Andrew G Ewing

Andrew G Ewing

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Andrew G Ewing

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Imaging Mass Spectrometry Shows That Zinc Deficiency Leads to Lipids Changes in Drosophila Brain Similar to Cognitive Impairing Drugs.

Chembiochem 2020 May 13. Epub 2020 May 13.

Chalmers Institute of Technology, Chemical and Biological Engineering, Kemivägen 10, 41296, Göteborg, SWEDEN.

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http://dx.doi.org/10.1002/cbic.202000197DOI Listing
May 2020

Intracellular Electrochemical Nanomeasurements Reveal that Exocytosis of Molecules at Living Neurons is Subquantal and Complex.

Angew Chem Int Ed Engl 2020 Apr 3;59(17):6711-6714. Epub 2020 Mar 3.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 412 96, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/anie.201914564DOI Listing
April 2020

Interplay between Cocaine, Drug Removal, and Methylphenidate Reversal on Phospholipid Alterations in Brain Determined by Imaging Mass Spectrometry.

ACS Chem Neurosci 2020 Mar 21;11(5):806-813. Epub 2020 Feb 21.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.

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http://dx.doi.org/10.1021/acschemneuro.0c00014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077924PMC
March 2020

Simultaneous Quantification of Vesicle Size and Catecholamine Content by Resistive Pulses in Nanopores and Vesicle Impact Electrochemical Cytometry.

J Am Chem Soc 2020 Mar 24;142(9):4093-4097. Epub 2020 Feb 24.

Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/jacs.9b13221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108759PMC
March 2020

Amperometric Measurements and Dynamic Models Reveal a Mechanism for How Zinc Alters Neurotransmitter Release.

Angew Chem Int Ed Engl 2020 Feb 6;59(8):3083-3087. Epub 2020 Feb 6.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/anie.201913184DOI Listing
February 2020

Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD) Brain.

ACS Chem Neurosci 2020 01 12;11(1):14-24. Epub 2019 Dec 12.

Department of Chemistry and Molecular Biology , University of Gothenburg , Gothenburg 405 30 , Sweden.

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http://dx.doi.org/10.1021/acschemneuro.9b00532DOI Listing
January 2020

Plasticity in exocytosis revealed through the effects of repetitive stimuli affect the content of nanometer vesicles and the fraction of transmitter released.

Proc Natl Acad Sci U S A 2019 10 30;116(43):21409-21415. Epub 2019 Sep 30.

Department of Chemistry and Molecular Biology, University of Gothenburg, 412 96 Gothenburg, Sweden

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http://dx.doi.org/10.1073/pnas.1910859116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815131PMC
October 2019

Dopamine Release Dynamics in the Tuberoinfundibular Dopamine System.

J Neurosci 2019 May 19;39(21):4009-4022. Epub 2019 Feb 19.

Department of Neuroscience, Karolinska Institutet, 17165 Stockholm, Sweden,

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http://dx.doi.org/10.1523/JNEUROSCI.2339-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529860PMC
May 2019

Extracellular ATP Regulates the Vesicular Pore Opening in Chromaffin Cells and Increases the Fraction Released During Individual Exocytosis Events.

ACS Chem Neurosci 2019 05 1;10(5):2459-2466. Epub 2019 Apr 1.

Department of Chemistry and Molecular Biology , University of Gothenburg , Kemivägen 10 , 41296 Gothenburg , Sweden.

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http://dx.doi.org/10.1021/acschemneuro.8b00722DOI Listing
May 2019

Altered Lipid Composition of Secretory Cells Following Exposure to Zinc Can Be Correlated to Changes in Exocytosis.

Chemistry 2019 Apr 13;25(21):5406-5411. Epub 2019 Mar 13.

Chemical Imaging Infrastructure, CII, University of Gothenburg and Chalmers University of Technology, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://doi.wiley.com/10.1002/chem.201900010
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http://dx.doi.org/10.1002/chem.201900010DOI Listing
April 2019

Anticancer Drug Tamoxifen Affects Catecholamine Transmitter Release and Storage from Single Cells.

ACS Chem Neurosci 2019 04 26;10(4):2060-2069. Epub 2019 Feb 26.

Department of Chemistry and Molecular Biology , University of Gothenburg , SE-412 96 Gothenburg , Sweden.

