Andreas von Deimling

Andreas von Deimling

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Andreas von Deimling

Andreas von Deimling

Publications by authors named "Andreas von Deimling"

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Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:
Matthew Clarke Alan Mackay Britta Ismer Jessica C Pickles Ruth G Tatevossian Scott Newman Tejus A Bale Iris Stoler Elisa Izquierdo Sara Temelso Diana M Carvalho Valeria Molinari Anna Burford Louise Howell Alex Virasami Amy R Fairchild Aimee Avery Jane Chalker Mark Kristiansen Kelly Haupfear James D Dalton Wilda Orisme Ji Wen Michael Hubank Kathreena M Kurian Catherine Rowe Mellissa Maybury Stephen Crosier Jeffrey Knipstein Ulrich Schüller Uwe Kordes David E Kram Matija Snuderl Leslie Bridges Andrew J Martin Lawrence J Doey Safa Al-Sarraj Christopher Chandler Bassel Zebian Claire Cairns Rachael Natrajan Jessica K R Boult Simon P Robinson Martin Sill Ira J Dunkel Stephen W Gilheeney Marc K Rosenblum Debbie Hughes Paula Z Proszek Tobey J Macdonald Matthias Preusser Christine Haberler Irene Slavc Roger Packer Ho-Keung Ng Shani Caspi Mara Popović Barbara Faganel Kotnik Matthew D Wood Lissa Baird Monika Ashok Davare David A Solomon Thale Kristin Olsen Petter Brandal Michael Farrell Jane B Cryan Michael Capra Michael Karremann Jens Schittenhelm Martin U Schuhmann Martin Ebinger Winand N M Dinjens Kornelius Kerl Simone Hettmer Torsten Pietsch Felipe Andreiuolo Pablo Hernáiz Driever Andrey Korshunov Lotte Hiddingh Barbara C Worst Dominik Sturm Marc Zuckermann Olaf Witt Tabitha Bloom Clare Mitchell Evelina Miele Giovanna Stefania Colafati Francesca Diomedi-Camassei Simon Bailey Andrew S Moore Timothy E G Hassall Stephen P Lowis Maria Tsoli Mark J Cowley David S Ziegler Matthias A Karajannis Kristian Aquilina Darren R Hargrave Fernando Carceller Lynley V Marshall Andreas von Deimling Christof M Kramm Stefan M Pfister Felix Sahm Suzanne J Baker Angela Mastronuzzi Andrea Carai Maria Vinci David Capper Sergey Popov David W Ellison Thomas S Jacques David T W Jones Chris Jones

Cancer Discov 2020 Jul 1;10(7):942-963. Epub 2020 Apr 1.

Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-19-1030DOI Listing
July 2020

Analysis of a Surgical Series of 21 Cerebral Radiation Necroses.

World Neurosurg 2020 May 10;137:e462-e469. Epub 2020 Feb 10.

Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.wneu.2020.02.005DOI Listing
May 2020

Kaposiform hemangioendothelioma and tufted angioma - (epi)genetic analysis including genome-wide methylation profiling.

Ann Diagn Pathol 2020 Feb 10;44:151434. Epub 2019 Dec 10.

Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands; Princess Màxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.151434DOI Listing
February 2020

FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.

Acta Neuropathol 2020 01 31;139(1):175-192. Epub 2019 Aug 31.

Department of Human Genetics OE 6300, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00401-019-02067-zDOI Listing
January 2020

High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma.

Pathol Res Pract 2020 Jan 11;216(1):152728. Epub 2019 Nov 11.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany; NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Luxembourg; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg; National Center of Pathology (NCP), Laboratoire national de santé (LNS), Dudelange, Luxembourg; Luxembourg Centre of Neuropathology (LCNP), Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2019.152728DOI Listing
January 2020

Microscopic brain invasion in meningiomas previously classified as WHO grade I is not associated with patient outcome.

J Neurooncol 2019 Dec 11;145(3):469-477. Epub 2019 Nov 11.

Department of Neurosurgery, Ludwig-Maximilians-University Munich, Marchioninistr. 15, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s11060-019-03312-xDOI Listing
December 2019

Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas.

Acta Neuropathol Commun 2019 12 5;7(1):201. Epub 2019 Dec 5.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF 460, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s40478-019-0851-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896263PMC
December 2019

Primary CNS Alveolar Rhabdomyosarcoma: Importance of Epigenetic and Transcriptomic Assays for Accurate Diagnosis.

J Neuropathol Exp Neurol 2019 11;78(11):1073-1075

Department of Pathology, New York University School of Medicine, New York, New York.

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http://dx.doi.org/10.1093/jnen/nlz083DOI Listing
November 2019

Incidence, mortality and outcome of meningiomas: A population-based study from Germany.

Cancer Epidemiol 2019 10 17;62:101562. Epub 2019 Jul 17.

