Andrew Demchuk

Andrew Demchuk

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Andrew Demchuk

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Accuracy and Reliability of Multiphase CTA Perfusion for Identifying Ischemic Core.

Clin Neuroradiol 2019 09 21;29(3):543-552. Epub 2018 Aug 21.

Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, 3330 Hospital Drive NW, AB T2N 4N1, Calgary, Canada.

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http://dx.doi.org/10.1007/s00062-018-0717-xDOI Listing
September 2019

Correction to: Accuracy and Reliability of Multiphase CTA Perfusion for Identifying Ischemic Core.

Clin Neuroradiol 2019 09;29(3):553

Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, 3330 Hospital Drive NW, AB T2N 4N1, Calgary, Canada.

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http://dx.doi.org/10.1007/s00062-019-00803-2DOI Listing
September 2019

The emerging value of serum D-dimer measurement in the work-up and management of ischemic stroke.

Int J Stroke 2019 Sep 19:1747493019876538. Epub 2019 Sep 19.

Calgary Stroke Program, Hotchkiss Brain Institute, Departments of Clinical Neurosciences and Radiology, Cumming School of Medicine University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1177/1747493019876538DOI Listing
September 2019

Stroke Laterality Did Not Modify Outcomes in the HERMES Meta-Analysis of Individual Patient Data of 7 Trials.

Stroke 2019 Aug 5;50(8):2118-2124. Epub 2019 Jul 5.

Departments of Clinical Neurosciences and Radiology (M. Goyal), Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.118.023102DOI Listing
August 2019

New and expanding ventricular hemorrhage predicts poor outcome in acute intracerebral hemorrhage.

Neurology 2019 Aug 1;93(9):e879-e888. Epub 2019 Aug 1.

From the Ottawa Stroke Program (V.Y., D.D.), Department of Medicine (Neurology), Department of Radiology (C.L.), Ottawa Methods Center (T.R., D.F.), and Ottawa Hospital Research Institute (T.R., D.F., D.D.), University of Ottawa, Ontario; Calgary Stroke Program (A.M.D., M.D.H.), Department of Clinical Neurosciences, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Alberta; Division of Neuroradiology and Department of Medical Imaging (R.I.A.), Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; Department of Neurology (D.R.-L., C.A.M.), Hospital Universitari Vall d'Hebron, Barcelona; Department of Neurology (Y.S.), Dr. Josep Trueta University Hospital, Institut d'Investigació Biomèdica Girona Foundation, Spain; Department of Neurology (I.D.), Elblandklinikum Meissen Academic Teaching Hospital of Technische University, Dresden, Germany; Interventional Stroke and Cerebrovascular Treatment Center and 2nd Department of Neurology (A.K.), Institute of Psychiatry and Neurology, and Department of Experimental and Clinical Pharmacology, Warsaw, Poland; Department of Medicine (J.-M.B.), Charles LeMoyne Hospital, University of Sherbrooke, Longueuil, Quebec; Department of Neurology (G.G.), Dalhousie University, Halifax, Nova Scotia, Canada; Department of Neurology (P.S., R.B.), All India Institute of Medical Sciences, New Delhi; Apollo Gleneagles Hospitals (J.R.), Kolkata, India; Department of Neurology (C.S.K.), Boston Medical Center; and Department of Neurology (A.D.W., C.D.A., M.E.G., S.M.G., A.V., J.R.), Henry and Allison McCance Center for Brain Health (J.R.), and Department of Emergency Medicine (J.N.G.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000008007DOI Listing
August 2019

Automated brain extraction from head CT and CTA images using convex optimization with shape propagation.

Comput Methods Programs Biomed 2019 Jul 29;176:1-8. Epub 2019 Apr 29.

Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmpb.2019.04.030DOI Listing
July 2019

Ischemic Diffusion Lesion Reversal After Endovascular Treatment.

Stroke 2019 Jun 2;50(6):1504-1509. Epub 2019 May 2.

From the Department of Neurology (J.Y., J.-H.H., S.-I.S.), Keimyung University School of Medicine, Daegu, Korea.

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http://dx.doi.org/10.1161/STROKEAHA.118.024263DOI Listing
June 2019

Therapeutic hypothermia: Applications in adults with acute ischemic stroke.

Brain Circ 2019 Apr-Jun;5(2):43-54. Epub 2019 Jun 27.

Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.4103/bc.bc_5_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611191PMC
June 2019

eTICI reperfusion: defining success in endovascular stroke therapy.

