Publications by authors named "Andrew J Dannenberg"

100Publications

Docked SARS CoV-2 Proteins within the Cutaneous and Subcutaneous Microvasculature and their Role in the Pathogenesis of Severe COVID-19.

Hum Pathol 2020 Oct 12. Epub 2020 Oct 12.

Ohio State University Comprehensive Cancer Center and Discovery Life Sciences, Columbus, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2020.10.002DOI Listing
October 2020

Improvement in Insulin Resistance and Estimated Hepatic Steatosis and Fibrosis after Endoscopic Sleeve Gastroplasty.

Gastrointest Endosc 2020 Aug 27. Epub 2020 Aug 27.

Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York-Presbyterian Hospital, New York. Electronic address:

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http://dx.doi.org/10.1016/j.gie.2020.08.023DOI Listing
August 2020

Obesity is Associated with Worse Outcomes in COVID-19: Analysis of Early Data from New York City.

Obesity (Silver Spring) 2020 09;28(9):1606-1612

Division of Gastroenterology and Hepatology, New York-Presbyterian Hospital and Weill Cornell Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1002/oby.22923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283831PMC
September 2020

Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.

Am J Pathol 2019 10 16;189(10):2019-2035. Epub 2019 Jul 16.

Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York; Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880774PMC
October 2019

Accounting for Height in an Analysis of Body Fat and Breast Cancer Risk-In Reply.

JAMA Oncol 2019 07;5(7):1068

Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2019.1103DOI Listing
July 2019

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

Immunity 2019 05 23;50(5):1232-1248.e14. Epub 2019 Apr 23.

Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Sigmund-Freud-Str. 27, 53127 Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193013
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http://dx.doi.org/10.1016/j.immuni.2019.03.014DOI Listing
May 2019

The obese adipose tissue microenvironment in cancer development and progression.

Nat Rev Endocrinol 2019 03;15(3):139-154

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1038/s41574-018-0126-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374176PMC
March 2019

Pioglitazone Inhibits Periprostatic White Adipose Tissue Inflammation in Obese Mice.

Cancer Prev Res (Phila) 2018 04 8;11(4):215-226. Epub 2017 Dec 8.

Department of Medicine, Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1158/1940-6207.CAPR-17-0296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882568PMC
April 2018

Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation.

J Clin Oncol 2016 12 7;34(35):4270-4276. Epub 2016 Nov 7.

Neil M. Iyengar, Ayca Gucalp, and Clifford A. Hudis, Memorial Sloan Kettering Cancer Center; Neil M. Iyengar, Ayca Gucalp, Andrew J. Dannenberg, and Clifford A. Hudis, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.67.4283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562428PMC
December 2016

Sleep and Breathing … and Cancer?

Cancer Prev Res (Phila) 2016 11 7;9(11):821-827. Epub 2016 Sep 7.

Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, California.

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http://dx.doi.org/10.1158/1940-6207.CAPR-16-0092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353979PMC
November 2016

Obesity-induced lymphatic dysfunction is reversible with weight loss.

J Physiol 2016 12 9;594(23):7073-7087. Epub 2016 Oct 9.

The Department of Surgery, Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.

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http://dx.doi.org/10.1113/JP273061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134379PMC
December 2016

Metabolic Dysfunction, Obesity, and Survival Among Patients With Early-Stage Colorectal Cancer.

J Clin Oncol 2016 Oct;34(30):3664-3671

Elizabeth M. Cespedes Feliciano, Candyce H. Kroenke, Marilyn L. Kwan, Charles Quesenberry, Erin K. Weltzien, Adrienne L. Castillo, and Bette J. Caan, Kaiser Permanente Northern California, Oakland; Patrick T. Bradshaw, School of Public Health, University of California, Berkeley, Berkeley, CA; Jeffrey A. Meyerhardt, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Carla M. Prado and Jingjie Xiao, University of Alberta, Edmonton, Alberta, Canada; and Andrew J. Dannenberg, Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1200/JCO.2016.67.4473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065112PMC
October 2016

Adipose-Resident Group 1 Innate Lymphoid Cells Promote Obesity-Associated Insulin Resistance.

