Andreas Muhs

Andreas Muhs

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Andreas Muhs

Andreas Muhs

Publications by authors named "Andreas Muhs"

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33Publications

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Discovery and characterization of novel indole and 7-azaindole derivatives as inhibitors of β-amyloid-42 aggregation for the treatment of Alzheimer's disease.

Bioorg Med Chem Lett 2017 03 4;27(6):1405-1411. Epub 2017 Feb 4.

AC Immune SA, EPFL Innovation Park, Building B, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.02.001DOI Listing
March 2017

Synthesis and structure-activity relationship of 2,6-disubstituted pyridine derivatives as inhibitors of β-amyloid-42 aggregation.

Bioorg Med Chem Lett 2016 07 13;26(14):3330-3335. Epub 2016 May 13.

AC Immune SA, EPFL Innovation Park, Building B, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.05.040DOI Listing
July 2016

Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes. Update 2014.

J Alzheimers Dis 2014 ;42(1):1-68

AC Immune SA, EPFL, Lausanne, Switzerland.

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http://dx.doi.org/10.3233/JAD-140402DOI Listing
May 2015

Human genome-guided identification of memory-modulating drugs.

Proc Natl Acad Sci U S A 2013 Nov 21;110(46):E4369-74. Epub 2013 Oct 21.

Department of Psychology, Division of Molecular Neuroscience, Psychiatric University Clinics, Transfaculty Research Platform, Department Biozentrum, Life Sciences Training Facility, and Department of Psychology, Division of Cognitive Neuroscience, University of Basel, 4055 Basel, Switzerland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1314478110
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http://dx.doi.org/10.1073/pnas.1314478110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831994PMC
November 2013

Dynamic nuclear polarization NMR spectroscopy: revealing multiple conformations in lipid-anchored peptide vaccines.

Angew Chem Int Ed Engl 2013 Oct 23;52(41):10905-8. Epub 2013 Aug 23.

NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht (The Netherlands).

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http://dx.doi.org/10.1002/anie.201303374DOI Listing
October 2013

Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors.

J Alzheimers Dis 2012 ;32(4):793-887

AC Immune SA, EPFL, Lausanne, Switzerland.

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http://dx.doi.org/10.3233/JAD-2012-121186DOI Listing
August 2013

Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes.

J Alzheimers Dis 2013 ;33(3):547-658

AC Immune SA, EPFL, Lausanne, Switzerland.

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/JAD-2012-121537DOI Listing
June 2013

A C-linked disaccharide analogue of Thomsen-Friedenreich epitope induces a strong immune response in mice.

Chemistry 2012 Jul 12;18(28):8578-82. Epub 2012 Jun 12.

Laboratory of Glycochemistry and Asymmetric Synthesis (LGSA), Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1002/chem.201200364DOI Listing
July 2012

Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[18F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography.

Nucl Med Biol 2012 Apr 1;39(3):315-23. Epub 2011 Dec 1.

Karolinska Institutet, Department of Clinical Neuroscience, Psychiatry Section, Karolinska University Hospital, S-17176 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.nucmedbio.2011.09.008DOI Listing
April 2012

Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species.

J Biol Chem 2011 Mar 14;286(10):8585-96. Epub 2010 Dec 14.

Laboratory of Molecular Neurobiology and Neuroproteomics, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.172411
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http://dx.doi.org/10.1074/jbc.M110.172411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048741PMC
March 2011