Publications by authors named "Andreas P Freidig"

19Publications

Diagnostic markers based on a computational model of lipoprotein metabolism.

J Clin Bioinforma 2011 Oct 26;1(1):29. Epub 2011 Oct 26.

TNO Quality of Life, Business Unit Biosciences, Zeist and Leiden, the Netherlands.

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http://jclinbioinformatics.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/2043-9113-1-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305892PMC
October 2011

New in vitro dermal absorption database and the prediction of dermal absorption under finite conditions for risk assessment purposes.

Regul Toxicol Pharmacol 2010 Jul-Aug;57(2-3):200-9. Epub 2010 Feb 21.

Department of Food & Chemical Risk Analysis, TNO Quality of Life, Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.yrtph.2010.02.008DOI Listing
September 2010

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes.

Biochim Biophys Acta 2010 Jun 20;1801(6):646-54. Epub 2010 Feb 20.

The Netherlands Organization for Applied Scientific Research (TNO) Quality of Life, Utrechtseweg 48, PO Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.bbalip.2010.02.009DOI Listing
June 2010

Developing computational model-based diagnostics to analyse clinical chemistry data.

Brief Bioinform 2010 Jul 7;11(4):403-16. Epub 2010 Jan 7.

U TNO Quality of Life Research Institute and at Leiden Amsterdam Centre for Drug Research at Leiden University.

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http://dx.doi.org/10.1093/bib/bbp071DOI Listing
July 2010

Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats.

Food Chem Toxicol 2008 Nov 22;46(11):3422-8. Epub 2008 Aug 22.

Division of Toxicology, Wageningen University, P.O. Box 8000, 6700 EA Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.fct.2008.08.015DOI Listing
November 2008

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat.

Toxicol Appl Pharmacol 2008 Sep 27;231(2):248-59. Epub 2008 Apr 27.

Division of Toxicology, Wageningen University, Tuinlaan 5, 6703HE Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.taap.2008.04.011DOI Listing
September 2008

Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids.

J Agric Food Chem 2006 Jul;54(15):5350-8

Business Unit Analytical Research, TNO Quality of Life, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1021/jf060723nDOI Listing
July 2006

Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling.

Toxicol Lett 2006 Aug 3;165(1):79-87. Epub 2006 Mar 3.

TNO Quality of Life, PO Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.toxlet.2006.01.017DOI Listing
August 2006

Neurobehavioural evaluation and kinetics of inhalation of constant or fluctuating toluene concentrations in human volunteers.

Environ Toxicol Pharmacol 2005 Nov 11;20(3):431-42. Epub 2005 Jul 11.

TNO Quality of Life, Business Unit Toxicology and Applied Pharmacology, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S138266890500101
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http://dx.doi.org/10.1016/j.etap.2005.05.003DOI Listing
November 2005

Toxicology of chemical mixtures: a challenging quest along empirical sciences.

Environ Toxicol Pharmacol 2004 Dec;18(3):185-92

Physiological Sciences Department, TNO Nutrition and Food Research, Utrechtseweg 48, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.etap.2004.07.005DOI Listing
December 2004

Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes.

Drug Metab Dispos 2004 Aug;32(8):884-91

Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 2, P.O. Box 80176, 3508 TD Utrecht, The Netherlands.

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http://dx.doi.org/10.1124/dmd.32.8.884DOI Listing
August 2004

The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethylene.

Environ Toxicol Pharmacol 2002 Jul;11(3-4):259-71

Toxicology Division, TNO Nutrition and Food Research Institute, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/s1382-6689(02)00019-4DOI Listing
July 2002