Andrew H A Clayton

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Andrew H A Clayton

Publications by authors named "Andrew H A Clayton"

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55Publications

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Exploring oligomeric state of the serotonin receptor utilizing photobleaching image correlation spectroscopy: implications for receptor function.

Faraday Discuss 2018 Apr 23;207:409-421. Epub 2018 Jan 23.

CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500 007, India.

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April 2018

Antimicrobial peptides: biochemical determinants of activity and biophysical techniques of elucidating their functionality.

World J Microbiol Biotechnol 2018 Apr 12;34(4):62. Epub 2018 Apr 12.

Faculty of Science, Engineering and Technology, Swinburne University of Technology, John Street, P. O. Box 218, Hawthorn, VIC, 3122, Australia.

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April 2018

A pH-induced conformational switch in a tyrosine kinase inhibitor identified by electronic spectroscopy and quantum chemical calculations.

Sci Rep 2017 Nov 24;7(1):16271. Epub 2017 Nov 24.

Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria, 3122, Australia.

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November 2017

Revealing the sequence of interactions of PuroA peptide with Candida albicans cells by live-cell imaging.

Sci Rep 2017 Mar 2;7:43542. Epub 2017 Mar 2.

Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, PO Box 218, Hawthorn, VIC, Australia.

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March 2017

Solvatochromism and linear solvation energy relationship of the kinase inhibitor SKF86002.

Spectrochim Acta A Mol Biomol Spectrosc 2017 Jan 17;170:226-33. Epub 2016 Jul 17.

Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria 3122, Australia. Electronic address:

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January 2017

Imaging Cellular Dynamics with Spectral Relaxation Imaging Microscopy: Distinct Spectral Dynamics in Golgi Membranes of Living Cells.

Sci Rep 2016 11 22;6:37038. Epub 2016 Nov 22.

Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria, Australia.

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November 2016

Interactions of a lytic peptide with supported lipid bilayers investigated by time-resolved evanescent wave-induced fluorescence spectroscopy.

Methods Appl Fluoresc 2016 Sep 28;4(4):044001. Epub 2016 Sep 28.

School of Chemistry, University of Melbourne, 3010 Victoria, Australia.

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September 2016

UV-Vis spectroscopy and solvatochromism of the tyrosine kinase inhibitor AG-1478.

Spectrochim Acta A Mol Biomol Spectrosc 2016 07 12;164:128-32. Epub 2016 Apr 12.

Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria 3122, Australia. Electronic address:

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July 2016

Anti-biofilm and sporicidal activity of peptides based on wheat puroindoline and barley hordoindoline proteins.

J Pept Sci 2016 Jul 30;22(7):492-500. Epub 2016 May 30.

Faculty of Science, Engineering and Technology, Swinburne University of Technology, PO Box 218, John Street, Hawthorn, VIC, 3122, Australia.

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July 2016

Direct Measurement of Pore Dynamics and Leakage Induced by a Model Antimicrobial Peptide in Single Vesicles and Cells.

Langmuir 2016 06 17;32(25):6496-505. Epub 2016 Jun 17.

Faculty of Science, Engineering and Technology, Swinburne University of Technology , Hawthorn, Victoria 3122, Australia.

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June 2016

Analysis of complex anisotropy decays from single-frequency polarized-phasor ellipse plots.

Methods Appl Fluoresc 2016 May 23;4(2):024005. Epub 2016 May 23.

Cell Biophysics Laboratory, Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Victoria 3122, Australia.

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May 2016

BioNetFit: a fitting tool compatible with BioNetGen, NFsim and distributed computing environments.

Bioinformatics 2016 03 9;32(5):798-800. Epub 2015 Nov 9.

Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ, USA.

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March 2016

Spatiotemporal Control of Transmembrane Proteins through the Cytoskeleton: An Evolving Story.

Biophys J 2016 Mar;110(5):1036-7

CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India. Electronic address:

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March 2016

Archetypal tryptophan-rich antimicrobial peptides: properties and applications.

World J Microbiol Biotechnol 2016 Feb 9;32(2):31. Epub 2016 Jan 9.

Faculty of Science, Engineering and Technology, Swinburne University of Technology, PO Box 218, Hawthorn, VIC, 3122, Australia.