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http://dx.doi.org/10.1021/acschemneuro.8b00714DOI Listing
April 2019

Combined Amperometry and Electrochemical Cytometry Reveal Differential Effects of Cocaine and Methylphenidate on Exocytosis and the Fraction of Chemical Release.

Angew Chem Int Ed Engl 2019 03 18;58(13):4238-4242. Epub 2019 Feb 18.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/anie.201813717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519382PMC
March 2019

Chemical Analysis of Single Cells.

Anal Chem 2019 01 12;91(1):588-621. Epub 2018 Dec 12.

University of Gothenburg , Department of Chemistry and Molecular Biology , Gothenburg 41296 , Sweden.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b04732
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http://dx.doi.org/10.1021/acs.analchem.8b04732DOI Listing
January 2019

Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS.

J Lipid Res 2018 11 11;59(11):2098-2107. Epub 2018 Sep 11.

Department of Chemistry and Chemical Engineering, University of Gothenburg, Gothenburg 412 96, Sweden

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http://dx.doi.org/10.1194/jlr.M087734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210908PMC
November 2018

On-Tissue Chemical Derivatization of Catecholamines Using 4-( N-Methyl)pyridinium Boronic Acid for ToF-SIMS and LDI-ToF Mass Spectrometry Imaging.

Anal Chem 2018 11 5;90(22):13580-13590. Epub 2018 Nov 5.

Department of Chemistry and Molecular Biology , University of Gothenburg , Kemivägen 10 , 405 30 Gothenburg , Sweden.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b03746
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http://dx.doi.org/10.1021/acs.analchem.8b03746DOI Listing
November 2018

Electrochemical quantification of transmitter concentration in single nanoscale vesicles isolated from PC12 cells.

Faraday Discuss 2018 10;210(0):353-364

Department of Chemistry and Molecular Biology, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

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http://dx.doi.org/10.1039/c8fd00020dDOI Listing
October 2018

Benefits of NaCl addition for time-of-flight secondary ion mass spectrometry analysis including the discrimination of diacylglyceride and triacylglyceride ions.

Rapid Commun Mass Spectrom 2018 Sep;32(17):1473-1480

Department of Chemistry and Molecular Biology, University of Gothenburg, 412 96, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/rcm.8181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274607PMC
September 2018

Mass Spectrometry Imaging Suggests That Cisplatin Affects Exocytotic Release by Alteration of Cell Membrane Lipids.

Anal Chem 2018 07 6;90(14):8509-8516. Epub 2018 Jul 6.

Department of Chemistry and Molecular Biology , University of Gothenburg , 40530 Gothenburg , Sweden.

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http://dx.doi.org/10.1021/acs.analchem.8b01395DOI Listing
July 2018

Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila Brain.

ACS Chem Neurosci 2018 06 20;9(6):1462-1468. Epub 2018 Mar 20.

Department of Chemistry and Chemical Engineering , Chalmers University of Technology , Gothenburg 412 96 , Sweden.

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http://dx.doi.org/10.1021/acschemneuro.8b00046DOI Listing
June 2018

Nanopore Opening at Flat and Nanotip Conical Electrodes during Vesicle Impact Electrochemical Cytometry.

ACS Nano 2018 03 16;12(3):3010-3019. Epub 2018 Mar 16.

Department of Chemistry and Molecular Biology , University of Gothenburg , Kemivägen 10 , 41296 Gothenburg , Sweden.

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http://dx.doi.org/10.1021/acsnano.8b00781DOI Listing
March 2018

Electrochemical Investigation of the Interaction between Catecholamines and ATP.

Anal Chem 2018 02 22;90(3):1601-1607. Epub 2018 Jan 22.

Unidad de Farmacología, Facultad de Medicina, Universidad de La Laguna , 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.

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http://dx.doi.org/10.1021/acs.analchem.7b02494DOI Listing
February 2018

DMSO Chemically Alters Cell Membranes to Slow Exocytosis and Increase the Fraction of Partial Transmitter Released.

Chembiochem 2017 10 21;18(19):1898-1902. Epub 2017 Aug 21.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/cbic.201700410DOI Listing
October 2017

Mechanistic Aspects of Vesicle Opening during Analysis with Vesicle Impact Electrochemical Cytometry.

