Andrew L Kung

Andrew L Kung

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Andrew L Kung

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BET bromodomain proteins regulate enhancer function during adipogenesis.

Proc Natl Acad Sci U S A 2018 02 14;115(9):2144-2149. Epub 2018 Feb 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1711155115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834672PMC
February 2018

Germline mutations detected in pediatric sequencing studies impact parents' evaluation and care.

Cold Spring Harb Mol Case Stud 2017 Nov 21;3(6). Epub 2017 Nov 21.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1101/mcs.a001925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701310PMC
November 2017

HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.

Oncotarget 2017 Oct 5;8(46):80109-80123. Epub 2017 Jul 5.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.18632/oncotarget.19019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655183PMC
October 2017

Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover's Distance.

Sci Rep 2017 08 1;7(1):7035. Epub 2017 Aug 1.

Stony Brook University, Departments of Computer Science and Applied Mathematics & Statistics, Stony Brook, 11794, USA.

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http://dx.doi.org/10.1038/s41598-017-07551-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539155PMC
August 2017

Image-guided transplantation of single cells in the bone marrow of live animals.

Sci Rep 2017 06 20;7(1):3875. Epub 2017 Jun 20.

Advanced Microscopy Program, Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-02896-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478633PMC
June 2017

A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma.

Cold Spring Harb Mol Case Stud 2017 03;3(2):a001396

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1101/mcs.a001396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334470PMC
March 2017

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

Targeting MTHFD2 in acute myeloid leukemia.

J Exp Med 2016 06 20;213(7):1285-306. Epub 2016 Jun 20.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142

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http://dx.doi.org/10.1084/jem.20151574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925018PMC
June 2016

Inhibition of inflammatory arthritis using fullerene nanomaterials.

PLoS One 2015 16;10(4):e0126290. Epub 2015 Apr 16.

University of North Carolina Greensboro, Joint School of Nanosceince and Nanoengineering, Greensboro, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126290PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400016PMC
April 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth.

Hypoxia (Auckl) 2016;4:15-27. Epub 2016 Mar 4.

Ludwig Institute for Cancer Research Ltd, Stockholm, Sweden; Department of Microbiology and Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2147/HP.S96366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981084PMC
March 2016

Characterization of a novel fusion gene EML4-NTRK3 in a case of recurrent congenital fibrosarcoma.

Cold Spring Harb Mol Case Stud 2015 Oct;1(1):a000471

Columbia University Medical Center, Department of Pediatric Oncology/Hematology/Stem Cell Transplantation, Department of Pediatrics, New York, New York 10032, USA;

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http://dx.doi.org/10.1101/mcs.a000471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850889PMC
October 2015

Overcoming challenges to meaningful informed consent for whole genome sequencing in pediatric cancer research.

Pediatr Blood Cancer 2015 Aug 1;62(8):1374-80. Epub 2015 Apr 1.

Department of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation, Columbia University Medical Center, 161 Fort Washington Avenue, IP7, New York, New York.

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http://dx.doi.org/10.1002/pbc.25520DOI Listing
August 2015

Allogeneic Hematopoietic Cell Transplantation for Children with Sickle Cell Disease Is Beneficial and Cost-Effective: A Single-Center Analysis.

Biol Blood Marrow Transplant 2015 Jul 20;21(7):1258-65. Epub 2015 Jan 20.

Department of Pediatrics, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.bbmt.2015.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605133PMC
July 2015

In vivo imaging of endogenous enzyme activities using luminescent 1,2-dioxetane compounds.

J Biomed Sci 2015 Jun 24;22:45. Epub 2015 Jun 24.

Columbia University Medical Center, 3959 Broadway, New York, NY, 10032, USA.

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http://dx.doi.org/10.1186/s12929-015-0155-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477311PMC
June 2015

Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma.

Neuro Oncol 2015 May 2;17(5):697-707. Epub 2014 Nov 2.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (A.L.G., J.A.P., J.H.-R.H., B.H.-E.); Division of Hematology-Oncology, Boston Children's Hospital, Boston, Massachusetts (A.L.G.); Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.H.R., L.A.R., C.L.M., D.S.K., K.L.L.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.H.R., K.L.L.); Karyopharm Therapeutics, Natick, Massachusetts (D.M., S.S.); Lurie Family Imaging Center, Dana-Farber Cancer Institute, Boston, Massachusetts (K.J.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.); Department of Pediatrics, Columbia University Medical Center, New York, New York (A.L.K.).