Department of Neurosurgery, Saarland University, D-66421 Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2019.07.001DOI Listing
October 2019

Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E.

Cancer Res 2019 Oct 7;79(19):4994-5007. Epub 2019 Aug 7.

Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0054DOI Listing
October 2019

Calcifying fibrous tumor and inflammatory myofibroblastic tumor are epigenetically related: A comparative genome-wide methylation study.

Ann Diagn Pathol 2019 Aug 3;41:102-105. Epub 2019 Jun 3.

Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.05.013DOI Listing
August 2019

Assessment of Melanin Content and its Influence on Susceptibility Contrast in Melanoma Metastases.

Clin Neuroradiol 2019 Aug 8. Epub 2019 Aug 8.

Department of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00062-019-00816-xDOI Listing
August 2019

Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT.

Acta Neuropathol Commun 2019 08 30;7(1):140. Epub 2019 Aug 30.

Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s40478-019-0793-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716845PMC
August 2019

Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation.

Int J Cancer 2019 07 20;145(2):461-473. Epub 2019 Jan 20.

Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.32107DOI Listing
July 2019

cIMPACT-NOW: a practical summary of diagnostic points from Round 1 updates.

Brain Pathol 2019 07 22;29(4):469-472. Epub 2019 May 22.

Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bpa.12732DOI Listing
July 2019

Ectopic intracranial retinoblastoma in a 3.5-month-old infant without eye involvement and without evidence of heritability.

Pediatr Blood Cancer 2019 05 2;66(5):e27599. Epub 2019 Jan 2.

Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

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http://doi.wiley.com/10.1002/pbc.27599
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http://dx.doi.org/10.1002/pbc.27599DOI Listing
May 2019

Impact of post-surgical freezing delay on brain tumor metabolomics.

Metabolomics 2019 05 13;15(5):78. Epub 2019 May 13.

Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11306-019-1541-2DOI Listing
May 2019

Evolutionary Trajectories of IDH Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis.

Cancer Cell 2019 04 21;35(4):692-704.e12. Epub 2019 Mar 21.

Division of Molecular Genetics, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Heidelberg Center for Personalized Oncology, DKFZ-HIPO, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108193010
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http://dx.doi.org/10.1016/j.ccell.2019.02.007DOI Listing
April 2019

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre.

Acta Neuropathol Commun 2019 02 20;7(1):24. Epub 2019 Feb 20.

Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-019-0668-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381711PMC
February 2019

Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma.

Cancers (Basel) 2019 Jan 21;11(1). Epub 2019 Jan 21.

Division of Experimental Neurosurgery, Department of Neurosurgery, University Hospital Heidelberg, INF 400, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/cancers11010122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356480PMC
January 2019

Nonmeasurable Speckled Contrast-Enhancing Lesions Appearing During Course of Disease Are Associated With IDH Mutation in High-Grade Astrocytoma Patients.

Int J Radiat Oncol Biol Phys 2018 12 31;102(5):1472-1480. Epub 2018 Jul 31.

Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2004DOI Listing
December 2018

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.

J Clin Oncol 2018 Oct 17:JCO2017764720. Epub 2018 Oct 17.

Eugene I. Hwang and Roger J. Packer, Children's National Medical Center, Washington, DC; Marcel Kool, Lukas Chavez, Sebastian Brabetz, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; David Capper, Andreas von Deimling, and Stefan M. Pfister, University Hospital Heidelberg; Stefan M. Pfister, National Center for Tumor Diseases, Heidelberg; David Capper, Charité Medical University, Berlin, Germany; Peter C. Burger, Johns Hopkins University, Baltimore, MD; Chris Williams-Hughes, Children's Oncology Group, Littleton, CO; Catherine Billups, Yimei Li, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Linda Heier, Weill Cornell Medical College, New York, NY; Alok Jaju, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Jeff Michalski, Washington University School of Medicine, St. Louis, MO; Sarah Leary and James M. Olson, Seattle Children's Hospital and Research Institute; Sarah Leary and James M. Olson, Fred Hutchinson Cancer Research Center, Seattle, WA; Tianni Zhou, California State University, Long Beach, Long Beach, CA; Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; and Ian F. Pollack, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2017.76.4720DOI Listing
October 2018

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling.

Clin Cancer Res 2018 09 11;24(18):4494-4504. Epub 2018 Jun 11.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0763DOI Listing
September 2018

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

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http://dx.doi.org/10.15252/emmm.201708420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886PMC
September 2018

Diagnostic accuracy of DW MR imaging in the differentiation of chordomas and chondrosarcomas of the skull base: A 3.0-T MRI study of 105 cases.

Eur J Radiol 2018 Aug 29;105:119-124. Epub 2018 May 29.

Department of Radiooncology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Heidelberg Ion Therapy Center (HIT), Im Neuenheimer Feld 450, 69120 Heidelberg, Germany; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejrad.2018.05.026DOI Listing
August 2018