Publications by authors named "Andrew Bottomley"

100Publications

Evaluating the use of the EORTC patient-reported outcome measures for improving inter-rater reliability of CTCAE ratings in a mixed population of cancer patients: study protocol for a randomized controlled trial.

Trials 2020 Oct 13;21(1):849. Epub 2020 Oct 13.

Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Psychiatry I, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1186/s13063-020-04745-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552957PMC
October 2020

Reference values for the EORTC QLQ-C30 in early and metastatic breast cancer.

Eur J Cancer 2020 01 12;125:69-82. Epub 2019 Dec 12.

Department of Quality of Life, European Organization of Research and Treatment for Cancer, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.10.031DOI Listing
January 2020

Current state of quality of life and patient-reported outcomes research.

Eur J Cancer 2019 11 24;121:55-63. Epub 2019 Sep 24.

Department of Gynecology, Medical University Hospital, Graz, Austria.

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http://dx.doi.org/10.1016/j.ejca.2019.08.016DOI Listing
November 2019

A critical evaluation of quality of life in clinical trials of breast cancer patients treated with radiation therapy.

Ann Palliat Med 2017 Dec 24;6(Suppl 2):S223-S232. Epub 2017 Oct 24.

European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://dx.doi.org/10.21037/apm.2017.09.06DOI Listing
December 2017

Reviewing back translation reports of questionnaires: the EORTC conceptual framework and experience.

Expert Rev Pharmacoecon Outcomes Res 2017 Dec 5;17(6):523-530. Epub 2017 Oct 5.

c Center for Clinical Studies , University Hospital Regensburg , Regensburg , Germany.

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http://dx.doi.org/10.1080/14737167.2017.1384316DOI Listing
December 2017

A systematic review of the quality of statistical methods employed for analysing quality of life data in cancer randomised controlled trials.

Eur J Cancer 2017 09 21;83:166-176. Epub 2017 Jul 21.

EORTC Headquarters, Quality of Life Department, Avenue E. Mounier 83, 1200 Bruxelles, Belgium.

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http://dx.doi.org/10.1016/j.ejca.2017.06.025DOI Listing
September 2017

A prospective study to validate the Polish language version of the European Organisation for Research and Treatment of Cancer (EORTC) Colorectal Liver Metastases (QLQ-LMC21) module.

Eur J Oncol Nurs 2017 Aug 31;29:148-154. Epub 2017 May 31.

Health Outcomes Research Unit, Department of Gerontology, Geriatrics, and Social Work, Faculty of Education, Ignatianum Academy, Krakow, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14623889163016
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http://dx.doi.org/10.1016/j.ejon.2017.05.006DOI Listing
August 2017

Making Advances in Quality of Life Studies in Head and Neck Cancer.

Int J Radiat Oncol Biol Phys 2017 03;97(4):659-661

Quality of Life Department, European Organisation for Research and Treatment of Cancer, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2016.11.051DOI Listing
March 2017

A systematic review examining factors influencing health related quality of life among melanoma cancer survivors.

Eur J Cancer 2016 12 11;69:189-198. Epub 2016 Nov 11.

European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ejca.2016.10.008DOI Listing
December 2016

Impact of neurocognitive deficits on patient-proxy agreement regarding health-related quality of life in low-grade glioma patients.

Qual Life Res 2017 04 15;26(4):869-880. Epub 2016 Oct 15.

Department of Medical Psychology - B7D349, VU University Medical Center, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11136-016-1426-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334398PMC
April 2017

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

Eur J Cancer 2016 11 6;68:73-81. Epub 2016 Oct 6.

Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.08.024DOI Listing
November 2016

Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.

Lancet Oncol 2016 Nov 27;17(11):1533-1542. Epub 2016 Sep 27.

Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn, Germany.

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http://dx.doi.org/10.1016/S1470-2045(16)30305-9DOI Listing
November 2016

The Added Value of Analyzing Pooled Health-Related Quality of Life Data: A Review of the EORTC PROBE Initiative.

J Natl Cancer Inst 2016 May 28;108(5). Epub 2015 Dec 28.