J Neurointerv Surg 2019 May 7;11(5):433-438. Epub 2018 Sep 7.

Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1136/neurintsurg-2018-014127DOI Listing
May 2019

Tenacity of Collateral Perfusion in Proximal Cerebral Arterial Occlusions 6-12 h after Onset.

Cerebrovasc Dis 2018 7;45(5-6):263-269. Epub 2018 Jun 7.

Department of Neurology and Cerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

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http://dx.doi.org/10.1159/000489894DOI Listing
April 2019

Diffusion-weighted imaging lesion growth occurs despite recanalization in acute ischemic stroke: Implications for future treatment trials.

Int J Stroke 2019 04 4;14(3):257-264. Epub 2018 Sep 4.

1 Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1177/1747493018798550DOI Listing
April 2019

Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors.

N Engl J Med 2019 04 7;380(14):1326-1335. Epub 2019 Feb 7.

From the Population Health Research Institute (S.J.C., J.W.E., D.M.S., E.Z., B.M., S.A., J.N.) and the Department of Medicine (M. Crowther), McMaster University, Hamilton, ON, and the University of Calgary, Calgary, AB (A.M.D.) - all in Canada; Harvard Medical School (C.M.G.) and Brigham and Women's Hospital (D.J.P.) - both in Boston; Portola Pharmaceuticals, South San Francisco, CA (J.T.C., J.H.L., P.Y., M.D.B., G.L., P.B.C., S.G., J.L., S.S.); University of Leuven, Leuven, Belgium (P.V.); Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand (J.S.), and Grenoble-Alpes University Hospital, Grenoble (P.A.) - both in France; Academic Medical Center, Amsterdam (S.M.); Guy's and St. Thomas' Hospitals, King's College London, London (A.T.C.); University Hospital Carl Gustav Carus Dresden, Dresden, Germany (J.B.-W.); Instituto de Investigación Hospital Universitario La Paz, Madrid (J.L.-S.); Sarasota Memorial Hospital, Sarasota, FL (M. Concha); and Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.).

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http://dx.doi.org/10.1056/NEJMoa1814051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699827PMC
April 2019

Deferral of Consent in Acute Stroke Trials.

Stroke 2019 Apr;50(4):1017-1020

Department of Clinical Neurosciences and Community Health Sciences (M.D.H.), University of Calgary, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.118.024096DOI Listing
April 2019

STAIR X: Trial Design Considerations and Additional Populations to Expand Indications for Endovascular Treatment.

Stroke 2019 04 23:STROKEAHA119024337. Epub 2019 Apr 23.

Department of Neurology, Emory University School of Medicine, Atlanta, GA (R.G.N.).

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http://dx.doi.org/10.1161/STROKEAHA.119.024337DOI Listing
April 2019

Diffusion-Weighted MRI Stroke Volume Following Recanalization Treatment is Threshold-Dependent.

Clin Neuroradiol 2019 Mar 19;29(1):135-141. Epub 2017 Oct 19.

Calgary Stroke Program, Departments of Clinical Neurosciences, University of Calgary, 3330 Hospital Drive NW, T2N 4N1, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/s00062-017-0634-4DOI Listing
March 2019

Rapid Alteplase Administration Improves Functional Outcomes in Patients With Stroke due to Large Vessel Occlusions.

Stroke 2019 Mar;50(3):645-651

Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, Health Science Centre (M.D.H.), University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.118.021840DOI Listing
March 2019

Comprehensive assessment of disability post-stroke using the newly developed miFUNCTION scale.

Int J Stroke 2019 Mar 27:1747493019840933. Epub 2019 Mar 27.

7 Departments of Clinical Neurosciences, Community Health Sciences, Medicine, and Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/1747493019840933DOI Listing
March 2019

Selective brain cooling: Let us have a moment of science.

J Cereb Blood Flow Metab 2019 Jan 14;39(1):182-183. Epub 2018 Sep 14.

1 Department of Clinical Neurosciences, at Cumming school of Medicine, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0271678X18800274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311662PMC
January 2019

Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion.

JAMA Neurol 2018 Dec;75(12):1477-1486

Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1001/jamaneurol.2018.2424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583214PMC
December 2018

Effect of IV glyburide on adjudicated edema endpoints in the GAMES-RP Trial.

Neurology 2018 12 16;91(23):e2163-e2169. Epub 2018 Nov 16.