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http://dx.doi.org/10.1093/neuonc/nou303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482855PMC
May 2015

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.

Clin Cancer Res 2015 May 16;21(10):2348-58. Epub 2015 Feb 16.

Division of Hematology/Oncology, Department of Pediatric Oncology, Boston Children's Hospital, Dana-Farber-Cancer Institute, and Harvard Medical School, Boston, Massachusetts. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Harvard Stem Cell Institute, Boston, Massachusetts.

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http://clincancerres.aacrjournals.org/content/early/2015/02/
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http://clincancerres.aacrjournals.org/content/early/2015/04/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-1290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433811PMC
May 2015

Examining the utility of patient-derived xenograft mouse models.

Nat Rev Cancer 2015 05;15(5):311-6

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA.

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http://www.nature.com/articles/nrc3944
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http://dx.doi.org/10.1038/nrc3944DOI Listing
May 2015

18F-FDG-PET/CT imaging of drug-induced metabolic changes in genetically engineered mouse lung cancer models.

Cold Spring Harb Protoc 2015 Feb 2;2015(2):176-9. Epub 2015 Feb 2.

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032.

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http://dx.doi.org/10.1101/pdb.prot078246DOI Listing
February 2015

Noninvasive imaging of tumor burden and molecular pathways in mouse models of cancer.

Cold Spring Harb Protoc 2015 Feb 2;2015(2):135-44. Epub 2015 Feb 2.

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032.

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http://dx.doi.org/10.1101/pdb.top069930DOI Listing
February 2015

Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.

Br J Haematol 2015 Jan 26;168(2):230-8. Epub 2014 Sep 26.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Haematology, UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1111/bjh.13115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303513PMC
January 2015

Preclinical magnetic resonance imaging in mouse cancer models.

Cold Spring Harb Protoc 2015 Jan 5;2015(1):pdb.prot078253. Epub 2015 Jan 5.

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032.

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https://www.sri.com/sites/default/files/brochures/sri_magnet
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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot07825
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http://dx.doi.org/10.1101/pdb.prot078253DOI Listing
January 2015

Quantitative bioluminescence imaging of mouse tumor models.

Cold Spring Harb Protoc 2015 Jan 5;2015(1):pdb.prot078261. Epub 2015 Jan 5.

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032.

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http://dx.doi.org/10.1101/pdb.prot078261DOI Listing
January 2015

Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo.

Mol Cancer Ther 2014 Sep 15;13(9):2184-93. Epub 2014 Jul 15.

Ludwig Center at Dana-Farber/Harvard, Harvard Medical School, Boston, Massachusetts. Department of Medical Oncology, Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0387DOI Listing
September 2014

Using glow stick chemistry for biological imaging.

Mol Imaging Biol 2014 Aug;16(4):478-87

Lurie Family Imaging Center, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA,

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http://dx.doi.org/10.1007/s11307-014-0721-8DOI Listing
August 2014

Computational repositioning and preclinical validation of pentamidine for renal cell cancer.

Mol Cancer Ther 2014 Jul 1;13(7):1929-1941. Epub 2014 May 1.

BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090263PMC
July 2014

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Nat Genet 2014 Apr 2;46(4):364-70. Epub 2014 Mar 2.

1] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

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http://www.nature.com/articles/ng.2913
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http://dx.doi.org/10.1038/ng.2913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086945PMC
April 2014

Differential disruption of EWS-FLI1 binding by DNA-binding agents.

PLoS One 2013 22;8(7):e69714. Epub 2013 Jul 22.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069714PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718762PMC
February 2014

Targeted imaging of Ewing sarcoma in preclinical models using a 64Cu-labeled anti-CD99 antibody.

Clin Cancer Res 2014 Feb 11;20(3):678-87. Epub 2013 Nov 11.