Immunity 2016 08 2;45(2):428-41. Epub 2016 Aug 2.

Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004886PMC
August 2016

Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.

J Biol Chem 2016 07 1;291(31):16011-23. Epub 2016 Jun 1.

From the Department of Medicine, Weill Cornell Medical College, New York, New York 10065.

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http://dx.doi.org/10.1074/jbc.M115.698902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965552PMC
July 2016

Cox-2-derived PGE2 induces Id1-dependent radiation resistance and self-renewal in experimental glioblastoma.

Neuro Oncol 2016 10 28;18(10):1379-89. Epub 2016 Mar 28.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York (P.J.C., R.T., R.B.); Department of Molecular Biology, Weill Cornell Graduate School of Medical Sciences of Cornell University, New York, New York (R.T.); Departments of Biochemistry, Chemistry, and Pharmacology, A.B. Hancock Jr. Memorial Laboratory for Cancer Research, Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, Tennessee (P.J.K., L.J.M.); Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York (F.S., V.S.T); Department of Medicine, Weill Cornell Medical College, New York, (D.C.M, A.J.D.)

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http://dx.doi.org/10.1093/neuonc/now049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035519PMC
October 2016

Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression.

Semin Oncol 2016 Feb 8;43(1):154-160. Epub 2015 Sep 8.

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789163PMC
February 2016

Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1.

Proc Natl Acad Sci U S A 2015 Dec 14;112(52):16000-5. Epub 2015 Dec 14.

Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, NY 10065; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1507294112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703007PMC
December 2015

Leptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells.

Cancer Prev Res (Phila) 2015 Dec 20;8(12):1174-83. Epub 2015 Oct 20.

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan. Department of Internal Medicine Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan. VA Medical Center, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670788PMC
December 2015

Id1 expression in endothelial cells of the colon is required for normal response to injury.

Am J Pathol 2015 Nov 5;185(11):2983-93. Epub 2015 Sep 5.

Department of Medicine, Weill Cornell Medical College, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630175PMC
November 2015

Obesity and cancer: local and systemic mechanisms.

Annu Rev Med 2015 ;66:297-309

Memorial Sloan Kettering Cancer Center, New York, NY 10065; email: ,

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http://www.annualreviews.org/doi/10.1146/annurev-med-050913-
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http://dx.doi.org/10.1146/annurev-med-050913-022228DOI Listing
September 2015

ID1 is a functional marker for intestinal stem and progenitor cells required for normal response to injury.

Stem Cell Reports 2014 Nov 23;3(5):716-24. Epub 2014 Oct 23.

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235234PMC
November 2014

Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance.

Cancer Prev Res (Phila) 2014 Aug 16;7(8):805-12. Epub 2014 May 16.

Division of Hematology and Oncology, Departments of Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine; University Hospitals Case Medical Center, Cleveland, Ohio;

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125515PMC
August 2014

p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.

Cancer Prev Res (Phila) 2014 Jun 15;7(6):596-606. Epub 2014 Apr 15.

Authors' Affiliations: Department of Medicine, Weill Cornell Medical College; Department of Basic Sciences, College of Dentistry; and Department of Environmental Medicine, School of Medicine, New York University, New York; Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland; and Department of Medical and Molecular Genetics, Indiana University Simon Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074578PMC
June 2014

p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.

J Biol Chem 2014 Mar 22;289(10):6513-25. Epub 2014 Jan 22.

From the Department of Medicine, Weill Cornell Medical College, New York, New York 10065.

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http://dx.doi.org/10.1074/jbc.M113.532523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945316PMC
March 2014

Tobacco smoke-induced immunologic changes may contribute to oral carcinogenesis.

J Investig Med 2014 Feb;62(2):316-23

From the Departments of *Dermatology and †Medicine, Weill Cornell Medical College, New York, NY ‡Department of Surgery (Head and Neck Service), Memorial Sloan-Kettering Cancer Center, New York, NY; §Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD; and ∥Department of Public Health, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.2310/JIM.0000000000000031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902110PMC
February 2014

IL-6-mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages.

J Immunol 2014 Jan 27;192(1):349-57. Epub 2013 Nov 27.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065;

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http://dx.doi.org/10.4049/jimmunol.1301906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872272PMC
January 2014

Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer.