From the Department of Neurology and Center for Genomic Medicine (W.T.K.), and Department of Radiology, Division of Neuroradiology (J.M.R.), Massachusetts General Hospital, Boston; Divisions of Stroke, Cerebrovascular and Critical Care Neurology (M.B.B.), Brigham & Women's Hospital, Boston, MA; Department of Neuroradiology (R.v.K.), Universitätsklinikum Carl Gustav Carus, Dresden, Germany; Calgary Stroke Program (A.M.D.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Canada; Department of Public Health Sciences (J.J.E.), Medical University of South Carolina, Charleston; Department of Neurology (H.E.H.), Oregon Health Sciences University, Portland; Department of Neurology (B.J.M.), University of Pittsburgh, PA; Department of Neurosurgery (J.M.S.), University of Maryland School of Medicine, Baltimore; and Division of Neurocritical Care and Emergency Neurology (K.N.S.), Yale New Haven Hospital, CT.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282228PMC
December 2018

Symptomatic intracranial atherosclerotic disease: an ultrasound 2-year follow-up pilot study.

Neurol Sci 2018 Nov 9;39(11):1955-1959. Epub 2018 Jul 9.

Institute of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma - Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1007/s10072-018-3484-1DOI Listing
November 2018

Computed tomographic angiography in stroke and high-risk transient ischemic attack: Do not leave the emergency department without it!

Int J Stroke 2018 10 17;13(7):673-686. Epub 2018 Apr 17.

1 Department of Clinical Neurosciences, University of Calgary, Canada.

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http://dx.doi.org/10.1177/1747493018764172DOI Listing
October 2018

Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.

Lancet Neurol 2018 10 14;17(10):885-894. Epub 2018 Aug 14.

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183025
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http://dx.doi.org/10.1016/S1474-4422(18)30253-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143589PMC
October 2018

Intracerebral haemorrhage: current approaches to acute management.

Lancet 2018 10;392(10154):1257-1268

The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia; The George Institute China at Peking University Health Science Center, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)31878-6DOI Listing
October 2018

Prognosis of Acute Intracranial Atherosclerosis-Related Occlusion after Endovascular Treatment.

J Stroke 2018 Sep 30;20(3):394-403. Epub 2018 Sep 30.

Department of Neurology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

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http://dx.doi.org/10.5853/jos.2018.01627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186924PMC
September 2018

Primary to comprehensive stroke center transfers: Appropriateness, not futility.

Int J Stroke 2018 08 6;13(6):550-553. Epub 2018 Mar 6.

1 Department of Radiology and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1177/1747493018764072DOI Listing
August 2018

Combining Spot Sign and Intracerebral Hemorrhage Score to Estimate Functional Outcome: Analysis From the PREDICT Cohort.

Stroke 2018 06 2;49(6):1511-1514. Epub 2018 May 2.

Department of Neurology, Elblandklinikum Meissen, Academic Teaching Hospital of Dresden University of Technology, Meissen, Germany (I.D.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020679DOI Listing
June 2018

Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial.

J Neurointerv Surg 2018 May 11;10(5):429-433. Epub 2017 Oct 11.

Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1136/neurintsurg-2017-013316DOI Listing
May 2018

Defining CT Perfusion Thresholds for Infarction in the Golden Hour and With Ultra-Early Reperfusion.

Can J Neurol Sci 2018 05 19;45(3):339-342. Epub 2018 Feb 19.

1Calgary Stroke Program, Department of Clinical Neurosciences,University of Calgary,Calgary, Alberta,Canada.

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http://dx.doi.org/10.1017/cjn.2017.287DOI Listing
May 2018

Thrombolytic therapies for ischemic stroke: Triumphs and future challenges.

Neuropharmacology 2018 05 3;134(Pt B):272-279. Epub 2018 Mar 3.

Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1016/j.neuropharm.2017.11.010DOI Listing
May 2018

Clinical and Technological Approaches to the Prehospital Diagnosis of Large Vessel Occlusion.

Stroke 2018 04 14;49(4):1036-1043. Epub 2018 Mar 14.

From the Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, Canada (S.v.G.); and Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Alberta, Canada (A.D.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017947DOI Listing
April 2018

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging.

N Engl J Med 2018 02 24;378(8):708-718. Epub 2018 Jan 24.

