Andrew J Schork

Andrew J Schork

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Andrew J Schork

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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study.

Brain Behav Immun 2020 Jun 10. Epub 2020 Jun 10.

CORE-Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2020.06.014DOI Listing
June 2020

Association between Mental Disorders and Subsequent Medical Conditions.

N Engl J Med 2020 04;382(18):1721-1731

From the National Center for Register-based Research (N.C.M., O.P.-R., E.A., M.K.C., S.D., J.-C.P.G.D., T.M.L., P.B.M., K.L.M., C.B.P., L.V.P., B.V., N.W., J.J.M.), Center for Integrated Register-based Research (E.A., P.B.M., C.B.P.), the Departments of Biomedicine-Human Genetics (A.D.B.) and Public Health (M.K.C., M.F.-G., K.M.I., M.V., A.P.), the Center for Integrative Sequencing (A.D.B.), and the Big Data Center for Environment and Health (C.B.P.), Aarhus University, the Lundbeck Foundation Initiative for Integrative Psychiatric Research (E.A., A.D.B., S.D., O.M., P.B.M., K.L.M., M.N., C.B.P., L.V.P., A.J.S., B.V., T.W.), the Center for Genomics and Personalized Medicine (A.D.B.), the Department of Neurology (J.-C.P.G.D.), and the Research Unit, Department of Psychosis (O.M.), Aarhus University Hospital, and the Research Unit for General Practice (M.F.-G., A.R.R., M.V., A.P.), Aarhus, the Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Copenhagen University Hospital (M.E.B., M.N., H.J.S.), Psychiatric Center Copenhagen (L.V.K.), Faculty of Health and Medical Sciences (L.V.K.), the Department of Clinical Medicine (T.W.), and the Lundbeck Foundation GeoGenetics Center, GLOBE Institute (T.W.), University of Copenhagen, Copenhagen, and the Institute of Biological Psychiatry, Mental Health Center Sankt Hans, Mental Health Services Capital Region, Roskilde (A.J.S., T.W.) - all in Denmark; the National Drug and Alcohol Research Centre, University of New South Wales, Sydney (L.D.), the Department of General Practice, Melbourne Medical School, University of Melbourne, Melbourne, VIC (J.M.G.), and the Queensland Brain Institute (C.C.W.L., S.S., J.J.M.), Queensland Centre for Mental Health Research, the Park Centre for Mental Health (C.C.W.L., S.S., T.J.S., H.A.W., J.J.M.), and the School of Public Health, Faculty of Medicine (H.A.W.), University of Queensland, Brisbane - all in Australia; the Departments of Psychology (P.J.) and Developmental Psychology (A.M.R.), Heymans Institute, and the Interdisciplinary Center, Psychopathology and Emotion Regulation (P.J., A.M.R.), University of Groningen, Groningen, the Netherlands; the Department of Health Care Policy, Harvard Medical School, Boston (R.C.K.); the Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ (A.J.S.); the Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand (K.M.S.); Sievert Consulting, Minneapolis (C.S.); and the Institute for Health Metrics and Evaluation, University of Washington, Seattle (H.A.W.).

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http://dx.doi.org/10.1056/NEJMoa1915784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261506PMC
April 2020

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Authors:
Ida E Sønderby Ómar Gústafsson Nhat Trung Doan Derrek P Hibar Sandra Martin-Brevet Abdel Abdellaoui David Ames Katrin Amunts Michael Andersson Nicola J Armstrong Manon Bernard Nicholas Blackburn John Blangero Dorret I Boomsma Janita Bralten Hans-Richard Brattbak Henry Brodaty Rachel M Brouwer Robin Bülow Vince Calhoun Svenja Caspers Gianpiero Cavalleri Chi-Hua Chen Sven Cichon Simone Ciufolini Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Anders M Dale Shareefa Dalvie Paola Dazzan Eco J C de Geus Greig I de Zubicaray Sonja M C de Zwarte Norman Delanty Anouk den Braber Sylvane Desrivières Gary Donohoe Bogdan Draganski Stefan Ehrlich Thomas Espeseth Simon E Fisher Barbara Franke Vincent Frouin Masaki Fukunaga Thomas Gareau David C Glahn Hans Grabe Nynke A Groenewold Jan Haavik Asta Håberg Ryota Hashimoto Jayne Y Hehir-Kwa Andreas Heinz Manon H J Hillegers Per Hoffmann Laurena Holleran Jouke-Jan Hottenga Hilleke E Hulshoff Masashi Ikeda Neda Jahanshad Terry Jernigan Christiane Jockwitz Stefan Johansson Gudrun A Jonsdottir Erik G Jönsson Rene Kahn Tobias Kaufmann Sinead Kelly Masataka Kikuchi Emma E M Knowles Knut K Kolskår John B Kwok Stephanie Le Hellard Costin Leu Jingyu Liu Astri J Lundervold Arvid Lundervold Nicholas G Martin Karen Mather Samuel R Mathias Mark McCormack Katie L McMahon Allan McRae Yuri Milaneschi Clara Moreau Derek Morris David Mothersill Thomas W Mühleisen Robin Murray Jan E Nordvik Lars Nyberg Loes M Olde Loohuis Roel Ophoff Tomas Paus Zdenka Pausova Brenda Penninx Juan M Peralta Bruce Pike Carlos Prieto Sara Pudas Erin Quinlan Daniel S Quintana Céline S Reinbold Tiago Reis Marques Alexandre Reymond Genevieve Richard Borja Rodriguez-Herreros Roberto Roiz-Santiañez Jarek Rokicki James Rucker Perminder Sachdev Anne-Marthe Sanders Sigrid B Sando Lianne Schmaal Peter R Schofield Andrew J Schork Gunter Schumann Jean Shin Elena Shumskaya Sanjay Sisodiya Vidar M Steen Dan J Stein Stacy Steinberg Lachlan Strike Alexander Teumer Anbu Thalamuthu Diana Tordesillas-Gutierrez Jessica Turner Torill Ueland Anne Uhlmann Magnus O Ulfarsson Dennis van 't Ent Dennis van der Meer Neeltje E M van Haren Anja Vaskinn Evangelos Vassos G Bragi Walters Yunpeng Wang Wei Wen Christopher D Whelan Katharina Wittfeld Margie Wright Hidenaga Yamamori Tetyana Zayats Ingrid Agartz Lars T Westlye Sébastien Jacquemont Srdjan Djurovic Hreinn Stefánsson Kári Stefánsson Paul Thompson Ole A Andreassen

