Andrei Goga

Andrei Goga

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Andrei Goga

Andrei Goga

Publications by authors named "Andrei Goga"

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Cancer cells exploit an orphan RNA to drive metastatic progression.

Nat Med 2018 11 5;24(11):1743-1751. Epub 2018 Nov 5.

Department of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, CA, USA.

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http://www.nature.com/articles/s41591-018-0230-4
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http://dx.doi.org/10.1038/s41591-018-0230-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223318PMC
November 2018

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer.

Nat Chem Biol 2018 08 25;14(8):768-777. Epub 2018 Jun 25.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41589-018-0081-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051919PMC
August 2018

New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.

Trends Cancer 2018 04 15;4(4):260-264. Epub 2018 Mar 15.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, 94115, USA; Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California, San Francisco, CA, 94143, USA; Departments of Anatomy and Bioengineering and Therapeutic Sciences and Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA, 94143, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24058033183003
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http://dx.doi.org/10.1016/j.trecan.2018.02.002DOI Listing
April 2018

Cancer recurrence monitoring using hyperpolarized [1-C]pyruvate metabolic imaging in murine breast cancer model.

Magn Reson Imaging 2017 11 15;43:105-109. Epub 2017 Jul 15.

Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA; The UC Berkeley - UCSF Graduate Program in Bioengineering, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0730725X173013
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http://dx.doi.org/10.1016/j.mri.2017.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632580PMC
November 2017

Comprehensive analysis of normal adjacent to tumor transcriptomes.

Nat Commun 2017 10 20;8(1):1077. Epub 2017 Oct 20.

Institute for Computational Health Sciences, University of California, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41467-017-01027-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651823PMC
October 2017

Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques.

Magn Reson Imaging 2017 05 7;38:152-162. Epub 2017 Jan 7.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mri.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360530PMC
May 2017

Reprogramming of Cancer Metabolism by MYC.

Front Cell Dev Biol 2017 11;5:35. Epub 2017 Apr 11.

Department of Cell and Tissue Biology, University of California, San FranciscoSan Francisco, CA, USA.

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http://journal.frontiersin.org/article/10.3389/fcell.2017.00
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http://dx.doi.org/10.3389/fcell.2017.00035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386977PMC
April 2017

Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling.

Proc Natl Acad Sci U S A 2017 03 7;114(12):3121-3126. Epub 2017 Mar 7.

Department of Anatomy and Biomedical Sciences Program, University of California, San Francisco CA 94143-0452;

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http://dx.doi.org/10.1073/pnas.1701464114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373387PMC
March 2017

Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity.

ACS Chem Biol 2016 08 22;11(8):2131-9. Epub 2016 Jul 22.

Departments of Chemistry, Molecular and Cell Biology, and Nutritional Sciences and Toxicology, University of California, Berkeley , Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/acschembio.6b00433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994060PMC
August 2016

GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity.

Cell Chem Biol 2016 05 12;23(5):567-578. Epub 2016 May 12.

Departments of Chemistry and Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24519456163012
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http://dx.doi.org/10.1016/j.chembiol.2016.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876719PMC
May 2016

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer.

Nat Med 2016 04 7;22(4):427-32. Epub 2016 Mar 7.

Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.

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http://dx.doi.org/10.1038/nm.4055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892846PMC
April 2016

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.

Hum Mol Genet 2015 Dec 15;24(25):7421-31. Epub 2015 Oct 15.

Department of Medicine, Institute for Human Genetics, Helen Diller Family Comprehensive Cancer Center and.

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http://dx.doi.org/10.1093/hmg/ddv432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664170PMC
December 2015

Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation.

Curr Biol 2015 Dec 12;25(23):3110-8. Epub 2015 Nov 12.

Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703423PMC
December 2015

Taking on challenging targets: making MYC druggable.

Am Soc Clin Oncol Educ Book 2014 :e497-502

From the Department of Cell & Tissue Biology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA; the Department of Cell & Tissue Biology and Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA; and the Department of Cell & Tissue Biology, Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA.

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http://meetinglibrary.asco.org/content/11400497-144
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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892842PMC
November 2015

Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.

ACS Chem Biol 2015 Jul 7;10(7):1624-30. Epub 2015 May 7.

†Program in Metabolic Biology, Department of Nutritional Sciences and Toxicology, University of California, Berkeley, 127 Morgan Hall, Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/acschembio.5b00053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702252PMC
July 2015

Direct and indirect targeting of MYC to treat acute myeloid leukemia.

Cancer Chemother Pharmacol 2015 Jul 9;76(1):35-46. Epub 2015 May 9.

Department of Laboratory Medicine and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 513 Parnassus Avenue, Room S-561, Box 0451, San Francisco, CA, 94143-0451, USA.

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http://dx.doi.org/10.1007/s00280-015-2766-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485702PMC
July 2015

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.

PLoS Genet 2015 Jul 2;11(7):e1005305. Epub 2015 Jul 2.

Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489858PMC
July 2015

CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation.

Stem Cell Reports 2015 Mar 26;4(3):374-89. Epub 2015 Feb 26.

Department of Cell and Tissue Biology and Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375943PMC
March 2015

Pan-viral-microRNA screening identifies interferon inhibition as a common function of diverse viruses.

Proc Natl Acad Sci U S A 2015 Feb 26;112(6):1856-61. Epub 2015 Jan 26.

Department of Molecular Biosciences, Center for Systems and Synthetic Biology, Center for Infectious Disease, and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712-0162; and

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http://dx.doi.org/10.1073/pnas.1417891112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330743PMC
February 2015

Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness.

ACS Chem Biol 2014 Jun 28;9(6):1340-50. Epub 2014 Apr 28.

