Publications by authors named "Andrew M Intlekofer"

37Publications

Oncogenic Mechanisms and Therapeutic Targeting of Metabolism in Leukemia and Lymphoma.

Cold Spring Harb Perspect Med 2020 Aug 17. Epub 2020 Aug 17.

Department of Medicine and Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1101/cshperspect.a035477DOI Listing
August 2020

The epigenomics of sarcoma.

Nat Rev Cancer 2020 Aug 11. Epub 2020 Aug 11.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/s41568-020-0288-4DOI Listing
August 2020

Metabolic signatures of cancer cells and stem cells.

Nat Metab 2019 Feb 11;1(2):177-188. Epub 2019 Feb 11.

Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065 USA.

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http://dx.doi.org/10.1038/s42255-019-0032-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594714PMC
February 2019

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.

Cell Metab 2018 02 11;27(2):428-438.e5. Epub 2018 Jan 11.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803449PMC
February 2018

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.

Nat Chem Biol 2017 05 6;13(5):494-500. Epub 2017 Mar 6.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nchembio.2307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516644PMC
May 2017

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Hypoxia Induces Production of L-2-Hydroxyglutarate.

Cell Metab 2015 Aug 23;22(2):304-11. Epub 2015 Jul 23.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527873PMC
August 2015

Treatment response of cutaneous mantle cell lymphoma to ibrutinib and radiotherapy.

Clin Lymphoma Myeloma Leuk 2015 Jun 18;15(6):e113-5. Epub 2014 Nov 18.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Dermatology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2014.11.003DOI Listing
June 2015

Precision therapy for lymphoma--current state and future directions.

Nat Rev Clin Oncol 2014 Oct 19;11(10):585-96. Epub 2014 Aug 19.

Lymphoma Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 330, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.137DOI Listing
October 2014

From empiric to mechanism-based therapy for peripheral T cell lymphoma.

Int J Hematol 2014 Mar 8;99(3):249-62. Epub 2014 Feb 8.

Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 330, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s12185-014-1521-2DOI Listing
March 2014

At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy.

J Leukoc Biol 2013 Jul 26;94(1):25-39. Epub 2013 Apr 26.

Department of Medicine, Cancer Biology and Genetics Program, and Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1189/jlb.1212621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685017PMC
July 2013

Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

J Immunol 2010 Dec 12;185(12):7151-5. Epub 2010 Nov 12.

Abramson Family Cancer Research Institute, Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1003193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997140PMC
December 2010

Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.

J Immunol 2010 Nov 8;185(9):4988-92. Epub 2010 Oct 8.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1002042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975552PMC
November 2010

A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

Immunity 2009 Aug 6;31(2):309-20. Epub 2009 Aug 6.

Immunology Program and Wistar Vaccine Center, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.immuni.2009.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747257PMC
August 2009

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

Genes Dev 2009 Jul;23(14):1665-76

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://genesdev.cshlp.org/content/23/14/1665.full.pdf
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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.1793709
Publisher Site
http://dx.doi.org/10.1101/gad.1793709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714710PMC
July 2009

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

J Exp Med 2007 Sep 13;204(9):2015-21. Epub 2007 Aug 13.

Abramson Family Cancer Research Institute, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20070841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118697PMC
September 2007

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Science 2007 Mar 1;315(5819):1687-91. Epub 2007 Mar 1.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1139393DOI Listing
March 2007

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells.

J Immunol 2007 Mar;178(5):2730-6

Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.4049/jimmunol.178.5.2730DOI Listing
March 2007

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.

J Exp Med 2007 Feb 12;204(2):267-72. Epub 2007 Feb 12.

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20061982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118724PMC
February 2007

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.

J Immunol 2006 Dec;177(11):7515-9

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://www.jimmunol.org/content/177/11/7515.full.pdf
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http://dx.doi.org/10.4049/jimmunol.177.11.7515DOI Listing
December 2006

Not-so-great expectations: re-assessing the essence of T-cell memory.

Immunol Rev 2006 Jun;211:203-13

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2006.00396.xDOI Listing
June 2006

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.

Nat Immunol 2005 Dec 6;6(12):1236-44. Epub 2005 Nov 6.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni1268DOI Listing
December 2005