Mol Psychiatry 2020 03 3;25(3):584-602. Epub 2018 Oct 3.

NORMENT, K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

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http://www.nature.com/articles/s41380-018-0118-1
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http://dx.doi.org/10.1038/s41380-018-0118-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042770PMC
March 2020

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Authors:
Ida E Sønderby Ómar Gústafsson Nhat Trung Doan Derrek P Hibar Sandra Martin-Brevet Abdel Abdellaoui David Ames Katrin Amunts Michael Andersson Nicola J Armstrong Manon Bernard Nicholas Blackburn John Blangero Dorret I Boomsma Janita Bralten Hans-Richard Brattbak Henry Brodaty Rachel M Brouwer Robin Bülow Vince Calhoun Svenja Caspers Gianpiero Cavalleri Chi-Hua Chen Sven Cichon Simone Ciufolini Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Anders M Dale Shareefa Dalvie Paola Dazzan Eco J C de Geus Greig I de Zubicaray Sonja M C de Zwarte Norman Delanty Anouk den Braber Sylvane Desrivières Gary Donohoe Bogdan Draganski Stefan Ehrlich Thomas Espeseth Simon E Fisher Barbara Franke Vincent Frouin Masaki Fukunaga Thomas Gareau David C Glahn Hans Grabe Nynke A Groenewold Jan Haavik Asta Håberg Ryota Hashimoto Jayne Y Hehir-Kwa Andreas Heinz Manon H J Hillegers Per Hoffmann Laurena Holleran Jouke-Jan Hottenga Hilleke E Hulshoff Masashi Ikeda Neda Jahanshad Terry Jernigan Christiane Jockwitz Stefan Johansson Gudrun A Jonsdottir Erik G Jönsson Rene Kahn Tobias Kaufmann Sinead Kelly Masataka Kikuchi Emma E M Knowles Knut K Kolskår John B Kwok Stephanie Le Hellard Costin Leu Jingyu Liu Astri J Lundervold Arvid Lundervold Nicholas G Martin Karen Mather Samuel R Mathias Mark McCormack Katie L McMahon Allan McRae Yuri Milaneschi Clara Moreau Derek Morris David Mothersill Thomas W Mühleisen Robin Murray Jan E Nordvik Lars Nyberg Loes M Olde Loohuis Roel Ophoff Tomas Paus Zdenka Pausova Brenda Penninx Juan M Peralta Bruce Pike Carlos Prieto Sara Pudas Erin Quinlan Daniel S Quintana Céline S Reinbold Tiago Reis Marques Alexandre Reymond Genevieve Richard Borja Rodriguez-Herreros Roberto Roiz-Santiañez Jarek Rokicki James Rucker Perminder Sachdev Anne-Marthe Sanders Sigrid B Sando Lianne Schmaal Peter R Schofield Andrew J Schork Gunter Schumann Jean Shin Elena Shumskaya Sanjay Sisodiya Vidar M Steen Dan J Stein Stacy Steinberg Lachlan Strike Alexander Teumer Anbu Thalamuthu Diana Tordesillas-Gutierrez Jessica Turner Torill Ueland Anne Uhlmann Magnus O Ulfarsson Dennis van 't Ent Dennis van der Meer Neeltje E M van Haren Anja Vaskinn Evangelos Vassos G Bragi Walters Yunpeng Wang Wei Wen Christopher D Whelan Katharina Wittfeld Margie Wright Hidenaga Yamamori Tetyana Zayats Ingrid Agartz Lars T Westlye Sébastien Jacquemont Srdjan Djurovic Hreinn Stefánsson Kári Stefánsson Paul Thompson Ole A Andreassen

Mol Psychiatry 2020 Mar;25(3):692-695

NORMENT, K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41380-019-0358-8DOI Listing
March 2020

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

Genetic correlations of polygenic disease traits: from theory to practice.