Program in Metabolic Biology, Department of Nutritional Sciences and Toxicology, University of California, Berkeley , Berkeley, California 94720, United States.

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http://pubs.acs.org/doi/10.1021/cb5001907
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http://dx.doi.org/10.1021/cb5001907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076040PMC
June 2014

Phase I dose-escalation study of 5-day intermittent oral lapatinib therapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer.

J Clin Oncol 2014 May 7;32(14):1472-9. Epub 2014 Apr 7.

A. Jo Chien, Pamela N. Munster, Michelle E. Melisko, Hope S. Rugo, John W. Park, Andrei Goga, Glenna Auerback, Elham Khanafshar, and Mark M. Moasser, Helen Diller Family Comprehensive Cancer Center; A. Jo Chien, Pamela N. Munster, Michelle E. Melisko, Hope S. Rugo, John W. Park, Andrei Goga, Glenna Auerback, Elham Khanafshar, Karen Ordovas, and Mark M. Moasser, University of California San Francisco, San Francisco, CA; and Kevin M. Koch, GlaxoSmithKline, Research Triangle Park, NC.

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http://jco.ascopubs.org/content/early/2014/04/09/JCO.2013.52
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2013.52.1161
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http://dx.doi.org/10.1200/JCO.2013.52.1161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017711PMC
May 2014

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets.

Cancer Discov 2014 Feb 19;4(2):232-45. Epub 2013 Dec 19.

Departments of 1Medicine, 2Pathology, Microbiology & Immunology, 3Cancer Biology, and 4Biochemistry; 5Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee; Departments of 6Cell & Tissue Biology and 7Medicine, University of California, San Francisco, San Francisco, California; 8Foundation Medicine, Cambridge, Massachusetts; 9Oncosalud; and 10Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Perú

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http://dx.doi.org/10.1158/2159-8290.CD-13-0286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946308PMC
February 2014

Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.

Magn Reson Med 2014 Jan 14;71(1):1-11. Epub 2013 Feb 14.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley, California, USA.

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http://doi.wiley.com/10.1002/mrm.24634
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http://dx.doi.org/10.1002/mrm.24634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659200PMC
January 2014

MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.

Hepatology 2014 Jan 22;59(1):202-15. Epub 2013 Nov 22.

Department of Cell & Tissue Biology, University of California San Francisco, San Francisco, CA; Department of Medicine, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1002/hep.26662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877416PMC
January 2014

Endogenous nuclear RNAi mediates behavioral adaptation to odor.

Cell 2013 Aug;154(5):1010-1022

Departments of Cell & Tissue Biology and Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0512, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274153PMC
August 2013

HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells.

Biochem J 2012 Nov;447(3):417-25

Department of Medicine and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1042/BJ20120724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722874PMC
November 2012

Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation.

Mol Cell 2011 Jun;42(5):624-36

Department of Structural and Chemical Biology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.molcel.2011.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119039PMC
June 2011

Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment.

Sci Transl Med 2011 Mar;3(73):73ra21

George Williams Hooper Foundation, University of California, San Francisco, CA 94143, USA.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30017
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http://dx.doi.org/10.1126/scitranslmed.3001713DOI Listing
March 2011

Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models.

J Magn Reson Imaging 2011 Mar;33(3):692-7

Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94158-2512, USA.

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http://dx.doi.org/10.1002/jmri.22484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566235PMC
March 2011

Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase.

Proc Natl Acad Sci U S A 2010 Aug 19;107(31):13836-41. Epub 2010 Jul 19.

Department of Microbiology and Immunology, G. W. Hooper Research Foundation, University of California, San Francisco, CA 94143, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1008366107
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http://dx.doi.org/10.1073/pnas.1008366107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922232PMC
August 2010

Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.

J Biol Chem 2009 Jul 6;284(27):18515-24. Epub 2009 May 6.

Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.006676
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http://dx.doi.org/10.1074/jbc.M109.006676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709372PMC
July 2009

A 3'UTR pumilio-binding element directs translational activation in olfactory sensory neurons.

Neuron 2009 Jan;61(1):57-70

Cellular and Developmental Biology Program, 1 Shields Drive, University of California, Davis, Davis, CA 95616, USA.

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http://dx.doi.org/10.1016/j.neuron.2008.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274156PMC
January 2009

Anti-oncomir suppression of tumor phenotypes.

Mol Interv 2007 Aug;7(4):199-202, 180

Department of Medicine, University of California, San Francisco, CA 94143, USA.

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http://mr.crossref.org/iPage?doi=10.1124%2Fmi.7.4.6
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http://dx.doi.org/10.1124/mi.7.4.6DOI Listing
August 2007

Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.

Nat Med 2007 Jul 24;13(7):820-7. Epub 2007 Jun 24.

Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, San Francisco, California 94143-0552, USA.

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http://dx.doi.org/10.1038/nm1606DOI Listing
July 2007

Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b.

J Biol Chem 2007 Jan 16;282(2):1479-86. Epub 2006 Nov 16.

Buck Institute for Age Research, Novato, California 94945, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M609383200
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http://dx.doi.org/10.1074/jbc.M609383200DOI Listing
January 2007

RNA interference (RNAi) with RNase III-prepared siRNAs.

Methods Mol Biol 2004 ;252:471-82

G. W. Hooper Foundation, Department of Microbiology and Immunology, University of California, San Francisco, USA.

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http://link.springer.com/10.1385/1-59259-746-7:471
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http://dx.doi.org/10.1385/1-59259-746-7:471DOI Listing
June 2004

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells.

Proc Natl Acad Sci U S A 2002 Jul 2;99(15):9942-7. Epub 2002 Jul 2.

G. W. Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143-0552, USA.

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http://dx.doi.org/10.1073/pnas.152327299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126604PMC
July 2002