Andrew J Sandford

Andrew J Sandford

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Andrew J Sandford

Andrew J Sandford

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Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea.

Authors:
Andrew J Sandford Amanda Ha David A Ngan Loubna Akhabir Aabida Saferali Nurit Fox A J Hirsch Allen Simon C Warby Stephan F van Eeden Najib T Ayas

PLoS One 2019 17;14(1):e0210732. Epub 2019 Jan 17.

UBC Hospital Sleep Disorders Program, Division of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210732PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336279PMC
October 2019

Abbott RealTime MTB and MTB RIF/INH assays for the diagnosis of tuberculosis and rifampicin/isoniazid resistance.

Authors:
Ming-Gui Wang Miao Xue Shou-Quan Wu Miao-Miao Zhang Yu Wang Qianqian Liu Andrew J Sandford Jian-Qing He

Infect Genet Evol 2019 07 20;71:54-59. Epub 2019 Mar 20.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2019.03.012DOI Listing
July 2019

Association Study of Myosin Heavy Chain 15 Polymorphisms with Asthma Susceptibility in Chinese Han.

Authors:
Guo Chen Lan Luo Miao-Miao Zhang Shou-Quan Wu Yu Wang Andrew J Sandford Jian-Qing He

Biomed Res Int 2019 18;2019:3805405. Epub 2019 Feb 18.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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https://www.hindawi.com/journals/bmri/2019/3805405/
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http://dx.doi.org/10.1155/2019/3805405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398074PMC
July 2019

Polymorphisms in Toll-Like Receptor 10 and Tuberculosis Susceptibility: Evidence from Three Independent Series.

Authors:
Yu Wang Miao-Miao Zhang Wei-Wei Huang Shou-Quan Wu Ming-Gui Wang Xiao-Yan Tang Andrew J Sandford Jian-Qing He

Front Immunol 2018 23;9:309. Epub 2018 Feb 23.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.3389/fimmu.2018.00309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829065PMC
March 2019

Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity.

Authors:
Yu Wang Xi Xiang Wei-Wei Huang Andrew J Sandford Shou-Quan Wu Miao-Miao Zhang Ming-Gui Wang Guo Chen Jian-Qing He

Sci Rep 2019 Feb 18;9(1):2217. Epub 2019 Feb 18.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1038/s41598-018-38452-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379441PMC
February 2019

Association of the variant rs5743557 with susceptibility to tuberculosis.

Authors:
Miaomiao Zhang Jing Wang Yu Wang Shouquan Wu Andrew J Sandford Jun Luo Jian-Qing He

J Thorac Dis 2019 Feb;11(2):583-594

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.

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http://dx.doi.org/10.21037/jtd.2019.01.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409282PMC
February 2019

Variants of TLR1 associated with tuberculosis susceptibility in the Chinese Tibetan population but not in Han Chinese.

Authors:
Miaomiao Zhang Xiaoyan Tang Yu Wang Shouquan Wu Minggui Wang Qianqian Liu Andrew J Sandford Jian-Qing He

Infect Genet Evol 2018 07 15;61:53-59. Epub 2018 Feb 15.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2018.02.021DOI Listing
July 2018

Association between tobacco smoking and drug-resistant tuberculosis.

Authors:
Ming-Gui Wang Wei-Wei Huang Yu Wang Yun-Xia Zhang Miao-Miao Zhang Shou-Quan Wu Andrew J Sandford Jian-Qing He

Infect Drug Resist 2018 12;11:873-887. Epub 2018 Jun 12.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.

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http://dx.doi.org/10.2147/IDR.S164596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003534PMC
June 2018

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.

Authors:
Yuka Asai Aida Eslami C Dorien van Ginkel Loubna Akhabir Ming Wan David Yin George Ellis Moshe Ben-Shoshan Ingo Marenholz David Martino Manuel A Ferreira Katrina Allen Bruce Mazer Hans de Groot Nicolette W de Jong Roy Gerth van Wijk Anthony E J Dubois Sarah Grosche Sarah Ashley Franz Rüschendorf Birgit Kalb Kirsten Beyer Markus M Nöthen Young-Ae Lee Rick Chin Stephen Cheuk Joshua Hoffman Eric Jorgensen John S Witte Ronald B Melles Xiumei Hong Xiaobin Wang Jennie Hui Arthur W Bill Musk Michael Hunter Alan L James Gerard H Koppelman Andrew J Sandford Ann E Clarke Denise Daley

J Allergy Clin Immunol 2018 04 8;141(4):1513-1516. Epub 2018 Jan 8.