Anal Chem 2017 09 22;89(17):9416-9423. Epub 2017 Aug 22.

Department of Chemistry and Molecular Biology, University of Gothenburg , Kemivägen 10, 41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.analchem.7b02226DOI Listing
September 2017

MS/MS analysis and imaging of lipids across Drosophila brain using secondary ion mass spectrometry.

Anal Bioanal Chem 2017 Jun 7;409(16):3923-3932. Epub 2017 Apr 7.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00216-017-0336-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437193PMC
June 2017

Nano Secondary Ion Mass Spectrometry Imaging of Dopamine Distribution Across Nanometer Vesicles.

ACS Nano 2017 04 27;11(4):3446-3455. Epub 2016 Dec 27.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology , Gothenburg SE-412 96, Sweden.

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http://dx.doi.org/10.1021/acsnano.6b07233DOI Listing
April 2017

Zinc Regulates Chemical-Transmitter Storage in Nanometer Vesicles and Exocytosis Dynamics as Measured by Amperometry.

Angew Chem Int Ed Engl 2017 04 20;56(18):4970-4975. Epub 2017 Mar 20.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Kemivägen 10, 412 96, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/anie.201700095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540326PMC
April 2017

On the mechanism of electrochemical vesicle cytometry: chromaffin cell vesicles and liposomes.

Faraday Discuss 2016 12;193:65-79

Chalmers University of Technology, Department of Chemistry and Chemical Engineering, Kemivägen 10, 412 96 Gothenburg, Sweden. and University of Gothenburg, Department of Chemistry and Molecular Biology, Kemivägen 10, 412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1039/c6fd00102eDOI Listing
December 2016

Single cell amperometry reveals curcuminoids modulate the release of neurotransmitters during exocytosis from PC12 cells.

J Electroanal Chem (Lausanne) 2016 Nov 13;781:30-35. Epub 2016 Oct 13.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.jelechem.2016.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450664PMC
November 2016

Quantitative Chemical Measurements of Vesicular Transmitters with Electrochemical Cytometry.

Acc Chem Res 2016 10 13;49(10):2347-2354. Epub 2016 Sep 13.

Department of Chemistry and Molecular Biology, University of Gothenburg , SE-405 30 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.accounts.6b00331DOI Listing
October 2016

Multimodal Imaging of Chemically Fixed Cells in Preparation for NanoSIMS.

Anal Chem 2016 09 9;88(17):8841-8. Epub 2016 Aug 9.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology , SE-412 96, Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.analchem.6b02408DOI Listing
September 2016

Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry.

Anal Bioanal Chem 2016 Sep 22;408(24):6857-68. Epub 2016 Aug 22.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00216-016-9812-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012256PMC
September 2016

Food-induced changes of lipids in rat neuronal tissue visualized by ToF-SIMS imaging.

Sci Rep 2016 09 6;6:32797. Epub 2016 Sep 6.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/srep32797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011716PMC
September 2016

Using Single-Cell Amperometry To Reveal How Cisplatin Treatment Modulates the Release of Catecholamine Transmitters during Exocytosis.

Angew Chem Int Ed Engl 2016 07 30;55(31):9041-4. Epub 2016 May 30.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/anie.201602977DOI Listing
July 2016

Mass spectrometric profiling of lipids in intestinal tissue from rats fed cereals processed for medical conditions.

Biointerphases 2016 Jun 11;11(2):02A310. Epub 2016 Jun 11.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden and National Center for Imaging Mass Spectrometry, Gothenburg 412 96, Sweden.

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http://dx.doi.org/10.1116/1.4939599DOI Listing
June 2016

Laser Desorption Ionization Mass Spectrometry Imaging of Drosophila Brain Using Matrix Sublimation versus Modification with Nanoparticles.

Anal Chem 2016 Feb 12;88(3):1734-41. Epub 2016 Jan 12.

Department of Chemistry and Molecular Biology, University of Gothenburg , Kemivägen 10, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.analchem.5b03942DOI Listing
February 2016

Lithographic Microfabrication of a 16-Electrode Array on a Probe Tip for High Spatial Resolution Electrochemical Localization of Exocytosis.

