Andrew Hemphill

Andrew Hemphill

UNVERIFIED PROFILE

Are you Andrew Hemphill?   Register this Author

Register author
Andrew Hemphill

Andrew Hemphill

Publications by authors named "Andrew Hemphill"

Are you Andrew Hemphill?   Register this Author

100Publications

1163Reads

45Profile Views

In vitro treatment of Besnoitia besnoiti with the naphto-quinone buparvaquone results in marked inhibition of tachyzoite proliferation, mitochondrial alterations and rapid adaptation of tachyzoites to increased drug concentrations.

Parasitology 2019 Jan 20;146(1):112-120. Epub 2018 Jun 20.

Institute of Parasitology,Vetsuisse Faculty,University of Berne,Länggass-Strasse 122,CH-3012 Berne,Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182018000975DOI Listing
January 2019

Immunization with a cocktail of antigens fused with OprI reduces Neospora caninum vertical transmission and postnatal mortality in mice.

Vaccine 2019 Jan 27;37(3):473-483. Epub 2018 Nov 27.

Institute for Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2018.11.060DOI Listing
January 2019

Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis.

Int J Parasitol Drugs Drug Resist 2018 12 31;8(3):440-450. Epub 2018 Oct 31.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3012, Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22113207183012
Publisher Site
http://dx.doi.org/10.1016/j.ijpddr.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216040PMC
December 2018

Repurposing of commercially available anti-coccidials identifies diclazuril and decoquinate as potential therapeutic candidates against Besnoitia besnoiti infection.

Vet Parasitol 2018 Sep 31;261:77-85. Epub 2018 Aug 31.

SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03044017183030
Publisher Site
http://dx.doi.org/10.1016/j.vetpar.2018.08.015DOI Listing
September 2018

Physiological aspects of nitro drug resistance in Giardia lamblia.

Int J Parasitol Drugs Drug Resist 2018 08 28;8(2):271-277. Epub 2018 Apr 28.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggass-Strasse 122, CH-3012 Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2018.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039359PMC
August 2018

Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis.

Int J Parasitol Drugs Drug Resist 2018 08 15;8(2):331-340. Epub 2018 Jun 15.

Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3012, Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020078PMC
August 2018

First Characterization of the Dense Granule Protein GRA9.

Biomed Res Int 2017 12;2017:6746437. Epub 2017 Nov 12.

Institute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University, Düsseldorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/6746437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702412PMC
July 2018

Evaluation of kinase-inhibitors nilotinib and everolimus against alveolar echinococcosis in vitro and in a mouse model.

Exp Parasitol 2018 May 3;188:65-72. Epub 2018 Apr 3.

Institute of Parasitology, Vetsuisse Faculty, University of Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00144894173057
Publisher Site
http://dx.doi.org/10.1016/j.exppara.2018.04.002DOI Listing
May 2018

Modulation of cis- and trans- Golgi and the Rab9A-GTPase during infection by Besnoitia besnoiti, Toxoplasma gondii and Neospora caninum.

Exp Parasitol 2018 Apr 27;187:75-85. Epub 2018 Feb 27.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, Bern, 3012, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2018.02.008DOI Listing
April 2018

TbLpn, a key enzyme in lipid droplet formation and phospholipid metabolism, is essential for mitochondrial integrity and growth of Trypanosoma brucei.

Mol Microbiol 2018 Apr 21. Epub 2018 Apr 21.

Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.13976DOI Listing
April 2018

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities.

ChemMedChem 2017 12 6;12(24):2094-2098. Epub 2017 Dec 6.

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cmdc.201700600DOI Listing
December 2017

In vitro screening of the open source Pathogen Box identifies novel compounds with profound activities against Neospora caninum.

Int J Parasitol 2017 10 25;47(12):801-809. Epub 2017 Jul 25.

Institute for Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.06.002DOI Listing
October 2017

In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites.

