Publications by authors named "Andrew J Pollard"

100Publications

Safety and immunogenicity of a two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Europe (EBOVAC2): a randomised, observer-blind, participant-blind, placebo-controlled, phase 2 trial.

Lancet Infect Dis 2020 Nov 17. Epub 2020 Nov 17.

University Bordeaux, INSERM, Bordeaux Population Health Research Center, UMR 1219, INSERM, CHU Bordeaux, Bordeaux, France; CIC, EUCLID/F-CRIN Clinical Trials Platform, F-33000, Bordeaux, France; Inria SISTM team, F-33405, Talence, France. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(20)30476-XDOI Listing
November 2020

Nanoscale characterization of plasma functionalized graphitic flakes using tip-enhanced Raman spectroscopy.

J Chem Phys 2020 Nov;153(18):184708

National Physical Laboratory, Hampton Road, Teddington TW11 0LW, United Kingdom.

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http://dx.doi.org/10.1063/5.0024370DOI Listing
November 2020

ChAdOx1 nCoV-19 vaccine for SARS-CoV-2 - Authors' reply.

Lancet 2020 11;396(10261):1486-1487

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LE, UK; National Institute of Health Research, Oxford Biomedical Research Centre, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)32267-4DOI Listing
November 2020

What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2.

Lancet Infect Dis 2020 Oct 27. Epub 2020 Oct 27.

Oxford Vaccine Group, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1016/S1473-3099(20)30773-8DOI Listing
October 2020

Integrated Wafer Scale Growth of Single Crystal Metal Films and High Quality Graphene.

ACS Nano 2020 Oct 1;14(10):13593-13601. Epub 2020 Oct 1.

Department of Engineering, University of Cambridge, 9 JJ Thomson Avenue, Cambridge CB3 0FA, United Kingdom.

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http://dx.doi.org/10.1021/acsnano.0c05685DOI Listing
October 2020

Group B Streptococcal disease in England (1998 - 2017): a population based observational study.

Clin Infect Dis 2020 Sep 29. Epub 2020 Sep 29.

Unit of Health-Care Epidemiology, Big Data Institute, Nuffield Department of Population Health, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1093/cid/ciaa1485DOI Listing
September 2020

Payment in challenge studies: ethics, attitudes and a new payment for risk model.

J Med Ethics 2020 Sep 25. Epub 2020 Sep 25.

Department of Experimental Psychology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/medethics-2020-106438DOI Listing
September 2020

What time interval is needed between the administration of live attenuated vaccines?

Arch Dis Child 2020 Dec 8;105(12):1232-1235. Epub 2020 Sep 8.

Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/archdischild-2020-320091DOI Listing
December 2020

Biomarkers for Disease Severity in Children Infected With Respiratory Syncytial Virus: A Systematic Literature Review.

J Infect Dis 2020 Oct;222(Supplement_7):S648-S657

Infectious Diseases Translational Biomarkers, Janssen Pharmaceutica, Beerse, Belgium.

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http://dx.doi.org/10.1093/infdis/jiaa208DOI Listing
October 2020

Elimination of typhoid: Possibility or pipe dream?

J Paediatr Child Health 2020 09 7;56(9):1340-1342. Epub 2020 Aug 7.

NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.

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http://dx.doi.org/10.1111/jpc.15088DOI Listing
September 2020

TIPICO X: report of the 10th interactive infectious disease workshop on infectious diseases and vaccines.

Hum Vaccin Immunother 2020 Aug 5:1-14. Epub 2020 Aug 5.

Translational Paediatrics and Infectious Diseases, Department of Paediatrics, Hospital Clínico Universitario De Santiago De Compostela , Santiago De Compostela, Spain.

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http://dx.doi.org/10.1080/21645515.2020.1788301DOI Listing
August 2020

Early Insights From Clinical Trials of Typhoid Conjugate Vaccine.

