Andreas Villunger

Andreas Villunger

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Andreas Villunger

Publications by authors named "Andreas Villunger"

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TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.

FEBS J 2019 Sep 3;286(18):3566-3581. Epub 2019 Jun 3.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Austria.

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http://dx.doi.org/10.1111/febs.14934DOI Listing
September 2019

Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.

EMBO Rep 2019 Aug 17;20(8):e47026. Epub 2019 Jun 17.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.15252/embr.201847026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680171PMC
August 2019

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim.

Cell Death Differ 2019 Jun 12. Epub 2019 Jun 12.

Institute of Medical Microbiology and Hygiene, Faculty of Medicine, Medical Center - University of Freiburg, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41418-019-0365-yDOI Listing
June 2019

BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.

Clin Cancer Res 2019 Mar 28;25(6):1901-1912. Epub 2018 Nov 28.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1548DOI Listing
March 2019

CHK1 dosage in germinal center B cells controls humoral immunity.

Cell Death Differ 2019 Mar 20. Epub 2019 Mar 20.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, 6020, Austria.

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http://www.nature.com/articles/s41418-019-0318-5
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http://dx.doi.org/10.1038/s41418-019-0318-5DOI Listing
March 2019

Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis.

FEBS J 2018 04 24;285(8):1403-1418. Epub 2018 Mar 24.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Austria.

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http://dx.doi.org/10.1111/febs.14426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947286PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Perturbing mitosis for anti-cancer therapy: is cell death the only answer?

EMBO Rep 2018 03 19;19(3). Epub 2018 Feb 19.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria

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http://dx.doi.org/10.15252/embr.201745440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836099PMC
March 2018

The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance.

J Cell Sci 2017 Nov;130(22):3779-3787

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innrain 80, 6020 Innsbruck, Austria

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http://dx.doi.org/10.1242/jcs.203448DOI Listing
November 2017

The corepressor NCOR1 regulates the survival of single-positive thymocytes.

Sci Rep 2017 Nov 21;7(1):15928. Epub 2017 Nov 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-017-15918-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698297PMC
November 2017

Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.

Nat Commun 2017 11 22;8(1):1697. Epub 2017 Nov 22.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innrain 80, A-6020, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41467-017-01850-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700047PMC
November 2017

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.

Nat Commun 2017 10 18;8(1):1028. Epub 2017 Oct 18.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41467-017-01022-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647323PMC
October 2017

The miR-15 family reinforces the transition from proliferation to differentiation in pre-B cells.

EMBO Rep 2017 09 13;18(9):1604-1617. Epub 2017 Jul 13.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria

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http://dx.doi.org/10.15252/embr.201643735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579393PMC
September 2017

Signalling strength determines proapoptotic functions of STING.

Nat Commun 2017 09 5;8(1):427. Epub 2017 Sep 5.

Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-00573-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585373PMC
September 2017

T-cell autonomous death induced by regeneration of inert glucocorticoid metabolites.

Cell Death Dis 2017 07 20;8(7):e2948. Epub 2017 Jul 20.

Biocenter, Division of Developmental Immunology, Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1038/cddis.2017.344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550885PMC
July 2017

The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection.

Cell Death Differ 2017 03 13;24(3):523-533. Epub 2017 Jan 13.

The Walter & Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC 3052, Australia.

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http://dx.doi.org/10.1038/cdd.2016.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344212PMC
March 2017

There is something about BOK we just don't get yet.

FEBS J 2017 03;284(5):708-710

Division of Developmental Immunology, BIOCENTER, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1111/febs.14031DOI Listing
March 2017

Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis.

Genes Dev 2016 10;30(19):2133-2151

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, A6020 Innsbruck, Austria.

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http://dx.doi.org/10.1101/gad.289298.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088563PMC
October 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.

Proc Natl Acad Sci U S A 2016 May 20;113(18):5065-70. Epub 2016 Apr 20.

Program of Cellular and Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, MA 02115; Immune Disease Institute, Harvard Medical School, Boston, MA 02115; Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany;

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http://dx.doi.org/10.1073/pnas.1604529113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983837PMC
May 2016

MOMP in the absence of BH3-only proteins.

Genes Dev 2016 Apr;30(8):878-80

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, A-6020 Innsbruck, Austria; Tyrolean Cancer Research Institute, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1101/gad.281519.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840294PMC
April 2016

Beclin 1 is dispensable for chromosome congression and proper outer kinetochore assembly.

EMBO Rep 2015 Oct 20;16(10):1233-6. Epub 2015 Aug 20.

Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.

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http://embor.embopress.org/cgi/doi/10.15252/embr.201540731
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http://dx.doi.org/10.15252/embr.201540731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766455PMC
October 2015

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.

Cell Rep 2015 Sep 17;12(12):2072-85. Epub 2015 Sep 17.

Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594157PMC
September 2015

The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death.