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.047DOI Listing
April 2018

Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy.

Authors:
Yuka Asai Aida Eslami C Dorien van Ginkel Loubna Akhabir Ming Wan George Ellis Moshe Ben-Shoshan David Martino Manuel A Ferreira Katrina Allen Bruce Mazer Hans de Groot Nicolette W de Jong Roy N Gerth van Wijk Anthony E J Dubois Rick Chin Stephen Cheuk Joshua Hoffman Eric Jorgensen John S Witte Ronald B Melles Xiumei Hong Xiaobin Wang Jennie Hui Arthur W Bill Musk Michael Hunter Alan L James Gerard H Koppelman Andrew J Sandford Ann E Clarke Denise Daley

J Allergy Clin Immunol 2018 03 10;141(3):991-1001. Epub 2017 Oct 10.

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.09.015DOI Listing
March 2018

Genetic Polymorphisms of Glutathione S-Transferase P1 (GSTP1) and the Incidence of Anti-Tuberculosis Drug-Induced Hepatotoxicity.

Authors:
Shouquan Wu You-Juan Wang Xiaoyan Tang Yu Wang Jingcan Wu Guiyi Ji Miaomiao Zhang Guo Chen Qianqian Liu Andrew J Sandford Jian-Qing He

PLoS One 2016 9;11(6):e0157478. Epub 2016 Jun 9.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157478PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900521PMC
July 2017

Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population.

Authors:
Yu Wang Xi Xiang Shou-Quan Wu Guo Chen Miao-Miao Zhang Ming-Gui Wang Feng-Juan Wang Andrew J Sandford Jian-Qing He

Infect Genet Evol 2017 07 5;51:198-202. Epub 2017 Apr 5.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2017.04.001DOI Listing
July 2017

Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 Modulation.

Authors:
Anthony C Tang Aabida Saferali Gengming He Andrew J Sandford Lisa J Strug Stuart E Turvey

J Infect Dis 2017 01;215(2):293-302

Department of Microbiology & Immunology, University of British Columbia.

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http://dx.doi.org/10.1093/infdis/jiw516DOI Listing
January 2017

Heterozygote Advantage of the rs3794624 Polymorphism in CYBA for Resistance to Tuberculosis in Two Chinese Populations.

Authors:
Qianqian Liu Shouquan Wu Miao Xue Andrew J Sandford Jingcan Wu Yu Wang Guo Chen Chuanmin Tao Yin Tang Yulin Feng Jun Luo Jian-Qing He

Sci Rep 2016 11 30;6:38213. Epub 2016 Nov 30.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1038/srep38213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128811PMC
November 2016

Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease.

Authors:
Yu Wang Karey Shumansky Don D Sin S F Paul Man Loubna Akhabir John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford Jian-Qing He

Int J Clin Exp Pathol 2015 1;8(10):13125-35. Epub 2015 Oct 1.

Department of Respiratory and Critical Medicine, West China Hospital of Sichuan University Chengdu, Sichuan Province, China ; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680456PMC
October 2016

Analysis of silent information regulator 1 (SIRT1) gene polymorphisms in antituberculosis- drug-induced hepatotoxicity in a prospective cohort study.

Authors:
Yu Wang Xiu-Ying Yan Jing-Can Wu Gui-Yi Ji Shou-Quan Wu Wei-Wei Huang Guo Chen Andrew J Sandford Jian-Qing He

Int J Clin Pharmacol Ther 2016 Oct;54(10):775-81

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http://www.dustri.com/article_response_page.html?artId=14198
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http://dx.doi.org/10.5414/CP202506DOI Listing
October 2016

Rifampicin-induced antineutrophil cytoplasmic antibody-positive vasculitis: a case report and review of the literature.

Authors:
Guiyi Ji Xuemei Zeng Andrew J Sandford Jian-Qing He

Int J Clin Pharmacol Ther 2016 Oct;54(10):804-7

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http://dx.doi.org/10.5414/CP202576DOI Listing
October 2016

The BuMPy Road to COPD Gene Discovery.