Int J Parasitol 2017 10 9;47(12):811-821. Epub 2017 Sep 9.

SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.08.005DOI Listing
October 2017

Neospora caninum in non-pregnant and pregnant mouse models: cross-talk between infection and immunity.

Int J Parasitol 2017 10 10;47(12):723-735. Epub 2017 Sep 10.

Institute for Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.09.001DOI Listing
October 2017

ApiCOWplexa 2017 - 4th International Meeting on Apicomplexan Parasites in Farm Animals.

Int J Parasitol 2017 10;47(12):697-699

Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria 3800, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2017.09.002DOI Listing
October 2017

Extended-spectrum antiprotozoal bumped kinase inhibitors: A review.

Exp Parasitol 2017 Sep 5;180:71-83. Epub 2017 Jan 5.

Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Reemerging Infectious Diseases (CERID), University of Washington, Seattle, WA 98109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498274PMC
September 2017

Development of a movement-based in vitro screening assay for the identification of new anti-cestodal compounds.

PLoS Negl Trop Dis 2017 May 17;11(5):e0005618. Epub 2017 May 17.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0005618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448807PMC
May 2017

In vitro activity of gentamicin as an adjunct to penicillin against biofilm group B Streptococcus.

J Antimicrob Chemother 2017 02 20;72(2):444-447. Epub 2016 Dec 20.

Institute for Infectious Diseases, University of Bern, Bern, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkw447DOI Listing
February 2017

Elucidating the influence of praziquantel nanosuspensions on the in vivo metabolism of Taenia crassiceps cysticerci.

Acta Trop 2016 Sep 4;161:100-5. Epub 2016 Jun 4.

Tropical Pathology and Public Health Institute, 235 street, Federal University of Goias, Goiania, CEP: 74605-050, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actatropica.2016.06.002DOI Listing
September 2016

Drug target identification in protozoan parasites.

Expert Opin Drug Discov 2016 Aug 16;11(8):815-24. Epub 2016 Jun 16.

a Institute of Parasitology, Vetsuisse Faculty , University of Bern , Bern , Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17460441.2016.1195945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983455PMC
August 2016

Apicomplexans pulling the strings: manipulation of the host cell cytoskeleton dynamics.

Parasitology 2016 07 4;143(8):957-70. Epub 2016 Apr 4.

Centro de Investigação Interdisciplinar em Sanidade Animal,Faculdade de Medicina Veterinária,Universidade de Lisboa, Avenida da Universidade Técnica,1300-477 Lisboa,Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182016000524DOI Listing
July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

N-terminal fusion of a toll-like receptor 2-ligand to a Neospora caninum chimeric antigen efficiently modifies the properties of the specific immune response.

Parasitology 2016 Apr 2;143(5):606-16. Epub 2016 Mar 2.

Institute for Parasitology,Vetsuisse Faculty,University of Berne,Länggass-Strasse 122,CH-3012 Bern,Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182016000056DOI Listing
April 2016

Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models.

Parasitology 2016 Mar 2;143(3):245-59. Epub 2015 Dec 2.

Institute of Parasitology, University of Berne,Berne,Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182015001596DOI Listing
March 2016

Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis.

PLoS Negl Trop Dis 2016 Mar 11;10(3):e0004535. Epub 2016 Mar 11.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0004535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788259PMC
March 2016

Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.

Vet Res 2016 Feb 17;47:32. Epub 2016 Feb 17.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, 3012, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13567-016-0317-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756515PMC
February 2016

Characterization of the Neospora caninum NcROP40 and NcROP2Fam-1 rhoptry proteins during the tachyzoite lytic cycle.

Parasitology 2016 Jan 2;143(1):97-113. Epub 2015 Nov 2.

SALUVET,Animal Health Department,Faculty of Veterinary Sciences,Complutense University of Madrid,Ciudad Universitaria s/n,28040-Madrid,Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182015001511DOI Listing
January 2016

Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin.