Sci Rep 2015 Jun 11;5:11268. Epub 2015 Jun 11.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1038/srep11268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462756PMC
June 2015

Expression of the vault RNA protects cells from undergoing apoptosis.

Nat Commun 2015 May 8;6:7030. Epub 2015 May 8.

1] Division of Genomics and RNomics, Medical University Innsbruck, Innsbruck A-6020, Austria [2] Department of Chemistry and Biochemistry, University of Bern, Bern CH-3012, Switzerland.

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http://dx.doi.org/10.1038/ncomms8030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430821PMC
May 2015

The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest.

Nat Commun 2015 Apr 29;6:6891. Epub 2015 Apr 29.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Innrain 80-82, A-6020 Innsbruck, Austria.

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http://www.nature.com/articles/ncomms7891
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http://dx.doi.org/10.1038/ncomms7891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423218PMC
April 2015

Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.

FEBS J 2015 Mar 23;282(5):834-849. Epub 2015 Jan 23.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Austria.

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http://doi.wiley.com/10.1111/febs.13188
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http://dx.doi.org/10.1111/febs.13188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562365PMC
March 2015

Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis.

J Immunol 2015 Feb 29;194(3):1316-22. Epub 2014 Dec 29.

Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institute and Karolinska University Hospital, S-17176 Stockholm, Sweden

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http://dx.doi.org/10.4049/jimmunol.1400637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298126PMC
February 2015

Embryonic stem cell differentiation requires full length Chd1.

Sci Rep 2015 Jan 26;5:8007. Epub 2015 Jan 26.

Division of Molecular Biology, Biocenter, Medical University of Innsbruck, Austria.

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http://dx.doi.org/10.1038/srep08007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306112PMC
January 2015

BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.

EMBO J 2014 Oct 23;33(19):2171-87. Epub 2014 Jul 23.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

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http://dx.doi.org/10.15252/embj.201387244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282505PMC
October 2014

Stop competing, start talking!

EMBO J 2014 Sep 25;33(17):1849-51. Epub 2014 Jul 25.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://emboj.embopress.org/lookup/doi/10.15252/embj.20148946
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http://dx.doi.org/10.15252/embj.201489466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195780PMC
September 2014

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.

Apoptosis 2013 Aug;18(8):1008-16

Departament de Ciències Fisiològiques II, Institut d'Investigació Biomèdica de Bellvitge IDIBELL-Universitat de Barcelona, Campus de Bellvitge, Pavelló de Govern, 4ª planta, L'Hospitalet de Llobregat, 08907 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1007/s10495-013-0850-6DOI Listing
August 2013

Caspase-2 at a glance.

J Cell Sci 2012 Dec;125(Pt 24):5911-5

Division of Developmental Immunology, BIOCENTER, Medical University Innsbruck, Innsbruck, Austria.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.115105
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http://dx.doi.org/10.1242/jcs.115105DOI Listing
December 2012

PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm.

J Cell Sci 2012 Nov 3;125(Pt 21):5233-40. Epub 2012 Sep 3.

Max Planck Institute of Biochemistry, Department for Molecular Medicine, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1242/jcs.112029DOI Listing
November 2012

PIDDosome-independent tumor suppression by Caspase-2.

Cell Death Differ 2012 Oct 18;19(10):1722-32. Epub 2012 May 18.

Division of Developmental Immunology, BIOCENTER, Medical University Innsbruck, Austria.

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http://dx.doi.org/10.1038/cdd.2012.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438502PMC
October 2012

A1/Bfl-1 in leukocyte development and cell death.

Exp Cell Res 2012 Jul 4;318(11):1291-303. Epub 2012 Feb 4.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.yexcr.2012.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405526PMC
July 2012

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD.

Biochem J 2012 Jun;444(3):591-9

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://biochemj.org/lookup/doi/10.1042/BJ20111588
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http://dx.doi.org/10.1042/BJ20111588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365438PMC
June 2012

Apoptosis: a barrier against cancer no more?

Hepatology 2011 Oct;54(4):1121-4

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http://dx.doi.org/10.1002/hep.24637DOI Listing
October 2011

GSK3 TIPping off p53 to unleash PUMA.

Mol Cell 2011 Jun;42(5):555-6

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.molcel.2011.05.022DOI Listing
June 2011

Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.

Cancer Res 2011 May 11;71(10):3603-15. Epub 2011 Mar 11.

Gene Regulation Laboratory, Cancer Therapeutics Program, The Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3289DOI Listing
May 2011

Shaping the T-cell repertoire: a matter of life and death.

Immunol Cell Biol 2011 Jan 9;89(1):33-9. Epub 2010 Nov 9.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1038/icb.2010.127DOI Listing
January 2011

PUMA-mediated tumor suppression: A tale of two stories.

Cell Cycle 2010 Nov 15;9(21):4269-75. Epub 2010 Nov 15.

Biocenter, Innsbruck Medical University, Austria.