Authors:
Andrew J Sandford

EBioMedicine 2016 Mar 6;5:18-9. Epub 2016 Feb 6.

Centre for Heart Lung Innovation, UBC and St. Paul's Hospital, 1081 Burrard Street, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1016/j.ebiom.2016.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816841PMC
March 2016

Polymorphisms associated with expression of BPIFA1/BPIFB1 and lung disease severity in cystic fibrosis.

Authors:
Aabida Saferali Ma'en Obeidat Jean-Christophe Bérubé Maxime Lamontagne Yohan Bossé Michel Laviolette Ke Hao David C Nickle Wim Timens Don D Sin Dirkje S Postma Lisa J Strug Paul J Gallins Peter D Paré Colin D Bingle Andrew J Sandford

Am J Respir Cell Mol Biol 2015 Nov;53(5):607-14

1 Centre for Heart Lung Innovation, UBC and St. Paul's Hospital, Vancouver, British Columbia.

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http://dx.doi.org/10.1165/rcmb.2014-0182OCDOI Listing
November 2015

Molecular mechanisms underlying variations in lung function: a systems genetics analysis.

Authors:
Ma'en Obeidat Ke Hao Yohan Bossé David C Nickle Yunlong Nie Dirkje S Postma Michel Laviolette Andrew J Sandford Denise D Daley James C Hogg W Mark Elliott Nick Fishbane Wim Timens Pirro G Hysi Jaakko Kaprio James F Wilson Jennie Hui Rajesh Rawal Holger Schulz Beate Stubbe Caroline Hayward Ozren Polasek Marjo-Riitta Järvelin Jing Hua Zhao Deborah Jarvis Mika Kähönen Nora Franceschini Kari E North Daan W Loth Guy G Brusselle Albert Vernon Smith Vilmundur Gudnason Traci M Bartz Jemma B Wilk George T O'Connor Patricia A Cassano Wenbo Tang Louise V Wain María Soler Artigas Sina A Gharib David P Strachan Don D Sin Martin D Tobin Stephanie J London Ian P Hall Peter D Paré

Lancet Respir Med 2015 Oct 21;3(10):782-95. Epub 2015 Sep 21.

University of British Columbia Center for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(15)00380-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021067PMC
October 2015

Transcriptomic profiling of peripheral blood CD4⁺ T-cells in asthmatics with and without depression.

Authors:
Ting Wang Yu-Lin Ji Yin-Yin Yang Xing-Yu Xiong I-Ming Wang Andrew J Sandford Zong-An Liang Jian-Qing He

Gene 2015 Jul 11;565(2):282-7. Epub 2015 Apr 11.

Department of Respiratory and Critical Care Medicine, West China Medical School/West China Hospital, Chengdu, Sichuan Province, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.04.029DOI Listing
July 2015

Association of CYBB polymorphisms with tuberculosis susceptibility in the Chinese Han population.

Authors:
Qianqian Liu Jing Wang Andrew J Sandford Jingcan Wu Yu Wang Shouquan Wu Guiyi Ji Guo Chen Yulin Feng Chuanmin Tao Jian-Qing He

Infect Genet Evol 2015 Jul 27;33:169-75. Epub 2015 Apr 27.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15671348150016
Publisher Site
http://dx.doi.org/10.1016/j.meegid.2015.04.026DOI Listing
July 2015

Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.

Authors:
Aabida Saferali Jee Lee Don D Sin Farshid N Rouhani Mark L Brantly Andrew J Sandford

PLoS One 2014 24;9(4):e95600. Epub 2014 Apr 24.

UBC James Hogg Research Centre, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998943PMC
January 2015

Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region.

Authors:
Loubna Akhabir Jean-Christophe Bérubé Yohan Bossé Michel Laviolette Ke Hao David C Nickle Wim Timens Don D Sin Peter D Paré Dirkje S Postma Andrew J Sandford

J Allergy Clin Immunol 2014 Sep 18;134(3):729-31. Epub 2014 Apr 18.

UBC James Hogg Research Centre, Heart + Lung Institute, St Paul's Hospital, Vancouver, British Columbia, Canada; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jaci.2014.02.039DOI Listing
September 2014

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.

