Andrew Ellington

Andrew Ellington

UNVERIFIED PROFILE

Are you Andrew Ellington?   Register this Author

Register author
Andrew Ellington

Andrew Ellington

Publications by authors named "Andrew Ellington"

Are you Andrew Ellington?   Register this Author

100Publications

1388Reads

26Profile Views

Bringing Microscopy-By-Sequencing into View.

Trends Biotechnol 2020 Feb 12;38(2):154-162. Epub 2019 Aug 12.

Center for Systems and Synthetic Biology, Institute of Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tibtech.2019.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943198PMC
February 2020

Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics.

Acta Biomater 2020 Jan 21;102:315-325. Epub 2019 Nov 21.

J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, 1275 Center Dr, Gainesville, FL 32615, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actbio.2019.11.037DOI Listing
January 2020

Engineered symbionts activate honey bee immunity and limit pathogens.

Science 2020 01 30;367(6477):573-576. Epub 2020 Jan 30.

Department of Integrative Biology, The University of Texas at Austin, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aax9039DOI Listing
January 2020

Does Biotechnology Pose New Catastrophic Risks?

Curr Top Microbiol Immunol 2019 ;424:107-119

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/82_2019_177DOI Listing
December 2019

Retrons and their applications in genome engineering.

Nucleic Acids Res 2019 Dec;47(21):11007-11019

Center for Systems and Synthetic Biology and Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkz865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868368PMC
December 2019

Expanding the limits of the second genetic code with ribozymes.

Nat Commun 2019 11 8;10(1):5097. Epub 2019 Nov 8.

Department of Chemical and Biological Engineering, Northwestern University, Evanston, 60208, IL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-12916-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841967PMC
November 2019

Single-Molecule Mechanistic Study of Enzyme Hysteresis.

ACS Cent Sci 2019 Oct 24;5(10):1691-1698. Epub 2019 Sep 24.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acscentsci.9b00718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813718PMC
October 2019

Reprogramming the brain with synthetic neurobiology.

Curr Opin Biotechnol 2019 08 17;58:37-44. Epub 2018 Nov 17.

Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, 2500 Speedway, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09581669183015
Publisher Site
http://dx.doi.org/10.1016/j.copbio.2018.10.013DOI Listing
August 2019

Synthetic evolution.

Nat Biotechnol 2019 07 17;37(7):730-743. Epub 2019 Jun 17.

Center for Systems and Synthetic Biology and Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41587-019-0157-4DOI Listing
July 2019

Aptamers in Education: Undergraduates Make Aptamers and Acquire 21st Century Skills Along the Way.

Sensors (Basel) 2019 Jul 25;19(15). Epub 2019 Jul 25.

Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s19153270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696043PMC
July 2019

Pattern Generation with Nucleic Acid Chemical Reaction Networks.

Chem Rev 2019 May 13;119(10):6370-6383. Epub 2019 Mar 13.

Institute for Cellular and Molecular Biology , University of Texas at Austin , Austin , Texas 78712 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.chemrev.8b00625DOI Listing
May 2019

The Role of tRNA in Establishing New Genetic Codes.

Biochemistry 2019 03 14;58(11):1460-1463. Epub 2018 Nov 14.

Department of Molecular Biosciences , The University of Texas at Austin , Austin , Texas 78712 , United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.biochem.8b00834
Publisher Site
http://dx.doi.org/10.1021/acs.biochem.8b00834DOI Listing
March 2019

Supercharging enables organized assembly of synthetic biomolecules.

Nat Chem 2019 03 14;11(3):204-212. Epub 2019 Jan 14.

Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41557-018-0196-3DOI Listing
March 2019

Selection of self-priming molecular replicators.

Nucleic Acids Res 2019 03;47(5):2169-2176

Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkz044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412129PMC
March 2019

Cellular reagents for diagnostics and synthetic biology.

PLoS One 2018 15;13(8):e0201681. Epub 2018 Aug 15.

Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201681PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093680PMC
February 2019

Effective design principles for leakless strand displacement systems.

Proc Natl Acad Sci U S A 2018 12 13;115(52):E12182-E12191. Epub 2018 Dec 13.

