Andreas Scorilas

Andreas Scorilas

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Andreas Scorilas

Publications by authors named "Andreas Scorilas"

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Next generation sequencing targeted gene panel in Greek MODY patients increases diagnostic accuracy.

Pediatr Diabetes 2020 02 10;21(1):28-39. Epub 2019 Nov 10.

Division of Endocrinology, Diabetes and Metabolism, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, "Aghia Sophia" Children's Hospital, Athens, Greece.

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http://dx.doi.org/10.1111/pedi.12931DOI Listing
February 2020

Identification of novel alternative transcripts of the human Ribonuclease κ (RNASEK) gene using 3' RACE and high-throughput sequencing approaches.

Genomics 2020 01 11;112(1):943-951. Epub 2019 Jun 11.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1016/j.ygeno.2019.06.010DOI Listing
January 2020

High clusterin (CLU) mRNA expression levels in tumors of colorectal cancer patients predict a poor prognostic outcome.

Clin Biochem 2020 Jan 28;75:62-69. Epub 2019 Oct 28.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens GR-15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2019.10.008DOI Listing
January 2020

Heat shock protein beta 3 (HSPB3) is an unfavorable molecular biomarker in colorectal adenocarcinoma.

Mol Carcinog 2020 01 10;59(1):116-125. Epub 2019 Nov 10.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1002/mc.23133DOI Listing
January 2020

Natural Alkaloids Intervening the Insulin Pathway: New Hopes for Anti-Diabetic Agents?

Curr Med Chem 2019 ;26(32):5982-6015

Department of Pharmacognosy and Natural Product Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou 15771, Athens, Greece.

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http://dx.doi.org/10.2174/0929867325666180430152618DOI Listing
December 2019

ΔNp63 transcript loss in bladder cancer constitutes an independent molecular predictor of TaT1 patients post-treatment relapse and progression.

J Cancer Res Clin Oncol 2019 Dec 8;145(12):3075-3087. Epub 2019 Oct 8.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodostrian University of Athens, Panepistimiopolis, 157 01, Athens, Greece.

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http://dx.doi.org/10.1007/s00432-019-03028-5DOI Listing
December 2019

The miR-200 family as prognostic markers in clear cell renal cell carcinoma.

Urol Oncol 2019 Dec 19;37(12):955-963. Epub 2019 Oct 19.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.08.008DOI Listing
December 2019

Identification of a novel, internal tRNA-derived RNA fragment as a new prognostic and screening biomarker in chronic lymphocytic leukemia, using an innovative quantitative real-time PCR assay.

Leuk Res 2019 Dec 11;87:106234. Epub 2019 Oct 11.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, 15701, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.106234DOI Listing
December 2019

The emergence of drug resistance to targeted cancer therapies: Clinical evidence.

Drug Resist Updat 2019 12 26;47:100646. Epub 2019 Sep 26.

Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2019.100646DOI Listing
December 2019

Identification of novel alternative splice variants of the human L-DOPA decarboxylase (DDC) gene in human cancer cells, using high-throughput sequencing approaches.

Gene 2019 Nov 23;719:144075. Epub 2019 Aug 23.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2019.144075DOI Listing
November 2019

Circulating exosomal miRNAs: clinical significance in human cancers.

Expert Rev Mol Diagn 2019 11 20;19(11):979-995. Epub 2019 Oct 20.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens , Athens , Greece.

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http://dx.doi.org/10.1080/14737159.2019.1673732DOI Listing
November 2019

Identification of a novel tRNA-derived RNA fragment exhibiting high prognostic potential in chronic lymphocytic leukemia.

Hematol Oncol 2019 Oct 14;37(4):498-504. Epub 2019 Jun 14.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hon.2616
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http://dx.doi.org/10.1002/hon.2616DOI Listing
October 2019

Unraveling UCA1 lncRNA prognostic utility in urothelial bladder cancer.

Carcinogenesis 2019 Aug;40(8):965-974

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1093/carcin/bgz045DOI Listing
August 2019

Discovery of novel transcripts of the human tissue kallikrein (KLK1) and kallikrein-related peptidase 2 (KLK2) in human cancer cells, exploiting Next-Generation Sequencing technology.

Genomics 2019 07 31;111(4):642-652. Epub 2018 Mar 31.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2018.03.022DOI Listing
July 2019

Uncovering the clinical impact of kallikrein-related peptidase 5 (KLK5) mRNA expression in the colorectal adenoma-carcinoma sequence.

