Andrew M Intlekofer

Andrew M Intlekofer

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Andrew M Intlekofer

Andrew M Intlekofer

Publications by authors named "Andrew M Intlekofer"

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33Publications

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Metabolic signatures of cancer cells and stem cells.

Nat Metab 2019 Feb 11;1(2):177-188. Epub 2019 Feb 11.

Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065 USA.

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http://dx.doi.org/10.1038/s42255-019-0032-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594714PMC
February 2019

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.

Cell Metab 2018 02 11;27(2):428-438.e5. Epub 2018 Jan 11.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803449PMC
February 2018

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.

Nat Chem Biol 2017 05 6;13(5):494-500. Epub 2017 Mar 6.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nchembio.2307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516644PMC
May 2017

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Hypoxia Induces Production of L-2-Hydroxyglutarate.

Cell Metab 2015 Aug 23;22(2):304-11. Epub 2015 Jul 23.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527873PMC
August 2015

Treatment response of cutaneous mantle cell lymphoma to ibrutinib and radiotherapy.

Clin Lymphoma Myeloma Leuk 2015 Jun 18;15(6):e113-5. Epub 2014 Nov 18.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Dermatology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2014.11.003DOI Listing
June 2015

Precision therapy for lymphoma--current state and future directions.

Nat Rev Clin Oncol 2014 Oct 19;11(10):585-96. Epub 2014 Aug 19.

Lymphoma Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 330, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.137DOI Listing
October 2014

From empiric to mechanism-based therapy for peripheral T cell lymphoma.

Int J Hematol 2014 Mar 8;99(3):249-62. Epub 2014 Feb 8.

Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 330, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s12185-014-1521-2DOI Listing
March 2014

At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy.

J Leukoc Biol 2013 Jul 26;94(1):25-39. Epub 2013 Apr 26.

Department of Medicine, Cancer Biology and Genetics Program, and Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1189/jlb.1212621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685017PMC
July 2013

Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

J Immunol 2010 Dec 12;185(12):7151-5. Epub 2010 Nov 12.

Abramson Family Cancer Research Institute, Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1003193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997140PMC
December 2010

Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.

J Immunol 2010 Nov 8;185(9):4988-92. Epub 2010 Oct 8.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1002042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975552PMC
November 2010

A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

Immunity 2009 Aug 6;31(2):309-20. Epub 2009 Aug 6.

Immunology Program and Wistar Vaccine Center, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.immuni.2009.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747257PMC
August 2009

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

Genes Dev 2009 Jul;23(14):1665-76

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://genesdev.cshlp.org/content/23/14/1665.full.pdf
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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.1793709
Publisher Site
http://dx.doi.org/10.1101/gad.1793709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714710PMC
July 2009

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

J Exp Med 2007 Sep 13;204(9):2015-21. Epub 2007 Aug 13.

Abramson Family Cancer Research Institute, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20070841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118697PMC
September 2007

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells.

J Immunol 2007 Mar;178(5):2730-6

Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.4049/jimmunol.178.5.2730DOI Listing
March 2007

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Science 2007 Mar 1;315(5819):1687-91. Epub 2007 Mar 1.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1139393DOI Listing
March 2007

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.

J Exp Med 2007 Feb 12;204(2):267-72. Epub 2007 Feb 12.

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20061982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118724PMC
February 2007

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.

J Immunol 2006 Dec;177(11):7515-9

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://www.jimmunol.org/content/177/11/7515.full.pdf
Web Search
http://dx.doi.org/10.4049/jimmunol.177.11.7515DOI Listing
December 2006

Not-so-great expectations: re-assessing the essence of T-cell memory.

Immunol Rev 2006 Jun;211:203-13

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2006.00396.xDOI Listing
June 2006

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.

Nat Immunol 2005 Dec 6;6(12):1236-44. Epub 2005 Nov 6.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni1268DOI Listing
December 2005