Clin Cancer Res 2013 Nov 19;19(22):6074-83. Epub 2013 Aug 19.

Authors' Affiliations: Departments of Cell & Developmental Biology and Medicine, Weill Cornell Medical College; and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891839PMC
November 2013

Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice.

Cancer Prev Res (Phila) 2013 Sep 23;6(9):886-97. Epub 2013 Jul 23.

Department of Medicine, Weill Cornell Medical College, 525 East 68th St, Room F-206, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767430PMC
September 2013

Obesity and inflammation: new insights into breast cancer development and progression.

Am Soc Clin Oncol Educ Book 2013 :46-51

From the Memorial Sloan-Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.14694/EdBook_AM.2013.33.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897299PMC
November 2015

Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers.

Cancer Prev Res (Phila) 2013 Jul 16;6(7):646-55. Epub 2013 May 16.

Department of Surgery (Head and Neck Service), Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707304PMC
July 2013

Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.

Prostaglandins Other Lipid Mediat 2013 Oct 25;106:99-105. Epub 2013 Apr 25.

Department of Cell & Developmental Biology and Weill Cornell Cancer Center, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10988823130002
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http://dx.doi.org/10.1016/j.prostaglandins.2013.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830707PMC
October 2013

Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study.

Front Immunol 2013 18;4:67. Epub 2013 Mar 18.

Department of Biomedical Sciences, Baker Institute for Animal Health, Cornell University Ithaca, NY, USA.

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http://dx.doi.org/10.3389/fimmu.2013.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600535PMC
March 2013

Sphingolipid signaling in metabolic disorders.

Cell Metab 2012 Oct 13;16(4):420-34. Epub 2012 Sep 13.

Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cmet.2012.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466368PMC
October 2012

Breast cancer risk reduction: no pain, no gain?

J Clin Oncol 2012 Oct 27;30(28):3436-8. Epub 2012 Aug 27.

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http://dx.doi.org/10.1200/JCO.2012.44.8597DOI Listing
October 2012

A web-based screening and accrual strategy for a cancer prevention clinical trial in healthy smokers.

Contemp Clin Trials 2012 Sep 5;33(5):942-8. Epub 2012 Jul 5.

Department of Surgery (Head and Neck Service), Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15517144120017
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http://dx.doi.org/10.1016/j.cct.2012.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460548PMC
September 2012

Comparing decision making between cancer patients and the general population: thoughts, emotions, or social influence?

J Health Commun 2012 29;17(4):477-94. Epub 2012 Feb 29.

Department of Communication, State University of New York at Buffalo, Buffalo, New York 14260, USA.

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http://dx.doi.org/10.1080/10810730.2011.635774DOI Listing
August 2012

Matrix metalloproteinase-dependent microsomal prostaglandin E synthase-1 expression in macrophages: role of TNF-α and the EP4 prostanoid receptor.

J Immunol 2012 Feb 6;188(4):1970-80. Epub 2012 Jan 6.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.4049/jimmunol.1102383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273587PMC
February 2012

The effect of HIV and HPV coinfection on cervical COX-2 expression and systemic prostaglandin E2 levels.

Cancer Prev Res (Phila) 2012 Jan 1;5(1):34-40. Epub 2011 Dec 1.

Division of Infectious Diseases, Center for Global Health, Weill Cornell Medical College, 440 East 69 Street, New York, NY, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252428PMC
January 2012

Macrophages induce COX-2 expression in breast cancer cells: role of IL-1β autoamplification.

Carcinogenesis 2011 May 10;32(5):695-702. Epub 2011 Feb 10.

Department of Medicine and Weill Cornell Cancer Center,Weill Cornell Medical College, New York, NY 10021, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgr027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086701PMC
May 2011

The prostaglandin transporter regulates adipogenesis and aromatase transcription.

Cancer Prev Res (Phila) 2011 Feb 6;4(2):194-206. Epub 2011 Jan 6.

Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://cancerpreventionresearch.aacrjournals.org/content/ear
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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
Publisher Site
http://dx.doi.org/10.1158/1940-6207.CAPR-10-0367DOI Listing
February 2011