Nat Rev Genet 2019 10;20(10):567-581

Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/s41576-019-0137-zDOI Listing
October 2019

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.

Authors:
Dennis van der Meer Ida E Sønderby Tobias Kaufmann G Bragi Walters Abdel Abdellaoui David Ames Katrin Amunts Micael Andersson Nicola J Armstrong Manon Bernard Nicholas B Blackburn John Blangero Dorret I Boomsma Henry Brodaty Rachel M Brouwer Robin Bülow Wiepke Cahn Vince D Calhoun Svenja Caspers Gianpiero L Cavalleri Christopher R K Ching Sven Cichon Simone Ciufolini Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Shareefa Dalvie Paola Dazzan Eco J C de Geus Greig I de Zubicaray Sonja M C de Zwarte Norman Delanty Anouk den Braber Sylvane Desrivieres Marta Di Forti Joanne L Doherty Gary Donohoe Stefan Ehrlich Else Eising Thomas Espeseth Simon E Fisher Tormod Fladby Oleksandr Frei Vincent Frouin Masaki Fukunaga Thomas Gareau David C Glahn Hans J Grabe Nynke A Groenewold Ómar Gústafsson Jan Haavik Asta K Haberg Ryota Hashimoto Jayne Y Hehir-Kwa Derrek P Hibar Manon H J Hillegers Per Hoffmann Laurena Holleran Jouke-Jan Hottenga Hilleke E Hulshoff Pol Masashi Ikeda Sébastien Jacquemont Neda Jahanshad Christiane Jockwitz Stefan Johansson Erik G Jönsson Masataka Kikuchi Emma E M Knowles John B Kwok Stephanie Le Hellard David E J Linden Jingyu Liu Arvid Lundervold Astri J Lundervold Nicholas G Martin Karen A Mather Samuel R Mathias Katie L McMahon Allan F McRae Sarah E Medland Torgeir Moberget Clara Moreau Derek W Morris Thomas W Mühleisen Robin M Murray Jan E Nordvik Lars Nyberg Loes M Olde Loohuis Roel A Ophoff Michael J Owen Tomas Paus Zdenka Pausova Juan M Peralta Bruce Pike Carlos Prieto Erin Burke Quinlan Céline S Reinbold Tiago Reis Marques James J H Rucker Perminder S Sachdev Sigrid B Sando Peter R Schofield Andrew J Schork Gunter Schumann Jean Shin Elena Shumskaya Ana I Silva Sanjay M Sisodiya Vidar M Steen Dan J Stein Lachlan T Strike Christian K Tamnes Alexander Teumer Anbupalam Thalamuthu Diana Tordesillas-Gutiérrez Anne Uhlmann Magnús Ö Úlfarsson Dennis van 't Ent Marianne B M van den Bree Evangelos Vassos Wei Wen Katharina Wittfeld Margaret J Wright Tetyana Zayats Anders M Dale Srdjan Djurovic Ingrid Agartz Lars T Westlye Hreinn Stefánsson Kári Stefánsson Paul M Thompson Ole A Andreassen

JAMA Psychiatry 2019 Oct 30:1-11. Epub 2019 Oct 30.

Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1001/jamapsychiatry.2019.3779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822096PMC
October 2019

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.

Nat Commun 2019 09 2;10(1):3927. Epub 2019 Sep 2.

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41467-019-11881-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718389PMC
September 2019

Human Disease Variation in the Light of Population Genomics.

Cell 2019 03;177(1):115-131

Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK; Lundbeck Foundation GeoGenetics Centre, Natural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.01.052DOI Listing
March 2019

Genetic risks and clinical rewards.

Nat Genet 2018 09;50(9):1210-1211

Department of Quantitative Medicine, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.

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http://dx.doi.org/10.1038/s41588-018-0213-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383764PMC
September 2018

A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2018 06 28;177(4):454-467. Epub 2018 Apr 28.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1002/ajmg.b.32634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093061PMC
June 2018

Beyond heritability: improving discoverability in imaging genetics.

Hum Mol Genet 2018 05;27(R1):R22-R28

Center for Multimodal Imaging and Genetics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1093/hmg/ddy082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946904PMC
May 2018

Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.

J Am Acad Child Adolesc Psychiatry 2018 02 26;57(2):86-95. Epub 2017 Nov 26.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1016/j.jaac.2017.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806128PMC
February 2018

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.

JAMA Neurol 2017 07;74(7):780-792

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany30Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2017.0469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710535PMC
July 2017

Novel genetic loci associated with hippocampal volume.

