Andrew D Paterson

Andrew D Paterson

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Andrew D Paterson

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Fast and Accurate Shared Segment Detection and Relatedness Estimation in Un-phased Genetic Data via TRUFFLE.

Am J Hum Genet 2019 Jul 6;105(1):78-88. Epub 2019 Jun 6.

Department of Statistical Sciences, University of Toronto, Toronto, ON M5S 3G3, Canada; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, ON M5T 3M7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612710PMC
July 2019

gpart: human genome partitioning and visualization of high-density SNP data by identifying haplotype blocks.

Bioinformatics 2019 May 9. Epub 2019 May 9.

Department of Mathematics Education, Seoul National University, Seoul.

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http://dx.doi.org/10.1093/bioinformatics/btz308DOI Listing
May 2019

Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease and mortality in the general population.

Diabetologia 2019 02 21;62(2):269-280. Epub 2018 Nov 21.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, HPC AA31 9700 RB, Groningen, the Netherlands.

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http://dx.doi.org/10.1007/s00125-018-4769-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323092PMC
February 2019

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Diabetes 2019 02 28;68(2):441-456. Epub 2018 Nov 28.

Massachusetts Eye and Ear Department of Ophthalmology, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/db18-0567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341299PMC
February 2019

Prevalence Estimates of Polycystic Kidney and Liver Disease by Population Sequencing.

J Am Soc Nephrol 2018 Oct 22;29(10):2593-2600. Epub 2018 Aug 22.

Division of Nephrology, University Health Network, University of Toronto, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1681/ASN.2018050493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171271PMC
October 2018

Phenotypic and genetic analysis of an adult cohort with extreme obesity.

Int J Obes (Lond) 2018 Sep 21. Epub 2018 Sep 21.

Department of Medicine and Endocrinology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41366-018-0209-8DOI Listing
September 2018

Evidence of batch effects masking treatment effect in GAW20 methylation data.

BMC Proc 2018 17;12(Suppl 9):32. Epub 2018 Sep 17.

2Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, 686 Bay St., Toronto, ON M5G 0A4 Canada.

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http://dx.doi.org/10.1186/s12919-018-0129-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157182PMC
September 2018

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

Diabetes 2018 07 27;67(7):1414-1427. Epub 2018 Apr 27.

Wellcome Centre Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db17-0914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014557PMC
July 2018

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Authors:
Milly S Tedja Robert Wojciechowski Pirro G Hysi Nicholas Eriksson Nicholas A Furlotte Virginie J M Verhoeven Adriana I Iglesias Magda A Meester-Smoor Stuart W Tompson Qiao Fan Anthony P Khawaja Ching-Yu Cheng René Höhn Kenji Yamashiro Adam Wenocur Clare Grazal Toomas Haller Andres Metspalu Juho Wedenoja Jost B Jonas Ya Xing Wang Jing Xie Paul Mitchell Paul J Foster Barbara E K Klein Ronald Klein Andrew D Paterson S Mohsen Hosseini Rupal L Shah Cathy Williams Yik Ying Teo Yih Chung Tham Preeti Gupta Wanting Zhao Yuan Shi Woei-Yuh Saw E-Shyong Tai Xue Ling Sim Jennifer E Huffman Ozren Polašek Caroline Hayward Goran Bencic Igor Rudan James F Wilson Peter K Joshi Akitaka Tsujikawa Fumihiko Matsuda Kristina N Whisenhunt Tanja Zeller Peter J van der Spek Roxanna Haak Hanne Meijers-Heijboer Elisabeth M van Leeuwen Sudha K Iyengar Jonathan H Lass Albert Hofman Fernando Rivadeneira André G Uitterlinden Johannes R Vingerling Terho Lehtimäki Olli T Raitakari Ginevra Biino Maria Pina Concas Tae-Hwi Schwantes-An Robert P Igo Gabriel Cuellar-Partida Nicholas G Martin Jamie E Craig Puya Gharahkhani Katie M Williams Abhishek Nag Jugnoo S Rahi Phillippa M Cumberland Cécile Delcourt Céline Bellenguez Janina S Ried Arthur A Bergen Thomas Meitinger Christian Gieger Tien Yin Wong Alex W Hewitt David A Mackey Claire L Simpson Norbert Pfeiffer Olavi Pärssinen Paul N Baird Veronique Vitart Najaf Amin Cornelia M van Duijn Joan E Bailey-Wilson Terri L Young Seang-Mei Saw Dwight Stambolian Stuart MacGregor Jeremy A Guggenheim Joyce Y Tung Christopher J Hammond Caroline C W Klaver

Nat Genet 2018 06 28;50(6):834-848. Epub 2018 May 28.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.nature.com/articles/s41588-018-0127-7
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http://dx.doi.org/10.1038/s41588-018-0127-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980758PMC
June 2018

Model-Free Linkage Analysis of a Binary Trait.