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February 2016

SpIDA Surveys the Intricate Web of Macromolecular Oligomerization In Situ.

Biophys J 2015 Aug;109(4):663-4

Centre for Microphotonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria, Australia. Electronic address:

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August 2015

Get your kICS by measuring membrane protein dynamics.

Biophys J 2015 Jul;109(1):1-2

Council of Scientific and Industrial Research, Centre for Cellular and Molecular Biology, Hyderabad, India. Electronic address:

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July 2015

Inhibiting EGFR clustering and cell proliferation with gold nanoparticles.

Small 2015 Apr 12;11(14):1638-43. Epub 2014 Dec 12.

Centre for Micro-Photonics, Faculty of Engineering, Science and Technology, Swinburne University of Technology, Hawthorn, PO Box 218, Victoria, 3122, Australia.

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April 2015

The transition from single molecule to ensemble revealed by fluorescence polarization.

Sci Rep 2015 Feb 2;5:8158. Epub 2015 Feb 2.

Centre for Micro-Photonics, School of Science, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia.

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February 2015

Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation.

Int J Nanomedicine 2013 19;8:2601-11. Epub 2013 Jul 19.

Centre for Micro-Photonics and Industrial Research Institute Swinburne, Faculty of Engineering and Industrial Sciences Swinburne University of Technology, Hawthorn, VIC, Australia.

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April 2014

Recruitment of the adaptor protein Grb2 to EGFR tetramers.

Biochemistry 2014 Apr 21;53(16):2594-604. Epub 2014 Apr 21.

Centre for Micro-Photonics, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology , Hawthorn, Victoria 3122, Australia.

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April 2014

Taking care of bystander FRET in a crowded cell membrane environment.

Biophys J 2014 Mar;106(6):1227-8

CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India. Electronic address:

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March 2014

Long-time-scale interaction dynamics between a model antimicrobial peptide and giant unilamellar vesicles.

Langmuir 2013 Nov 14;29(47):14613-21. Epub 2013 Nov 14.

School of Chemistry and ‡Florey Department of Neuroscience and Mental Health, Centre for Neuroscience Research Chemistry, University of Melbourne , Parkville, Victoria 3010, Australia.

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November 2013

The effect of translational motion on FLIM measurements-single particle phasor-FLIM.

J Fluoresc 2013 Jul 8;23(4):671-9. Epub 2013 Mar 8.

Centre for Micro-photonics, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, John Street, PO Box 218, Hawthorn, Victoria, 3122, Australia.

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July 2013

Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.

Mol Biosyst 2013 Jul 30;9(7):1849-63. Epub 2013 Apr 30.

Centre for Micro-Photonics, Faculty of Engineering and Industrial Sciences, Cell Biophysics Laboratory, Swinburne University of Technology, PO Box 218, Hawthorn, Victoria 3122, Australia.

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July 2013

A toolbox of fluorescence microscopic approaches reveals dynamics and assembly of a membrane-associated protein.

Biophys J 2013 May;104(9):1844-5

Centre for Microphotonics, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, Hawthorn, Victoria, Australia.

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May 2013

Aggregation distributions on cells determined by photobleaching image correlation spectroscopy.

Biophys J 2013 Mar;104(5):1056-64

Department of Pathology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Australia.

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March 2013

Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy.

Cancer Res 2012 Jun 1;72(12):2924-30. Epub 2012 Jun 1.

Joint Austin-Ludwig Medical Oncology Unit, Austin Hospital, Australia.

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June 2012

Slow insertion kinetics during interaction of a model antimicrobial peptide with unilamellar phospholipid vesicles.

Langmuir 2012 Jan 22;28(4):2217-24. Epub 2011 Dec 22.

School of Chemistry, University of Melbourne, Parkville, Victoria 3010, Australia.

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January 2012

Evidence for extended YFP-EGFR dimers in the absence of ligand on the surface of living cells.

Phys Biol 2011 Dec 26;8(6):066002. Epub 2011 Sep 26.

Centre for Microphotonics, Swinburne University of Technology, Victoria, Australia.

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December 2011

Conformational dynamics in a truncated epidermal growth factor receptor ectodomain.

Biochemistry 2011 Jun 18;50(23):5130-9. Epub 2011 May 18.