European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium (EZ, CC, DEE, FM, IG, AB); European Centre for Disease Prevention and Control, Surveillance and Response Support, Epidemiological Methods Unit, Stockholm, Sweden (CQ); School of Psychology and Sydney Medical School, University of Sydney, New South Wales, Australia (MTK); School of Population and Public Health, University of British Columbia, Vancouver, Canada (CG); The Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada (JR); Leeds Institute of Cancer and Pathology, University of Leeds, St. James's Hospital, Leeds, UK (GV); Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC (BBR); Obstetrics and Gynecology, Medical University Graz, Graz, Austria (EG); Department of Symptom Research, Division of Internal Medicine, The University of Texas Anderson Cancer Center, Houston, TX (CSC); Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Magdeburg, Magdeburg, Germany (HF); VU University Medical Center / Medical Center Haaglanden, Amsterdam/The Hague, the Netherlands (MJBT); Tumor Biology Center, University of Freiburg, Freiburg, Germany (JW); Philosophical Faculty, University of Regensburg, Regensburg, Germany (JSvK); The Academic Medical Center, Amsterdam, the Netherlands (MAGS).

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http://dx.doi.org/10.1093/jnci/djv391DOI Listing
May 2016

Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.

J Clin Oncol 2015 Jul 26;33(19):2166-75. Epub 2015 May 26.

Martin J.B. Taphoorn, Medical Center Haaglanden, the Hague, and VU University Medical Center, Amsterdam, the Netherlands; Roger Henriksson, Cancer Center Stockholm Gotland, Karolinska, Stockholm, and Umeå University, Umeå, Sweden; Andrew Bottomley, European Organisation for Research and Treatment of Cancer, Brussels, Belgium; Timothy Cloughesy, University of California, Los Angeles, Los Angeles; Christina Theodore-Oklota and Arliene Ravelo, Genentech, South San Francisco, CA; Wolfgang Wick, University Hospital of Heidelberg, Heidelberg, Germany; Warren Mason, Princess Margaret Hospital, Toronto, Ontario, Canada; Frank Saran, The Royal Marsden National Health Service Foundation Trust, Surrey, United Kingdom; Ryo Nishikawa, Saitama Medical University, Saitama, Japan; Magalie Hilton, F. Hoffmann-La Roche, Basel, Switzerland; Olivier L. Chinot, Service de Neuro-Oncologie, Aix-Marseille University, Assistance Publique- Hôpitaux de Marseille, Centre Hospitalier Universitaire Timone, Marseille, France.

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http://dx.doi.org/10.1200/JCO.2014.60.3217DOI Listing
July 2015

The impact of bevacizumab on health-related quality of life in patients treated for recurrent glioblastoma: results of the randomised controlled phase 2 BELOB trial.

Eur J Cancer 2015 Jul 17;51(10):1321-30. Epub 2015 Apr 17.

VU University Medical Center, Department of Neurology, PO Box 7057, 1007 MB Amsterdam, The Netherlands; Medical Center Haaglanden, Department of Neurology, PO Box 432, 2501 CK The Hague, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2015.03.025DOI Listing
July 2015

EORTC QLQ-BR23 and FACT-B for the assessment of quality of life in patients with breast cancer: a literature review.

J Comp Eff Res 2015 Mar;4(2):157-66

Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.2217/cer.14.76DOI Listing
March 2015

Development, characteristics and validity of the EORTC QLQ-PR25 and the FACT-P for assessment of quality of life in prostate cancer patients.

J Comp Eff Res 2014 Sep;3(5):523-31

Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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https://www.futuremedicine.com/doi/10.2217/cer.14.41
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http://dx.doi.org/10.2217/cer.14.41DOI Listing
September 2014

Cross-cultural development of a quality-of-life measure for patients with melanoma: phase 3 testing of an EORTC Melanoma Module.

Melanoma Res 2015 Feb;25(1):47-58

aPatricia Ritchie Centre for Cancer Care and Research, The Mater Hospital bThe University of Sydney cThe Psycho-Oncology Co-operative Research Group (PoCoG), University of Sydney dMelanoma Institute Australia eOsman Consulting Pty Ltd fSchool of Psychiatry, University of New South Wales, Sydney, New South Wales gPrincess Alexandra Hospital, Brisbane, Queensland, Australia hMount Vernon Cancer Centre, Northwood iNorfolk and Norwich University Hospital NHS Trust, Norwich, UK jDepartment of Oncology, Karolinska University Hospital kDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden lQuality of Life Department, EORTC Headquarters, Brussels, Belgium mMelanoma and Sarcoma Unit, Veneto Institute of Oncology (IOV-IRCCS), Padova, Italy nFaculty of Medicine, University of Belgrade oUniversity Medical Center, Bezanijska Kosa, Belgrade, Serbia pEindhoven Cancer Registry, Comprehensive Cancer Centre, Eindhoven qCentre of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Tilburg, The Netherlands.