From the Departments of Neurology and Neurological Sciences (G.W.A., S. Kemp, S.C., J.P.T., S.H., M.M., M.G.L.), Diagnostic Radiology (M.P.M., J.J.H., G.Z.), Radiology (R.B.), and Biomedical Data Science (P.W.L.), Stanford University School of Medicine, Stanford, and the Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles (M.K.-T.) - both in California; the Departments of Neurology, Anesthesia, Neurosurgery, and Radiology, University of Iowa, Ames (S.O.-G.); the Departments of Diagnostic Imaging, Neurology, and Neurosurgery, Warren Alpert School of Medicine at Brown University and Rhode Island Hospital, Providence (R.A.M.); the Departments of Neurology and Neurosurgery, Ohio State University, Columbus (M.T.T.), and the University of Cincinnati Gardner Neuroscience Institute and the Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati (J.C., J.P.B.) - both in Ohio; the Departments of Neurosurgery and Neurology, Massachusetts General Hospital, Boston (T.L.-M.); the Department of Neurology, University of Texas Health Science Center, Houston (A.S.); the Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia (S.E.K.); the Departments of Radiology, Neurology, and Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago (S.A.A.); the Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y., Y.Y.P.); the Department of Neurology, New York University School of Medicine, New York (S. Kim); and the Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary Cumming School of Medicine, Calgary, AB, Canada (A.M.D.).

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http://dx.doi.org/10.1056/NEJMoa1713973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590673PMC
February 2018

Secondary stroke prevention services in Canada: a cross-sectional survey and geospatial analysis of resources, capacity and geographic access.

CMAJ Open 2018 Feb;6(1):E95-E102

Affiliations: Department of Geography and Planning (Jewett), University of Toronto, Toronto, Ont.; Department of Neurology and Neurosurgery (Harroud, Côté, Wein) and Department of Medicine (Harroud, Cote, Wein), McGill University, Montréal, Que.; Calgary Stroke Program (Hill, Smith, Demchuk), Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alta; Queen Elizabeth II Health Sciences Centre (Gubitz), Dalhousie University, Halifax, NS; Division of Neurology (Sahlas), Department of Medicine, McMaster University, Hamilton, Ont.; Sunnybrook Health Sciences Centre (Gladstone) and Hurvitz Brain Sciences Research Program (Gladstone), Sunnybrook Research Institute, Department of Medicine, University of Toronto; Heart and Stroke Foundation of Canada (Lindsay), Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20170130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878947PMC
February 2018

Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space?

Stroke 2018 01 22;49(1):201-203. Epub 2017 Nov 22.

From the Department of Diagnostic Imaging, Neuroradiology Section, Ottawa Hospital Research Institute (C.L.) and Division of Neurology, Department of Medicine (D.D.), University of Ottawa, Canada; Ottawa Hospital Research Institute, Canada (D.D.); Vinayaka Neuro Multispecialty Centre, Warangal, India (A.D.); Division of Neuroradiology (R.I.A.) and Department of Medical Imaging (R.I.A.), Sunnybrook Health Sciences Centre, University of Toronto, Canada; Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona, Spain (D.R.-L., C.A.M.); Department of Neurology, Doctor Josep Trueta University Hospital, Institut d'Investigació Biomèdica Girona Foundation, Spain (Y.S.B.); Department of Neurology, Elblandklinikum Meissen Academic Teaching Hospital of the Technische University, Dresden, Germany (I.D.); Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland (A.K.); Department of Experimental and Clinical Pharmacology, Warsaw, Poland (A.K.); Department of Medicine, Charles LeMoyne Hospital, University of Sherbrooke, Montreal, Canada (J.-M.B.); Department of Neurology, Dalhousie University, Halifax, Canada (G.G.); Department of Neurology, All India Institute of Medical Sciences, New Delhi (V.P., R.B.); AMRI Neurosciences Centre, Mukundapur, Kolkata, India (J.R.); Department of Neurology, Boston Medical Center, MA (C.S.K.); and Department of Clinical Neurosciences, Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Canada (M.D.H., A.M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018716DOI Listing
January 2018

Visual Aids for Patient, Family, and Physician Decision Making About Endovascular Thrombectomy for Acute Ischemic Stroke.

Stroke 2018 01 8;49(1):90-97. Epub 2017 Dec 8.

