Dr Andrew M Harrison, MD, PhD - Mayo Clinic - Postdoctoral researcher

Dr Andrew M Harrison

MD, PhD

Mayo Clinic

Postdoctoral researcher

Rochester, MN | United States

Main Specialties: Pulmonary Disease & Critical Care Medicine

Additional Specialties: Clinical Informatics

ORCID logohttps://orcid.org/0000-0003-0063-9421

Dr Andrew M Harrison, MD, PhD - Mayo Clinic - Postdoctoral researcher

Dr Andrew M Harrison

MD, PhD
Introduction

Clinical Informatics, Critical Care, Health Services Research
BS, Physics & Genetics, Rutgers University, 2010
MD-PhD, Mayo Clinic College of Medicine and Science, 2018
- Medical Scientist Training Program (MSTP)
-- Mayo Clinic School of Medicine
-- Mayo Clinic Graduate School of Biomedical Sciences
--- Biomedical Sciences, Clinical and Translational Science track

Primary Affiliation: Mayo Clinic - Rochester, MN , United States

Specialties:

Additional Specialties:

Research Interests:


View Dr Andrew M Harrison’s Resume / CV
Metrics

47

Publications

912

Profile Views

376

Reads

106

PubMed Central Citations

Education
Feb 2018
Mayo Clinic College of Medicine and Science
MD-PhD
May 2010
Rutgers University
BS
Experience
Sep 2013
Development, testing, and refining the failure to rescue sepsis sniffer
PI

Publications

47Publications

376Reads

106PubMed Central Citations

Implementation of a New Guideline and Educational Sessions to Reduce Low-Value Continuous Pulse Oximetry Among Hospitalized Patients.

South Med J 2018 02;111(2):87-92

From the Departments of Internal Medicine, Medical Scientist Training Program, and Nursing Administration, Mayo Clinic, Jacksonville, Florida.

View Article
February 2018
13 Reads
1.12 Impact Factor

Transapical versus transfemoral approach and risk of acute kidney injury following transcatheter aortic valve replacement: a propensity-adjusted analysis.

Ren Fail 2017 Nov 21;39(1):13-18. Epub 2016 Oct 21.

a Department of Internal Medicine, Division of Nephrology and Hypertension , Mayo Clinic , Rochester , MN , USA.

View Article
November 2017
14 Reads
2 PubMed Central Citations(source)
0.78 Impact Factor

Persistent acute kidney injury following transcatheter aortic valve replacement.

J Card Surg 2017 Sep 22;32(9):550-555. Epub 2017 Aug 22.

Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

View Article
September 2017
15 Reads
0.89 Impact Factor

Medical Students Call for Single-Payer National Health Insurance.

Acad Med 2017 Jun;92(6):735

Year 7 student, Medical Scientist Training Program, Mayo Clinic, Rochester, Minnesota;

View Article
June 2017
13 Reads
2.93 Impact Factor

Prognostic Importance of Low Admission Serum Creatinine Concentration for Mortality in Hospitalized Patients.

Am J Med 2017 May 18;130(5):545-554.e1. Epub 2016 Dec 18.

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minn; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minn. Electronic address:

View Article
May 2017
12 Reads
5.00 Impact Factor

Comparison of methods of alert acknowledgement by critical care clinicians in the ICU setting.

PeerJ 2017 14;5:e3083. Epub 2017 Mar 14.

Department of Anesthesiology, Mayo Clinic , Rochester , MN , United States of America.

View Article
March 2017
12 Reads
1 PubMed Central Citation(source)

Testing modes of computerized sepsis alert notification delivery systems.

BMC Med Inform Decis Mak 2016 12 9;16(1):156. Epub 2016 Dec 9.

Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

View Article
December 2016
16 Reads
1 PubMed Central Citation(source)
1.50 Impact Factor

Necessary but not sufficient: unique author identifiers.

BMJ Innov 2016 Oct 23;2(4):141-143. Epub 2016 Sep 23.

Health Psychology Section, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

View Article
October 2016
13 Reads

Systematic Review of the Use of Phytochemicals for Management of Pain in Cancer Therapy.

Biomed Res Int 2015 20;2015:506327. Epub 2015 Oct 20.

Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA.

View Article
August 2016
18 Reads
2 PubMed Central Citations(source)

Development and Implementation of Sepsis Alert Systems.

Clin Chest Med 2016 06 20;37(2):219-29. Epub 2016 Feb 20.

Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address:

View Article
June 2016
15 Reads
4 PubMed Central Citations(source)
2.07 Impact Factor

AKI after Transcatheter or Surgical Aortic Valve Replacement.

J Am Soc Nephrol 2016 06 20;27(6):1854-60. Epub 2015 Oct 20.

Division of Nephrology and Hypertension, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine,

View Article
June 2016
13 Reads
11 PubMed Central Citations(source)
9.34 Impact Factor

Temporal trends in the utilization of vasopressors in intensive care units: an epidemiologic study.

BMC Pharmacol Toxicol 2016 05 7;17(1):19. Epub 2016 May 7.

Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

View Article
May 2016
14 Reads
2 PubMed Central Citations(source)

The Effect of an Electronic Checklist on Critical Care Provider Workload, Errors, and Performance.

J Intensive Care Med 2016 Mar 12;31(3):205-12. Epub 2014 Nov 12.

Multidisciplinary Epidemiology and Translational Research in Intensive Care (METRIC), Mayo Clinic, Rochester, MN, USA Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA

View Article
March 2016
12 Reads
4 PubMed Central Citations(source)

Admission hyperuricemia increases the risk of acute kidney injury in hospitalized patients(.).