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http://dx.doi.org/10.1097/CMR.0000000000000122DOI Listing
February 2015

Oral-health-related quality of life in patients with cancer: cultural adaptation and the psychometric testing of the Persian version of EORTC QLQ-OH17.

Support Care Cancer 2015 May 15;23(5):1215-24. Epub 2014 Oct 15.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s00520-014-2468-9DOI Listing
May 2015

Joint modeling of longitudinal health-related quality of life data and survival.

Qual Life Res 2015 Apr 14;24(4):795-804. Epub 2014 Oct 14.

Quality of Life Department, European Organisation for Research and Treatment of Cancer, Brussels, Belgium,

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http://dx.doi.org/10.1007/s11136-014-0821-6DOI Listing
April 2015

Comparison of three shortened questionnaires for assessment of quality of life in advanced cancer.

J Palliat Med 2014 Aug 12;17(8):918-23. Epub 2014 Jun 12.

1 Sunnybrook Health Sciences Centre, University of Toronto , Toronto, Ontario, Canada .

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http://www.liebertpub.com/doi/10.1089/jpm.2014.0012
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http://dx.doi.org/10.1089/jpm.2014.0012DOI Listing
August 2014

The reliability and validity of the Iranian version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for patients with Bone Metastases: the EORTC QLQ-BM22.

Expert Rev Pharmacoecon Outcomes Res 2014 Feb 13;14(1):147-56. Epub 2013 Dec 13.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1586/14737167.2014.864559DOI Listing
February 2014

Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.

J Clin Oncol 2013 Nov 7;31(32):4076-84. Epub 2013 Oct 7.

Terri S. Armstrong, University of Texas Health Science Center-School of Nursing; Terri S. Armstrong, Jeffrey S. Wefel, Mark R. Gilbert, Tito R. Mendoza, MD Anderson Cancer Center, Houston, TX; Meihua Wang, Minhee Won, Radiation Therapy Oncology Group Statistical Center; Maria Werner-Wasik, Thomas Jefferson University Hospital, Philadelphia, PA; Andrew Bottomley, Corneel Coens, European Organisation for Research and Treatment of Cancer, Brussels, Belgium; David G. Brachman, Arizona Oncology Services Foundation and Barrow Neurological Institute, Phoenix, AZ; Ali K. Choucair, Mayo Clinic, Jacksonville, FL; Minesh Mehta, University of Maryland, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2013.49.6067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816957PMC
November 2013

Factors influencing health related quality of life in cancer patients with bone metastases.

J Palliat Med 2013 Aug 2;16(8):915-21. Epub 2013 Jul 2.

Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1089/jpm.2012.0623DOI Listing
August 2013

Determinants of quality of life in advanced cancer patients with bone metastases undergoing palliative radiation treatment.

Support Care Cancer 2013 Nov 19;21(11):3021-30. Epub 2013 Jun 19.

Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada, M4N 3M5.

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http://dx.doi.org/10.1007/s00520-013-1876-6DOI Listing
November 2013

Health-related quality of life in patients with brain tumors: limitations and additional outcome measures.

Curr Neurol Neurosci Rep 2013 Jul;13(7):359

Department of Neurology, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1007/s11910-013-0359-yDOI Listing
July 2013

Moving the boundaries of international collaboration on clinical trials and QoL: experiences in oncology and legislation within the European Parliament.

Expert Rev Pharmacoecon Outcomes Res 2013 Feb;13(1):43-5

EORTC, Avenue Mounier, 83/11,1200 Brussels, Belgium.

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http://dx.doi.org/10.1586/erp.12.91DOI Listing
February 2013

Predictive factors for overall quality of life in patients with advanced cancer.

Support Care Cancer 2013 Jun 22;21(6):1709-16. Epub 2013 Jan 22.

Rapid Response Radiotherapy Program, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00520-013-1717-7DOI Listing
June 2013

When a parent has cancer: challenges to patients, their families and health providers.

