón, IISGM, Spanish HIV-HGM Biobank, CIBER-BBN, Madrid, Spain; Plataforma-Laboratorio, Hospital Gregorio Marañón, IISGM, CIBER-BBN, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2015.04.013DOI Listing
August 2015

The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.

Pharmacol Rev 2015 ;67(1):103-17

Pulmonary and Critical Care Unit and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (R.S.K., A.M.T.); and Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois (J.K.L.)

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http://dx.doi.org/10.1124/pr.114.009381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279074PMC
June 2015

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.

Am J Physiol Lung Cell Mol Physiol 2015 Feb 12;308(4):L344-57. Epub 2014 Dec 12.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota;

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http://dx.doi.org/10.1152/ajplung.00300.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329470PMC
February 2015

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.

Cell Stem Cell 2014 Nov 6;15(5):643-52. Epub 2014 Nov 6.

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02142, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269831PMC
November 2014

New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.

Am J Respir Crit Care Med 2014 Oct;190(8):867-78

Pulmonary and Critical Care Unit and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201403-0509PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299574PMC
October 2014

PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads.

PLoS One 2013 21;8(10):e77780. Epub 2013 Oct 21.

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America ; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077780PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804573PMC
September 2014

Fibrosis--a lethal component of systemic sclerosis.

Nat Rev Rheumatol 2014 Jul 22;10(7):390-402. Epub 2014 Apr 22.

The Toronto Western Research Institute, Division of Orthopaedics, Toronto Western Hospital, The University Health Network, 60 Leonard Avenue, Toronto, ON M5T 2S8, Canada.

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http://dx.doi.org/10.1038/nrrheum.2014.53DOI Listing
July 2014

Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis.

BMC Pulm Med 2014 Jan 27;14. Epub 2014 Jan 27.

Pulmonary and Critical Care Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/1471-2466-14-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906883PMC
January 2014

Electron tomography of HIV-1 infection in gut-associated lymphoid tissue.

PLoS Pathog 2014 Jan 30;10(1):e1003899. Epub 2014 Jan 30.

Division of Biology & Biological Engineering 114-96, California Institute of Technology, Pasadena, California, United States of America ; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907528PMC
January 2014

Recent advances in humanized mice: accelerating the development of an HIV vaccine.

J Infect Dis 2013 Nov;208 Suppl 2:S121-4

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School.

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http://dx.doi.org/10.1093/infdis/jit451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807973PMC
November 2013

Humoral immunity in humanized mice: a work in progress.

J Infect Dis 2013 Nov;208 Suppl 2:S155-9

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology.

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http://dx.doi.org/10.1093/infdis/jit448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807975PMC
November 2013

Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis.

Biochim Biophys Acta 2013 Jul 14;1832(7):911-21. Epub 2013 Mar 14.

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.bbadis.2013.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041487PMC
July 2013

LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.

FASEB J 2013 May 15;27(5):1830-46. Epub 2013 Jan 15.

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://www.fasebj.org/doi/10.1096/fj.12-219378
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http://dx.doi.org/10.1096/fj.12-219378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633809PMC
May 2013

Graft versus host disease in the bone marrow, liver and thymus humanized mouse model.

PLoS One 2012 5;7(9):e44664. Epub 2012 Sep 5.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044664PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434179PMC
February 2013

Biomechanical regulation of mesenchymal cell function.

Curr Opin Rheumatol 2013 Jan;25(1):92-100

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115-6021, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056746PMC
http://dx.doi.org/10.1097/BOR.0b013e32835b13cdDOI Listing
January 2013

HIV-infected T cells are migratory vehicles for viral dissemination.

Nature 2012 Oct 1;490(7419):283-7. Epub 2012 Aug 1.

The Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/nature11398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470742PMC
October 2012

Sphingolipid regulation of tissue fibrosis.

Open Rheumatol J 2012 15;6:123-9. Epub 2012 Jun 15.

Pulmonary and Critical Care Unit, and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://benthamopen.com/ABSTRACT/TORJ-6-123
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http://dx.doi.org/10.2174/1874312901206010123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395890PMC
August 2012

Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.

Proc Am Thorac Soc 2012 Jul;9(3):102-10

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1513/pats.201201-005AWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455616PMC
July 2012

The monocyte in atherosclerosis--should I stay or should I go now?

N Engl J Med 2012 May;366(18):1734-6

Massachusetts General Hospital and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcibr1200164DOI Listing
May 2012

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury.

Am J Respir Cell Mol Biol 2012 Mar 20;46(3):355-64. Epub 2011 Oct 20.

Pulmonary and Critical Care Unit, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, 149 13th Street, Room 8301, Charlestown, MA 02129, USA.

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http://www.scripps.edu/chun/Funke%20AJRCMB%202012.pdf
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http://dx.doi.org/10.1165/rcmb.2010-0155OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326436PMC
March 2012

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.

J Clin Invest 2011 Jun 16;121(6):2401-12. Epub 2011 May 16.

Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI45876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104760PMC
June 2011

Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.

Am J Respir Cell Mol Biol 2010 Dec 15;43(6):662-73. Epub 2010 Jan 15.