Authors:
Derrek P Hibar Hieab H H Adams Neda Jahanshad Ganesh Chauhan Jason L Stein Edith Hofer Miguel E Renteria Joshua C Bis Alejandro Arias-Vasquez M Kamran Ikram Sylvane Desrivières Meike W Vernooij Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Ashley H Beecham Alexa Beiser Manon Bernard Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Qiang Chen Christopher R K Ching Vincent Chouraki Gabriel Cuellar-Partida Fabrice Crivello Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Oliver Grimm Michael E Griswold Tulio Guadalupe Boris A Gutman Johanna Hass Unn K Haukvik David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Kjetil N Jørgensen Nazanin Karbalai Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre F Marquand Mar Matarin Karen A Mather Manuel Mattheisen David R McKay Yuri Milaneschi Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Paul Nyquist Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Lukas Pirpamer Benno Pütz Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Stefan Ropele Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Arvin Saremi Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Stella Trompet Dhananjay Vaidya Jeroen Van der Grond Sven J Van der Lee Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf Thomas Wolfers Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Anton J M De Craen Eco J C De Geus Philip L De Jager Greig I De Zubicaray Ian J Deary Stéphanie Debette Charles DeCarli Norman Delanty Chantal Depondt Anita DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Christian Enzinger Susanne Erk Thomas Espeseth Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Myriam Fornage Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Asta K Håberg Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Matthew Huentelman Hilleke E Hulshoff Pol Masashi Ikeda Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Helena Schmidt Peter R Schofield Sigurdur Sigursson Andrew Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Arthur W Toga Bryan J Traynor Juan Troncoso Magda Tsolaki Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad van der Lugt Nic J A van der Wee Neeltje E M Van Haren Dennis van 't Ent Marie-Jose Van Tol Badri N Vardarajan Bruno Vellas Dick J Veltman Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright Ronald H Zielke Alan B Zonderman Nicholas G Martin Cornelia M Van Duijn Margaret J Wright W T Longstreth Gunter Schumann Hans J Grabe Barbara Franke Lenore J Launer Sarah E Medland Sudha Seshadri Paul M Thompson M Arfan Ikram

Nat Commun 2017 01 18;8:13624. Epub 2017 Jan 18.

Department of Epidemiology, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253632PMC
January 2017

Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.

Mult Scler 2016 12 26;22(14):1783-1793. Epub 2016 Feb 26.

NORMENT, K.G. Jebsen Psychosis Research Centre, Institute of Clinical Medicine, Oslo University Hospital and University of Oslo, Oslo, Norway/Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway/Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001937PMC
December 2016

Pleiotropic Analysis of Lung Cancer and Blood Triglycerides.

J Natl Cancer Inst 2016 12 26;108(12). Epub 2016 Aug 26.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241892PMC
December 2016

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Authors:
Hieab H H Adams Derrek P Hibar Vincent Chouraki Jason L Stein Paul A Nyquist Miguel E Rentería Stella Trompet Alejandro Arias-Vasquez Sudha Seshadri Sylvane Desrivières Ashley H Beecham Neda Jahanshad Katharina Wittfeld Sven J Van der Lee Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Alexa Beiser Manon Bernard Joshua C Bis Laura M E Blanken Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Ganesh Chauhan Qiang Chen Christopher R K Ching Gabriel Cuellar-Partida Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Irina Filippi Tian Ge Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Corina U Greven Oliver Grimm Michael E Griswold Tulio Guadalupe Johanna Hass Unn K Haukvik Saima Hilal Edith Hofer David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee Jiemin Liao David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre Marquand Mar Matarin Karen A Mather Manuel Mattheisen Bernard Mazoyer David R McKay Rebekah McWhirter Yuri Milaneschi Nazanin Mirza-Schreiber Ryan L Muetzel Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Irene Pappa Lukas Pirpamer Sara Pudas Benno Pütz Kumar B Rajan Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Russell Thomson Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Dhananjay Vaidya Jeroen Van der Grond Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Girma Woldehawariat Christiane Wolf Thomas Wolfers Bing Xu Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Neelum T Aggarwal Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Christopher Chen Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Eco J C De Geus Philip L De Jager Greig I de Zubicaray Norman Delanty Chantal Depondt Anita L DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Susanne Erk Thomas Espeseth Denis A Evans Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Hans J Grabe Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Masashi Ikeda M Kamran Ikram Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo W T Longstreth Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Katie L McMahon Francis J McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Peter R Schofield Sigurdur Sigurdsson Andy Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Velandai Srikanth Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Henning Tiemeier Arthur W Toga Bryan J Traynor Juan Troncoso Jessica A Turner Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad Van der Lugt Nic J A Van der Wee Cornelia M Van Duijn Neeltje E M Van Haren Dennis Van T Ent Marie-Jose Van Tol Badri N Vardarajan Dick J Veltman Meike W Vernooij Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright H Ronald Zielke Alan B Zonderman Ian J Deary Charles DeCarli Helena Schmidt Nicholas G Martin Anton J M De Craen Margaret J Wright Lenore J Launer Gunter Schumann Myriam Fornage Barbara Franke Stéphanie Debette Sarah E Medland M Arfan Ikram Paul M Thompson

Nat Neurosci 2016 12 3;19(12):1569-1582. Epub 2016 Oct 3.

Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.