Authors:
Gian Andri Thun Medea Imboden Ilaria Ferrarotti Ashish Kumar Ma'en Obeidat Michele Zorzetto Margot Haun Ivan Curjuric Alexessander Couto Alves Victoria E Jackson Eva Albrecht Janina S Ried Alexander Teumer Lorna M Lopez Jennifer E Huffman Stefan Enroth Yohan Bossé Ke Hao Wim Timens Ulf Gyllensten Ozren Polasek James F Wilson Igor Rudan Caroline Hayward Andrew J Sandford Ian J Deary Beate Koch Eva Reischl Holger Schulz Jennie Hui Alan L James Thierry Rochat Erich W Russi Marjo-Riitta Jarvelin David P Strachan Ian P Hall Martin D Tobin Morten Dahl Sune Fallgaard Nielsen Børge G Nordestgaard Florian Kronenberg Maurizio Luisetti Nicole M Probst-Hensch

PLoS Genet 2013 22;9(8):e1003585. Epub 2013 Aug 22.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1003585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749935PMC
March 2014

Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema.

Authors:
Takeo Ishii Raja T Abboud Alison M Wallace John C English Harvey O Coxson Richard J Finley Karey Shumansky Peter D Paré Andrew J Sandford

Eur Respir J 2014 Jan 30;43(1):82-91. Epub 2013 Jul 30.

Institute for Heart and Lung Health, St. Paul's Hospital, Vancouver, BC.

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http://dx.doi.org/10.1183/09031936.00174612DOI Listing
January 2014

Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease.

Authors:
Farzian Aminuddin Tillie-Louise Hackett Dorota Stefanowicz Aabida Saferali Peter D Paré Amund Gulsvik Per Bakke Michael H Cho Augusto Litonjua David A Lomas Wayne H Anderson Terri H Beaty Edwin K Silverman Andrew J Sandford

BMC Pulm Med 2013 Nov 6;13:64. Epub 2013 Nov 6.

The University of British Columbia James Hogg Research Centre, Providence Heart + Lung Institute, Vancouver, Canada.

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http://dx.doi.org/10.1186/1471-2466-13-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827989PMC
November 2013

HLA-DQB1*02 and DQB1*06:03P are associated with peanut allergy.

Authors:
Anne-Marie Madore Vanessa T Vaillancourt Yuka Asai Reza Alizadehfar Moshe Ben-Shoshan Deborah L Michel Anita L Kozyrskyj Allan Becker Moira Chan-Yeung Ann E Clarke Peter Hull Denise Daley Andrew J Sandford Catherine Laprise

Eur J Hum Genet 2013 Oct 27;21(10):1181-4. Epub 2013 Feb 27.

Département des Sciences Fondamentales, Université du Québec à Chicoutimi, Saguenay, Québec, Canada.

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http://dx.doi.org/10.1038/ejhg.2013.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778350PMC
October 2013

Selection of suitable housekeeping genes for real-time quantitative PCR in CD4(+) lymphocytes from asthmatics with or without depression.

Authors:
Ting Wang Zong-An Liang Andrew J Sandford Xing-Yu Xiong Yin-Yin Yang Yu-Lin Ji Jian-Qing He

PLoS One 2012 24;7(10):e48367. Epub 2012 Oct 24.

Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan Province, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048367PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480507PMC
April 2013

Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia.

Authors:
Salman Ali Aaron F Hirschfeld Matthew L Mayer Edgardo S Fortuno Nathan Corbett Maia Kaplan Shirley Wang Julia Schneiderman Christopher D Fjell Jin Yan Loubna Akhabir Farzian Aminuddin Nico Marr Thierry Lacaze-Masmonteil Richard G Hegele Allan Becker Moira Chan-Yeung Robert E W Hancock Tobias R Kollmann Denise Daley Andrew J Sandford Pascal M Lavoie Stuart E Turvey

J Immunol 2013 Apr 13;190(8):3949-58. Epub 2013 Mar 13.

Department of Pediatrics, British Columbia Children's Hospital and Child & Family Research Institute, University of British Columbia, Vancouver, British Columbia V6H 3V4, Canada.

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http://dx.doi.org/10.4049/jimmunol.1201015DOI Listing
April 2013

Personalised medicine and asthma diagnostics/management.

Authors:
Samuel J Wadsworth Andrew J Sandford

Curr Allergy Asthma Rep 2013 Feb;13(1):118-29

UBC James Hogg Research Centre, Institute for Heart and Lung Health, St Paul's Hospital, 166-1081 Burrard St, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1007/s11882-012-0325-9DOI Listing
February 2013

Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes.