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http://dx.doi.org/10.4161/cc.9.21.13666DOI Listing
November 2010

Apoptosis and necroptosis are induced in rainbow trout cell lines exposed to cadmium.

Aquat Toxicol 2010 Aug 10;99(1):73-85. Epub 2010 Apr 10.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Fritz-Preglstr. 3, Innsbruck, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X100011
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http://dx.doi.org/10.1016/j.aquatox.2010.04.005DOI Listing
August 2010

Only the strong survive.

Immunity 2010 Jun;32(6):729-31

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.immuni.2010.06.010DOI Listing
June 2010

Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad.

Blood 2010 Feb 3;115(5):995-1005. Epub 2009 Dec 3.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1182/blood-2009-03-212670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272372PMC
February 2010

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.

Int Immunol 2009 Jun 19;21(6):715-25. Epub 2009 May 19.

Cytokines and Lymphoid Development Unit, Institut Pasteur, 25 rue du Docteur Roux, Paris, France.

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http://dx.doi.org/10.1093/intimm/dxp043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980998PMC
June 2009

Bcl2 family proteins in carcinogenesis and the treatment of cancer.

Apoptosis 2009 Apr;14(4):584-96

Biocenter Division of Developmental Immunology, Innsbruck Medical University, Innsbruck, Austria.

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http://link.springer.com/10.1007/s10495-008-0300-z
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http://dx.doi.org/10.1007/s10495-008-0300-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272401PMC
April 2009

Caspase-2 activation in the absence of PIDDosome formation.

J Cell Biol 2009 Apr 13;185(2):291-303. Epub 2009 Apr 13.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, A-6020 Innsbruck, Austria.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200811105
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http://dx.doi.org/10.1083/jcb.200811105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700374PMC
April 2009

Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development.

J Exp Med 2008 Mar 25;205(3):641-55. Epub 2008 Feb 25.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1084/jem.20071658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275386PMC
March 2008

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice.

Proc Natl Acad Sci U S A 2007 Dec 11;104(51):20606-11. Epub 2007 Dec 11.

Department of Physiology and Medical Physics and Royal College of Surgeons in Ireland Neuroscience Research Centre, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0707906105
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http://dx.doi.org/10.1073/pnas.0707906105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154478PMC
December 2007

Impact of cellular lifespan on the T cell receptor repertoire.

Eur J Immunol 2007 Jul;37(7):1978-85

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1002/eji.200636632DOI Listing
July 2007

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

J Cell Biol 2007 Feb 5;176(4):415-24. Epub 2007 Feb 5.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1083/jcb.200608070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063977PMC
February 2007

Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction.

J Exp Med 2006 Dec 18;203(13):2939-51. Epub 2006 Dec 18.

Division of Developmental Immunology, Biocenter, Innsbruck Medical University, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1084/jem.20061552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118188PMC
December 2006

Apoptosis in activated T cells: what are the triggers, and what the signal transducers?

Cell Cycle 2006 Nov 12;5(21):2421-4. Epub 2006 Sep 12.

Institute for Medical Microbiology, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.4161/cc.5.21.3397DOI Listing
November 2006

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal.

J Exp Med 2006 Jul 26;203(7):1657-63. Epub 2006 Jun 26.

The Campbell family Institute for Breast Cancer Research, University Health Network, Toronto, Ontario M5G 2C1, Canada.

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http://dx.doi.org/10.1084/jem.20060353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118330PMC
July 2006

BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.

J Neurosci 2006 Jul;26(27):7257-64

Division of Neuropathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0196-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673947PMC
July 2006

The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells.

Proc Natl Acad Sci U S A 2006 Jul 10;103(29):10979-84. Epub 2006 Jul 10.

Institute for Medical Microbiology, Technical University Munich, Trogerstrasse 9, D-81675 Munich, Germany.

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http://dx.doi.org/10.1073/pnas.0603625103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544160PMC
July 2006

BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

Blood 2005 Dec 23;106(13):4131-8. Epub 2005 Aug 23.

Division of Experimental Pathophysiology & Immunology, Biocenter, Innsbruck Medical University, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1182/blood-2005-04-1595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895232PMC
December 2005

Death squads enlisted by the tumour suppressor p53.

Biochem Biophys Res Commun 2005 Jun;331(3):786-98

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500706
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http://dx.doi.org/10.1016/j.bbrc.2005.03.183DOI Listing
June 2005

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

Cancer Cell 2005 Mar;7(3):227-38

Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1016/j.ccr.2005.02.008DOI Listing
March 2005

Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim.

J Immunol 2005 Jan;174(2):671-9

Institute for Medical Microbiology, Immunology and Hygiene, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.174.2.671DOI Listing
January 2005

The Bcl-2 protein family and its role in the development of neoplastic disease.

Exp Gerontol 2004 Aug;39(8):1125-35

Institute of Pathophysiology, University of Innsbruck Medical School, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.exger.2004.04.011DOI Listing
August 2004