Methods Mol Biol 2017 ;1666:343-373

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray St., Box 18, Toronto, ON, Canada, M5T 3L9.

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http://dx.doi.org/10.1007/978-1-4939-7274-6_17DOI Listing
May 2018

X-Linked Glomerulopathy Due to COL4A5 Founder Variant.

Am J Kidney Dis 2018 03 1;71(3):441-445. Epub 2017 Dec 1.

Division of Nephrology, University Health Network, Toronto, Canada; Toronto General Research Institute, Toronto General Hospital, Toronto, Canada; Department of Medicine, University of Toronto, Toronto, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S02726386173096
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http://dx.doi.org/10.1053/j.ajkd.2017.09.005DOI Listing
March 2018

The origins of breast cancer associated with mammographic density: a testable biological hypothesis.

Breast Cancer Res 2018 03 7;20(1):17. Epub 2018 Mar 7.

Genetics and Genome Biology, Hospital for Sick Children Research Institute, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s13058-018-0941-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842598PMC
March 2018

Genetic determinants of impaired awareness of hypoglycemia in type 1 diabetes.

Pharmacogenet Genomics 2017 Sep;27(9):323-328

Departments of aPharmacology and Toxicology bInternal Medicine cHuman Genetics, Radboud University Medical Center, Nijmegen, The Netherlands dGenetics and Genome Biology Program, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/FPC.0000000000000295DOI Listing
September 2017

HbA1c for type 2 diabetes diagnosis in Africans and African Americans: Personalized medicine NOW!

PLoS Med 2017 Sep 12;14(9):e1002384. Epub 2017 Sep 12.

Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pmed.1002384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595287PMC
September 2017

Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose.

PLoS One 2016 10;11(8):e0160504. Epub 2016 Aug 10.

Departments of Medicine and Pharmacology Case Western Reserve University, Cleveland, Ohio, United States of America, and the Veterans Administration Medical Center Research Service 151, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160504PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979894PMC
August 2017

Bayesian latent variable models for hierarchical clustered count outcomes with repeated measures in microbiome studies.

Genet Epidemiol 2017 Apr 22;41(3):221-232. Epub 2017 Jan 22.

Dalla Lana School of Public Health, University of Toronto, ON, M5T 3M7, Canada.

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http://dx.doi.org/10.1002/gepi.22031DOI Listing
April 2017

Novel 25 kb Deletion of MERTK Causes Retinitis Pigmentosa With Severe Progression.

Invest Ophthalmol Vis Sci 2017 03;58(3):1736-1742

Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.

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http://dx.doi.org/10.1167/iovs.16-20864DOI Listing
March 2017

Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure.

Genet Epidemiol 2017 Feb 25;41(2):108-121. Epub 2016 Nov 25.

Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/gepi.22024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245123PMC
February 2017

Albuminuria Changes and Cardiovascular and Renal Outcomes in Type 1 Diabetes: The DCCT/EDIC Study.

Clin J Am Soc Nephrol 2016 11 24;11(11):1969-1977. Epub 2016 Oct 24.

Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2215/CJN.02870316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108190PMC
November 2016

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.

J Clin Oncol 2016 Oct;34(30):3697-3704

Nardin Samuel, Gavin Wilson, James Tran, Meredith Irwin, Rosanna Weksberg, Thomas J. Hudson, and David Malkin, University of Toronto; Nardin Samuel, Badr Id Said, Youliang Lou, Weili Li, Ana Novokmet, James Tran, Sanaa Choufani, Marc Remke, Vijay Ramaswamy, Florence M.G. Cavalli, Michael D. Taylor, Uri Tabori, Meredith Irwin, Rosanna Weksberg, Jonathan D. Wasserman, Andrew D. Paterson, and David Malkin, The Hospital for Sick Children; Nardin Samuel, Gavin Wilson, Mathieu Lemire, and Thomas J. Hudson, Ontario Institute for Cancer Research; Christine Elser, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Diana Merino, National Institutes of Health, Bethesda, MD; Kim E. Nichols, St Jude Children's Research Hospital, Memphis, TN; Jonathan L. Finlay, Nationwide Children's Hospital, Columbus, OH; Lynn Meister, Joe DiMaggio Children's Hospital, Hollywood, FL; Jordan R. Hansford, Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia; and Maria Isabel W. Achatz, Hospital AC Camargo, São Paulo, Brazil.