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December 2016

Genetic Markers of Human Evolution Are Enriched in Schizophrenia.

Biol Psychiatry 2016 08 21;80(4):284-292. Epub 2015 Oct 21.

NORMENT, University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Department of Psychiatry, University of California, San Diego, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397584PMC
August 2016

Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms.

PLoS One 2015 8;10(4):e0123057. Epub 2015 Apr 8.

Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, United States of America; Multimodal Imaging Laboratory, University of California San Diego, La Jolla, CA 92093, United States of America; Department of Radiology, University of California San Diego, La Jolla, CA 92093, United States of America; Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390360PMC
March 2016

New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology.

Curr Opin Neurobiol 2016 Feb 8;36:89-98. Epub 2015 Nov 8.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380793PMC
February 2016

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.

Circ Res 2016 Jan 20;118(1):83-94. Epub 2015 Oct 20.

From the Department of Clinical Molecular Biology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (M.L., B.K.A.); Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, University of Oslo, and Research Support Services, Oslo University Hospital, Oslo, Norway (M.L., A.F.); NORMENT - K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (V.Z., A.W., F.B., Y.W., S.D., O.A.A.); Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (V.Z., A.W., F.B., S.D., O.A.A.); Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, University of Oslo, Oslo, Norway (B.K.A.); Deutsches Herzzentrum München, Technische Universität München, Munich, Germany (L.Z., H.S.); Deutsches Zentrum für Herz-Kreislauf-Forschung, partner site Munich Heart Alliance, Munich, Germany (L.Z., H.S.); Multimodal Imaging Laboratory, University of California at San Diego, La Jolla (Y.W., L.K.M., A.J.S., R.S.D., A.M.D., O.A.A.); Department of Neurosciences, University of California, San Diego, La Jolla, (Y.W., A.M.D.); Department of Radiology, University of California, San Diego, La Jolla (L.K.M., R.S.D., A.M.D.); Department of Psychiatry, University of California, San Diego, La Jolla (W.K.T., A.M.D.); Cognitive Sciences Graduate Program, University of California, San Diego, La Jolla, (A.J.S.); Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway (S.R.); Department of Medical Biochemistry, Lovisenberg Diakonale Hospital, Oslo, Norway (S.R., K.M.G.); Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway (S.R., K.M.G.); Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, La Jolla (E.B.-C.); Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands (S.L., A.D.); Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom (C.P.N.,

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609485PMC
January 2016

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies.

PLoS Genet 2015 Dec 29;11(12):e1005717. Epub 2015 Dec 29.

Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456456PMC
December 2015

Modeling the 3D geometry of the cortical surface with genetic ancestry.

Curr Biol 2015 Aug 9;25(15):1988-92. Epub 2015 Jul 9.

Department of Cognitive Science, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Multimodal Imaging Laboratory, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Radiology, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Neuroscience, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Psychiatry, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786069PMC
August 2015

Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study.

Arterioscler Thromb Vasc Biol 2015 Jul 7;35(7):1704-11. Epub 2015 May 7.

From the Departments of Medicine (F.R., A.J.S., E.R.M., J.L.W., D.T.O., S.T.) and Psychiatry (A.X.M., C.M.N.), University of California, La Jolla; and University of Washington, Seattle (S.M.M.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483152PMC
July 2015

Large-scale genomics unveil polygenic architecture of human cortical surface area.

Nat Commun 2015 Jul 20;6:7549. Epub 2015 Jul 20.

1] Multimodal Imaging Laboratory, Department of Radiology, University of California San Diego, La Jolla, California 92037, USA. [2] Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA. [3] Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/ncomms8549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518289PMC
July 2015

Common genetic variants influence human subcortical brain structures.