Electrical and Computer Engineering, University of Texas at Austin, Austin, TX 78712;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1806859115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310779PMC
December 2018

Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay.

Viruses 2018 12 14;10(12). Epub 2018 Dec 14.

Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1999-4915/10/12/714
Publisher Site
http://dx.doi.org/10.3390/v10120714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316447PMC
December 2018

Retroelement-Based Genome Editing and Evolution.

ACS Synth Biol 2018 11 26;7(11):2600-2611. Epub 2018 Oct 26.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssynbio.8b00273DOI Listing
November 2018

Continuous directed evolution for strain and protein engineering.

Curr Opin Biotechnol 2018 10 13;53:158-163. Epub 2018 Feb 13.

Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, 2500 Speedway, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.copbio.2017.12.020DOI Listing
October 2018

Predicting Evolution of the Transcription Regulatory Network in a Bacteriophage.

Genome Biol Evol 2018 10 1;10(10):2614-2628. Epub 2018 Oct 1.

Center for Systems and Synthetic Biology, Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas, Austin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gbe/evy191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171733PMC
October 2018

A highly parallel strategy for storage of digital information in living cells.

BMC Biotechnol 2018 10 17;18(1):64. Epub 2018 Oct 17.

Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, USA.

View Article

Download full-text PDF

Source
https://bmcbiotechnol.biomedcentral.com/articles/10.1186/s12
Publisher Site
http://dx.doi.org/10.1186/s12896-018-0476-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191901PMC
October 2018

Evolution of a Thermophilic Strand-Displacing Polymerase Using High-Temperature Isothermal Compartmentalized Self-Replication.

Biochemistry 2018 08 18;57(31):4607-4619. Epub 2018 Apr 18.

Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences , University of Texas , 2500 Speedway , Austin , Texas 78712 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.biochem.8b00200DOI Listing
August 2018

Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains.

Nat Biotechnol 2018 08 4;36(7):624-631. Epub 2018 Jun 4.

Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.4154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035053PMC
August 2018

In Vitro Transcription Networks Based on Hairpin Promoter Switches.

ACS Synth Biol 2018 08 1;7(8):1937-1945. Epub 2018 Aug 1.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acssynbio.8b00172
Publisher Site
http://dx.doi.org/10.1021/acssynbio.8b00172DOI Listing
August 2018

Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone.

PLoS Negl Trop Dis 2018 08 30;12(8):e0006671. Epub 2018 Aug 30.

Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, United States of America.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pntd.0006671
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0006671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116922PMC
August 2018

Construction of synthetic T7 RNA polymerase expression systems.

Methods 2018 07 5;143:110-120. Epub 2018 Mar 5.

Department of Molecular Biosciences, University of Texas at Austin, TX, United States; Centre of System and Synthetic Biology, University of Texas at Austin, TX, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymeth.2018.02.022DOI Listing
July 2018

Fingerprinting Non-Terran Biosignatures.

Astrobiology 2018 07 8;18(7):915-922. Epub 2018 Mar 8.

5 Institute for Cell and Molecular Biology, The University of Texas at Austin , Austin, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ast.2017.1712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067094PMC
July 2018

Phosphorothioated Primers Lead to Loop-Mediated Isothermal Amplification at Low Temperatures.

Anal Chem 2018 07 5;90(14):8290-8294. Epub 2018 Jul 5.

Institute for Cellular and Molecular Biology, Department of Molecular Biosciences , University of Texas at Austin , Austin , Texas 78712 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.8b02062DOI Listing
July 2018

Strand Displacement Probes Combined with Isothermal Nucleic Acid Amplification for Instrument-Free Detection from Complex Samples.

Anal Chem 2018 06 8;90(11):6580-6586. Epub 2018 May 8.

Weldon School of Biomedical Engineering , Purdue University , West Lafayette , Indiana 47907 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.8b00269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990927PMC
June 2018

Directed Evolution of Heterologous tRNAs Leads to Reduced Dependence on Post-transcriptional Modifications.