Int J Antimicrob Agents 2015 Nov 2;46(5):546-51. Epub 2015 Sep 2.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, CH-3012 Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijantimicag.2015.07.016DOI Listing
November 2015

Susceptibility versus resistance in alveolar echinococcosis (larval infection with Echinococcus multilocularis).

Vet Parasitol 2015 Oct 31;213(3-4):103-9. Epub 2015 Jul 31.

Institute of Parasitology, Vetsuisse Faculty and Faculty of Medicine, University of Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2015.07.029DOI Listing
October 2015

Treatment of echinococcosis: albendazole and mebendazole--what else?

Parasite 2014 22;21:70. Epub 2014 Dec 22.

Vetsuisse Faculty, Institute of Parasitology, University of Berne, Länggass-Strasse 122, 3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/parasite/2014073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271654PMC
September 2015

In vitro effects of new artemisinin derivatives in Neospora caninum-infected human fibroblasts.

Int J Antimicrob Agents 2015 Jul 14;46(1):88-93. Epub 2015 Apr 14.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijantimicag.2015.02.020DOI Listing
July 2015

Dose-dependent effects of experimental infection with the virulent Neospora caninum Nc-Spain7 isolate in a pregnant mouse model.

Vet Parasitol 2015 Jul 5;211(3-4):133-40. Epub 2015 Jun 5.

Institute of Parasitology, Vetsuisse Faculty, University of Bern, CH-3012 Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2015.05.021DOI Listing
July 2015

Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice.

Int J Parasitol Drugs Drug Resist 2015 Apr 13;5(1):16-25. Epub 2015 Feb 13.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, Bern 3012, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412913PMC
April 2015

A live vaccine against Neospora caninum abortions in cattle.

Vaccine 2015 Mar 7;33(11):1299-301. Epub 2015 Feb 7.

School of Medical and Molecular Biosciences, University of Technology, PO Box 123, Broadway, Sydney 2007, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2015.01.064DOI Listing
March 2015

A vaccine formulation combining rhoptry proteins NcROP40 and NcROP2 improves pup survival in a pregnant mouse model of neosporosis.

Vet Parasitol 2015 Jan 25;207(3-4):203-15. Epub 2014 Dec 25.

SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2014.12.009DOI Listing
January 2015

A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts.

Int J Parasitol Drugs Drug Resist 2014 Dec 19;4(3):201-9. Epub 2014 Sep 19.

Institute for Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, 3012 Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266814PMC
December 2014

A review on bovine besnoitiosis: a disease with economic impact in herd health management, caused by Besnoitia besnoiti (Franco and Borges, ).

Parasitology 2014 Sep 2;141(11):1406-17. Epub 2014 Apr 2.

Institute of Parasitology, Vetsuisse Faculty,University of Bern,Länggass-Strasse 122, CH-3012 Bern,Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182014000262DOI Listing
September 2014

ApiCOWplexa 2013--2nd International Meeting on Apicomplexan Parasites in Farm Animals.

Parasitology 2014 Sep;141(11):1355-8

CVZ, CIISA Faculdade de Medicina Veterinária, Instituto de Investigação Científica Tropical,Universidade de Lisboa,Avenida Universidade Técnica, 1300-447 Lisboa,Portugal.

View Article

Download full-text PDF

Source
https://www.cambridge.org/core/product/identifier/S003118201
Publisher Site
http://dx.doi.org/10.1017/S0031182014001164DOI Listing
September 2014

Phenotypic and molecular characterization of hyperpigmented group B Streptococci.

Int J Med Microbiol 2014 Jul 16;304(5-6):717-24. Epub 2014 May 16.

Institute for Infectious Diseases, University of Bern, Bern, Switzerland; Department of Infectious Diseases, Bern University Hospital, Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijmm.2014.05.003DOI Listing
July 2014

Vaccines against neosporosis: what can we learn from the past studies?