Authors:
Denise Daley Julie E Park Jian-Qing He Jin Yan Loubna Akhabir Dorota Stefanowicz Allan B Becker Moira Chan-Yeung Yohan Bossé Anita L Kozyrskyj Alan L James Arthur W Musk Catherine Laprise Richard G Hegele Peter D Paré Andrew J Sandford

J Allergy Clin Immunol 2012 Dec 9;130(6):1284-93. Epub 2012 Oct 9.

University of British Columbia James Hogg Research Centre, Institute for Heart and Lung Health, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jaci.2012.07.051DOI Listing
December 2012

The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD).

Authors:
Jee Lee Andrew J Sandford John E Connett Jin Yan Tammy Mui Yuexin Li Denise Daley Nicholas R Anthonisen Angela Brooks-Wilson S F Paul Man Don D Sin

PLoS One 2012 25;7(4):e35567. Epub 2012 Apr 25.

The Providence Heart and Lung Institute at St. Paul's Hospital, The UBC James Hogg Research Centre & Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035567PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338848PMC
September 2012

Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study.

Authors:
Alison M Wallace Becky A Mercer Jianqing He Robert F Foronjy Domenico Accili Andrew J Sandford Peter D Paré Jeanine M D'Armiento

Respir Res 2012 Sep 19;13:79. Epub 2012 Sep 19.

Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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http://dx.doi.org/10.1186/1465-9921-13-79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509005PMC
September 2012

Molecular signature of smoking in human lung tissues.

Authors:
Yohan Bossé Dirkje S Postma Don D Sin Maxime Lamontagne Christian Couture Nathalie Gaudreault Philippe Joubert Vivien Wong Mark Elliott Maarten van den Berge Corry A Brandsma Catherine Tribouley Vladislav Malkov Jeffrey A Tsou Gregory J Opiteck James C Hogg Andrew J Sandford Wim Timens Peter D Paré Michel Laviolette

Cancer Res 2012 Aug 1;72(15):3753-63. Epub 2012 Jun 1.

Department of Molecular Medicine, Laval University, Québec, QC, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1160DOI Listing
August 2012

NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease.

Authors:
Andrew J Sandford Deepti Malhotra H Marike Boezen Mateusz Siedlinski Dirkje S Postma Vivien Wong Loubna Akhabir Jian-Qing He John E Connett Nicholas R Anthonisen Peter D Paré Shyam Biswal

Physiol Genomics 2012 Aug 12;44(15):754-63. Epub 2012 Jun 12.

UBC James Hogg Research Centre, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/physiolgenomics.00027.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774584PMC
August 2012

Effect of gene environment interactions on lung function and cardiovascular disease in COPD.

Authors:
Tillie-Louise Hackett Dorota Stefanowicz Farzian Aminuddin Don D Sin John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Int J Chron Obstruct Pulmon Dis 2011 10;6:277-87. Epub 2011 May 10.

University of British Columbia, James Hogg Research Laboratories, St Paul's Hospital, Division of Respirology, Department of Medicine, Vancouver, BC, Canada.

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http://dx.doi.org/10.2147/COPD.S18279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144847PMC
November 2011

Effect of heme oxygenase-1 polymorphisms on lung function and gene expression.

Authors:
Goh Tanaka Farzian Aminuddin Loubna Akhabir Jian-Qing He Karey Shumansky John E Connett Nicholas R Anthonisen Raja T Abboud Peter D Paré Andrew J Sandford

BMC Med Genet 2011 Sep 8;12:117. Epub 2011 Sep 8.

UBC James Hogg Research Center, Providence Heart + Lung Institute, St, Paul's Hospital, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1186/1471-2350-12-117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180266PMC
September 2011

Genome-wide association studies for discovery of genes involved in asthma.

Authors:
Loubna Akhabir Andrew J Sandford

Respirology 2011 Apr;16(3):396-406

University of British Columbia James Hogg Research Centre, Providence Heart + Lung Institute, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1111/j.1440-1843.2011.01939.x
Publisher Site
http://dx.doi.org/10.1111/j.1440-1843.2011.01939.xDOI Listing
April 2011

TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.