ACS Synth Biol 2018 05 25;7(5):1315-1327. Epub 2018 Apr 25.

McKetta Department of Chemical Engineering , The University of Texas at Austin , Austin , Texas 78712 , United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acssynbio.7b00421
Publisher Site
http://dx.doi.org/10.1021/acssynbio.7b00421DOI Listing
May 2018

Directed evolution of a synthetic phylogeny of programmable Trp repressors.

Nat Chem Biol 2018 04 26;14(4):361-367. Epub 2018 Feb 26.

Department of Molecular Biosciences, Center for Systems and Synthetic Biology, Austin, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41589-018-0006-7DOI Listing
April 2018

Portable platform for rapid in-field identification of human fecal pollution in water.

Water Res 2018 03 13;131:186-195. Epub 2017 Dec 13.

Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.watres.2017.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999531PMC
March 2018

Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9.

Bio Protoc 2018 Mar;8(6)

Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21769/BioProtoc.2765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951413PMC
March 2018

Compartmentalized Self-Replication for Evolution of a DNA Polymerase.

Curr Protoc Chem Biol 2018 03;10(1):1-17

Center for Systems and Synthetic Biology University of Texas at Austin, Austin, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpch.34DOI Listing
March 2018

Evolving Bacterial Fitness with an Expanded Genetic Code.

Sci Rep 2018 02 19;8(1):3288. Epub 2018 Feb 19.

Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-21549-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818497PMC
February 2018

Viral attenuation by engineered protein fragmentation.

Virus Evol 2018 Jan 19;4(1):vey017. Epub 2018 Jun 19.

Department of Integrative Biology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ve/vey017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009699PMC
January 2018

Compartmentalized partnered replication for the directed evolution of genetic parts and circuits.

Nat Protoc 2017 Dec 9;12(12):2493-2512. Epub 2017 Nov 9.

Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2017.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053311PMC
December 2017

Genetic alphabet expansion transcription generating functional RNA molecules containing a five-letter alphabet including modified unnatural and natural base nucleotides by thermostable T7 RNA polymerase variants.

Chem Commun (Camb) 2017 Nov;53(91):12309-12312

Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #09-01, Singapore 138669, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7cc06661aDOI Listing
November 2017

Differential array sensing for cancer cell classification and novelty detection.

Org Biomol Chem 2017 Nov;15(46):9866-9874

Department of Chemistry, The University of Texas at Austin, 100 E. 24th Street, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7ob02174gDOI Listing
November 2017

Charge Shielding Prevents Aggregation of Supercharged GFP Variants at High Protein Concentration.

Mol Pharm 2017 10 18;14(10):3269-3280. Epub 2017 Sep 18.

Departments of †Chemical Engineering and ‡Molecular Biosciences, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.molpharmaceut.7b00322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624851PMC
October 2017

Amplicon Competition Enables End-Point Quantitation of Nucleic Acids Following Isothermal Amplification.

Chembiochem 2017 09 17;18(17):1692-1695. Epub 2017 Jul 17.

Department of Molecular Biosciences, College of Natural Sciences, The University of Texas, Austin, TX, 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbic.201700317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890436PMC
September 2017

A Simple, Cleated DNA Walker That Hangs on to Surfaces.

ACS Nano 2017 08 18;11(8):8047-8054. Epub 2017 Jul 18.

Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsnano.7b02693DOI Listing
August 2017

Purification of single-stranded DNA by co-polymerization with acrylamide and electrophoresis.

Biotechniques 2017 06 1;62(6):275-282. Epub 2017 Jun 1.

University of Idaho, Department of Chemistry, Moscow, ID.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2144/000114557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800053PMC
June 2017

Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips.

Cell 2017 Jun;170(1):35-47.e13

Department of Molecular Biosciences and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA; Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.05.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552236PMC
June 2017

Evolving Orthogonal Suppressor tRNAs To Incorporate Modified Amino Acids.

ACS Synth Biol 2017 01 21;6(1):108-119. Epub 2016 Sep 21.

Center for Systems and Synthetic Biology, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssynbio.6b00145DOI Listing
January 2017

Coupling Sensitive Nucleic Acid Amplification with Commercial Pregnancy Test Strips.

