Publications





The genomic landscape of tuberous sclerosis complex.
Nat Commun 2017 Jun 15;8:15816. Epub 2017 Jun 15.
Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Avenue NE, Grand Rapids, Michigan 49503, USA.

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
JAMA Oncol 2017 May 4. Epub 2017 May 4.
Center for Clinical Cancer Genetics, Department of Medicine, The University of Chicago, Chicago, Illinois8Committee of Genetics, Genomics, and Systems Biology, The University of Chicago, Chicago, Illinois.



Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.
Cancer Discov 2016 Aug 3;6(8):914-29. Epub 2016 Jun 3.
Dana-Farber Cancer Institute, Boston, Massachusetts. Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts.





Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.
N Engl J Med 2016 Jan 4;374(2):135-45. Epub 2015 Nov 4.




Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
N Engl J Med 2015 Jun 10;372(26):2481-98. Epub 2015 Jun 10.


Genetic modifiers of EGFR dependence in non-small cell lung cancer.
Proc Natl Acad Sci U S A 2014 Dec 15;111(52):18661-6. Epub 2014 Dec 15.
Broad Institute of Harvard and MIT, Cambridge, MA 02142; Departments of Pathology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; and



Landscape of genomic alterations in cervical carcinomas.
Nature 2014 Feb 25;506(7488):371-5. Epub 2013 Dec 25.
1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [4].

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.
Cancer Discov 2013 Dec 27;3(12):1355-63. Epub 2013 Sep 27.
Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain.



Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes.
J Clin Invest 2006 Jan 22;116(1):125-36. Epub 2005 Dec 22.
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.




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