Anal Chem 2016 Feb 28;88(4):2080-7. Epub 2016 Jan 28.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology , SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.analchem.5b03316DOI Listing
February 2016

The evidence for open and closed exocytosis as the primary release mechanism.

Q Rev Biophys 2016 Jan 18;49:e12. Epub 2016 Jul 18.

Department of Chemistry and Chemical Engineering,Chalmers University of Technology,41296 Gothenburg,Sweden.

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http://dx.doi.org/10.1017/S0033583516000081DOI Listing
January 2016

Electrochemical Measurements of Optogenetically Stimulated Quantal Amine Release from Single Nerve Cell Varicosities in Drosophila Larvae.

Angew Chem Int Ed Engl 2015 Nov 21;54(46):13609-12. Epub 2015 Sep 21.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology Department, Kemivägen 10, 41296 Gothenburg (Sweden).

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http://dx.doi.org/10.1002/anie.201506743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786367PMC
November 2015

Quantitative measurement of transmitters in individual vesicles in the cytoplasm of single cells with nanotip electrodes.

Angew Chem Int Ed Engl 2015 Oct 12;54(41):11978-82. Epub 2015 Aug 12.

Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Kemivägen 10, 41296 Gothenburg (Sweden).

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http://dx.doi.org/10.1002/anie.201504839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747609PMC
October 2015

Spatial neuroproteomics using imaging mass spectrometry.

Biochim Biophys Acta 2015 Jul 9;1854(7):718-31. Epub 2015 Jan 9.

National Center for Imaging Mass Spectrometry, University of Gothenburg and Chalmers University of Technology, Gothenburg, Sweden; Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2014.12.026DOI Listing
July 2015

Characterizing the catecholamine content of single mammalian vesicles by collision-adsorption events at an electrode.

J Am Chem Soc 2015 Apr 31;137(13):4344-6. Epub 2015 Mar 31.

†Department of Chemistry and Chemical Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ja512972fDOI Listing
April 2015

Lipid structural effects of oral administration of methylphenidate in Drosophila brain by secondary ion mass spectrometry imaging.

Anal Chem 2015 Apr 13;87(8):4063-71. Epub 2015 Apr 13.

†Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/acs.analchem.5b00555DOI Listing
April 2015

Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells.

PLoS One 2014 6;9(3):e91132. Epub 2014 Mar 6.

Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania, United States of America; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091132PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946314PMC
February 2015

Probing the lipid chemistry of neurotoxin-induced hippocampal lesions using multimodal imaging mass spectrometry.

Surf Interface Anal 2014 Nov 28;46(Suppl 1):375-378. Epub 2014 Mar 28.

National Center for Imaging Mass Spectrometry, Gothenburg University and Chalmers University of Technology, Sweden.

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http://dx.doi.org/10.1002/sia.5418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558446PMC
November 2014

Analysis of liposome model systems by time-of-flight secondary ion mass spectrometry.

Surf Interface Anal 2014 Nov;46(Suppl 1):74-78

Department of Chemical and Biological Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden ; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1002/sia.5623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408321PMC
November 2014

ToF-SIMS imaging of lipids and lipid related compounds in Drosophila brain.

Surf Interface Anal 2014 Nov;46(Suppl 1):123-126

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, SE-412 96 Gothenburg, Sweden ; National Center Imaging Mass Spectrometry, Kemivägen 10, SE-412 96 Gothenburg, Sweden ; Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1002/sia.5547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408320PMC
November 2014

Development of an organic lateral resolution test device for imaging mass spectrometry.

Anal Chem 2014 Oct 15;86(19):9473-80. Epub 2014 Sep 15.

Department of Chemistry and Molecular Biology, University of Gothenburg , SE-405 30, Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac501228xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188270PMC
October 2014

Simultaneous study of subcellular exocytosis with individually addressable multiple microelectrodes.

Analyst 2014 Jul;139(13):3290-5

Department of Chemistry and Molecular Biology, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1039/c4an00058gDOI Listing
July 2014

High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMS.

ACS Chem Neurosci 2014 Jul 9;5(7):568-75. Epub 2014 May 9.

National Center for Imaging Mass Spectrometry, University of Gothenburg and Chalmers University of Technology, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/cn500039bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102959PMC
July 2014

Spatial elucidation of spinal cord lipid- and metabolite- regulations in amyotrophic lateral sclerosis.