Authors:
Christoph J Blohmke Julie Park Aaron F Hirschfeld Rachel E Victor Julia Schneiderman Dorota Stefanowicz Mark A Chilvers Peter R Durie Mary Corey Julian Zielenski Ruslan Dorfman Andrew J Sandford Denise Daley Stuart E Turvey

J Immunol 2010 Dec 10;185(12):7731-8. Epub 2010 Nov 10.

Department of Paediatrics, BC Children's Hospital and Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4049/jimmunol.1001513DOI Listing
December 2010

Asthma susceptibility: The role of transforming growth factor beta1.

Authors:
Andrew J Sandford

Respirology 2010 May;15(4):583-4

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http://dx.doi.org/10.1111/j.1440-1843.2010.01760.xDOI Listing
May 2010

Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging.

Authors:
Tammy S Y Mui Julie M Man Janet E McElhaney Andrew J Sandford Harvey O Coxson C Laird Birmingham Yuexin Li S F Paul Man Don D Sin

J Am Geriatr Soc 2009 Dec;57(12):2372-4

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http://dx.doi.org/10.1111/j.1532-5415.2009.02589.xDOI Listing
December 2009

Role of genetic susceptibility to latent adenoviral infection and decreased lung function.

Authors:
Ikuma Kasuga James C Hogg Peter D Paré Shizu Hayashi Edward G Sedgwick Jian Ruan Alison M Wallace Jian-Qing He Xiaozhu Zhang Andrew J Sandford

Respir Med 2009 Nov 6;103(11):1672-80. Epub 2009 Jun 6.

The James Hogg iCAPTURE Centre, University of British Columbia, St Paul's Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1016/j.rmed.2009.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757510PMC
November 2009

Lack of association of TIM3 polymorphisms and allergic phenotypes.

Authors:
Jian Zhang Denise Daley Loubna Akhabir Dorota Stefanowicz Moira Chan-Yeung Allan B Becker Catherine Laprise Peter D Paré Andrew J Sandford

BMC Med Genet 2009 Jun 30;10:62. Epub 2009 Jun 30.

James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St, Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1186/1471-2350-10-62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711936PMC
June 2009

Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues.

Authors:
Karine Tremblay Denise Daley Annie Chamberland Mathieu Lemire Alexandre Montpetit Michel Laviolette Arthur W Musk Alan L James Moira Chan-Yeung Allan Becker Anita L Kozyrskyj Andrew J Sandford Thomas J Hudson Peter D Paré Catherine Laprise

J Allergy Clin Immunol 2008 Sep;122(3):529-36.e17

Hôpital Laval, Université Laval, Quebec, Canada.

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http://dx.doi.org/10.1016/j.jaci.2008.05.049DOI Listing
September 2008

Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema.

Authors:
Alison M Wallace Andrew J Sandford John C English Kelly M Burkett Hong Li Richard J Finley Nestor L Müller Harvey O Coxson Peter D Paré Raja T Abboud

COPD 2008 Feb;5(1):13-23

University of British Columbia (UBC) James Hogg iCAPTURE Centre, St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1080/15412550701817789DOI Listing
February 2008

Recent advances in asthma genetics.

Authors:
Jian Zhang Peter D Paré Andrew J Sandford

Respir Res 2008 Jan 15;9. Epub 2008 Jan 15.

James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St, Paul's Hospital, Vancouver, B,C,, V6Z 1Y6,

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http://dx.doi.org/10.1186/1465-9921-9-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244620PMC
January 2008

Promoter polymorphism and expression of beta-arrestin 2 in neutrophils.

Authors:
Xiaozhu Zhang Jian-Qing He Lily Ding Peter D Paré Andrew J Sandford

Clin Chim Acta 2007 Oct 31;385(1-2):79-80. Epub 2007 Jul 31.

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http://dx.doi.org/10.1016/j.cca.2007.07.021DOI Listing
October 2007

Transforming growth factor-beta1 polymorphisms, airway responsiveness and lung function decline in smokers.

Authors:
Emiko Ogawa Jian Ruan John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Respir Med 2007 May 27;101(5):938-43. Epub 2006 Oct 27.

James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St. Paul's Hospital, Room 166, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6.

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http://dx.doi.org/10.1016/j.rmed.2006.09.008DOI Listing
May 2007

Association of Hck genetic polymorphisms with gene expression and COPD.