Clin Infect Dis 2020 Jul;71(Supplement_2):S155-S159

Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

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http://dx.doi.org/10.1093/cid/ciaa370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388715PMC
July 2020

Why the elderly appear to be more severely affected by COVID-19: The potential role of immunosenescence and CMV.

Rev Med Virol 2020 09 15;30(5):e2144. Epub 2020 Jul 15.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1002/rmv.2144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404358PMC
September 2020

Herd immunity and vaccination of children for COVID-19.

Int J Infect Dis 2020 09 23;98:14-15. Epub 2020 Jun 23.

Institute of Tropical Medicine, Universitätsklinikum Tübingen, Germany; Centre de Recherches Medicales de Lambarene, Gabon.

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http://dx.doi.org/10.1016/j.ijid.2020.06.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308740PMC
September 2020

Third human challenge trial conference, Oxford, United Kingdom, February 6-7, 2020, a meeting report.

Biologicals 2020 Jul 4;66:41-52. Epub 2020 Jun 4.

International Alliance for Biological Standardization, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.biologicals.2020.04.004DOI Listing
July 2020

Immunogenicity and Reactogenicity of a Reduced Schedule of a 4-component Capsular Group B Meningococcal Vaccine: A Randomized Controlled Trial in Infants.

Open Forum Infect Dis 2020 May 29;7(5):ofaa143. Epub 2020 Apr 29.

Oxford Vaccine Group, Department of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.

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http://dx.doi.org/10.1093/ofid/ofaa143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252280PMC
May 2020

Vaccination against Respiratory Syncytial Virus.

Interdiscip Top Gerontol Geriatr 2020 9;43:182-192. Epub 2020 Apr 9.

Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford, Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1159/000504477DOI Listing
September 2020

Progress in the overall understanding of typhoid fever: implications for vaccine development.

Expert Rev Vaccines 2020 04 17;19(4):367-382. Epub 2020 Apr 17.

Oxford Vaccine Group, Department of Pediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre , Oxford, UK.

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http://dx.doi.org/10.1080/14760584.2020.1750375DOI Listing
April 2020

Low Sensitivity of BinaxNOW RSV in Infants.

J Infect Dis 2020 Oct;222(Supplement_7):S640-S647

Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1093/infdis/jiaa050DOI Listing
October 2020

Vaccine communication in a digital society.

Nat Mater 2020 04;19(4):476

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41563-020-0626-7DOI Listing
April 2020

Priorities for developing respiratory syncytial virus vaccines in different target populations.

Sci Transl Med 2020 Mar;12(535)

Oxford Vaccine Group, Department of Paediatrics and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7LE, UK.

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http://dx.doi.org/10.1126/scitranslmed.aax2466DOI Listing
March 2020

The science of vaccine safety: Summary of meeting at Wellcome Trust.

Vaccine 2020 02 24;38(8):1869-1880. Epub 2020 Jan 24.

Kaiser Permanente Colorado, Institute for Health Research, Colorado School of Public Health, Department of Epidemiology, USA.

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http://dx.doi.org/10.1016/j.vaccine.2020.01.024DOI Listing
February 2020

A Novel, Heterozygous Three Base-Pair Deletion in CARD11 Results in B Cell Expansion with NF-κB and T Cell Anergy Disease.

J Clin Immunol 2020 02 2;40(2):406-411. Epub 2020 Jan 2.

Department of Clinical Immunology, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1007/s10875-019-00729-xDOI Listing
February 2020

Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA).

Cochrane Database Syst Rev 2019 12 30;12:CD008669. Epub 2019 Dec 30.

University Medical Center Utrecht, Utrecht University, Julius Center for Health Sciences and Primary Care & Department of Otorhinolaryngology, Heidelberglaan 100, Utrecht, Netherlands, 3508 GA.

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http://dx.doi.org/10.1002/14651858.CD008669.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953364PMC
December 2019

Antibody-Dependent Natural Killer Cell Activation after Ebola Vaccination.

J Infect Dis 2019 Dec 10. Epub 2019 Dec 10.