Sci Rep 2014 Jun 12;4:5266. Epub 2014 Jun 12.

1] National Center for Imaging Mass Spectrometry, University of Gothenburg and Chalmers University of Technology, Gothenburg, Sweden [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden [3] Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/srep05266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053717PMC
June 2014

Spatial resolution of single-cell exocytosis by microwell-based individually addressable thin film ultramicroelectrode arrays.

Anal Chem 2014 May 23;86(9):4515-20. Epub 2014 Apr 23.

Department of Chemistry and Molecular Biology, University of Gothenburg , Kemivägen 10, 41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac500443qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014142PMC
May 2014

Actin controls the vesicular fraction of dopamine released during extended kiss and run exocytosis.

ACS Chem Biol 2014 Mar 21;9(3):812-20. Epub 2014 Jan 21.

Department of Chemistry and Molecular Biology, University of Gothenburg , S-41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/cb400665fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985473PMC
March 2014

Two modes of exocytosis in an artificial cell.

Sci Rep 2014 Jan 24;4:3847. Epub 2014 Jan 24.

Chalmers University of Technology, Department of Chemical and Biological Engineering, 412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1038/srep03847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900996PMC
January 2014

Single-cell imaging mass spectrometry.

Curr Opin Chem Biol 2013 Oct 12;17(5):854-9. Epub 2013 Aug 12.

Kemivagen 10, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2013.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823831PMC
October 2013

Capillary electrophoresis-mass spectrometry-based detection of drugs and neurotransmitters in Drosophila brain.

Anal Chem 2013 Sep 19;85(17):8448-54. Epub 2013 Aug 19.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac401920vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794364PMC
September 2013

Time-of-flight secondary ion mass spectrometry based molecular histology of human spinal cord tissue and motor neurons.

Anal Chem 2013 Sep 27;85(18):8741-8. Epub 2013 Aug 27.

National Center for Imaging Mass Spectrometry, Gothenburg University and Chalmers University of Technology , Sweden.

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http://dx.doi.org/10.1021/ac401830mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871880PMC
September 2013

Carbon nanotube fiber microelectrodes show a higher resistance to dopamine fouling.

Anal Chem 2013 Aug 8;85(15):7447-53. Epub 2013 Jul 8.

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg 41296, Sweden.

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http://dx.doi.org/10.1021/ac401399sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276597PMC
August 2013

Evaluating the diffusion coefficient of dopamine at the cell surface during amperometric detection: disk vs ring microelectrodes.

Anal Chem 2013 Jul 12;85(13):6421-8. Epub 2013 Jun 12.

Department of Chemistry and Molecular Biology, University of Gothenburg, S-41296, Gothenburg, Sweden.

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http://pubs.acs.org/doi/10.1021/ac400965d
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http://dx.doi.org/10.1021/ac400965dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737586PMC
July 2013

Amperometric measurements at cells support a role for dynamin in the dilation of the fusion pore during exocytosis.

Chemphyschem 2013 Jul 3;14(10):2295-301. Epub 2013 Jul 3.

Department of Chemistry and Molecular Biology, University of Gothenburg, S-41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1002/cphc.201300319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794367PMC
July 2013

Individually addressable thin-film ultramicroelectrode array for spatial measurements of single vesicle release.

Anal Chem 2013 Jun 16;85(11):5600-8. Epub 2013 May 16.

Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden.

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http://dx.doi.org/10.1021/ac4009385DOI Listing
June 2013

Amperometric post spike feet reveal most exocytosis is via extended kiss-and-run fusion.

Sci Rep 2012 30;2:907. Epub 2012 Nov 30.

University of Gothenburg, Department of Chemistry and Molecular Biology, 41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1038/srep00907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510463PMC
May 2013

Imaging mass spectrometry in neuroscience.

ACS Chem Neurosci 2013 May 30;4(5):666-79. Epub 2013 Apr 30.

National Center for Imaging Mass Spectrometry, Gothenburg University and Chalmers University of Technology , Gothenburg, Sweden.

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http://dx.doi.org/10.1021/cn400053cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656743PMC
May 2013

Single cell amperometry reveals glycocalyx hinders the release of neurotransmitters during exocytosis.