Pulmonary and Critical Care Unit, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1165/rcmb.2009-0345OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993087PMC
December 2010

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.

J Cell Biol 2010 Aug;190(4):693-706

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115.

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http://dx.doi.org/10.1083/jcb.201004082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928007PMC
August 2010

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4.

J Clin Invest 2010 Jun 17;120(6):2049-57. Epub 2010 May 17.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1172/JCI38644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877927PMC
June 2010

Case records of the Massachusetts General Hospital. Case 32-2009. A 27-year-old man with progressive dyspnea.

N Engl J Med 2009 Oct;361(16):1585-93

Pulmonary and Critical Care Unit and the Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, USA.

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http://dx.doi.org/10.1056/NEJMcpc0905544DOI Listing
October 2009

Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.

J Allergy Clin Immunol 2009 Jan 4;123(1):67-73.e3. Epub 2008 Dec 4.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jaci.2008.09.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782398PMC
January 2009

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria.

Proc Natl Acad Sci U S A 2008 Mar 17;105(12):4814-9. Epub 2008 Mar 17.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1073/pnas.0801544105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290783PMC
March 2008

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.

Nat Med 2008 Jan 9;14(1):45-54. Epub 2007 Dec 9.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, CNY149-8301, 149 13th Street, Charlestown, Massachusetts 02129 USA.

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http://dx.doi.org/10.1038/nm1685DOI Listing
January 2008

Inhibited aortic aneurysm formation in BLT1-deficient mice.

J Immunol 2007 Jul;179(1):691-7

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.4049/jimmunol.179.1.691DOI Listing
July 2007

Chitin induces accumulation in tissue of innate immune cells associated with allergy.

Nature 2007 May 22;447(7140):92-6. Epub 2007 Apr 22.

Howard Hughes Medical Institute, Departments of Medicine and Microbiology/Immunology, University of California San Francisco, San Francisco, California 94143-0795, USA.

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http://www.nature.com/articles/nature05746
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http://dx.doi.org/10.1038/nature05746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527589PMC
May 2007

Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells.

Circulation 2006 May 8;113(19):2301-12. Epub 2006 May 8.

Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.605121DOI Listing
May 2006

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

J Exp Med 2006 Apr 27;203(4):829-35. Epub 2006 Mar 27.

Division of Rheumatology, Allergy, and Immunology, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1084/jem.20052349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118298PMC
April 2006

STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells.

J Immunol 2006 Apr;176(8):4959-67

Division of Rheumatology, Allergy and Immunology, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://www.jimmunol.org/content/176/8/4959.full.pdf
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http://dx.doi.org/10.4049/jimmunol.176.8.4959DOI Listing
April 2006

Antibody-antigen interaction in the airway drives early granulocyte recruitment through BLT1.

Am J Physiol Lung Cell Mol Physiol 2006 Jan 26;290(1):L170-8. Epub 2005 Aug 26.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00212.2005
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http://dx.doi.org/10.1152/ajplung.00212.2005DOI Listing
January 2006

The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans.

Blood 2006 Jan 22;107(2):444-53. Epub 2005 Sep 22.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2005-06-23
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http://dx.doi.org/10.1182/blood-2005-06-2362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1490027PMC
January 2006

BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation.

J Exp Med 2005 Jul;202(1):97-110

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1084/jem.20042481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212891PMC
July 2005

Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10.

Am J Respir Cell Mol Biol 2004 Oct 17;31(4):395-404. Epub 2004 Jun 17.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Building 149-8301, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1165/rcmb.2004-0175OCDOI Listing
October 2004

T-cell trafficking in asthma: lipid mediators grease the way.

Nat Rev Immunol 2004 Sep;4(9):711-24

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Building 149-8301, 13th Street, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/nri1438DOI Listing
September 2004

BLT1 and BLT2: the leukotriene B(4) receptors.

Prostaglandins Leukot Essent Fatty Acids 2003 Aug-Sep;69(2-3):123-34

Division of Rheumatology, Allergy and Immunology, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Building 149-8301, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0952-3278(03)00073-5DOI Listing
April 2004

Mechanisms of leukotriene B4--triggered monocyte adhesion.

Arterioscler Thromb Vasc Biol 2003 Oct 28;23(10):1761-7. Epub 2003 Aug 28.

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown 02129, USA.

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http://dx.doi.org/10.1161/01.ATV.0000092941.77774.3CDOI Listing
October 2003

Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment.

Nat Immunol 2003 Oct 31;4(10):982-90. Epub 2003 Aug 31.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://www.nature.com/articles/ni970
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http://dx.doi.org/10.1038/ni970DOI Listing
October 2003

Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues.

Nat Immunol 2003 Oct 31;4(10):965-73. Epub 2003 Aug 31.

Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/ni972
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http://dx.doi.org/10.1038/ni972DOI Listing
October 2003

IFN-gamma-inducible protein 10 (CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma.

J Immunol 2002 May;168(10):5278-86

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.4049/jimmunol.168.10.5278DOI Listing
May 2002

Clinical problem-solving. More than your average wheeze.

N Engl J Med 2002 Feb;346(6):438-42

Department of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1056/NEJMcps012402DOI Listing
February 2002