Authors:
Derrek P Hibar Jason L Stein Miguel E Renteria Alejandro Arias-Vasquez Sylvane Desrivières Neda Jahanshad Roberto Toro Katharina Wittfeld Lucija Abramovic Micael Andersson Benjamin S Aribisala Nicola J Armstrong Manon Bernard Marc M Bohlken Marco P Boks Janita Bralten Andrew A Brown M Mallar Chakravarty Qiang Chen Christopher R K Ching Gabriel Cuellar-Partida Anouk den Braber Sudheer Giddaluru Aaron L Goldman Oliver Grimm Tulio Guadalupe Johanna Hass Girma Woldehawariat Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee Loes M Olde Loohuis Michelle Luciano Christine Macare Karen A Mather Manuel Mattheisen Yuri Milaneschi Kwangsik Nho Martina Papmeyer Adaikalavan Ramasamy Shannon L Risacher Roberto Roiz-Santiañez Emma J Rose Alireza Salami Philipp G Sämann Lianne Schmaal Andrew J Schork Jean Shin Lachlan T Strike Alexander Teumer Marjolein M J van Donkelaar Kristel R van Eijk Raymond K Walters Lars T Westlye Christopher D Whelan Anderson M Winkler Marcel P Zwiers Saud Alhusaini Lavinia Athanasiu Stefan Ehrlich Marina M H Hakobjan Cecilie B Hartberg Unn K Haukvik Angelien J G A M Heister David Hoehn Dalia Kasperaviciute David C M Liewald Lorna M Lopez Remco R R Makkinje Mar Matarin Marlies A M Naber D Reese McKay Margaret Needham Allison C Nugent Benno Pütz Natalie A Royle Li Shen Emma Sprooten Daniah Trabzuni Saskia S L van der Marel Kimm J E van Hulzen Esther Walton Christiane Wolf Laura Almasy David Ames Sampath Arepalli Amelia A Assareh Mark E Bastin Henry Brodaty Kazima B Bulayeva Melanie A Carless Sven Cichon Aiden Corvin Joanne E Curran Michael Czisch Greig I de Zubicaray Allissa Dillman Ravi Duggirala Thomas D Dyer Susanne Erk Iryna O Fedko Luigi Ferrucci Tatiana M Foroud Peter T Fox Masaki Fukunaga J Raphael Gibbs Harald H H Göring Robert C Green Sebastian Guelfi Narelle K Hansell Catharina A Hartman Katrin Hegenscheid Andreas Heinz Dena G Hernandez Dirk J Heslenfeld Pieter J Hoekstra Florian Holsboer Georg Homuth Jouke-Jan Hottenga Masashi Ikeda Clifford R Jack Mark Jenkinson Robert Johnson Ryota Kanai Maria Keil Jack W Kent Peter Kochunov John B Kwok Stephen M Lawrie Xinmin Liu Dan L Longo Katie L McMahon Eva Meisenzahl Ingrid Melle Sebastian Mohnke Grant W Montgomery Jeanette C Mostert Thomas W Mühleisen Michael A Nalls Thomas E Nichols Lars G Nilsson Markus M Nöthen Kazutaka Ohi Rene L Olvera Rocio Perez-Iglesias G Bruce Pike Steven G Potkin Ivar Reinvang Simone Reppermund Marcella Rietschel Nina Romanczuk-Seiferth Glenn D Rosen Dan Rujescu Knut Schnell Peter R Schofield Colin Smith Vidar M Steen Jessika E Sussmann Anbupalam Thalamuthu Arthur W Toga Bryan J Traynor Juan Troncoso Jessica A Turner Maria C Valdés Hernández Dennis van 't Ent Marcel van der Brug Nic J A van der Wee Marie-Jose van Tol Dick J Veltman Thomas H Wassink Eric Westman Ronald H Zielke Alan B Zonderman David G Ashbrook Reinmar Hager Lu Lu Francis J McMahon Derek W Morris Robert W Williams Han G Brunner Randy L Buckner Jan K Buitelaar Wiepke Cahn Vince D Calhoun Gianpiero L Cavalleri Benedicto Crespo-Facorro Anders M Dale Gareth E Davies Norman Delanty Chantal Depondt Srdjan Djurovic Wayne C Drevets Thomas Espeseth Randy L Gollub Beng-Choon Ho Wolfgang Hoffmann Norbert Hosten René S Kahn Stephanie Le Hellard Andreas Meyer-Lindenberg Bertram Müller-Myhsok Matthias Nauck Lars Nyberg Massimo Pandolfo Brenda W J H Penninx Joshua L Roffman Sanjay M Sisodiya Jordan W Smoller Hans van Bokhoven Neeltje E M van Haren Henry Völzke Henrik Walter Michael W Weiner Wei Wen Tonya White Ingrid Agartz Ole A Andreassen John Blangero Dorret I Boomsma Rachel M Brouwer Dara M Cannon Mark R Cookson Eco J C de Geus Ian J Deary Gary Donohoe Guillén Fernández Simon E Fisher Clyde Francks David C Glahn Hans J Grabe Oliver Gruber John Hardy Ryota Hashimoto Hilleke E Hulshoff Pol Erik G Jönsson Iwona Kloszewska Simon Lovestone Venkata S Mattay Patrizia Mecocci Colm McDonald Andrew M McIntosh Roel A Ophoff Tomas Paus Zdenka Pausova Mina Ryten Perminder S Sachdev Andrew J Saykin Andy Simmons Andrew Singleton Hilkka Soininen Joanna M Wardlaw Michael E Weale Daniel R Weinberger Hieab H H Adams Lenore J Launer Stephan Seiler Reinhold Schmidt Ganesh Chauhan Claudia L Satizabal James T Becker Lisa Yanek Sven J van der Lee Maritza Ebling Bruce Fischl W T Longstreth Douglas Greve Helena Schmidt Paul Nyquist Louis N Vinke Cornelia M van Duijn Luting Xue Bernard Mazoyer Joshua C Bis Vilmundur Gudnason Sudha Seshadri M Arfan Ikram Nicholas G Martin Margaret J Wright Gunter Schumann Barbara Franke Paul M Thompson Sarah E Medland

Nature 2015 Apr 21;520(7546):224-9. Epub 2015 Jan 21.

QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia.

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April 2015

MicroRNAs enrichment in GWAS of complex human phenotypes.