Angew Chem Int Ed Engl 2017 01 19;56(4):992-996. Epub 2016 Dec 19.

Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, Department of Chemistry, The University of Texas at Austin, Austin, TX, 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201609108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240841PMC
January 2017

Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology.

Cold Spring Harb Perspect Biol 2017 Jan 3;9(1). Epub 2017 Jan 3.

Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a023812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204324PMC
January 2017

A primerless molecular diagnostic: phosphorothioated-terminal hairpin formation and self-priming extension (PS-THSP).

Anal Bioanal Chem 2016 Dec 31;408(30):8583-8591. Epub 2016 Mar 31.

Institute for Cellular and Molecular Biology, Department of Chemistry and Biochemistry, University of Texas at Austin, 2500 Speedway MBB 3.424, Austin, TX, 78712, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045755PMC
http://dx.doi.org/10.1007/s00216-016-9479-yDOI Listing
December 2016

Strand-Exchange Nucleic Acid Circuitry with Enhanced Thermo-and Structure- Buffering Abilities Turns Gene Diagnostics Ultra-Reliable and Environmental Compatible.

Sci Rep 2016 11 4;6:36605. Epub 2016 Nov 4.

State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun, Jilin, 130022, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep36605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095676PMC
November 2016

Design and engineering of a transmissible antiviral defense.

J Biol Eng 2016 12;10:12. Epub 2016 Oct 12.

Department of Integrative Biology, University of Texas at Austin, Austin, 78712 TX USA ; Institute of Cellular and Molecular Biology, University of Texas at Austin, Austin, 78712 TX USA ; Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, 78712 TX USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13036-016-0033-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062863PMC
October 2016

Synthesis of alanyl nucleobase amino acids and their incorporation into proteins.

Bioorg Med Chem 2016 09 6;24(18):4177-4187. Epub 2016 Jul 6.

Biodesign Center for BioEnergetics and School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2016.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992614PMC
September 2016

Recent advances in synthetic biosafety.

F1000Res 2016 31;5. Epub 2016 Aug 31.

Department of Chemistry & Biochemistry, University of Texas at Austin, Austin, TX, 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/f1000research.8365.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007755PMC
September 2016

An in vitro selection for small molecule induced switching RNA molecules.

Methods 2016 08 17;106:51-7. Epub 2016 Feb 17.

CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymeth.2016.02.010DOI Listing
August 2016

Expanded Genetic Codes Create New Mutational Routes to Rifampicin Resistance in Escherichia coli.

Mol Biol Evol 2016 08 9;33(8):2054-63. Epub 2016 May 9.

Center for Systems and Synthetic Biology, Center for Computational Biology and Bioinformatics, Institute for Cellular and Molecular Biology, Department of Molecular BioSciences, The University of Texas at Austin

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msw094DOI Listing
August 2016

Virus wars: using one virus to block the spread of another.

PeerJ 2016 29;4:e2166. Epub 2016 Jun 29.

Department of Integrative Biology, University of Texas, Austin, TX, United States; The Institute for Cellular and Molecular Biology, University of Texas, Austin, TX, United States; Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7717/peerj.2166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933091PMC
July 2016

Synthesis and structural analyses of phenylethynyl-substituted tris(2-pyridylmethyl)amines and their copper(ii) complexes.

Dalton Trans 2016 Jun;45(26):10585-98

Department of Chemistry, The University of Texas at Austin, Austin, Texas 78752, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6dt00473cDOI Listing
June 2016

Synthetic evolutionary origin of a proofreading reverse transcriptase.

Science 2016 Jun;352(6293):1590-3

Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, 2500 Speedway, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.aaf5409
Publisher Site
http://dx.doi.org/10.1126/science.aaf5409DOI Listing
June 2016

Paper diagnostic device for quantitative electrochemical detection of ricin at picomolar levels.

Lab Chip 2015 ;15(18):3707-15

Department of Chemistry, The University of Texas at Austin, 105 E. 24th St., Stop A5300, Austin, TX, 78712 USA.