Exp Parasitol 2014 May 3;140:52-70. Epub 2014 Mar 3.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2014.02.015DOI Listing
May 2014

Activities of fenbendazole in comparison with albendazole against Echinococcus multilocularis metacestodes in vitro and in a murine infection model.

Int J Antimicrob Agents 2014 Apr 12;43(4):335-42. Epub 2014 Feb 12.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggassstrasse 122, CH-3012 Berne, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijantimicag.2014.01.013DOI Listing
April 2014

Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes.

Int J Antimicrob Agents 2014 Jan 23;43(1):40-6. Epub 2013 Oct 23.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggassstrasse 122, CH-3012 Berne, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijantimicag.2013.09.012DOI Listing
January 2014

Subcutaneous infection model facilitates treatment assessment of secondary Alveolar echinococcosis in mice.

PLoS Negl Trop Dis 2013 23;7(5):e2235. Epub 2013 May 23.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0002235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662659PMC
November 2013

In vitro effects of novel ruthenium complexes in Neospora caninum and Toxoplasma gondii tachyzoites.

Antimicrob Agents Chemother 2013 Nov 26;57(11):5747-54. Epub 2013 Aug 26.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02446-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811262PMC
November 2013

New approaches for the identification of drug targets in protozoan parasites.

Int Rev Cell Mol Biol 2013 ;301:359-401

Institute of Parasitology, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-407704-1.00007-5DOI Listing
September 2013

In vitro and in vivo activities of dicationic diguanidino compounds against Echinococcus multilocularis metacestodes.

Antimicrob Agents Chemother 2013 Aug 28;57(8):3829-35. Epub 2013 May 28.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02569-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719769PMC
August 2013

Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model.

Pathogens 2013 Mar 27;2(2):193-208. Epub 2013 Mar 27.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/pathogens2020193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235717PMC
March 2013

In vitro culture systems for the study of apicomplexan parasites in farm animals.

Int J Parasitol 2013 Feb 21;43(2):115-24. Epub 2012 Sep 21.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2012.08.004DOI Listing
February 2013

Proteins mediating the Neospora caninum-host cell interaction as targets for vaccination.

Front Biosci (Elite Ed) 2013 Jan 1;5:23-36. Epub 2013 Jan 1.

Vetsuisse Faculty, Institute of Parasitology, University of Berne, Langgass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
January 2013

Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice.

Int J Parasitol Drugs Drug Resist 2012 Dec 2;2:109-20. Epub 2012 Apr 2.

Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Berne, Länggassstrasse 122, CH-3012 Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2012.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862485PMC
December 2012

Development of a high- versus low-pathogenicity model of the free-living amoeba Naegleria fowleri.

Microbiology 2012 Oct 9;158(Pt 10):2652-60. Epub 2012 Aug 9.

Biology Division, Spiez Laboratory, Federal Office for Civil Protection, Austrasse, CH-3700 Spiez, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/mic.0.059790-0DOI Listing
October 2012

Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection.

Vaccine 2012 Oct 29;30(46):6588-94. Epub 2012 Aug 29.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2012.08.024DOI Listing
October 2012

Effects of miltefosine treatment in fibroblast cell cultures and in mice experimentally infected with Neospora caninum tachyzoites.

Parasitology 2012 Jun 6;139(7):934-44. Epub 2012 Feb 6.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182012000066DOI Listing
June 2012

Intra-cisternal vaccination induces high-level protection against Neospora caninum infection in mice.

Vaccine 2012 Jun 23;30(28):4209-15. Epub 2012 Apr 23.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2012.04.050DOI Listing
June 2012

A new promising application for highly cytotoxic metal compounds: η6-areneruthenium(II) phosphite complexes for the treatment of alveolar echinococcosis.

J Med Chem 2012 May 20;55(9):4178-88. Epub 2012 Apr 20.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm300291aDOI Listing
May 2012

Voluntary ingestion of antiparasitic drugs emulsified in honey represents an alternative to gavage in mice.