BMC Genomics 2015 Apr 16;16:304. Epub 2015 Apr 16.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437677PMC
April 2015

Covariate-modulated local false discovery rate for genome-wide association studies.

Bioinformatics 2014 Aug 7;30(15):2098-104. Epub 2014 Apr 7.

Computational Science Research Center, San Diego State University, San Diego, CA 92182, USA, Cognitive Sciences Graduate Program, University of California at San Diego, La Jolla, CA 92093, USA, Department of Mathematics and Statistics, San Diego State University, San Diego, CA 92182, USA, Institute of Clinical Medicine, University of Oslo, Oslo, 0424, Norway, Multimodal Imaging Laboratory and Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103587PMC
August 2014

Shared common variants in prostate cancer and blood lipids.

Int J Epidemiol 2014 Aug 30;43(4):1205-14. Epub 2014 Apr 30.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway, Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway, Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA, Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, CA, USA, Cognitive Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA, Center for Human Development, University of California at San Diego, La Jolla, CA, USA, the participants acknowledged in Supplementary data, available at IJE online, Department of Medical Genetics, Oslo University Hospital, Oslo, Norway, Department of Radiology, University of California, San Diego, La Jolla, CA, USA, Department of Cancer Prevention, Institute of Cancer Research and Department of Urology, Oslo University Hospital, Oslo, Norway and Department of Neurosciences, University of California, San Diego, La Jolla, CA, USANORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway, Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway, Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA, Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, CA, USA, Cognitive Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA, Center for Human Development, University of California at San Diego, La Jolla, CA, USA, the participants acknowledged in Supplementary data, available at IJE online, Department of Medical Genetics, Oslo University Hospital, Oslo

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August 2014

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.

Authors:
Paul M Thompson Jason L Stein Sarah E Medland Derrek P Hibar Alejandro Arias Vasquez Miguel E Renteria Roberto Toro Neda Jahanshad Gunter Schumann Barbara Franke Margaret J Wright Nicholas G Martin Ingrid Agartz Martin Alda Saud Alhusaini Laura Almasy Jorge Almeida Kathryn Alpert Nancy C Andreasen Ole A Andreassen Liana G Apostolova Katja Appel Nicola J Armstrong Benjamin Aribisala Mark E Bastin Michael Bauer Carrie E Bearden Orjan Bergmann Elisabeth B Binder John Blangero Henry J Bockholt Erlend Bøen Catherine Bois Dorret I Boomsma Tom Booth Ian J Bowman Janita Bralten Rachel M Brouwer Han G Brunner David G Brohawn Randy L Buckner Jan Buitelaar Kazima Bulayeva Juan R Bustillo Vince D Calhoun Dara M Cannon Rita M Cantor Melanie A Carless Xavier Caseras Gianpiero L Cavalleri M Mallar Chakravarty Kiki D Chang Christopher R K Ching Andrea Christoforou Sven Cichon Vincent P Clark Patricia Conrod Giovanni Coppola Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Ian J Deary Eco J C de Geus Anouk den Braber Giuseppe Delvecchio Chantal Depondt Lieuwe de Haan Greig I de Zubicaray Danai Dima Rali Dimitrova Srdjan Djurovic Hongwei Dong Gary Donohoe Ravindranath Duggirala Thomas D Dyer Stefan Ehrlich Carl Johan Ekman Torbjørn Elvsåshagen Louise Emsell Susanne Erk Thomas Espeseth Jesen Fagerness Scott Fears Iryna Fedko Guillén Fernández Simon E Fisher Tatiana Foroud Peter T Fox Clyde Francks Sophia Frangou Eva Maria Frey Thomas Frodl Vincent Frouin Hugh Garavan Sudheer Giddaluru David C Glahn Beata Godlewska Rita Z Goldstein Randy L Gollub Hans J Grabe Oliver Grimm Oliver Gruber Tulio Guadalupe Raquel E Gur Ruben C Gur Harald H H Göring Saskia Hagenaars Tomas Hajek Geoffrey B Hall Jeremy Hall John Hardy Catharina A Hartman Johanna Hass Sean N Hatton Unn K Haukvik Katrin Hegenscheid Andreas Heinz Ian B Hickie Beng-Choon Ho David Hoehn Pieter J Hoekstra Marisa Hollinshead Avram J Holmes Georg Homuth Martine Hoogman L Elliot Hong Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Kristy S Hwang Clifford R Jack Mark Jenkinson Caroline Johnston Erik G Jönsson René S Kahn Dalia Kasperaviciute Sinead Kelly Sungeun Kim Peter Kochunov Laura Koenders Bernd Krämer John B J Kwok Jim Lagopoulos Gonzalo Laje Mikael Landen Bennett A Landman John Lauriello Stephen M Lawrie Phil H Lee Stephanie Le Hellard Herve Lemaître Cassandra D Leonardo Chiang-Shan Li Benny Liberg David C Liewald Xinmin Liu Lorna M Lopez Eva Loth Anbarasu Lourdusamy Michelle Luciano Fabio Macciardi Marise W J Machielsen Glenda M Macqueen Ulrik F Malt René Mandl Dara S Manoach Jean-Luc Martinot Mar Matarin Karen A Mather Manuel Mattheisen Morten Mattingsdal Andreas Meyer-Lindenberg Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Eva Meisenzahl Ingrid Melle Yuri Milaneschi Sebastian Mohnke Grant W Montgomery Derek W Morris Eric K Moses Bryon A Mueller Susana Muñoz Maniega Thomas W Mühleisen Bertram Müller-Myhsok Benson Mwangi Matthias Nauck Kwangsik Nho Thomas E Nichols Lars-Göran Nilsson Allison C Nugent Lars Nyberg Rene L Olvera Jaap Oosterlaan Roel A Ophoff Massimo Pandolfo Melina Papalampropoulou-Tsiridou Martina Papmeyer Tomas Paus Zdenka Pausova Godfrey D Pearlson Brenda W Penninx Charles P Peterson Andrea Pfennig Mary Phillips G Bruce Pike Jean-Baptiste Poline Steven G Potkin Benno Pütz Adaikalavan Ramasamy Jerod Rasmussen Marcella Rietschel Mark Rijpkema Shannon L Risacher Joshua L Roffman Roberto Roiz-Santiañez Nina Romanczuk-Seiferth Emma J Rose Natalie A Royle Dan Rujescu Mina Ryten Perminder S Sachdev Alireza Salami Theodore D Satterthwaite Jonathan Savitz Andrew J Saykin Cathy Scanlon Lianne Schmaal Hugo G Schnack Andrew J Schork S Charles Schulz Remmelt Schür Larry Seidman Li Shen Jody M Shoemaker Andrew Simmons Sanjay M Sisodiya Colin Smith Jordan W Smoller Jair C Soares Scott R Sponheim Emma Sprooten John M Starr Vidar M Steen Stephen Strakowski Lachlan Strike Jessika Sussmann Philipp G Sämann Alexander Teumer Arthur W Toga Diana Tordesillas-Gutierrez Daniah Trabzuni Sarah Trost Jessica Turner Martijn Van den Heuvel Nic J van der Wee Kristel van Eijk Theo G M van Erp Neeltje E M van Haren Dennis van 't Ent Marie-Jose van Tol Maria C Valdés Hernández Dick J Veltman Amelia Versace Henry Völzke Robert Walker Henrik Walter Lei Wang Joanna M Wardlaw Michael E Weale Michael W Weiner Wei Wen Lars T Westlye Heather C Whalley Christopher D Whelan Tonya White Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf David Zilles Marcel P Zwiers Anbupalam Thalamuthu Peter R Schofield Nelson B Freimer Natalia S Lawrence Wayne Drevets