From the Department of Neurology and Comprehensive Stroke Center (I.T., L.S., D.L., J.L.S.), Departments of Emergency Medicine and Neurology, and Comprehensive Stroke Center (S.S.), and Department of Radiology and Comprehensive Stroke Center (V.S., R.J.), David Geffen School of Medicine, University of California Los Angeles; Hospital General Universitario Gregorio Marañón with the collaboration of Comité ad-hoc de Neurólogos Jóvenes de la Sociedad Española de Neurología, Madrid, Spain (M.V.M.); School of Medicine at Federal University of São João del-Rei (UFSJ), Brazil (M.F.Z.A.); Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA (N.G.); Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, Foothills Hospital (A.D.) and Calgary Stroke Program, Departments of Clinical Neurosciences and Radiology, Seaman Family MR Research Centre, Hotchkiss Brain Institute (M.T.F), University of Calgary, Alberta, Canada; Cerebrovascular Program, Vanderbilt University Medical Center, Nashville, TN (M.G.); Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University School of Medicine, CA (M.G.L.); Department of Neurology and Stroke Center, Oregon Health & Science University, Portland (H.L.); and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (L.S.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018715DOI Listing
January 2018

Multiphase CT Angiography Improves Prediction of Intracerebral Hemorrhage Expansion.

Radiology 2017 12 3;285(3):932-940. Epub 2017 Jul 3.

From the Stroke Unit, Departments of Neurology (D.R.L., N.R.V., J.M.J., S.B., M.M, J.P., M. Rubiera, M. Ribo, C.A.M.) and Neuroradiology (P.C., A.T.), Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Ps Vall d'Hebron 119, 08035 Barcelona, Spain; and Calgary Stroke Program, Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.G.).

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http://dx.doi.org/10.1148/radiol.2017162839DOI Listing
December 2017

Minimal sufficient balance randomization for sequential randomized controlled trial designs: results from the ESCAPE trial.

Trials 2017 Nov 2;18(1):516. Epub 2017 Nov 2.

Department of Community Health Sciences and O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1186/s13063-017-2264-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667454PMC
November 2017

Approaches to the field recognition of potential thrombectomy candidates.

Int J Stroke 2017 10 3;12(7):698-707. Epub 2017 Aug 3.

1 Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1177/1747493017724585DOI Listing
October 2017

Collateral Scoring on CT Angiogram Must Evaluate Phase and Regional Pattern.

Can J Neurol Sci 2017 Sep;44(5):503-507

1Department of Clinical Neurosciences,Calgary Stroke Program,Hotchkiss Brain Institute,University of Calgary,Canada.

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http://dx.doi.org/10.1017/cjn.2017.53DOI Listing
September 2017

Neurons Over Nephrons: Systematic Review and Meta-Analysis of Contrast-Induced Nephropathy in Patients With Acute Stroke.

Stroke 2017 07 5;48(7):1862-1868. Epub 2017 Jun 5.

From the Department of Radiology (W.B., R.J.M., J.S.M., D.F.K.), Department of Neurosurgery (W.B., D.F.K.), Division of Preventive Medicine and Knowledge and Evaluation Research Unit (M.H.M.), and Department of Neurology (A.A.R.), Mayo Clinic, Rochester, MN; and Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Foothills Hospital, Alberta, Canada (A.M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016771DOI Listing
July 2017

Low- Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy: The ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study).

Stroke 2017 07 15;48(7):1877-1883. Epub 2017 Jun 15.

From the Department of Cardiovascular Sciences, National Institute for Health Research Biomedical Research Unit, University of Leicester, (T.G.R.); George Institute for Global Health, Neurological and Mental Health Division (X.W., H.A., L.B., R.I.L., M.W., J.C., C.S.A.), Faculty of Medicine, University of New South Wales (X.W., H.A., L.B., M.W., J.C., C.S.A.), and Department of Geriatric Medicine, Westmead Clinical School (R.I.L.), University of Sydney, Australia; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, United Kingdom (P.M.B.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati Neuroscience Institute (J.P.B.); Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Canada (A.M.D.); Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia (G.A.D.); Department of Neurology, Asan Medical Center, University of Ulsan, Seoul, Korea (J.S.K.); Department of Neurology and Psychiatry, Clinica Alemana de Santiago, Facultad de Medicina, Clinica Alemana Universidad del Desarrollo, Chile (P.M.L., V.V.O.); Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Santiago (P.M.L.); Department of Neurology, Stroke Center, Linkou Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan (T.-H.L.); Stroke Division of Neurology Service, Hospital de Clinicas de Porto Alegre, University of Rio Grande do Sul, Brazil (S.C.O.M.); Department of Neurology, Christian Medical College, Ludhiana, Punjab, India (J.D.P.); Department of Neurology, John Hunter Hospital, University of Newcastle, Australia (M.W.P.); Department of Neurosciences and Behavioral Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Brazil (O.M.P.-N.); Uo Neurologia, USL Umbria 1, Sedi di Citta di Castello e Branca, Italy (S.R.); Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (S.S.); Yong Loo Lin School of Medicine, National University of Singapore (V.K.S.); Division of Neurology, National University Hospital, Singapore (V.K.S.); Department of Cerebrovascular Disease, 115 People's Hospital, Ho Chi Minh City, Vietnam (T.H.N.); The Shanghai Institute for Hypertension, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, China (J.-G.W.); Department of Epidemiology, Johns Hopkins University, Baltimore, MD (M.W.); George Institute for Global Health, University of Oxford, United Kingdom (M.W.); Department of Neurology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia (C.S.A.); and The George Institute China, Peking University Health Sciences Center, Beijing (C.S.A.).

