Andrew Grimson

Andrew Grimson

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Andrew Grimson

Andrew Grimson

Publications by authors named "Andrew Grimson"

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38Publications

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Evolutionary dynamics of microRNA target sites across vertebrate evolution.

PLoS Genet 2020 Feb 3;16(2):e1008285. Epub 2020 Feb 3.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018135PMC
February 2020

CDK2 kinase activity is a regulator of male germ cell fate.

Development 2019 Nov 6;146(21). Epub 2019 Nov 6.

Cornell University, College of Veterinary Medicine, Department of Biomedical Sciences, Ithaca, NY 14853, USA

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http://dx.doi.org/10.1242/dev.180273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857589PMC
November 2019

The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation.

J Exp Med 2019 Jun 11;216(6):1268-1279. Epub 2019 Apr 11.

Baker Institute for Animal Health and Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY

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http://dx.doi.org/10.1084/jem.20180131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547860PMC
June 2019

Characterizing mRNA Sequence Motifs in the 3'-UTR Using GFP Reporter Constructs.

Methods Mol Biol 2018 ;1720:77-88

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-7540-2_6DOI Listing
July 2018

Developmental Origin Governs CD8 T Cell Fate Decisions during Infection.

Cell 2018 06 14;174(1):117-130.e14. Epub 2018 Jun 14.

Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183064
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http://dx.doi.org/10.1016/j.cell.2018.05.029DOI Listing
June 2018

Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis.

RNA Biol 2017 02 16;14(2):219-235. Epub 2016 Dec 16.

a Department of Molecular Biology and Genetics , Cornell University , Ithaca , NY , USA.

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http://dx.doi.org/10.1080/15476286.2016.1270002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324742PMC
February 2017

Integrated network analysis reveals distinct regulatory roles of transcription factors and microRNAs.

RNA 2016 11 7;22(11):1663-1672. Epub 2016 Sep 7.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1261/rna.048025.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066619PMC
November 2016

A position-specific 3'UTR sequence that accelerates mRNA decay.

RNA Biol 2016 Nov 26;13(11):1075-1077. Epub 2016 Aug 26.

a Department of Molecular Biology and Genetics , Cornell University , Ithaca , NY , USA.

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http://dx.doi.org/10.1080/15476286.2016.1225645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100352PMC
November 2016

The roles of microRNAs and siRNAs in mammalian spermatogenesis.

Development 2016 09;143(17):3061-73

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047671PMC
http://dx.doi.org/10.1242/dev.136721DOI Listing
September 2016

A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1.

Genes Dev 2016 05;30(9):1070-85

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA;

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http://dx.doi.org/10.1101/gad.277392.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863738PMC
May 2016

High-throughput discovery of post-transcriptional cis-regulatory elements.

BMC Genomics 2016 Mar 3;17:177. Epub 2016 Mar 3.

Department of Molecular Biology and Genetics, Cornell University, 445 Biotech, Ithaca, NY, 14853, USA.

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http://dx.doi.org/10.1186/s12864-016-2479-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778349PMC
March 2016

A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.

Cell 2016 Jan;164(1-2):310-323

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715267PMC
January 2016

MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells.

Genetics 2015 Nov 28;201(3):1017-30. Epub 2015 Sep 28.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853

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http://dx.doi.org/10.1534/genetics.115.179176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649632PMC
November 2015

miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells.

Sci Rep 2015 Nov 9;5:16399. Epub 2015 Nov 9.

Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853.

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http://dx.doi.org/10.1038/srep16399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637875PMC
November 2015

Widespread alternative and aberrant splicing revealed by lariat sequencing.

Nucleic Acids Res 2015 Sep 10;43(17):8488-501. Epub 2015 Aug 10.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA

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http://nar.oxfordjournals.org/content/43/17/8488.full.pdf
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkv763
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http://dx.doi.org/10.1093/nar/gkv763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787815PMC
September 2015

Systematic analysis of the Hmga2 3' UTR identifies many independent regulatory sequences and a novel interaction between distal sites.

RNA 2015 Jul 21;21(7):1346-60. Epub 2015 May 21.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA

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http://dx.doi.org/10.1261/rna.051177.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478353PMC
July 2015

Noncoding RNA: linking microRNAs to their targets.

Authors:
Andrew Grimson

Nat Chem Biol 2015 Feb;11(2):100-1

Department of Molecular Biology &Genetics, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1038/nchembio.1741DOI Listing
February 2015

Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life.

J Immunol 2014 Jul 21;193(1):177-84. Epub 2014 May 21.

Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853;

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http://dx.doi.org/10.4049/jimmunol.1400553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065808PMC
July 2014

Dissecting disease inheritance modes in a three-dimensional protein network challenges the "guilt-by-association" principle.

Am J Hum Genet 2013 Jul 20;93(1):78-89. Epub 2013 Jun 20.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1016/j.ajhg.2013.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710751PMC
July 2013

AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline.

Dev Cell 2012 Aug 2;23(2):251-64. Epub 2012 Aug 2.

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1016/j.devcel.2012.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470808PMC
August 2012

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs.

Nat Struct Mol Biol 2011 Sep 11;18(10):1139-46. Epub 2011 Sep 11.

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nsmb.2115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190056PMC
September 2011

A targeted approach to miRNA target identification.

Authors:
Andrew Grimson

Nat Methods 2010 Oct 29;7(10):795-7. Epub 2010 Sep 29.

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http://dx.doi.org/10.1038/nmeth1010-795DOI Listing
October 2010

Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals.

Nature 2008 Oct 1;455(7217):1193-7. Epub 2008 Oct 1.

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature07415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837422PMC
October 2008

Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons.

Mol Cell Biol 2007 Aug 11;27(16):5630-8. Epub 2007 Jun 11.

Department of Genetics, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/MCB.00410-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952128PMC
August 2007

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution.

Science 2005 Dec 24;310(5755):1817-21. Epub 2005 Nov 24.

Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, and Howard Hughes Medical Institute, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1126/science.1121158DOI Listing
December 2005

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.

Nature 2005 Feb 30;433(7027):769-73. Epub 2005 Jan 30.

Rosetta Inpharmatics, Merck and Co, 401 Terry Avenue N, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1038/nature03315DOI Listing
February 2005

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Mol Cell 2003 Nov;12(5):1187-200

Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236-0004, Japan.

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http://dx.doi.org/10.1016/s1097-2765(03)00443-xDOI Listing
November 2003

SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A.

EMBO J 2003 Feb;22(3):641-50

Department of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1093/emboj/cdg056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140740PMC
February 2003