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http://dx.doi.org/10.1200/JCO.2016.67.6940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366343PMC
October 2016

Factors associated with heterogeneity in microarray gene expression in peripheral blood mononuclear cells from large pedigrees.

BMC Proc 2016 18;10(Suppl 7):91-95. Epub 2016 Oct 18.

Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4 Canada ; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5G 0A4 Canada.

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http://dx.doi.org/10.1186/s12919-016-0011-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133527PMC
October 2016

Identity-by-descent mapping for diastolic blood pressure in unrelated Mexican Americans.

BMC Proc 2016 18;10(Suppl 7):263-267. Epub 2016 Oct 18.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON M5G 0A4 Canada ; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5G 0A4 Canada.

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http://dx.doi.org/10.1186/s12919-016-0041-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133517PMC
October 2016

Lifestyle and clinical determinants of skin autofluorescence in a population-based cohort study.

Eur J Clin Invest 2016 May 15;46(5):481-90. Epub 2016 Apr 15.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/eci.12627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111733PMC
May 2016

Parameter Expanded Algorithms for Bayesian Latent Variable Modeling of Genetic Pleiotropy Data.

J Comput Graph Stat 2016 10;25(2):405-425. Epub 2016 May 10.

Program in Genetics and Genomic Biology, Hospital for Sick Children, and Dalla Lana School of Public Health, University of Toronto, Toronto,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064966PMC
http://dx.doi.org/10.1080/10618600.2014.988337DOI Listing
May 2016

Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes.

Diabetes 2016 04 30;65(4):1022-30. Epub 2015 Dec 30.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Diabetes and Obesity Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland Baker IDI Heart and Diabetes Institute, Melbourne, Australia

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http://diabetes.diabetesjournals.org/content/early/2015/12/1
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db15
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http://dx.doi.org/10.2337/db15-1247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806664PMC
April 2016

Assessment and Selection of Competing Models for Zero-Inflated Microbiome Data.

PLoS One 2015 6;10(7):e0129606. Epub 2015 Jul 6.

Dalla Lana School of Public Health, University of Toronto, ON, M5T 3M7, Canada; Department of Biostatistics, Princess Margaret Hospital, 610 University Avenue, Toronto, ON, M5G 2M9, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129606PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493133PMC
March 2016

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

Authors:
Alexander Teumer Adrienne Tin Rossella Sorice Mathias Gorski Nan Cher Yeo Audrey Y Chu Man Li Yong Li Vladan Mijatovic Yi-An Ko Daniel Taliun Alessandro Luciani Ming-Huei Chen Qiong Yang Meredith C Foster Matthias Olden Linda T Hiraki Bamidele O Tayo Christian Fuchsberger Aida Karina Dieffenbach Alan R Shuldiner Albert V Smith Allison M Zappa Antonio Lupo Barbara Kollerits Belen Ponte Bénédicte Stengel Bernhard K Krämer Bernhard Paulweber Braxton D Mitchell Caroline Hayward Catherine Helmer Christa Meisinger Christian Gieger Christian M Shaffer Christian Müller Claudia Langenberg Daniel Ackermann David Siscovick Eric Boerwinkle Florian Kronenberg Georg B Ehret Georg Homuth Gerard Waeber Gerjan Navis Giovanni Gambaro Giovanni Malerba Gudny Eiriksdottir Guo Li H Erich Wichmann Harald Grallert Henri Wallaschofski Henry Völzke Herrmann Brenner Holly Kramer I Mateo Leach Igor Rudan Hans L Hillege Jacques S Beckmann Jean Charles Lambert Jian'an Luan Jing Hua Zhao John Chalmers Josef Coresh Joshua C Denny Katja Butterbach Lenore J Launer Luigi Ferrucci Lyudmyla Kedenko Margot Haun Marie Metzger Mark Woodward Matthew J Hoffman Matthias Nauck Melanie Waldenberger Menno Pruijm Murielle Bochud Myriam Rheinberger Niek Verweij Nicholas J Wareham Nicole Endlich Nicole Soranzo Ozren Polasek Pim van der Harst Peter Paul Pramstaller Peter Vollenweider Philipp S Wild Ron T Gansevoort Rainer Rettig Reiner Biffar Robert J Carroll Ronit Katz Ruth J F Loos Shih-Jen Hwang Stefan Coassin Sven Bergmann Sylvia E Rosas Sylvia Stracke Tamara B Harris Tanguy Corre Tanja Zeller Thomas Illig Thor Aspelund Toshiko Tanaka Uwe Lendeckel Uwe Völker Vilmundur Gudnason Vincent Chouraki Wolfgang Koenig Zoltan Kutalik Jeffrey R O'Connell Afshin Parsa Iris M Heid Andrew D Paterson Ian H de Boer Olivier Devuyst Jozef Lazar Karlhans Endlich Katalin Susztak Johanne Tremblay Pavel Hamet Howard J Jacob Carsten A Böger Caroline S Fox Cristian Pattaro Anna Köttgen