Authors:
Xiaozhu Zhang Salahaddin Mahmudi-Azer John E Connett Nicholas R Anthonisen Jian-Qing He Peter D Paré Andrew J Sandford

Hum Genet 2007 Jan 26;120(5):681-90. Epub 2006 Sep 26.

James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research , St. Paul's Hospital, University of British Columbia, 1081 Burrard Street, Room 166, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s00439-006-0253-7DOI Listing
January 2007

Variants in the glutamate-cysteine-ligase gene are associated with cystic fibrosis lung disease.

Authors:
Edward F McKone Jing Shao Daisy D Frangolias Cassie L Keener Cynthia A Shephard Federico M Farin Mark R Tonelli Peter D Pare Andrew J Sandford Moira L Aitken Terrance J Kavanagh

Am J Respir Crit Care Med 2006 Aug 11;174(4):415-9. Epub 2006 May 11.

Department of Environmental and Occupational Health Sciences, University of Washington Mail Box 354695, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1164/rccm.200508-1281OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648118PMC
August 2006

Relationship of matrix metalloproteinase mRNA expression and genetic polymorphisms to emphysema.

Authors:
Raja T Abboud Alison M Wallace John C English Nestor L Müller Harvey Coxson Peter D Paré Andrew J Sandford

Proc Am Thorac Soc 2006 Aug;3(6):475

Division of Respiratory Medicine, University of British Columbia, 2775 Heather Street, Vancouver, BC, V5Z 3J5 Canada.

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http://dx.doi.org/10.1513/pats.200603-037MSDOI Listing
August 2006

Interferon gamma polymorphisms and their interaction with smoking are associated with lung function.

Authors:
Jian-Qing He Kelly Burkett John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Hum Genet 2006 May 11;119(4):365-75. Epub 2006 Feb 11.

The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s00439-006-0143-zDOI Listing
May 2006

Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study.

Authors:
Alison M Wallace Jian-Qing He Kelly M Burkett Jian Ruan John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Respir Res 2006 May 15;7:76. Epub 2006 May 15.

James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1186/1465-9921-7-76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523340PMC
May 2006

Lack of association of human leukocyte antigen-B7 with COPD and rate of decline in lung function.

Authors:
Ikuma Kasuga Jian Ruan John E Connett Nicholas R Anthonisen Andrew J Sandford

Respir Med 2005 Dec 26;99(12):1528-33. Epub 2005 Apr 26.

The James Hogg iCAPTURE Centre, University of British Columbia, St Paul's Hospital, 1081 Burrard Street, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.rmed.2005.03.021DOI Listing
December 2005

Genetic modifiers of lung disease in cystic fibrosis.

Authors:
Mitchell L Drumm Michael W Konstan Mark D Schluchter Allison Handler Rhonda Pace Fei Zou Maimoona Zariwala David Fargo Airong Xu John M Dunn Rebecca J Darrah Ruslan Dorfman Andrew J Sandford Mary Corey Julian Zielenski Peter Durie Katrina Goddard James R Yankaskas Fred A Wright Michael R Knowles

N Engl J Med 2005 Oct;353(14):1443-53

Department of Pediatrics, Case Western Reserve University, Cleveland, USA.

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http://dx.doi.org/10.1056/NEJMoa051469DOI Listing
October 2005

Selection of reference genes for gene expression studies in human neutrophils by real-time PCR.

Authors:
Xiaozhu Zhang Lily Ding Andrew J Sandford

BMC Mol Biol 2005 Feb 18;6. Epub 2005 Feb 18.

The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St, Paul's Hospital, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1186/1471-2199-6-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551605PMC
February 2005

Reconcilable differences: a cross-sectional study of the relationship between socioeconomic status and the magnitude of short-acting beta-agonist use in asthma.

Authors:
Larry D Lynd Andrew J Sandford Erin M Kelly Peter D Paré Tony R Bai J Mark Fitzgerald Aslam H Anis

Chest 2004 Oct;126(4):1161-8

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S001236921531292
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http://dx.doi.org/10.1378/chest.126.4.1161DOI Listing
October 2004

Therapeutic response to asthma medications: genotype predictors.