Department of Infection Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, U.K.

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http://dx.doi.org/10.1093/infdis/jiz657DOI Listing
December 2019

Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal.

N Engl J Med 2019 12;381(23):2209-2218

From the Oxford University Clinical Research Unit (M.S., S.D., A.K., B. Basnyat), Patan Academy of Health Sciences, Patan Hospital (D.P., M.G., S.S.), the Nepal Family Development Foundation (A.A.), and Wasa Pasa Polyclinics Private, Lalitpur (B. Bajracharya) - all in Kathmandu; the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford (R.C.-J., K.T.-N., M.V., N.S., X.L., S.T., O.M., Y.G.F., J.C., J.H., S.K., A.J.P.), and the Department of Medicine, University of Cambridge, Cambridge (S.B.) - all in the United Kingdom; the Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam (S.B.); and the University of Maryland School of Medicine, Baltimore (K.M.N.).

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http://dx.doi.org/10.1056/NEJMoa1905047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785806PMC
December 2019

Congenital viral infections in England over five decades: a population-based observational study.

Lancet Infect Dis 2020 02 7;20(2):220-229. Epub 2019 Nov 7.

Unit of Health-Care Epidemiology, Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK; National Institute for Health Research Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1016/S1473-3099(19)30416-5DOI Listing
February 2020

Persistent circulation of a fluoroquinolone-resistant Salmonella enterica Typhi clone in the Indian subcontinent.

J Antimicrob Chemother 2020 02;75(2):337-341

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, OX3 7LE, UK.

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http://dx.doi.org/10.1093/jac/dkz435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223262PMC
February 2020

Typhoid-From Past to Future.

Clin Infect Dis 2019 10;69(Suppl 5):S375-S376

Oxford Vaccine Group/Oxford Martin School, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/cid/ciz551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792103PMC
October 2019

Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its outer membrane vesicle component.

Sci Rep 2019 09 24;9(1):13797. Epub 2019 Sep 24.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.1038/s41598-019-50310-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760121PMC
September 2019

Outcomes beyond hospital discharge in infants and children with viral meningitis: A systematic review.

Rev Med Virol 2020 Mar 16;30(2):e2083. Epub 2019 Sep 16.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/rmv.2083
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http://dx.doi.org/10.1002/rmv.2083DOI Listing
March 2020

Bone and joint infections in Oxford: a 10-year retrospective review.

Arch Dis Child 2020 05 28;105(5):515-516. Epub 2019 Aug 28.

Department of Paediatrics, University of Oxford, Children's Hospital, Oxford, UK

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http://dx.doi.org/10.1136/archdischild-2019-317992DOI Listing
May 2020

Two centuries of immunisation in the UK (part II).

Arch Dis Child 2020 03 13;105(3):216-222. Epub 2019 Jul 13.

Paediatrics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/archdischild-2019-317707DOI Listing
March 2020

Epigenetics in Sepsis: Understanding Its Role in Endothelial Dysfunction, Immunosuppression, and Potential Therapeutics.

Front Immunol 2019 18;10:1363. Epub 2019 Jun 18.

Oxford Vaccine Group, Department of Paediatrics, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.01363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591469PMC
October 2020

Two centuries of immunisation in the UK (part 1).

Arch Dis Child 2020 02 4;105(2):115-121. Epub 2019 Jul 4.

Department of Paediatrics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/archdischild-2019-317314DOI Listing
February 2020

Classical and Non-classical Presentations of Complement Factor I Deficiency: Two Contrasting Cases Diagnosed via Genetic and Genomic Methods.

Front Immunol 2019 7;10:1150. Epub 2019 Jun 7.

Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.01150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568211PMC
November 2020

A systematic review of antimicrobial resistance of typhoidal in India.

Indian J Med Res 2019 02;149(2):151-163

Department of Paediatrics, University of Oxford & NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.4103/ijmr.IJMR_830_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563740PMC
February 2019

Introduction.