J Am Assoc Lab Anim Sci 2012 Mar;51(2):219-23

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314525PMC
March 2012

Drug target identification in intracellular and extracellular protozoan parasites.

Curr Top Med Chem 2011 ;11(16):2029-38

Institute of Parasitology, University of Berne, Länggass-Strasse, Switzerland.

View Article

Download full-text PDF

Source
December 2011

Besnoitia besnoiti protein disulfide isomerase (BbPDI): molecular characterization, expression and in silico modelling.

Exp Parasitol 2011 Oct 3;129(2):164-74. Epub 2011 Jul 3.

Instituto de Investigação Cientifica Tropical, CIISA, Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Av. da Universidade Técnica, 1300-477 Lisboa, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2011.06.012DOI Listing
October 2011

In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes.

Antimicrob Agents Chemother 2011 Oct 18;55(10):4866-72. Epub 2011 Jul 18.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Langgass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00478-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186988PMC
October 2011

Experimental treatment of Neospora caninum-infected mice with the arylimidamide DB750 and the thiazolide nitazoxanide.

Exp Parasitol 2011 Oct 22;129(2):95-100. Epub 2011 Jul 22.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2011.07.010DOI Listing
October 2011

Vaccines against a Major Cause of Abortion in Cattle, Neospora caninum Infection.

Animals (Basel) 2011 Sep 8;1(3):306-25. Epub 2011 Sep 8.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ani1030306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513463PMC
September 2011

RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection.

Vaccine 2011 Sep 23;29(40):6967-75. Epub 2011 Jul 23.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2011.07.038DOI Listing
September 2011

Identification of a host cell target for the thiazolide class of broad-spectrum anti-parasitic drugs.

Exp Parasitol 2011 Jun 16;128(2):145-50. Epub 2011 Feb 16.

Institute of Parasitology, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2011.02.007DOI Listing
June 2011

In vitro and in vivo efficacies of mefloquine-based treatment against alveolar echinococcosis.

Antimicrob Agents Chemother 2011 Feb 6;55(2):713-21. Epub 2010 Dec 6.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01392-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028781PMC
February 2011

Echinococcus multilocularis: the impact of ionizing radiation on metacestodes.

Exp Parasitol 2011 Jan 16;127(1):127-34. Epub 2010 Jul 16.

Institute of Radiation-Oncology, University of Duesseldorf, D-40225 Duesseldorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2010.07.006DOI Listing
January 2011

Intraperitoneal Echinococcus multilocularis infection in mice modulates peritoneal CD4+ and CD8+ regulatory T cell development.

Parasitol Int 2011 Jan 20;60(1):45-53. Epub 2010 Oct 20.

Institute of Parasitology, University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S138357691000153
Publisher Site
http://dx.doi.org/10.1016/j.parint.2010.10.002DOI Listing
January 2011

Echinococcus multilocularis phosphoglucose isomerase (EmPGI): a glycolytic enzyme involved in metacestode growth and parasite-host cell interactions.

Int J Parasitol 2010 Nov 30;40(13):1563-74. Epub 2010 Jun 30.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2010.05.009DOI Listing
November 2010

Molecular characterization of Neospora caninum MAG1, a dense granule protein secreted into the parasitophorous vacuole, and associated with the cyst wall and the cyst matrix.

Parasitology 2010 Sep 6;137(11):1605-19. Epub 2010 May 6.

Institute of Veterinary Pharmacology and Toxicology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 124, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182010000442DOI Listing
September 2010

Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes.

J Antimicrob Chemother 2010 Mar 19;65(3):512-9. Epub 2010 Jan 19.

Institute of Parasitology, Vetsuisse Faculty, University of Berne, Länggass-Strasse 122, CH-3012 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkp490DOI Listing
March 2010