View Article

Download full-text PDF

Source
http://rcrooks.cm.utexas.edu/research/resources/Publications
Web Search
http://xlink.rsc.org/?DOI=C5LC00731C
Publisher Site
http://dx.doi.org/10.1039/c5lc00731cDOI Listing
May 2016

Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires.

Proc Natl Acad Sci U S A 2016 May 25;113(19):E2636-45. Epub 2016 Apr 25.

Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712; Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, TX 78712; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712

View Article

Download full-text PDF

Source
http://www.pnas.org/content/113/19/E2636.full.pdf
Web Search
http://www.pnas.org/content/suppl/2016/04/24/1525510113.DCSu
Web Search
http://www.pnas.org/lookup/doi/10.1073/pnas.1525510113
Publisher Site
http://dx.doi.org/10.1073/pnas.1525510113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868480PMC
May 2016

Addicting diverse bacteria to a noncanonical amino acid.

Nat Chem Biol 2016 Mar 18;12(3):138-40. Epub 2016 Jan 18.

Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nchembio.2002DOI Listing
March 2016

Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes.

Nat Protoc 2016 Mar 4;11(3):429-42. Epub 2016 Feb 4.

Department of Chemical Engineering, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2016.024DOI Listing
March 2016

Engineering Signaling Aptamers That Rely on Kinetic Rather Than Equilibrium Competition.

Anal Chem 2016 Feb 25;88(4):2250-7. Epub 2016 Jan 25.

Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, and Department of Chemistry, The University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.5b03930DOI Listing
February 2016

Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV).

PLoS One 2015 9;10(4):e0123126. Epub 2015 Apr 9.

Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123126PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391951PMC
December 2015

Landscape-Based Biology.

J Mol Evol 2015 Dec 19;81(5-6):144-5. Epub 2015 Oct 19.

Center for Systems and Synthetic Biology, University of Texas at Austin, University Station A4800, Austin, TX, 78712-0165, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00239-015-9706-8DOI Listing
December 2015

One-step tumor detection from dynamic morphology tracking on aptamer-grafted surfaces.

Technology (Singap World Sci) 2015 Dec 16;3(4):194-200. Epub 2015 Nov 16.

Nano-Bio Lab, University of Texas at Arlington, TX 76019, USA; Department of Electrical Engineering, University of Texas at Arlington, TX 76010, USA; Nanotechnology Research Center, University of Texas at Arlington, TX 76019, USA; Department of Biology, University of Texas at Arlington, TX 76019, USA; Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1142/S2339547815500089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703374PMC
December 2015

Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses.

J Virol 2015 Nov 9;89(22):11643-53. Epub 2015 Sep 9.

Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA Department of Molecular, Cellular, and Developmental Biology and the BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, USA

View Article

Download full-text PDF

Source
http://jvi.asm.org/lookup/doi/10.1128/JVI.01408-15
Publisher Site
http://dx.doi.org/10.1128/JVI.01408-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645654PMC
November 2015

Directed Evolution of a Panel of Orthogonal T7 RNA Polymerase Variants for in Vivo or in Vitro Synthetic Circuitry.

ACS Synth Biol 2015 Oct 7;4(10):1070-6. Epub 2014 Oct 7.

Institute for Cellular and Molecular Biology, ‡Department of Chemistry and Biochemistry, and §Center for Systems & Synthetic Biology, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/sb500299c
Publisher Site
http://dx.doi.org/10.1021/sb500299cDOI Listing
October 2015

Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.

ACS Chem Biol 2015 Oct 15;10(10):2405-14. Epub 2015 Sep 15.

Department of Molecular Biosciences and Institute for Cellular and Molecular Biology, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschembio.5b00296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788383PMC
October 2015

Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment.

Elife 2015 Oct 14;4. Epub 2015 Oct 14.

Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.09696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718724PMC
October 2015

Industrialization of Biology.

ACS Synth Biol 2015 Oct;4(10):1053-5

Center for Systems and Synthetic Biology, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssynbio.5b00190DOI Listing
October 2015

Design, synthesis, and application of Spinach molecular beacons triggered by strand displacement.