Anal Chem 2013 May 11;85(9):4822-8. Epub 2013 Apr 11.

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac4008682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696406PMC
May 2013

Oral administration of methylphenidate blocks the effect of cocaine on uptake at the Drosophila dopamine transporter.

ACS Chem Neurosci 2013 Apr 25;4(4):566-74. Epub 2013 Feb 25.

Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, SE-412 96, Göteborg, Sweden.

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http://dx.doi.org/10.1021/cn3002009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629741PMC
April 2013

Freeze-drying as sample preparation for micellar electrokinetic capillary chromatography-electrochemical separations of neurochemicals in Drosophila brains.

Anal Chem 2013 Mar 22;85(5):2841-6. Epub 2013 Feb 22.

Department of Molecular Biology and Chemistry, Analytical Chemistry, University of Gothenburg, Kemivägen 10, SE-412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac303377xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624619PMC
March 2013

Single-cell lipidomics: characterizing and imaging lipids on the surface of individual Aplysia californica neurons with cluster secondary ion mass spectrometry.

Anal Chem 2013 Feb 4;85(4):2231-8. Epub 2013 Feb 4.

Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.

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http://dx.doi.org/10.1021/ac303038jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867296PMC
February 2013

Chemical analysis of single cells.

Anal Chem 2013 Jan 30;85(2):522-42. Epub 2012 Nov 30.

University of Gothenburg, Department of Chemistry and Molecular Biology, 41296 Gothenburg, Sweden.

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http://pubs.acs.org/doi/10.1021/ac303290s
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January 2013

Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena pyriformis.

Surf Interface Anal 2013 Jan 14;45(1):211-214. Epub 2012 Jun 14.

Department of Chemistry, University of Gothenburg, SE-41296, Göteborg, Sweden.

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http://dx.doi.org/10.1002/sia.5017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525492PMC
January 2013

C(60)-SIMS Studies of Glycerophospholipid in a LIPID MAPS Model System: KDO(2)-Lipid A Stimulated RAW 264.7 Cells.

Surf Interface Anal 2013 Jan 3;45(1):298-301. Epub 2012 May 3.

The Pennsylvania State University, Chemistry Building, University Park, PA 16802 ; The University of Gothenburg, Department of Chemistry, S-41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/sia.5036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524986PMC
January 2013

C60-ToF SIMS imaging of frozen hydrated HeLa cells.

Surf Interface Anal 2013 Jan;45(1):302-304

The Dow Chemical Company, 727 Norristown Road, Spring House, Pennsylvania 19002, United States.

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http://dx.doi.org/10.1002/sia.4882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620711PMC
January 2013

Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods.

Analyst 2012 Apr 16;137(8):1755-63. Epub 2012 Feb 16.

Department of Chemical and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden.

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April 2012

Carbon-ring microelectrode arrays for electrochemical imaging of single cell exocytosis: fabrication and characterization.

Anal Chem 2012 Mar 6;84(6):2949-54. Epub 2012 Mar 6.

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac3000368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311994PMC
March 2012

Relative quantification of phospholipid accumulation in the PC12 cell plasma membrane following phospholipid incubation using TOF-SIMS imaging.

Anal Chem 2011 Jul 1;83(13):5337-43. Epub 2011 Jun 1.

Department of Chemistry, University of Gothenburg, SE-41296 Göteborg, Sweden.

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http://dx.doi.org/10.1021/ac200771gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129869PMC
July 2011

Chemical analysis of single cells.

Anal Chem 2011 Jun 28;83(12):4369-92. Epub 2011 Apr 28.

Department of Chemistry, University of Gothenburg, S-41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1021/ac2009838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115477PMC
June 2011

Mechanics of lipid bilayer junctions affecting the size of a connecting lipid nanotube.

Nanoscale Res Lett 2011 Jun 14;6(1):421. Epub 2011 Jun 14.

BioNano Systems Laboratory, Institute for Microtechnology and Nanoscience, Chalmers University of Technology, 41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1186/1556-276X-6-421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211838PMC
June 2011

Ruthenium(II) Complex Enantiomers as Cellular Probes for Diastereomeric Interactions in Confocal and Fluorescence Lifetime Imaging Microscopy.