Authors:
Alison M Wallace Andrew J Sandford

Treat Respir Med 2004 ;3(3):161-71

University of British Columbia, James Hogg iCapture Centre, St Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.2165/00151829-200403030-00004DOI Listing
September 2004

Glutathione S-transferase variants and their interaction with smoking on lung function.

Authors:
Jian-Qing He John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Am J Respir Crit Care Med 2004 Aug 7;170(4):388-94. Epub 2004 Jun 7.

The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St. Paul's Hospital, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada.

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http://dx.doi.org/10.1164/rccm.200312-1763OCDOI Listing
August 2004

Alpha 1-antitrypsin deficiency alleles in cystic fibrosis lung disease.

Authors:
Despina D Frangolias Jian Ruan Pearce J Wilcox A George F Davidson Lawrence T K Wong Yves Berthiaume Rosamund Hennessey Andreas Freitag Linda Pedder Mary Corey Neil Sweezey Julian Zielenski Elizabeth Tullis Andrew J Sandford

Am J Respir Cell Mol Biol 2003 Sep 14;29(3 Pt 1):390-6. Epub 2003 Apr 14.

McDonald Research Laboratories/iCAPTURE Centre, Division of Biochemical Diseases, Department of Pediatrics, University of British Columbia, B.C. Children's Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1165/rcmb.2002-0271OCDOI Listing
September 2003

Genetic polymorphisms of matrix metalloproteinases: functional importance in the development of chronic obstructive pulmonary disease?

Authors:
Alison M Wallace Andrew J Sandford

Am J Pharmacogenomics 2002 ;2(3):167-75

University of British Columbia McDonald Research Laboratories/iCAPTURE Centre, St Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada.

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http://dx.doi.org/10.2165/00129785-200202030-00002DOI Listing
March 2003

Polymorphisms in the IL13, IL13RA1, and IL4RA genes and rate of decline in lung function in smokers.

Authors:
Jian-Qing He John E Connett Nicholas R Anthonisen Andrew J Sandford

Am J Respir Cell Mol Biol 2003 Mar;28(3):379-85

UBC McDonald Research Laboratories/iCAPTURE Center, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1165/rcmb.4885DOI Listing
March 2003

Polymorphisms of the GM-CSF genes and the development of atopic diseases in at-risk children.

Authors:
Jian-Qing He Jian Ruan Moira Chan-Yeung Allan B Becker Helen Dimich-Ward Peter D Paré Andrew J Sandford

Chest 2003 Mar;123(3 Suppl):438S

UBC McDonald Research Laboratories/iCAPTURE Center, St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1378/chest.123.3_suppl.438sDOI Listing
March 2003

Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers.

Authors:
Jian-Qing He Jian Ruan John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Am J Respir Crit Care Med 2002 Aug;166(3):323-8

UBC McDonald Research Laboratories/iCAPTURE Center, St. Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia, V6Z 1Y6 Canada.

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http://dx.doi.org/10.1164/rccm.2111059DOI Listing
August 2002

Genetic risk factors for chronic obstructive pulmonary disease.

Authors:
Andrew J Sandford Ladina Joos Peter D Paré

Curr Opin Pulm Med 2002 Mar;8(2):87-94

University of British Columbia Pulmonary Research Laboratories/iCAPTURE Center, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/00063198-200203000-00002DOI Listing
March 2002

The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function.

Authors:
Ladina Joos Jian-Qing He Megan B Shepherdson John E Connett Nicholas R Anthonisen Peter D Paré Andrew J Sandford

Hum Mol Genet 2002 Mar;11(5):569-76

University of British Columbia McDonald Research Laboratories/iCAPTURE Center, St Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada.

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http://dx.doi.org/10.1093/hmg/11.5.569DOI Listing
March 2002

Genotype predictors of response to asthma medications.

Authors:
Ladina Joos Andrew J Sandford

Curr Opin Pulm Med 2002 Jan;8(1):9-15

Pulmonary Cell Research Laboratory, Research Department, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1097/00063198-200201000-00003DOI Listing
January 2002

Genetic risk factors of chronic obstructive pulmonary disease.

Authors:
Ladina Joos Peter D Paré Andrew J Sandford

Swiss Med Wkly 2002 Jan;132(3-4):27-37

Departement Innere Medizin, Kantonsspital Basel, Switzerland.

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http://dx.doi.org/2002/03/smw-09752DOI Listing
January 2002