Clin Chem Lab Med 2019 07;57(8):1251-1260

Department of Cellular Physiology, G. Papanicolaou Research Center of Oncology, "Saint Savvas" Cancer Hospital of Athens, Athens, Greece.

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http://dx.doi.org/10.1515/cclm-2018-1010DOI Listing
July 2019

Novel alternative splice variants of the human protein arginine methyltransferase 1 (PRMT1) gene, discovered using next-generation sequencing.

Gene 2019 May 5;699:135-144. Epub 2019 Mar 5.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2019.02.072DOI Listing
May 2019

Molecular characterization, genomic structure and expression analysis of a gene (CATL1/CPT1C) encoding a third member of the human carnitine acyltransferase family.

Genomics 2019 May 22. Epub 2019 May 22.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2019.05.019DOI Listing
May 2019

Evidence for L-Dopa Decarboxylase Involvement in Cancer Cell Cytotoxicity Induced by Docetaxel and Mitoxantrone.

Curr Pharm Biotechnol 2018 ;19(13):1087-1096

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.2174/1389201019666181112103637DOI Listing
March 2019

Molecular cloning of novel transcripts of the adaptor-related protein complex 2 alpha 1 subunit (AP2A1) gene, using Next-Generation Sequencing.

Gene 2018 Dec 4;678:55-64. Epub 2018 Aug 4.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.08.008DOI Listing
December 2018

BCL2L12: a multiply spliced gene with independent prognostic significance in breast cancer.

Clin Chem Lab Med 2018 12;57(2):276-287

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian, University of Athens, Athens, Greece.

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http://www.degruyter.com/view/j/cclm.ahead-of-print/cclm-201
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http://dx.doi.org/10.1515/cclm-2018-0272DOI Listing
December 2018

BCL2L12 improves risk stratification and prediction of BFM-chemotherapy response in childhood acute lymphoblastic leukemia.

Clin Chem Lab Med 2018 11;56(12):2104-2118

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1515/cclm-2018-0507DOI Listing
November 2018

miRNA and long non-coding RNA: molecular function and clinical value in breast and ovarian cancers.

Expert Rev Mol Diagn 2018 11 29;18(11):963-979. Epub 2018 Oct 29.

a Department of Biochemistry and Molecular Biology, Faculty of Biology , National and Kapodistrian University of Athens , Athens , Greece.

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http://dx.doi.org/10.1080/14737159.2018.1538794DOI Listing
November 2018

Clinical utility of microRNAs in renal cell carcinoma: current evidence and future perspectives.

Expert Rev Mol Diagn 2018 11 26;18(11):981-991. Epub 2018 Oct 26.

a Department of Biochemistry and Molecular Biology , National and Kapodistrian University of Athens , Athens , Greece.

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http://dx.doi.org/10.1080/14737159.2018.1539668DOI Listing
November 2018

Expressional profiling and clinical relevance of RNase κ in prostate cancer: a novel indicator of favorable progression-free survival.

J Cancer Res Clin Oncol 2018 Oct 27;144(10):2049-2057. Epub 2018 Jul 27.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Panepistimiopolis, Athens, Greece.

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http://dx.doi.org/10.1007/s00432-018-2719-0DOI Listing
October 2018

The International Society for Enzymology: a glorious history, a golden legacy.

Clin Chem Lab Med 2018 10;56(11):275-276

Department of Medicine-DIMED, University of Padova, Padova, Italy.

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http://www.degruyter.com/view/j/cclm.2018.56.issue-11/cclm-2
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http://dx.doi.org/10.1515/cclm-2018-0766DOI Listing
October 2018

Discovery and expression analysis of novel transcripts of the human SR-related CTD-associated factor 1 (SCAF1) gene in human cancer cells using Next-Generation Sequencing.

Gene 2018 Sep 19;670:155-165. Epub 2018 May 19.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.05.044DOI Listing
September 2018

Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology.

Biol Chem 2018 09;399(9):1065-1071

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, GR-15701 Athens, Greece.

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http://dx.doi.org/10.1515/hsz-2017-0294DOI Listing
September 2018

A comprehensive clinicopathological evaluation of the differential expression of microRNA-331 in breast tumors and its diagnostic significance.