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July 2017

Use of Noncontrast Computed Tomography and Computed Tomographic Perfusion in Predicting Intracerebral Hemorrhage After Intravenous Alteplase Therapy.

Stroke 2017 06 26;48(6):1548-1553. Epub 2017 Apr 26.

From the Calgary Stroke Program, Department of Clinical Neurosciences (P.P., C.D.d., M.N., F.S.A.-A., C.M., L.H., M.D.H., A.M.D., T.T.S., M.G., B.K.M.), Department of Radiology (C.D.d., M.D.H., A.M.D., M.G., T.-Y.L., B.K.M.), Department of Community Health Sciences (P.P., M.D.H., T.T.S., B.K.M.), and Biomedical Engineering Graduate Program (M.E.B.), University of Calgary, Alberta; Hotchkiss Brain Institute, Calgary, Alberta (P.P., M.D.H., A.M.D., T.T.S., M.G., B.K.M.); Seaman Family Research Centre, Foothills Medical Centre, Calgary, Alberta (C.B., C.D.d., M.N., M.E.B., L.H., M.D.H., A.M.D., M.G., B.K.M.); Department of Neuroradiology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario (R.I.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Lawson Health Research Institute and Robarts Research Institute, London, Ontario (A.V.K., T.-Y.L.); Department of Clinical Neurosciences, University of Western Ontario (A.V.K.); Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia (F.S.A.-A.); and Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.).

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June 2017

Association of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes.

BMC Neurol 2017 May 19;17(1):101. Epub 2017 May 19.

Department of Neurology, Ajou University School of Medicine, Ajou University Medical Center, San 5, Woncheon-dong, Yeongtong-gu, Suwon, Kyungki-do, 443-721, South Korea.

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http://dx.doi.org/10.1186/s12883-017-0865-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438529PMC
May 2017

Vessel Patency at 24 Hours and Its Relationship With Clinical Outcomes and Infarct Volume in REVASCAT Trial (Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset).

Stroke 2017 04 14;48(4):983-989. Epub 2017 Mar 14.

From the Stroke Unit and Interventional Neuroradiology Section, Department of Neurosciences, Hospital Germans Trias, Universitat Autònoma de Barcelona, Spain (M.M., S.R., N.P.d.l.O., M.H., A.D.); Stroke Unit, Neurology Department, Hospital de Bellvitge, L'Hospitalet de Llobregat (Barcelona), Spain (H.Q., P.C.); Stroke Unit, Neurology Department, Hospital Clínic, Barcelona, Spain (A.R., L.L.); Radiology Department (A.T.) and Stroke Unit, Neurology Department (M.R.), Hospital Vall d'Hebron, Barcelona, Spain; Calgary Stroke Program, Hotchkiss Brain Institute, Department of Clinical Neurosciences and Radiology, University of Calgary (P.M., F.A.-A., Z.A., A.M.D.); and Stroke Institute, Department of Neurology, University of Pittsburgh Medical Center, PA (T.J.).

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April 2017

Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke.

Stroke 2017 04 14;48(4):939-945. Epub 2017 Mar 14.

From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).

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April 2017

Defining the Role of the Stroke Physician During Endovascular Therapy of Acute Ischemic Stroke.

Stroke 2017 03 31;48(3):805-807. Epub 2017 Jan 31.

