Andrew F Wilks

Andrew F Wilks

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Andrew F Wilks

Andrew F Wilks

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

The Use of JAK-specific inhibitors as chemical biology tools.

Methods Mol Biol 2013 ;967:99-113

Chemical Biology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-242-1_7DOI Listing
June 2013

Plasmodium kinases as targets for new-generation antimalarials.

Future Med Chem 2012 Dec;4(18):2295-310

Department of Biochemistry & Molecular Biology, School of Biomedical Sciences, Monash University, Wellington Road, Clayton VIC, 3800, Australia.

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http://dx.doi.org/10.4155/fmc.12.183DOI Listing
December 2012

c-FMS inhibitors: a patent review.

Expert Opin Ther Pat 2011 Feb 5;21(2):147-65. Epub 2011 Jan 5.

The Walter and Eliza Hall Institute of Medical Research, 4 Research Avenue, La Trobe R & D Park, Bundoora, VIC 3086, Australia.

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http://dx.doi.org/10.1517/13543776.2011.545348DOI Listing
February 2011

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

J Mol Biol 2009 Mar 29;387(1):219-32. Epub 2009 Jan 29.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00222836090009
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http://dx.doi.org/10.1016/j.jmb.2009.01.041DOI Listing
March 2009

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages.

J Leukoc Biol 2009 Feb 12;85(2):278-88. Epub 2008 Nov 12.

The University of Queensland, Institute for Molecular Bioscience, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1189/jlb.0808497DOI Listing
February 2009

The JAK kinases: not just another kinase drug discovery target.

Authors:
Andrew F Wilks

Semin Cell Dev Biol 2008 Aug 5;19(4):319-28. Epub 2008 Aug 5.

SYN|thesis med chem, PO Box 450, South Yarra, Victoria 3141, Australia.

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http://dx.doi.org/10.1016/j.semcdb.2008.07.020DOI Listing
August 2008

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

J Mol Biol 2007 Mar 20;367(3):839-47. Epub 2007 Jan 20.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360700076
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http://dx.doi.org/10.1016/j.jmb.2007.01.036DOI Listing
March 2007

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations.

FASEB J 2006 Sep 28;20(11):1921-3. Epub 2006 Jul 28.

Cooperative Research Centre for Chronic Inflammatory Diseases and Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1096/fj.06-5848fjeDOI Listing
September 2006

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

Blood 2006 Jan 20;107(1):176-83. Epub 2005 Sep 20.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1182/blood-2005-06-2413DOI Listing
January 2006