Clin Biochem 2018 Sep 29;60:24-32. Epub 2018 Jul 29.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Panepistimiopolis, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2018.07.008DOI Listing
September 2018

Expression Analysis of miR-29b in Malignant and Benign Breast Tumors: A Promising Prognostic Biomarker for Invasive Ductal Carcinoma With a Possible Histotype-Related Expression Status.

Clin Breast Cancer 2018 08 21;18(4):305-312.e3. Epub 2017 Nov 21.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2017.11.007DOI Listing
August 2018

Human kallikrein-related peptidase 12 (KLK12) splice variants discriminate benign from cancerous breast tumors.

Clin Biochem 2018 Aug 25;58:78-85. Epub 2018 May 25.

Department of Cellular Physiology, G. Papanicolaou Research Center of Oncology, "Saint Savvas" Cancer Hospital of Athens, Athens GR-11522, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2018.05.017DOI Listing
August 2018

Clinical utility of miR-143/miR-182 levels in prognosis and risk stratification specificity of BFM-treated childhood acute lymphoblastic leukemia.

Ann Hematol 2018 Jul 20;97(7):1169-1182. Epub 2018 Mar 20.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Panepistimiopolis, 15701, Athens, Greece.

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http://dx.doi.org/10.1007/s00277-018-3292-yDOI Listing
July 2018

Kallikrein-related peptidases and associated microRNAs as promising prognostic biomarkers in gastrointestinal malignancies.

Biol Chem 2018 07;399(8):821-836

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, Athens GR-15701, Greece.

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http://dx.doi.org/10.1515/hsz-2017-0342DOI Listing
July 2018

Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer.

Ann Transl Med 2018 Jun;6(12):241

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.21037/atm.2018.06.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046292PMC
June 2018

Alternative Splicing Detection Tool-a novel PERL algorithm for sensitive detection of splicing events, based on next-generation sequencing data analysis.

Ann Transl Med 2018 Jun;6(12):244

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, Athens, Greece.

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http://dx.doi.org/10.21037/atm.2018.06.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046290PMC
June 2018

Kallikrein-related peptidase 6 (KLK6) expression differentiates tumor subtypes and predicts clinical outcome in breast cancer patients.

Clin Exp Med 2018 May 12;18(2):203-213. Epub 2018 Feb 12.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, 15701, Athens, Greece.

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http://dx.doi.org/10.1007/s10238-018-0487-4DOI Listing
May 2018

High microRNA-28-5p expression in colorectal adenocarcinoma predicts short-term relapse of node-negative patients and poor overall survival of patients with non-metastatic disease.

Clin Chem Lab Med 2018 05;56(6):990-1000

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece, Phone: +30 2107274306, Fax: +30 2107274158.

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http://dx.doi.org/10.1515/cclm-2017-0430DOI Listing
May 2018

miR-221/222 cluster expression improves clinical stratification of non-muscle invasive bladder cancer (TaT1) patients' risk for short-term relapse and progression.

Genes Chromosomes Cancer 2018 03 15;57(3):150-161. Epub 2017 Dec 15.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Panepistimiopolis, Athens, 157 01, Greece.

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http://dx.doi.org/10.1002/gcc.22516DOI Listing
March 2018

Multianalyte quantitative competitive PCR on optically encoded microspheres for an eight-gene panel related to prostate cancer.

Anal Bioanal Chem 2018 Jan 31;410(3):971-980. Epub 2017 Aug 31.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15771, Athens, Greece.

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http://link.springer.com/10.1007/s00216-017-0595-0
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http://dx.doi.org/10.1007/s00216-017-0595-0DOI Listing
January 2018

Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing.

Sci Rep 2017 12 11;7(1):17299. Epub 2017 Dec 11.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, 15701, Greece.

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http://www.nature.com/articles/s41598-017-16269-6
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http://dx.doi.org/10.1038/s41598-017-16269-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725587PMC
December 2017

miR-34a overexpression predicts poor prognostic outcome in colorectal adenocarcinoma, independently of clinicopathological factors with established prognostic value.

Clin Biochem 2017 Nov 15;50(16-17):918-924. Epub 2017 Jun 15.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens GR-15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2017.06.004DOI Listing
November 2017

miR-10b is a prognostic marker in clear cell renal cell carcinoma.

J Clin Pathol 2017 Oct 30;70(10):854-859. Epub 2017 Mar 30.

Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science at the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1136/jclinpath-2017-204341DOI Listing
October 2017

miR-125b predicts childhood acute lymphoblastic leukaemia poor response to BFM chemotherapy treatment.

Br J Cancer 2017 Sep 8;117(6):801-812. Epub 2017 Aug 8.

Laboratory of Clinical Biochemistry-Molecular Diagnostics, 2nd Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, 'P &A Kyriakou' Children's Hospital, Levadias 13 Street, Athens 11527, Greece.

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http://dx.doi.org/10.1038/bjc.2017.256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589998PMC
September 2017

miR-15a-5p, A Novel Prognostic Biomarker, Predicting Recurrent Colorectal Adenocarcinoma.

Mol Diagn Ther 2017 08;21(4):453-464

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, 15701, Athens, Greece.

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http://dx.doi.org/10.1007/s40291-017-0270-3DOI Listing
August 2017

Identification and molecular cloning of novel transcripts of the human kallikrein-related peptidase 10 (KLK10) gene using next-generation sequencing.

Biochem Biophys Res Commun 2017 06 15;487(4):776-781. Epub 2017 Apr 15.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X173075
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http://dx.doi.org/10.1016/j.bbrc.2017.04.078DOI Listing
June 2017

The transcriptome of a "sleeping" invader: de novo assembly and annotation of the transcriptome of aestivating Cornu aspersum.

BMC Genomics 2017 06 28;18(1):491. Epub 2017 Jun 28.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1186/s12864-017-3885-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490208PMC
June 2017

Upregulated miR-16 expression is an independent indicator of relapse and poor overall survival of colorectal adenocarcinoma patients.

Clin Chem Lab Med 2017 May;55(5):737-747

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimiopolis, 15701 Athens.

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http://dx.doi.org/10.1515/cclm-2016-0756DOI Listing
May 2017

Metformin and Anti-Cancer Therapeutics: Hopes for a More Enhanced Armamentarium Against Human Neoplasias?

Curr Med Chem 2017 ;24(1):14-56

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

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http://www.eurekaselect.com/openurl/content.php?genre=articl
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http://dx.doi.org/10.2174/0929867323666160907161459DOI Listing
April 2017

Elevated expression of miR-24-3p is a potentially adverse prognostic factor in colorectal adenocarcinoma.

Clin Biochem 2017 Apr 7;50(6):285-292. Epub 2016 Dec 7.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens GR-15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2016.11.034DOI Listing
April 2017

Downregulated KLK13 expression in bladder cancer highlights tumor aggressiveness and unfavorable patients' prognosis.

J Cancer Res Clin Oncol 2017 Mar 17;143(3):521-532. Epub 2016 Nov 17.

First Department of Urology, "Laiko" General Hospital, Medical School, University of Athens, Agiou Thoma 17, 11527, Athens, Greece.

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http://dx.doi.org/10.1007/s00432-016-2301-6DOI Listing
March 2017

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Cancer Lett 2017 03 3;388:96-106. Epub 2016 Dec 3.

Biomedical Applications Unit, Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 116 35 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.11.036DOI Listing
March 2017

mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia.

Leuk Res 2017 02 29;53:65-73. Epub 2016 Nov 29.

Second Department of Internal Medicine and Research Unit, University General Hospital "Attikon", 1 Rimini St., Haidari, 12462 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2016.11.014DOI Listing
February 2017

Prognostic and predictive biomarkers in prostate cancer.

Expert Rev Mol Diagn 2015 7;15(12):1567-76. Epub 2015 Nov 7.

a Department of Biochemistry and Molecular Biology , University of Athens , Athens , Greece.

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http://dx.doi.org/10.1586/14737159.2015.1110022DOI Listing
September 2016

BCL2L12 protein overexpression is associated with favorable outcome in diffuse large B-cell lymphoma patients in the rituximab era.

Leuk Lymphoma 2016 09 14;57(9):2199-203. Epub 2016 Jan 14.

a 2nd Department of Internal Medicine, Propaedeutic , Hematology Unit, School of Medicine, National and Kapodistrian University of Athens, "Attikon" University General Hospital , Haidari , Greece ;

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http://dx.doi.org/10.3109/10428194.2015.1126588DOI Listing
September 2016

High miR-96 levels in colorectal adenocarcinoma predict poor prognosis, particularly in patients without distant metastasis at the time of initial diagnosis.

