Andrei E Medvedev

Andrei E Medvedev

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Andrei E Medvedev

Andrei E Medvedev

Publications by authors named "Andrei E Medvedev"

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35Publications

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Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Infection.

Front Cell Infect Microbiol 2019 22;9:481. Epub 2020 Jan 22.

Department of Immunology, UConn Health School of Medicine, Farmington, CT, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987077PMC
January 2020

Long Noncoding RNAs in Host-Pathogen Interactions.

Trends Immunol 2019 Jun 30;40(6):492-510. Epub 2019 Apr 30.

Department of Immunology, School of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT 06030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906193007
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http://dx.doi.org/10.1016/j.it.2019.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556373PMC
June 2019

IRAK4 activity controls immune responses to intracellular bacteria Listeria monocytogenes and Mycobacterium smegmatis.

J Leukoc Biol 2018 10 11;104(4):811-820. Epub 2018 May 11.

Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut, USA.

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http://dx.doi.org/10.1002/JLB.2A1117-449RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162151PMC
October 2018

The R753Q polymorphism in Toll-like receptor 2 (TLR2) attenuates innate immune responses to mycobacteria and impairs MyD88 adapter recruitment to TLR2.

J Biol Chem 2017 06 25;292(25):10685-10695. Epub 2017 Apr 25.

From the Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030

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http://dx.doi.org/10.1074/jbc.M117.784470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481573PMC
June 2017

Deficiency in IRAK4 activity attenuates manifestations of murine Lupus.

Eur J Immunol 2017 05 31;47(5):880-891. Epub 2017 Mar 31.

Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA.

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http://dx.doi.org/10.1002/eji.201646641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575829PMC
May 2017

Molecular mechanisms of regulation of Toll-like receptor signaling.

J Leukoc Biol 2016 11 24;100(5):927-941. Epub 2016 Jun 24.

Department of Immunology, University of Connecticut Heath Center, Farmington, Connecticut, USA.

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http://dx.doi.org/10.1189/jlb.2MR0316-117RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069093PMC
November 2016

Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity.

J Leukoc Biol 2016 06 10;99(6):839-50. Epub 2016 Mar 10.

Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut, USA

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http://dx.doi.org/10.1189/jlb.2RU1215-575RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608019PMC
June 2016

Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.

J Leukoc Biol 2015 Dec 26;98(6):963-74. Epub 2015 Aug 26.

*Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut, USA; and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1189/jlb.2VMA0515-229RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661042PMC
December 2015

Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.

J Biol Chem 2015 Jul 16;290(31):19218-32. Epub 2015 Jun 16.

From the Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030 and

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http://dx.doi.org/10.1074/jbc.M115.640128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521043PMC
July 2015

E3 ubiquitin ligases Pellinos as regulators of pattern recognition receptor signaling and immune responses.

Immunol Rev 2015 Jul;266(1):109-22

Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://dx.doi.org/10.1111/imr.12298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473797PMC
July 2015

Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.

J Interferon Cytokine Res 2013 Sep 15;33(9):467-84. Epub 2013 May 15.

Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA.

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http://dx.doi.org/10.1089/jir.2012.0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760066PMC
September 2013

IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance.

J Leukoc Biol 2013 Aug 21;94(2):291-300. Epub 2013 May 21.

1.University of Connecticut Health Center, ARB Bldg., Rm. E6032, 263 Farmington Ave., Farmington, CT 06030, USA.

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http://dx.doi.org/10.1189/jlb.0812401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714565PMC
August 2013

R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88.

J Biol Chem 2012 Nov 19;287(45):38327-37. Epub 2012 Sep 19.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M112.375493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488101PMC
November 2012

The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF.

J Immunol 2012 May 2;188(9):4506-15. Epub 2012 Apr 2.

Department of Medical and Research Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4049/jimmunol.1200202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531971PMC
May 2012

Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20.

J Leukoc Biol 2011 Dec 20;90(6):1141-8. Epub 2011 Sep 20.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1189/jlb.0611273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236548PMC
December 2011

Activation of cytokine-producing and antitumor activities of natural killer cells and macrophages by engagement of Toll-like and NOD-like receptors.

Innate Immun 2011 Aug 3;17(4):375-87. Epub 2010 Aug 3.

Department of Microbiology and Immunology, University of Maryland, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1177/1753425910372000DOI Listing
August 2011

Involvement of TLR2 and TLR4 in cell responses to Rickettsia akari.

J Leukoc Biol 2010 Oct 8;88(4):675-85. Epub 2010 Jul 8.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1189/jlb.1009674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974430PMC
October 2010

TLR4/MyD88/PI3K interactions regulate TLR4 signaling.

J Leukoc Biol 2009 Jun 16;85(6):966-77. Epub 2009 Mar 16.

University of Maryland, Baltimore, 660 W. Redwood Street, Room 324, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1189/jlb.1208763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698589PMC
June 2009

Analysis of the functional role of Toll-like receptor-4 tyrosine phosphorylation.

Methods Mol Biol 2009 ;517:145-67

Department of Microbiology and Immunology, University of Maryland, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1007/978-1-59745-541-1_10DOI Listing
May 2009

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity.

J Biol Chem 2008 Sep 11;283(36):24314-25. Epub 2008 Jul 11.

Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M804800200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528983PMC
September 2008

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.

J Biol Chem 2008 Feb 10;283(6):3109-19. Epub 2007 Dec 10.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M707400200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705934PMC
February 2008

Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

J Biol Chem 2007 Jun 28;282(22):16042-53. Epub 2007 Mar 28.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M606781200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675888PMC
June 2007

Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

J Endotoxin Res 2006 ;12(3):133-50

Department of Microbiology and Immunology, University of Maryland, Baltimore (UMB), Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1179/096805106X102255DOI Listing
July 2006

Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview.

J Endotoxin Res 2005 ;11(6):333-9

Department of Microbiology and Immunology, University of Maryland, Baltimore, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1179/096805105X58724DOI Listing
January 2006

Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance.

J Endotoxin Res 2003 ;9(1):60-4

Department of Microbiology and Immunology, University of Maryland, Baltimore 21201, USA.

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http://www.ingentaselect.com/rpsv/cgi-bin/cgi?ini=xref&b
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http://dx.doi.org/10.1179/096805103125001360DOI Listing
August 2003