Authors' Affiliations: Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston Children's Hospital, and Harvard Medical School; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children's Hospital, and Harvard Medical School; Lurie Family Imaging Center, Dana-Farber Cancer Institute; Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School; Department of Pathology, Boston Children's Hospital, and Harvard Medical School, Boston, Massachusetts; and Department of Pediatrics, Columbia University Medical Center, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946397PMC
February 2014

SYK is a critical regulator of FLT3 in acute myeloid leukemia.

Cancer Cell 2014 Feb;25(2):226-42

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, USA; The Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106711PMC
February 2014

Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer.

Clin Cancer Res 2013 Nov 17;19(22):6183-92. Epub 2013 Sep 17.

Authors' Affiliations: Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of Medical Oncology and Radiation Oncology; Belfer Institute for Applied Cancer Science; Ludwig Center at Dana-Farber/Harvard Cancer Center; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and Department of Pediatrics, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838895PMC
November 2013

Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.

Nat Med 2013 Nov 29;19(11):1518-23. Epub 2013 Sep 29.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA. [3] Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA. [4] Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/nm.3328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923315PMC
November 2013

New cast for a new era: preclinical cancer drug development revisited.

J Clin Invest 2013 Sep 3;123(9):3639-45. Epub 2013 Sep 3.

Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI68340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754257PMC
September 2013

In vivo imaging method to distinguish acute and chronic inflammation.

J Vis Exp 2013 Aug 16(78). Epub 2013 Aug 16.

Lurie Family Imaging Center, Dana-Farber Cancer Institute, Harvard Medical School, USA.

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http://dx.doi.org/10.3791/50690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855921PMC
August 2013

Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis.

Angiogenesis 2013 Jul 19;16(3):541-51. Epub 2013 Jan 19.

Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1007/s10456-013-9333-1DOI Listing
July 2013

High-throughput tyrosine kinase activity profiling identifies FAK as a candidate therapeutic target in Ewing sarcoma.

Cancer Res 2013 May 27;73(9):2873-83. Epub 2013 Mar 27.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Children's Hospital Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1944DOI Listing
May 2013

Shikonin, a natural product from the root of Lithospermum erythrorhizon, is a cytotoxic DNA-binding agent.

Eur J Pharm Sci 2013 Apr 17;49(1):18-26. Epub 2013 Feb 17.

Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2013.02.003DOI Listing
April 2013

In Vivo Fluorescent Labeling of Tumor Cells with the HaloTag® Technology.

Curr Chem Genomics 2012 20;6:48-54. Epub 2012 Sep 20.

Lurie Family Imaging Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2174/1875397301206010048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480697PMC
November 2012

Incongruity of imaging using fluorescent 2-DG conjugates compared to 18F-FDG in preclinical cancer models.

Mol Imaging Biol 2012 Oct;14(5):553-60

Lurie Family Imaging Center, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.

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http://link.springer.com/10.1007/s11307-012-0545-3
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http://dx.doi.org/10.1007/s11307-012-0545-3DOI Listing
October 2012

In vivo imaging of inflammatory phagocytes.

Chem Biol 2012 Sep;19(9):1199-209

Lurie Family Imaging Center, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.chembiol.2012.08.007DOI Listing
September 2012

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.

J Clin Invest 2012 Jun 24;122(6):2018-31. Epub 2012 May 24.

Department of Pediatric Oncology and 2Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1172/JCI46231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366394PMC
June 2012

Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells.

PLoS One 2011 25;6(8):e24153. Epub 2011 Aug 25.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024153PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162030PMC
April 2012

Molecular and cellular effects of NEDD8-activating enzyme inhibition in myeloma.

Mol Cancer Ther 2012 Apr 12;11(4):942-51. Epub 2012 Jan 12.

Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755358PMC
April 2012

Anti-inflammatory properties of histone deacetylase inhibitors: a mechanistic study.

J Trauma Acute Care Surg 2012 Feb;72(2):347-53; discussion 353-4

Division of Trauma, Emergency Surgery and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, 165 Cambridge St., Boston, MA 02114, USA.

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https://insights.ovid.com/crossref?an=01586154-201202000-000
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http://dx.doi.org/10.1097/TA.0b013e318243d8b2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782098PMC
February 2012

Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

Proc Natl Acad Sci U S A 2011 Oct 26;108(43):E924-33. Epub 2011 Sep 26.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1106351108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203758PMC
October 2011