Expert Rev Pharmacoecon Outcomes Res 2012 Dec;12(6):795-808

Department of Child and Adolescent Psychiatry, University of Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1586/erp.12.62DOI Listing
December 2012

An evaluation of the response category translations of the EORTC QLQ-C30 questionnaire.

Qual Life Res 2013 Aug 2;22(6):1483-90. Epub 2012 Oct 2.

Medical Statistics Team, Division of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1007/s11136-012-0276-6DOI Listing
August 2013

Promoting pan-European cancer research for the benefit of all cancer patients.

Expert Rev Pharmacoecon Outcomes Res 2012 Aug;12(4):443-5

European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.

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http://dx.doi.org/10.1586/erp.12.32DOI Listing
August 2012

An international prospective study establishing minimal clinically important differences in the EORTC QLQ-BM22 and QLQ-C30 in cancer patients with bone metastases.

Support Care Cancer 2012 Dec 6;20(12):3307-13. Epub 2012 May 6.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5.

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http://dx.doi.org/10.1007/s00520-012-1484-xDOI Listing
December 2012

The process of reconciliation: evaluation of guidelines for translating quality-of-life questionnaires.

Expert Rev Pharmacoecon Outcomes Res 2012 Apr;12(2):189-97

University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1586/erp.11.102DOI Listing
April 2012

Trends in translation requests and arising issues regarding cultural adaptation.

Expert Rev Pharmacoecon Outcomes Res 2011 Jun;11(3):307-14

European Organisation for Research and Treatment of Cancer, E. Mounierlaan 83/11, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1586/erp.11.27DOI Listing
June 2011

Interpretation of differential item functioning analyses using external review.

Expert Rev Pharmacoecon Outcomes Res 2010 Jun;10(3):253-8

Section of Population Health, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1586/erp.10.22DOI Listing
June 2010

Review on quality of life issues in patients with primary brain tumors.

Oncologist 2010 27;15(6):618-26. Epub 2010 May 27.

VU University Medical Center, Department of Neurology, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1634/theoncologist.2009-0291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227985PMC
October 2010

Understanding the EORTC QLQ-BM22, the module for patients with bone metastases.

Expert Rev Pharmacoecon Outcomes Res 2009 Oct;9(5):461-5

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto ON M4N 3M5, Canada.

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http://dx.doi.org/10.1586/erp.09.50DOI Listing
October 2009

The practical impact of differential item functioning analyses in a health-related quality of life instrument.

Qual Life Res 2009 Oct 4;18(8):1125-30. Epub 2009 Aug 4.

Section of Population Health, Institute of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1007/s11136-009-9521-zDOI Listing
October 2009

Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastases.

Eur J Cancer 2009 Sep 25;45(14):2510-8. Epub 2009 Jul 25.

Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1016/j.ejca.2009.05.024DOI Listing
September 2009

Health-related quality of life and cancer.

Authors:
Andrew Bottomley

Expert Rev Pharmacoecon Outcomes Res 2009 Feb;9(1):9-11

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http://dx.doi.org/10.1586/14737167.9.1.9DOI Listing
February 2009

Differential item functioning (DIF) in the EORTC QLQ-C30: a comparison of baseline, on-treatment and off-treatment data.

Qual Life Res 2009 Apr 27;18(3):381-8. Epub 2009 Feb 27.

Section of Population Health, Institute of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1007/s11136-009-9453-7DOI Listing
April 2009

Patient-reported outcomes: assessment and current perspectives of the guidelines of the Food and Drug Administration and the reflection paper of the European Medicines Agency.

Eur J Cancer 2009 Feb 14;45(3):347-53. Epub 2008 Nov 14.

EORTC Quality of Life Department, EORTC Headquarters, Avenue E. Mounierlaan, 83/11, Brussels 1200, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490800792
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http://dx.doi.org/10.1016/j.ejca.2008.09.032DOI Listing
February 2009

Evaluating health-related quality of life and symptom burden in brain tumour patients: instruments for use in experimental trials and clinical practice.

Curr Opin Neurol 2008 Dec;21(6):745-53

European Organisation for Research and Treatment of Cancer Headquarters, Quality of Life Department, Brussels, Belgium.

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http://dx.doi.org/10.1097/WCO.0b013e328315ef7dDOI Listing
December 2008