From the Division of Neurology, Department of Medicine (G.S.) and Department of Medical Imaging (C.L.), Ottawa Hospital, University of Ottawa, Ontario, Canada; Department of Neurosciences (A.Y.P.) and Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal, Québec, Canada; University of Pittsburgh Medical Centre, PA (T.G.J.); Department of Geriatric and Stroke Medicine, Royal College of Surgeons in Ireland, Dublin (D.W.); Beaumont Hospital, Dublin, Ireland (D.W., J.T.); Erlanger Medical Centre, Chattanooga, TN (B.W.B., T.D.); Swedish Medical Centre, Englewood, CO (D.F.F., C.F.); Division of Neurology, Department of Medicine (A.S.) and Department of Radiology (J.L.R.), University of Alberta, Edmonton, Canada; and Department of Clinical Neurosciences (B.K.M., A.M.D., M.D.H.), Department of Medicine (A.M.D., M.D.H.), Department of Radiology (A.M.D., M.G., M.D.H.), and Department of Community Health Sciences (A.M.D., M.D.H.), Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.

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March 2017

Improving reperfusion time within the ESCAPE Endovascular Clinical Trial.

Eur Stroke J 2017 Mar 30;2(1):64-69. Epub 2016 Nov 30.

Departments of Clinical Neurosciences, Medicine, Radiology and Community Health Sciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Canada.

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http://dx.doi.org/10.1177/2396987316681176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453179PMC
March 2017

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke.

Stroke 2017 02 22;48(2):353-360. Epub 2016 Dec 22.

From the Division of Neuroimaging Sciences (G.M., A.J.F., R.J.S., E.S., J.P., J.M.W.) and Division of Clinical Neurosciences (D.P., P.A.G.S.), University of Edinburgh, United Kingdom; Department of Neuroradiology, Dresden University Stroke Centre, Germany (R.v.K.); Stroke Center, Sacro Cuore-Don Calabria Hospital, Verona, Italy (A.A.); Stroke Research Group, Newcastle upon Tyne, United Kingdom (P.M.W.); National Hospital for Neurology and Neurosurgery, London, United Kingdom (M.E.A.); Neurovascular Research Group, Royal Melbourne Hospital, Australia (B.Y.); Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Canada (A.M.D.); and Westmead Hospital Clinical School and The George Institute for Global Health, University of Sydney, Australia (R.I.L.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266422PMC
February 2017

Distinctive patterns on CT angiography characterize acute internal carotid artery occlusion subtypes.

Medicine (Baltimore) 2017 Feb;96(5):e5722

aDepartment of Neurology, School of Medicine, Ajou University, Suwon, South Korea bCalgary Stroke Program, Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293413PMC
February 2017

Venous imaging-based biomarkers in acute ischaemic stroke.

J Neurol Neurosurg Psychiatry 2017 Jan 2;88(1):62-69. Epub 2016 Nov 2.

Institute of Diagnostic Imaging (IDI)-Research Unit (IDIR), Girona, Spain.

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January 2017

Early Trajectory of Stroke Severity Predicts Long-Term Functional Outcomes in Ischemic Stroke Subjects: Results From the ESCAPE Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times).

Stroke 2017 01 6;48(1):105-110. Epub 2016 Dec 6.

From the Department of Community Health Sciences and O'Brien Institute for Public Health (T.T.S., B.K.M., M.W.L., M.D.H.), Department of Clinical Neurosciences (T.T.S., B.K.M., M.W., A.M.D., M.G., M.D.H.), Hotchkiss Brain Institute (T.T.S., B.K.M., A.M.D., M.G., M.D.H.), Department of Radiology (B.K.M., A.M.D., M.G., M.D.H.), Clinical Research Unit (T.T.S., B.K.M., M.W.L., M.D.H.), Department of Physiology and Pharmacology (O.L.), Cumming School of Medicine, University of Calgary, Alberta, Canada; Division of Neurology, University of Alberta, Edmonton, Alberta, Canada (A.S.); Royal College of Physicians in Ireland and Beaumont Hospital, Dublin, Ireland (D.W.); Department of Clinical Neurosciences, Universite de Montreal and Hopital Notre Dame, Quebec, Canada (A.Y.P.); University of Pittsburgh Medical Centre, PA (T.G.J.); University Health Network and Toronto Western Hospital, Ontario, Canada (L.K.C.); Erlanger Medical Center, Chattanooga, TN (T.D.); University of Ottawa Hospital, Ontario, Canada (D.D.); and Swedish Medical Centre, Englewood, CO (C.F.).