Diabetes 2016 Mar 2;65(3):803-17. Epub 2015 Dec 2.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Renal Division, Medical Center, University of Freiburg, Freiburg, Germany

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http://diabetes.diabetesjournals.org/content/early/2015/11/2
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db15
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http://dx.doi.org/10.2337/db15-1313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764151PMC
March 2016

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Authors:
Qiao Fan Virginie J M Verhoeven Robert Wojciechowski Veluchamy A Barathi Pirro G Hysi Jeremy A Guggenheim René Höhn Veronique Vitart Anthony P Khawaja Kenji Yamashiro S Mohsen Hosseini Terho Lehtimäki Yi Lu Toomas Haller Jing Xie Cécile Delcourt Mario Pirastu Juho Wedenoja Puya Gharahkhani Cristina Venturini Masahiro Miyake Alex W Hewitt Xiaobo Guo Johanna Mazur Jenifer E Huffman Katie M Williams Ozren Polasek Harry Campbell Igor Rudan Zoran Vatavuk James F Wilson Peter K Joshi George McMahon Beate St Pourcain David M Evans Claire L Simpson Tae-Hwi Schwantes-An Robert P Igo Alireza Mirshahi Audrey Cougnard-Gregoire Céline Bellenguez Maria Blettner Olli Raitakari Mika Kähönen Ilkka Seppala Tanja Zeller Thomas Meitinger Janina S Ried Christian Gieger Laura Portas Elisabeth M van Leeuwen Najaf Amin André G Uitterlinden Fernando Rivadeneira Albert Hofman Johannes R Vingerling Ya Xing Wang Xu Wang Eileen Tai-Hui Boh M Kamran Ikram Charumathi Sabanayagam Preeti Gupta Vincent Tan Lei Zhou Candice E H Ho Wan'e Lim Roger W Beuerman Rosalynn Siantar E-Shyong Tai Eranga Vithana Evelin Mihailov Chiea-Chuen Khor Caroline Hayward Robert N Luben Paul J Foster Barbara E K Klein Ronald Klein Hoi-Suen Wong Paul Mitchell Andres Metspalu Tin Aung Terri L Young Mingguang He Olavi Pärssinen Cornelia M van Duijn Jie Jin Wang Cathy Williams Jost B Jonas Yik-Ying Teo David A Mackey Konrad Oexle Nagahisa Yoshimura Andrew D Paterson Norbert Pfeiffer Tien-Yin Wong Paul N Baird Dwight Stambolian Joan E Bailey Wilson Ching-Yu Cheng Christopher J Hammond Caroline C W Klaver Seang-Mei Saw Jugnoo S Rahi Jean-François Korobelnik John P Kemp Nicholas J Timpson George Davey Smith Jamie E Craig Kathryn P Burdon Rhys D Fogarty Sudha K Iyengar Emily Chew Sarayut Janmahasatian Nicholas G Martin Stuart MacGregor Liang Xu Maria Schache Vinay Nangia Songhomitra Panda-Jonas Alan F Wright Jeremy R Fondran Jonathan H Lass Sheng Feng Jing Hua Zhao Kay-Tee Khaw Nick J Wareham Taina Rantanen Jaakko Kaprio Chi Pui Pang Li Jia Chen Pancy O Tam Vishal Jhanji Alvin L Young Angela Döring Leslie J Raffel Mary-Frances Cotch Xiaohui Li Shea Ping Yip Maurice K H Yap Ginevra Biino Simona Vaccargiu Maurizio Fossarello Brian Fleck Seyhan Yazar Jan Willem L Tideman Milly Tedja Margaret M Deangelis Margaux Morrison Lindsay Farrer Xiangtian Zhou Wei Chen Nobuhisa Mizuki Akira Meguro Kari Matti Mäkelä

Nat Commun 2016 Mar 29;7:11008. Epub 2016 Mar 29.