Swinburne University of Technology , Victoria 3122, Australia.

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June 2011

Differential and synergistic effects of epidermal growth factor receptor antibodies on unliganded ErbB dimers and oligomers.

Biochemistry 2011 May 15;50(18):3581-90. Epub 2011 Apr 15.

Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Royal Melbourne Hospital, Victoria 3050, Australia.

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May 2011

Fixation alters fluorescence lifetime and anisotropy of cells expressing EYFP-tagged serotonin1A receptor.

Biochem Biophys Res Commun 2011 Feb 8;405(2):234-7. Epub 2011 Jan 8.

Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500 007, India.

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February 2011

Creation and biophysical characterization of a high-affinity, monomeric EGF receptor ectodomain using fluorescent proteins.

Biochemistry 2010 Sep;49(35):7459-66

Ludwig Institute for Cancer Research, P.O. Box 2008, Royal Melbourne Hospital, Victoria 3050, Australia.

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September 2010

Profilin interaction with phosphatidylinositol (4,5)-bisphosphate destabilizes the membrane of giant unilamellar vesicles.

Biophys J 2009 Jun;96(12):5112-21

Centre for Bioactive Discovery in Health and Ageing, School of Science and Technology, University of New England, Armidale, Australia.

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June 2009

The preparation of colloidally stable, water-soluble, biocompatible, semiconductor nanocrystals with a small hydrodynamic diameter.

ACS Nano 2009 May;3(5):1121-8

School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, VIC 3010, Australia.

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May 2009

Predominance of activated EGFR higher-order oligomers on the cell surface.

Growth Factors 2008 Dec;26(6):316-24

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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December 2008

Experimental determination of quantum dot size distributions, ligand packing densities, and bioconjugation using analytical ultracentrifugation.

Nano Lett 2008 Sep 30;8(9):2883-90. Epub 2008 Jul 30.

School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

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September 2008

Enumeration of oligomerization states of membrane proteins in living cells by homo-FRET spectroscopy and microscopy: theory and application.

Biophys J 2007 May;92(9):3098-104

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637616.

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May 2007

Unligated epidermal growth factor receptor forms higher order oligomers within microclusters on A431 cells that are sensitive to tyrosine kinase inhibitor binding.

Biochemistry 2007 Apr 24;46(15):4589-97. Epub 2007 Mar 24.

The Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, P.O. Box 2008, Royal Melbourne Hospital, Victoria 3050, Australia.

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April 2007

Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.

J Biol Chem 2005 Aug 30;280(34):30392-9. Epub 2005 Jun 30.

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Victoria 3050, Australia.

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August 2005

Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal.

Mol Endocrinol 2005 Jul 3;19(7):1884-92. Epub 2005 Mar 3.

Prince Henry's Institute of Medical Research, Level 4 Block E, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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July 2005

Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin.

Anal Biochem 2005 Jul;342(2):292-9

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, P.O. Royal Melbourne Hospital, Parkville, Vic. 3050, Australia.

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July 2005

Dual-channel photobleaching FRET microscopy for improved resolution of protein association states in living cells.

Eur Biophys J 2005 Feb 30;34(1):82-90. Epub 2004 Jun 30.

Ludwig Institute for Cancer Research, Royal Melbourne Hospital, P.O. Box 2008, 3050 Parkville, Victoria , Australia.

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February 2005

Photophysics of green and red fluorescent proteins: implications for quantitative microscopy.

Methods Enzymol 2003 ;360:178-201

Advanced Science and Technology Laboratory, AstraZeneca Research and Development Charnwood, Loughborough, United Kingdom.

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May 2003

Unfolding of class A amphipathic peptides on a lipid surface.

Biochemistry 2003 Feb;42(6):1747-53

Russell Grimwade School of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, Victoria, Australia.

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February 2003

Dynamic fluorescence anisotropy imaging microscopy in the frequency domain (rFLIM).

Biophys J 2002 Sep;83(3):1631-49

Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany.

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September 2002

Site-specific tryptophan fluorescence spectroscopy as a probe of membrane peptide structure and dynamics.

Eur Biophys J 2002 Mar;31(1):9-13

The Russell Grimwade School of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia.

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March 2002