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January 2017

Improving Door-to-Needle Times for Acute Ischemic Stroke: Effect of Rapid Patient Registration, Moving Directly to Computed Tomography, and Giving Alteplase at the Computed Tomography Scanner.

Circ Cardiovasc Qual Outcomes 2017 01;10(1)

From the Department of Clinical Neurosciences (N.K., A.M.D., M.D.H., E.E.S.) and Department of Community Health Sciences (J.K.H.), Cumming School of Medicine, University of Calgary, Alberta, Canada; Calgary Stroke Program, Alberta Health Services (C.S., A.M.D., M.D.H., C.Z., N.N., D. Knox, E.E.S.) and Department of Emergency Medicine (D. Kashayp, E.B., E.L.), Foothills Medical Centre, Calgary, Alberta, Canada; Emergency Medical Services, Alterta Health Services, Calgary, Alberta, Canada (R.L.V.); and Hotchkiss Brain Institute (A.M.D., M.D.H., E.E.S.), University of Calgary, Calgary, Alberta, Canada.

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January 2017

Infarct in a New Territory After Treatment Administration in the ESCAPE Randomized Controlled Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times).

Stroke 2016 12 10;47(12):2993-2998. Epub 2016 Nov 10.

From the Departments of Clinical Neurosciences and Radiology (A.G., F.S.A.-A., F.S., Z.A., S.B.C., P.A.B., A.M.D., M.E., M.D.H., M.G., B.K.M.), Departments of Community Health Sciences and Medicine (S.B.C., T.S., M.D.H., B.K.M.), and Hotchkiss Brain Institute (S.B.C., P.A.B., A.M.D., M.D.H., M.G., B.K.M.), Cumming School of Medicine, University of Calgary, Alberta, Canada; Division of Neuroradiology (T.K.), and Division of Neurology, Department of Medicine (L.K.C.), UHN, Toronto Western Hospital, Ontario, Canada; Departments of Radiology (J.L.R.) and Medicine (Neurology) (K.B.), University of Alberta, Edmonton, Canada; Departments of Neuroradiology (J. Thornton) and Geriatric and Stroke Medicine (P.K.), Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), CHUM, University of Montreal, Quebec, Canada; Department of Neurology, University of Pittsburgh Medical Center, PA (T.G.J.); Acute Stroke Services (T.D.) and Department of Radiology, Erlanger Hospital (B.W.B.), University of Tennessee, Chattanooga; Colorado Neurological Institute, Englewood (D.F.F.); Department of Neurointerventional Care, The Neurosciences Institute, Abington Memorial Hospital, Abington, PA (H.C.); Department of Diagnostic and Interventional Neuroradiology (D.T.) and Department of Neurology and Neurosurgery (J. Teitelbaum), Montreal Neurological Institute, McGill University, Quebec, Canada; Department of Radiology, The Ottawa Hospital, University of Ottawa, Ontario, Canada (C.L.); Department of Clinical Neurological Sciences, London Health Sciences Center, Western University, Ontario, Canada (J.M.); Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada (S.J.P.); Department of Neurology, Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea (O.Y.B.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.M.); and the Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom (A.G.).

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December 2016

Visual aid tool to improve decision making in acute stroke care.

Int J Stroke 2016 10 20;11(8):868-873. Epub 2016 Aug 20.

3 Foothills Medical Center, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada.

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October 2016

Imaging Predictors for Atherosclerosis-Related Intracranial Large Artery Occlusions in Acute Anterior Circulation Stroke.

J Stroke 2016 Sep 4;18(3):352-354. Epub 2016 Aug 4.

Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.

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http://dx.doi.org/10.5853/jos.2016.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066434PMC
September 2016

Multiphase CT angiography increases detection of anterior circulation intracranial occlusion.

Neurology 2016 Aug 6;87(6):609-16. Epub 2016 Jul 6.

From the Department of Clinical Neurosciences (A.Y.X.Y., C.Z., P.A.R., M.N., M.G., B.K.M., A.M.D., S.B.C., M.D.H.), Community Health Sciences (A.Y.X.Y., J.K.H., B.K.M., S.B.C., M.D.H.), Department of Radiology (Z.A., M.G., B.K.M., A.M.D., S.B.C., M.D.H.), and Hotchkiss Brain Institute (M.G., B.K.M., A.M.D., S.B.C., M.D.H.), University of Calgary, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977373PMC
August 2016