Pediatr Infect Dis J 2019 06;38(6S Suppl 1):S1

Division of Infectious Diseases, Nationwide Children's Hospital, Columbus, Ohio.

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http://dx.doi.org/10.1097/INF.0000000000002316DOI Listing
June 2019

Common Genetic Variations Associated with the Persistence of Immunity following Childhood Immunization.

Cell Rep 2019 06;27(11):3241-3253.e4

Department of Paediatrics, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1016/j.celrep.2019.05.053DOI Listing
June 2019

Cost-effectiveness of routine and campaign use of typhoid Vi-conjugate vaccine in Gavi-eligible countries: a modelling study.

Lancet Infect Dis 2019 07 23;19(7):728-739. Epub 2019 May 23.

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30804-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595249PMC
July 2019

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study.

Vaccine 2019 06 14;37(26):3485-3494. Epub 2019 May 14.

Tropical Diseases, Murdoch Children's Research Institute, Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Victoria, Australia; Infectious Diseases Unit, Department of General Medicine, The Royal Children's Hospital Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.vaccine.2019.03.059DOI Listing
June 2019

Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis.

Sci Rep 2019 05 2;9(1):6843. Epub 2019 May 2.

Lydia Becker Institute of Immunology and Inflammation, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1038/s41598-019-43139-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497663PMC
May 2019

Nanoscale chemical imaging using tip-enhanced Raman spectroscopy.

Nat Protoc 2019 04 25;14(4):1169-1193. Epub 2019 Mar 25.

National Physical Laboratory, Teddington, UK.

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http://www.nature.com/articles/s41596-019-0132-z
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http://dx.doi.org/10.1038/s41596-019-0132-zDOI Listing
April 2019

Accelerating Typhoid Conjugate Vaccine Introduction: What Can Be Learned From Prior New Vaccine Introduction Initiatives?

Clin Infect Dis 2019 03;68(Suppl 2):S171-S176

Center for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1093/cid/ciy1118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405264PMC
March 2019

The Time is Now to Control Typhoid.

Clin Infect Dis 2019 03;68(Suppl 2):S47-S49

Center for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1093/cid/ciy1115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405270PMC
March 2019

The Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines.

Clin Infect Dis 2019 03;68(Suppl 2):S183-S190

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/cid/ciy1119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405265PMC
March 2019

A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales.

Pediatr Infect Dis J 2019 07;38(7):673-677

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom.

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http://dx.doi.org/10.1097/INF.0000000000002280DOI Listing
July 2019

Strategies to improve detection and management of human parechovirus infection in young infants.

Lancet Infect Dis 2019 02 12;19(2):e51-e58. Epub 2018 Oct 12.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK; Vaccine Evaluation Center, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S14733099183028
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http://dx.doi.org/10.1016/S1473-3099(18)30288-3DOI Listing
February 2019

Epidemiology and Immune Pathogenesis of Viral Sepsis.

Front Immunol 2018 27;9:2147. Epub 2018 Sep 27.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02147
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http://dx.doi.org/10.3389/fimmu.2018.02147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170629PMC
October 2019

Antibodies in lymphocyte supernatants can distinguish between neutralising antibodies induced by RSV vaccination and pre-existing antibodies induced by natural infection.

Vaccine 2018 11 11;36(46):6988-6994. Epub 2018 Oct 11.

Oxford Vaccine Group, Department of Paediatrics, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7LE,UK; KEMRI-Wellcome Trust Research Programme, Bofa Road, Kilifi, Kenya. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2018.09.070DOI Listing
November 2018

A systematic review of antimicrobial resistance in Salmonella enterica serovar Typhi, the etiological agent of typhoid.

PLoS Negl Trop Dis 2018 10 11;12(10):e0006779. Epub 2018 Oct 11.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.

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http://dx.plos.org/10.1371/journal.pntd.0006779
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http://dx.doi.org/10.1371/journal.pntd.0006779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198998PMC
October 2018