Clin Kidney J 2016 Feb 9;9(1):51-6. Epub 2015 Sep 9.

Division of Nephrology and Hypertension, Department of Medicine , Mayo Clinic , Rochester, MA , USA.

View Article
February 2016
18 Reads
7 PubMed Central Citations(source)

The comparison of the commonly used surrogates for baseline renal function in acute kidney injury diagnosis and staging.

BMC Nephrol 2016 Jan 9;17. Epub 2016 Jan 9.

Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

View Article
January 2016
10 Reads
2 PubMed Central Citations(source)
1.52 Impact Factor

Sodium Correction Practice and Clinical Outcomes in Profound Hyponatremia.

Mayo Clin Proc 2015 Oct;90(10):1348-55

Multidisciplinary Epidemiology and Translational Research in Intensive Care, Mayo Clinic, Rochester, MN; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.

View Article
October 2015
24 Reads
3 PubMed Central Citations(source)
6.26 Impact Factor

Automated Sepsis Detection, Alert, and Clinical Decision Support: Act on It or Silence the Alarm?

Crit Care Med 2015 Aug;43(8):1776-7

Medical Scientist Training Program, Mayo Graduate School, Mayo Clinic, Rochester, MN Department of Anesthesiology, Mayo Clinic, Rochester, MN Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.

View Article
August 2015
17 Reads
2 PubMed Central Citations(source)
6.31 Impact Factor

Improving the Accuracy of Cardiovascular Component of the Sequential Organ Failure Assessment Score.

Crit Care Med 2015 Jul;43(7):1449-57

1Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN. 2Department of Anesthesiology, Multidisciplinary Epidemiology and Translational Research in Intensive Care (METRIC), Mayo Clinic, Rochester, MN. 3Mayo School of Graduate Medical Education, Medical Scientist Training Program, Mayo Clinic, Rochester, MN. 4Department of Anesthesiology, Mayo Clinic, Rochester, MN.

View Article
July 2015
13 Reads
2 PubMed Central Citations(source)
6.31 Impact Factor

Agreement between whole blood and plasma sodium measurements in profound hyponatremia.

Clin Biochem 2015 May 13;48(7-8):525-8. Epub 2015 Mar 13.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

View Article
May 2015
18 Reads
2.23 Impact Factor

Developing the surveillance algorithm for detection of failure to recognize and treat severe sepsis.

Mayo Clin Proc 2015 Feb 6;90(2):166-75. Epub 2015 Jan 6.

Multidisciplinary Epidemiology and Translational Research in Intensive Care, Mayo Clinic, Rochester MN; Department of Anesthesiology, Mayo Clinic, Rochester MN. Electronic address:

View Article
February 2015
12 Reads
10 PubMed Central Citations(source)
6.26 Impact Factor

Rituximab for non-Hodgkin's lymphoma: a story of rapid success in translation.

Clin Transl Sci 2014 Feb 3;7(1):82-6. Epub 2013 Oct 3.

Medical Scientist Training Program, Mayo Clinic, Rochester, Minnesota, USA.

View Article
February 2014
14 Reads
5 PubMed Central Citations(source)
2.11 Impact Factor

Validation of computerized automatic calculation of the sequential organ failure assessment score.

Crit Care Res Pract 2013 9;2013:975672. Epub 2013 Jul 9.

Medical Scientist Training Program, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA ; Multidisciplinary Epidemiology and Translational Research in Intensive Care (METRIC), Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.

View Article
August 2013
13 Reads
3 PubMed Central Citations(source)

Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.

J Cell Biol 2012 Dec 3;199(6):931-49. Epub 2012 Dec 3.

Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.

View Article
December 2012
15 Reads
33 PubMed Central Citations(source)
9.83 Impact Factor

Microtubule-depolymerizing kinesin KLP10A restricts the length of the acentrosomal meiotic spindle in Drosophila females.

Genetics 2012 Oct 3;192(2):431-40. Epub 2012 Aug 3.

Waksman Institute, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.

View Article
October 2012
26 Reads
11 PubMed Central Citations(source)

Lessons learned from an unusual case of inflammatory breast cancer.

J Surg Educ 2012 May-Jun;69(3):350-4

Mayo Medical School, Mayo Clinic, Rochester, Minnesota 55905, USA.

View Article
August 2012
16 Reads
1 PubMed Central Citation(source)

Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer.

Oncogene. 2011 Aug 30(34):3705-15.

Oncogene

Glycogen synthase kinase-3 beta (GSK-3β) is overexpressed in a number of human malignancies and has been shown to contribute to tumor cell proliferation and survival. Although regulation of GSK-3β activity has been extensively studied, the mechanisms governing GSK-3β gene expression are still unknown. Using pancreatic cancer as a model, we find that constitutively active Ras signaling increases GSK-3β gene expression via the canonical mitogen-activated protein kinase signaling pathway. Analysis of the mechanism revealed that K-Ras regulates the expression of this kinase through two highly conserved E-twenty six (ETS) binding elements within the proximal region. Furthermore, we demonstrate that mutant K-Ras enhances ETS2 loading onto the promoter, and ETS requires its transcriptional activity to increase GSK-3β gene transcription in pancreatic cancer cells. Lastly, we show that ETS2 cooperates with p300 histone acetyltransferase to remodel chromatin and promote GSK-3β expression. Taken together, these results provide a general mechanism for increased expression of GSK-3β in pancreatic cancer and perhaps other cancers, where Ras signaling is deregulated.

View Article
August 2011
19 Reads