Department of Ophthalmology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms11008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820539PMC
March 2016

IBD Genetic Risk Profile in Healthy First-Degree Relatives of Crohn's Disease Patients.

J Crohns Colitis 2016 Feb 28;10(2):209-15. Epub 2015 Oct 28.

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1093/ecco-jcc/jjv197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007582PMC
February 2016

Resampling to Address the Winner's Curse in Genetic Association Analysis of Time to Event.

Genet Epidemiol 2015 Nov 28;39(7):518-28. Epub 2015 Sep 28.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.

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http://dx.doi.org/10.1002/gepi.21920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609263PMC
November 2015

Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes.

Diabetes Technol Ther 2015 Oct 20;17(10):726-34. Epub 2015 Jul 20.

1 Program in Genetics and Genome Biology, Hospital for Sick Children , Toronto, Ontario, Canada .

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http://dx.doi.org/10.1089/dia.2015.0017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575521PMC
October 2015

GRIN1 polymorphisms do not affect susceptibility or phenotype in NMDA receptor encephalitis.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 24;2(5):e153. Epub 2015 Sep 24.

Department of Medicine (G.S.D., D.M.A.), Division of Neurology, and Dalla Lana School of Public Health (A.D.P.), University of Toronto, Ontario, Canada; Department of Neurology, Charité-Universitätsmedizin Berlin, and German Center for Neurodegenerative Diseases (DZNE) (H.P.), Berlin, Germany; Department of Rheumatology, Alberta Children's Hospital, and Research Institute (S.M.B.), University of Calgary, Alberta, Canada; The Centre for Applied Genomics (T.A.P., A.D.P.), The Hospital for Sick Children, Toronto, Ontario, Canada; and University Health Network (D.M.A.), Toronto Western Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1212/NXI.0000000000000153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582904PMC
October 2015

A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways.

Am J Hum Genet 2015 Jul;97(1):125-38

Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada; Department of Statistical Sciences, University of Toronto, Toronto, ON M5S 3G3, Canada. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(15)00201-3.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971500201
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http://dx.doi.org/10.1016/j.ajhg.2015.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572492PMC
July 2015

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods.

BMC Genomics 2015 May 22;16:405. Epub 2015 May 22.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1186/s12864-015-1616-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440290PMC
May 2015

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.

Hum Genet 2015 Feb 4;134(2):131-46. Epub 2014 Nov 4.

National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive Suite 1200, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1007/s00439-014-1500-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291519PMC
February 2015

The association of previously reported polymorphisms for microvascular complications in a meta-analysis of diabetic retinopathy.

Hum Genet 2015 Feb 7;134(2):247-57. Epub 2014 Dec 7.

Genetics and Genome Biology Program, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Rm 12.9835, 686 Bay Street, Toronto, ON, M5G 0A4, Canada,

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http://dx.doi.org/10.1007/s00439-014-1517-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291513PMC
February 2015

A functional polymorphism of Ptpn22 is associated with type 1 diabetes in the BioBreeding rat.

J Immunol 2015 Jan 12;194(2):615-29. Epub 2014 Dec 12.

Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario M4N 3M5, Canada;

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http://dx.doi.org/10.4049/jimmunol.1302689DOI Listing
January 2015

OTX2 mutations cause autosomal dominant pattern dystrophy of the retinal pigment epithelium.

J Med Genet 2014 Dec 7;51(12):797-805. Epub 2014 Oct 7.

Department of Ophthalmology, The Hospital for Sick Children, Toronto, Ontario, Canada Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/jmedgenet-2014-102620DOI Listing
December 2014

Dynamic pathway analysis of genes associated with blood pressure using whole genome sequence data.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S106. Epub 2014 Jun 17.

The Centre for Applied Genomics, The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 0A4, Canada ; Program in Genetics and Genome Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON, M5G 0A4, Canada ; Dalla Lana School of Public Health, University of Toronto, Health Sciences Building, 155 College St, Toronto, ON, M5T 3M7, Canada.

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December 2014

Genetic Analysis Workshop 18 single-nucleotide variant prioritization based on protein impact, sequence conservation, and gene annotation.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S11. Epub 2014 Jun 17.

The Centre for Applied Genomics, The Hospital for Sick Children, 101 College Street, M5G 1L7 Toronto, ON, Canada ; Program in Genetics and Genome Biology, The Hospital for Sick Children, 101 College Street, M5G 1L7 Toronto, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143669PMC
December 2014

Using a Bayesian latent variable approach to detect pleiotropy in the Genetic Analysis Workshop 18 data.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S77. Epub 2014 Jun 17.

Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Ontario M5S 3G3, Canada ; Department of Statistical Sciences, University of Toronto, Toronto, Ontario M5S 3G3, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143687PMC
December 2014

Evaluation of gene-based association tests for analyzing rare variants using Genetic Analysis Workshop 18 data.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S9. Epub 2014 Jun 17.

Department of Statistical Sciences, University of Toronto, Toronto, Ontario M5S 3G3, Canada ; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Ontario M5S 3G3, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143759PMC
December 2014

Drinking from the Holy Grail: analysis of whole-genome sequencing from the Genetic Analysis Workshop 18.

Genet Epidemiol 2014 Sep;38 Suppl 1:S1-4

Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada; Divisions of Epidemiology and Biostatistics, Dalla Lana School of Public Health, Department of Psychiatry, Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

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September 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes.

Hum Mol Genet 2014 May 30;23(10):2752-68. Epub 2013 Dec 30.

The Centre for Applied Genomics.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990173PMC
May 2014

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.

Authors:
Dalila Pinto Elsa Delaby Daniele Merico Mafalda Barbosa Alison Merikangas Lambertus Klei Bhooma Thiruvahindrapuram Xiao Xu Robert Ziman Zhuozhi Wang Jacob A S Vorstman Ann Thompson Regina Regan Marion Pilorge Giovanna Pellecchia Alistair T Pagnamenta Bárbara Oliveira Christian R Marshall Tiago R Magalhaes Jennifer K Lowe Jennifer L Howe Anthony J Griswold John Gilbert Eftichia Duketis Beth A Dombroski Maretha V De Jonge Michael Cuccaro Emily L Crawford Catarina T Correia Judith Conroy Inês C Conceição Andreas G Chiocchetti Jillian P Casey Guiqing Cai Christelle Cabrol Nadia Bolshakova Elena Bacchelli Richard Anney Steven Gallinger Michelle Cotterchio Graham Casey Lonnie Zwaigenbaum Kerstin Wittemeyer Kirsty Wing Simon Wallace Herman van Engeland Ana Tryfon Susanne Thomson Latha Soorya Bernadette Rogé Wendy Roberts Fritz Poustka Susana Mouga Nancy Minshew L Alison McInnes Susan G McGrew Catherine Lord Marion Leboyer Ann S Le Couteur Alexander Kolevzon Patricia Jiménez González Suma Jacob Richard Holt Stephen Guter Jonathan Green Andrew Green Christopher Gillberg Bridget A Fernandez Frederico Duque Richard Delorme Geraldine Dawson Pauline Chaste Cátia Café Sean Brennan Thomas Bourgeron Patrick F Bolton Sven Bölte Raphael Bernier Gillian Baird Anthony J Bailey Evdokia Anagnostou Joana Almeida Ellen M Wijsman Veronica J Vieland Astrid M Vicente Gerard D Schellenberg Margaret Pericak-Vance Andrew D Paterson Jeremy R Parr Guiomar Oliveira John I Nurnberger Anthony P Monaco Elena Maestrini Sabine M Klauck Hakon Hakonarson Jonathan L Haines Daniel H Geschwind Christine M Freitag Susan E Folstein Sean Ennis Hilary Coon Agatino Battaglia Peter Szatmari James S Sutcliffe Joachim Hallmayer Michael Gill Edwin H Cook Joseph D Buxbaum Bernie Devlin Louise Gallagher Catalina Betancur Stephen W Scherer

Am J Hum Genet 2014 May 24;94(5):677-94. Epub 2014 Apr 24.

Program in Genetics and Genome Biology, The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada; McLaughlin Centre, University of Toronto, Toronto, ON M5S 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067558PMC
May 2014

Iddm30 controls pancreatic expression of Ccl11 (Eotaxin) and the Th1/Th2 balance within the insulitic lesions.

J Immunol 2014 Apr 19;192(8):3645-53. Epub 2014 Mar 19.

Sunnybrook Research Institute, Toronto, Ontario M4N 3M5, Canada;

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April 2014

Letter to the editor: expression of concern, reaffirmed.

Age (Dordr) 2014 Feb 24;36(1):479-82. Epub 2013 Aug 24.

Program in Genetics and Genome Biology, The Hospital for Sick Children, TMDT East Tower, Room 15-707, 101 College Street, Toronto, ON, M5G 1L7, Canada,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889910PMC
February 2014

Measurement equivalence of the autism symptom phenotype in children and youth.