Methods Enzymol 2015 5;550:215-49. Epub 2015 Jan 5.

Department of Chemistry and Biochemistry, Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.mie.2014.10.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429879PMC
September 2015

Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants.

Nucleic Acids Res 2015 Sep 24;43(15):7480-8. Epub 2015 Jul 24.

Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX 78712, USA Center for Systems & Synthetic Biology, University of Texas at Austin, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkv734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551944PMC
September 2015

Synthetic biology: Six pack and stack.

Nat Chem 2015 Aug;7(8):617-9

Institute for Cellular and Molecular Biology, University of Texas at Austin, University Station A4800, Austin, Texas 78712-0165, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nchem.2313DOI Listing
August 2015

Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry.

J Am Chem Soc 2015 Jul 9;137(28):9128-35. Epub 2015 Jul 9.

†Department of Chemistry and ‡Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b04628DOI Listing
July 2015

A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers.

Sci Rep 2015 Jun 8;5:11039. Epub 2015 Jun 8.

Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep11039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458886PMC
June 2015

Next-generation sequencing as input for chemometrics in differential sensing routines.

Angew Chem Int Ed Engl 2015 May 31;54(21):6339-42. Epub 2015 Mar 31.

Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78712 (USA).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201501822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426058PMC
May 2015

RNA as a conception.

RNA 2015 Apr;21(4):608

Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1261/rna.050443.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371301PMC
April 2015

Controlled assembly of artificial protein-protein complexes via DNA duplex formation.

Bioconjug Chem 2015 Mar 17;26(3):427-34. Epub 2015 Feb 17.

†School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bc500473sDOI Listing
March 2015

Robust strand exchange reactions for the sequence-specific, real-time detection of nucleic acid amplicons.

Anal Chem 2015 Mar 2;87(6):3314-20. Epub 2015 Mar 2.

†Center for Systems and Synthetic Biology, ‡Department of Chemistry, §Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ac504387cDOI Listing
March 2015

High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication.

Mol Ther Nucleic Acids 2015 Feb 17;4:e228. Epub 2015 Feb 17.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mtna.2015.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345311PMC
February 2015

A microbial model of economic trading and comparative advantage.

J Theor Biol 2015 Jan 28;364:326-43. Epub 2014 Sep 28.

Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA; Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX 78712, USA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtbi.2014.09.030DOI Listing
January 2015

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire.

Nat Med 2015 Jan 15;21(1):86-91. Epub 2014 Dec 15.

1] Department of Chemical Engineering, University of Texas at Austin, Austin, Texas, USA. [2] Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas, USA. [3] Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, USA. [4] Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas, USA.

View Article

Download full-text PDF

Source
http://sites.utexas.edu/texas-bmes/files/2015/07/2015-In-dep
Web Search
http://dx.doi.org/10.1038/nm.3743DOI Listing
January 2015

Evolving tRNA(Sec) for efficient canonical incorporation of selenocysteine.

J Am Chem Soc 2015 Jan 23;137(1):46-9. Epub 2014 Dec 23.

Institute for Cellular and Molecular Biology, University of Texas at Austin , Austin, Texas 78712, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja510695gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432777PMC
January 2015

3D Printing with Nucleic Acid Adhesives.

ACS Biomater Sci Eng 2015 Jan 17;1(1):19-26. Epub 2014 Dec 17.

Departmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ab500026fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426351PMC
January 2015

Differential sensing of MAP kinases using SOX-peptides.

Angew Chem Int Ed Engl 2014 Dec 15;53(51):14064-8. Epub 2014 Oct 15.

Department of Chemistry and Biochemistry, The University of Texas at Austin, 1 University Station A1590, Austin, Texas 78712 (USA).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201408256DOI Listing
December 2014

In vitro selection using modified or unnatural nucleotides.

Curr Protoc Nucleic Acid Chem 2014 Mar 26;56:9.6.1-33. Epub 2014 Mar 26.

The University of Texas at Austin, Austin, Texas; Altermune Technologies LLC, Austin, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142700.nc0906s56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068349PMC
March 2014