Tumour Biol 2016 Sep 4;37(9):11815-11824. Epub 2016 Apr 4.

Department of Biochemistry and Molecular Biology, University of Athens, Panepistimiopolis, Athens, 15701, Greece.

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http://dx.doi.org/10.1007/s13277-016-5023-0DOI Listing
September 2016

Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets.

Mol Carcinog 2016 08 27;55(8):1229-42. Epub 2015 Aug 27.

Biomedical Applications Unit, Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1002/mc.22365DOI Listing
August 2016

High BAX/BCL2 mRNA ratio predicts favorable prognosis in laryngeal squamous cell carcinoma, particularly in patients with negative lymph nodes at the time of diagnosis.

Clin Biochem 2016 Aug 26;49(12):890-6. Epub 2016 Apr 26.

Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Athens GR-15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2016.04.010DOI Listing
August 2016

Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies.

Expert Opin Ther Targets 2016 Jul 4;20(7):801-18. Epub 2016 Mar 4.

a Department of Biochemistry and Molecular Biology, Faculty of Biology , University of Athens , Athens , Greece.

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https://www.tandfonline.com/doi/full/10.1517/14728222.2016.1
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http://dx.doi.org/10.1517/14728222.2016.1147560DOI Listing
July 2016

Identification of novel alternative splice variants of the BCL2L12 gene in human cancer cells using next-generation sequencing methodology.

Cancer Lett 2016 Apr 18;373(1):119-129. Epub 2016 Jan 18.

Department of Biochemistry and Molecular Biology, University of Athens, Athens, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835160003
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http://dx.doi.org/10.1016/j.canlet.2016.01.019DOI Listing
April 2016

MicroRNA-194 is a Marker for Good Prognosis in Clear Cell Renal Cell Carcinoma.

Cancer Med 2016 Apr 10;5(4):656-64. Epub 2016 Feb 10.

Department of Laboratory Medicine and the Keenan Research Centre for Biomedical Science at the Li KaShing Knowledge Institute, St. Michael's Hospital, Toronto, M5B 1W8, Canada.

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http://dx.doi.org/10.1002/cam4.631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831284PMC
April 2016

Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells.

Clin Transl Sci 2015 Dec 10;8(6):668-75. Epub 2015 Sep 10.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, Greece.

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http://doi.wiley.com/10.1111/cts.12323
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351132PMC
December 2015

Overexpression of BCL2 and BAX following BFM induction therapy predicts ch-ALL patients' poor response to treatment and short-term relapse.

J Cancer Res Clin Oncol 2015 Nov 16;141(11):2023-36. Epub 2015 May 16.

Laboratory of Clinical Biochemistry - Molecular Diagnostics, Second Department of Pediatrics, University of Athens Medical School, "P&A Kyriakou" Children's Hospital, Levadias 13 Str., 115 27, Athens, Greece.

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http://dx.doi.org/10.1007/s00432-015-1982-6DOI Listing
November 2015

KLKB1 mRNA overexpression: A novel molecular biomarker for the diagnosis of chronic lymphocytic leukemia.

Clin Biochem 2015 Sep 17;48(13-14):849-54. Epub 2015 Apr 17.

Department of Biochemistry and Molecular Biology, University of Athens, Athens GR-15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2015.04.007DOI Listing
September 2015

Quantitative analysis of the mRNA expression levels of BCL2 and BAX genes in human osteoarthritis and normal articular cartilage: An investigation into their differential expression.

Mol Med Rep 2015 Sep 16;12(3):4514-4521. Epub 2015 Jun 16.

First Orthopedic Department, Athens University Medical School, Attikon University Hospital, Haidari, Athens 12462, Greece.

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http://dx.doi.org/10.3892/mmr.2015.3939DOI Listing
September 2015

Alpha-enolase is a potential prognostic marker in clear cell renal cell carcinoma.

Clin Exp Metastasis 2015 Aug 3;32(6):531-41. Epub 2015 Jun 3.

Department of Laboratory Medicine, and the Keenan Research Centre for Biomedical Science at the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada,

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http://link.springer.com/content/pdf/10.1007%2Fs10585-015-97
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http://link.springer.com/10.1007/s10585-015-9725-2
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August 2015

Clinical relevance of the deregulated kallikrein-related peptidase 8 mRNA expression in breast cancer: a novel independent indicator of disease-free survival.