J Child Psychol Psychiatry 2013 Dec 24;54(12):1346-55. Epub 2013 Aug 24.

Offord Centre for Child Studies & Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.

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December 2013

Relationship of mode of conception and sex concordance with mortality/morbidity in preterm twins.

Twin Res Hum Genet 2013 Oct 28;16(5):985-93. Epub 2013 Aug 28.

Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada.

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October 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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September 2013

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

Authors:
Ching-Yu Cheng Maria Schache M Kamran Ikram Terri L Young Jeremy A Guggenheim Veronique Vitart Stuart MacGregor Virginie J M Verhoeven Veluchamy A Barathi Jiemin Liao Pirro G Hysi Joan E Bailey-Wilson Beate St Pourcain John P Kemp George McMahon Nicholas J Timpson David M Evans Grant W Montgomery Aniket Mishra Ya Xing Wang Jie Jin Wang Elena Rochtchina Ozren Polasek Alan F Wright Najaf Amin Elisabeth M van Leeuwen James F Wilson Craig E Pennell Cornelia M van Duijn Paulus T V M de Jong Johannes R Vingerling Xin Zhou Peng Chen Ruoying Li Wan-Ting Tay Yingfeng Zheng Merwyn Chew Kathryn P Burdon Jamie E Craig Sudha K Iyengar Robert P Igo Jonathan H Lass Emily Y Chew Toomas Haller Evelin Mihailov Andres Metspalu Juho Wedenoja Claire L Simpson Robert Wojciechowski René Höhn Alireza Mirshahi Tanja Zeller Norbert Pfeiffer Karl J Lackner Thomas Bettecken Thomas Meitinger Konrad Oexle Mario Pirastu Laura Portas Abhishek Nag Katie M Williams Ekaterina Yonova-Doing Ronald Klein Barbara E Klein S Mohsen Hosseini Andrew D Paterson Kari-Matti Makela Terho Lehtimaki Mika Kahonen Olli Raitakari Nagahisa Yoshimura Fumihiko Matsuda Li Jia Chen Chi Pui Pang Shea Ping Yip Maurice K H Yap Akira Meguro Nobuhisa Mizuki Hidetoshi Inoko Paul J Foster Jing Hua Zhao Eranga Vithana E-Shyong Tai Qiao Fan Liang Xu Harry Campbell Brian Fleck Igor Rudan Tin Aung Albert Hofman André G Uitterlinden Goran Bencic Chiea-Chuen Khor Hannah Forward Olavi Pärssinen Paul Mitchell Fernando Rivadeneira Alex W Hewitt Cathy Williams Ben A Oostra Yik-Ying Teo Christopher J Hammond Dwight Stambolian David A Mackey Caroline C W Klaver Tien-Yin Wong Seang-Mei Saw Paul N Baird

Am J Hum Genet 2013 Aug;93(2):264-77

Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore; Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore 169857, Singapore.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772747PMC
August 2013

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

Authors:
Virginie J M Verhoeven Pirro G Hysi Robert Wojciechowski Qiao Fan Jeremy A Guggenheim René Höhn Stuart MacGregor Alex W Hewitt Abhishek Nag Ching-Yu Cheng Ekaterina Yonova-Doing Xin Zhou M Kamran Ikram Gabriëlle H S Buitendijk George McMahon John P Kemp Beate St Pourcain Claire L Simpson Kari-Matti Mäkelä Terho Lehtimäki Mika Kähönen Andrew D Paterson S Mohsen Hosseini Hoi Suen Wong Liang Xu Jost B Jonas Olavi Pärssinen Juho Wedenoja Shea Ping Yip Daniel W H Ho Chi Pui Pang Li Jia Chen Kathryn P Burdon Jamie E Craig Barbara E K Klein Ronald Klein Toomas Haller Andres Metspalu Chiea-Chuen Khor E-Shyong Tai Tin Aung Eranga Vithana Wan-Ting Tay Veluchamy A Barathi Peng Chen Ruoying Li Jiemin Liao Yingfeng Zheng Rick T Ong Angela Döring David M Evans Nicholas J Timpson Annemieke J M H Verkerk Thomas Meitinger Olli Raitakari Felicia Hawthorne Tim D Spector Lennart C Karssen Mario Pirastu Federico Murgia Wei Ang Aniket Mishra Grant W Montgomery Craig E Pennell Phillippa M Cumberland Ioana Cotlarciuc Paul Mitchell Jie Jin Wang Maria Schache Sarayut Janmahasatian Sarayut Janmahasathian Robert P Igo Jonathan H Lass Emily Chew Sudha K Iyengar Theo G M F Gorgels Igor Rudan Caroline Hayward Alan F Wright Ozren Polasek Zoran Vatavuk James F Wilson Brian Fleck Tanja Zeller Alireza Mirshahi Christian Müller André G Uitterlinden Fernando Rivadeneira Johannes R Vingerling Albert Hofman Ben A Oostra Najaf Amin Arthur A B Bergen Yik-Ying Teo Jugnoo S Rahi Veronique Vitart Cathy Williams Paul N Baird Tien-Yin Wong Konrad Oexle Norbert Pfeiffer David A Mackey Terri L Young Cornelia M van Duijn Seang-Mei Saw Joan E Bailey-Wilson Dwight Stambolian Caroline C Klaver Christopher J Hammond