J Phys Chem Lett 2011 Feb;2(5):397-401

Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-41296 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/jz101580eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065721PMC
February 2011

Trends in computational simulations of electrochemical processes under hydrodynamic flow in microchannels.

Anal Bioanal Chem 2011 Jan 24;399(1):183-90. Epub 2010 Aug 24.

Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.

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January 2011

Lipid detection, identification, and imaging single cells with SIMS.

Methods Mol Biol 2010 ;656:85-97

Department of Chemistry, The University of Arizona, Tucson, AZ, USA.

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December 2010

Estradiol inhibits depolarization-evoked exocytosis in PC12 cells via N-type voltage-gated calcium channels.

Cell Mol Neurobiol 2010 Nov 19;30(8):1235-42. Epub 2010 Nov 19.

Department of Chemistry, The Pennsylvania State University, 104 Chemistry Research Building, University Park, PA 16802, USA.

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November 2010

Electrochemical probes for detection and analysis of exocytosis and vesicles.

Chemphyschem 2010 Sep;11(13):2756-63

Department of Chemistry, University of Gothenburg, 41296 Göteborg, Sweden.

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http://dx.doi.org/10.1002/cphc.201000258DOI Listing
September 2010

Biogenic amines in microdissected brain regions of Drosophila melanogaster measured with micellar electrokinetic capillary chromatography-electrochemical detection.

Anal Chem 2010 Sep;82(18):7729-35

Department of Chemistry, The Pennsylvania State University, 125 Chemistry Building, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1021/ac101603dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939159PMC
September 2010

Analytical approaches to investigate transmitter content and release from single secretory vesicles.

Anal Bioanal Chem 2010 Aug 18;397(8):3269-79. Epub 2010 May 18.

Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.

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August 2010

Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor.

Langmuir 2010 Jun;26(12):10386-91

Department of Chemistry, The Pennsylvania State University, 125 Chemistry Building, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1021/la100134rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774550PMC
June 2010

Only a Fraction of Quantal Content is Released During Exocytosis as Revealed by Electrochemical Cytometry of Secretory Vesicles.

ACS Chem Neurosci 2010 Mar;1(3):234-245

Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802.

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http://pubs.acs.org/doi/10.1021/cn900040e
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847285PMC
March 2010

Steady-state electrochemical determination of lipidic nanotube diameter utilizing an artificial cell model.

Anal Chem 2010 Feb;82(3):1020-6

Department of Chemistry, 104 Chemistry Research Building, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://pubs.acs.org/doi/abs/10.1021/ac902282d
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814003PMC
February 2010

Micellar capillary electrophoresis--electrochemical detection of neurochemicals from Drosophila.

J Sep Sci 2010 Feb;33(3):388-93

Department of Chemistry, The Pennsylvania State University, University Park, USA.

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http://doi.wiley.com/10.1002/jssc.200900634
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February 2010

Mass spectrometry imaging of mating Tetrahymena show that changes in cell morphology regulate lipid domain formation.

Proc Natl Acad Sci U S A 2010 Feb 1;107(7):2751-6. Epub 2010 Feb 1.

Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1073/pnas.0908101107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840282PMC
February 2010

Chemical measurements in Drosophila.

Trends Analyt Chem 2009 Dec;28(11):1223-1234

Department of Chemistry, The Pennsylvania State University, 125 Chemistry Building, University Park, PA 16802, USA.

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http://dx.doi.org/10.1016/j.trac.2009.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786087PMC
December 2009

Quantitative chemical analysis of single cells.

Methods Mol Biol 2009 ;544:153-62

Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1007/978-1-59745-483-4_11DOI Listing
November 2009

Temporal analysis of protozoan lysis in a microfluidic device.

Lab Chip 2009 Oct 3;9(19):2796-802. Epub 2009 Jul 3.

Department of Chemistry, The Pennsylvania State University, University Park, PA, USA.

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http://dx.doi.org/10.1039/b907942dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801346PMC
October 2009

Hybrid capillary-microfluidic device for the separation, lysis, and electrochemical detection of vesicles.

Anal Chem 2009 Mar;81(6):2294-302

Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://pubs.acs.org/doi/abs/10.1021/ac802466g
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656409PMC
March 2009