Breast Cancer Res Treat 2015 Jul 24;152(2):323-36. Epub 2015 Jun 24.

Department of Biochemistry and Molecular Biology, University of Athens, Panepistimiopolis, 15701, Athens, Greece.

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http://link.springer.com/10.1007/s10549-015-3470-8
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July 2015

L-DOPA decarboxylase mRNA levels provide high diagnostic accuracy and discrimination between clear cell and non-clear cell subtypes in renal cell carcinoma.

Clin Biochem 2015 Jun 23;48(9):590-5. Epub 2015 Feb 23.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, 15701 Athens, Greece. Electronic address:

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June 2015

Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?

Gastroenterol Res Pract 2015 29;2015:319861. Epub 2015 Apr 29.

Department of Biochemistry and Molecular Biology, University of Athens, 15701 Athens, Greece.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429197PMC
June 2015

Profilin-1 expression is associated with high grade and stage and decreased disease-free survival in renal cell carcinoma.

Hum Pathol 2015 May 26;46(5):673-80. Epub 2014 Nov 26.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8; Department of Laboratory Medicine and the Keenan Research Centre for Biomedical Science at the Li KaShing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1T8. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.11.007DOI Listing
May 2015

Uncovering the clinical utility of miR-143, miR-145 and miR-224 for predicting the survival of bladder cancer patients following treatment.

Carcinogenesis 2015 May 24;36(5):528-37. Epub 2015 Mar 24.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, 15701 Athens, Greece and First Department of Urology, "Laiko" General Hospital, Medical School, University of Athens, Agiou Thoma 17, 11527 Athens, Greece

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May 2015

Gemcitabine impacts differentially on bladder and kidney cancer cells: distinct modulations in the expression patterns of apoptosis-related microRNAs and BCL2 family genes.

Tumour Biol 2015 May 2;36(5):3197-207. Epub 2015 Apr 2.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, 15701, Greece.

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http://dx.doi.org/10.1007/s13277-014-2190-8DOI Listing
May 2015

miR-210 is a prognostic marker in clear cell renal cell carcinoma.

J Mol Diagn 2015 Mar 31;17(2):136-44. Epub 2014 Dec 31.

Department of Laboratory Medicine, St. Michael's Hospital, Toronto, Ontario, Canada; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2014.10.005DOI Listing
March 2015

Low expression of miR-126 is a prognostic marker for metastatic clear cell renal cell carcinoma.

Am J Pathol 2015 Mar 5;185(3):693-703. Epub 2015 Jan 5.

Department of Laboratory Medicine and the Keenan Research Centre for Biomedical Science of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.11.017DOI Listing
March 2015

Cytotoxic activity of sunitinib and everolimus in Caki-1 renal cancer cells is accompanied by modulations in the expression of apoptosis-related microRNA clusters and BCL2 family genes.

Biomed Pharmacother 2015 Mar 9;70:33-40. Epub 2015 Jan 9.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2014.12.043DOI Listing
March 2015

miR-224 overexpression is a strong and independent prognosticator of short-term relapse and poor overall survival in colorectal adenocarcinoma.

Int J Oncol 2015 Feb 24;46(2):849-59. Epub 2014 Nov 24.

Department of Biochemistry and Molecular Biology, University of Athens, Panepistimiopolis, Athens, Greece.

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http://dx.doi.org/10.3892/ijo.2014.2775DOI Listing
February 2015

Human L-DOPA decarboxylase mRNA is a target of miR-145: A prediction to validation workflow.

Gene 2015 Jan 29;554(2):174-80. Epub 2014 Oct 29.

Department of Biochemistry and Molecular Biology, University of Athens, Athens 15701, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2014.10.043DOI Listing
January 2015

BCL2L12: a promising molecular prognostic biomarker in breast cancer.

Clin Biochem 2014 Dec 16;47(18):257-62. Epub 2014 Sep 16.

Department of Biochemistry and Molecular Biology, University of Athens, 15701 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2014.09.008DOI Listing
December 2014

A new tumor suppressor role for the Notch pathway in bladder cancer.

Nat Med 2014 Oct 7;20(10):1199-205. Epub 2014 Sep 7.

Biomedical Research Foundation Academy of Athens, Athens, Greece.

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http://dx.doi.org/10.1038/nm.3678DOI Listing
October 2014