Nat Genet 2013 Mar 10;45(3):314-8. Epub 2013 Feb 10.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740568PMC
March 2013

Individual common variants exert weak effects on the risk for autism spectrum disorders.

Authors:
Richard Anney Lambertus Klei Dalila Pinto Joana Almeida Elena Bacchelli Gillian Baird Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Jillian Casey Judith Conroy Catarina Correia Christina Corsello Emily L Crawford Maretha de Jonge Richard Delorme Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne John Gilbert Christopher Gillberg Joseph T Glessner Andrew Green Jonathan Green Stephen J Guter Elizabeth A Heron Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Suma Jacob Graham P Kenny Cecilia Kim Alexander Kolevzon Vlad Kustanovich Clara M Lajonchere Janine A Lamb Miriam Law-Smith Marion Leboyer Ann Le Couteur Bennett L Leventhal Xiao-Qing Liu Frances Lombard Catherine Lord Linda Lotspeich Sabata C Lund Tiago R Magalhaes Carine Mantoulan Christopher J McDougle Nadine M Melhem Alison Merikangas Nancy J Minshew Ghazala K Mirza Jeff Munson Carolyn Noakes Gudrun Nygren Katerina Papanikolaou Alistair T Pagnamenta Barbara Parrini Tara Paton Andrew Pickles David J Posey Fritz Poustka Jiannis Ragoussis Regina Regan Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Sabine Schlitt Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Vera Stoppioni Nuala Sykes Raffaella Tancredi Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar J A S Vorstman Simon Wallace Kirsty Wing Kerstin Wittemeyer Shawn Wood Danielle Zurawiecki Lonnie Zwaigenbaum Anthony J Bailey Agatino Battaglia Rita M Cantor Hilary Coon Michael L Cuccaro Geraldine Dawson Sean Ennis Christine M Freitag Daniel H Geschwind Jonathan L Haines Sabine M Klauck William M McMahon Elena Maestrini Judith Miller Anthony P Monaco Stanley F Nelson John I Nurnberger Guiomar Oliveira Jeremy R Parr Margaret A Pericak-Vance Joseph Piven Gerard D Schellenberg Stephen W Scherer Astrid M Vicente Thomas H Wassink Ellen M Wijsman Catalina Betancur Joseph D Buxbaum Edwin H Cook Louise Gallagher Michael Gill Joachim Hallmayer Andrew D Paterson James S Sutcliffe Peter Szatmari Veronica J Vieland Hakon Hakonarson Bernie Devlin

Hum Mol Genet 2012 Nov 26;21(21):4781-92. Epub 2012 Jul 26.

Autism Genetics Group, Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471395PMC
November 2012

New susceptibility loci associated with kidney disease in type 1 diabetes.

PLoS Genet 2012 Sep 20;8(9):e1002921. Epub 2012 Sep 20.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.

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September 2012

Does familial clustering of risk factors for long-term diabetic complications leave any place for genes that act independently?

J Cardiovasc Transl Res 2012 Aug 23;5(4):388-98. Epub 2012 Jun 23.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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August 2012

Male sex bias in placental dysfunction.

Am J Med Genet A 2012 Apr 9;158A(4):779-83. Epub 2012 Mar 9.

Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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April 2012

Pathway-based joint effects analysis of rare genetic variants using Genetic Analysis Workshop 17 exon sequence data.

BMC Proc 2011 Nov 29;5 Suppl 9:S45. Epub 2011 Nov 29.

The Centre for Applied Genomics (TCAG) and Program in Genetics and Genome Biology, The Hospital for Sick Children, 101 College Street, Toronto, ON M5G 1L7, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287882PMC
November 2011