Brain Imaging Behav 2014 Jun;8(2):153-82

Imaging Genetics Center, Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90033, USA,

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http://dx.doi.org/10.1007/s11682-013-9269-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008818PMC
June 2014

Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes.

Hypertension 2014 Apr 6;63(4):819-26. Epub 2014 Jan 6.

Department of Radiology, University of California, San Diego, 8950 Villa La Jolla Dr, Suite C101, La Jolla, CA 92037-0841. and Ole A. Andreassen, NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Ullevål, PO Box 4956 Nydalen, 0424 Oslo, Norway. Email

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.113.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984909PMC
April 2014

Genetic implication of a novel thiamine transporter in human hypertension.

J Am Coll Cardiol 2014 Apr 5;63(15):1542-55. Epub 2014 Feb 5.

Department of Medicine, University of California at San Diego (UCSD), La Jolla, California; Veterans Affairs San Diego Healthcare System, San Diego, California; Department of Pharmacology and the Institute for Genomic Medicine, UCSD, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992204PMC
April 2014

Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].

J Am Coll Cardiol 2014 Feb 16;63(4):358-68. Epub 2013 Oct 16.

Department of Medicine, University of California at San Diego, San Diego, California; Institute for Genomic Medicine, University of California at San Diego, San Diego, California; Department of Pharmacology, University of California at San Diego, San Diego, California; VA San Diego Healthcare System, San Diego, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946708PMC
February 2014

Genetic variation at the delta-sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs.

J Neurochem 2013 Dec 19;127(6):750-61. Epub 2013 Jul 19.

Departments of Medicine (0838) and Pharmacology and Institute for Genomic Medicine, VA San Diego Healthcare System University of California, San Diego, California, USA.

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http://dx.doi.org/10.1111/jnc.12346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833977PMC
December 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://petercroucher.com/wp-content/uploads/2013/10/51_Natur
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Autonomic and hemodynamic origins of pre-hypertension: central role of heredity.

J Am Coll Cardiol 2012 Jun;59(24):2206-16

Department of Medicine, University of California-San Diego, and V.A. San Diego Healthcare System, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S073510971201143
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http://dx.doi.org/10.1016/j.jacc.2012.02.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374873PMC
June 2012

Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypes.

Genet Epidemiol 2007 Nov;31(7):789-96

Center for Human Genetics and Genomics, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1002/gepi.20241DOI Listing
November 2007