Andreas M Grabrucker, PhD - Ulm University - Prof.

Andreas M Grabrucker

PhD

Ulm University

Prof.

Ulm | Germany

Main Specialties: Neurology

Additional Specialties: Neuroscience, Nanotechnology

Andreas M Grabrucker, PhD - Ulm University - Prof.

Andreas M Grabrucker

PhD

Introduction

Primary Affiliation: Ulm University - Ulm , Germany

Specialties:

Additional Specialties:

Publications

17Publications

358Reads

-Profile Views

540PubMed Central Citations

Characterization of biometal profiles in neurological disorders.

Metallomics 2014 May;6(5):960-77

Institute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.

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http://xlink.rsc.org/?DOI=C4MT00008K
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http://dx.doi.org/10.1039/c4mt00008kDOI Listing
May 2014
6 Reads
19 Citations
3.585 Impact Factor

Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport.

J Control Release 2014 Mar 11;177:96-107. Epub 2014 Jan 11.

WG Molecular Analysis of Synaptopathies, Neurology Dept., Neurocenter of Ulm University, Ulm, Germany; Institute for Anatomy and Cell Biology, Ulm University, Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2014.01.004DOI Listing
March 2014
19 Reads
10 Citations
7.705 Impact Factor

The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.

Exp Neurol 2014 Mar 29;253:126-37. Epub 2013 Dec 29.

WG Molecular Analysis of Synaptopathies, Neurology Dept., Neurocenter of Ulm University, Albert-Einstein Allee 11, 89081 Ulm, Germany; Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein Allee 11, 89081 Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2013.12.015DOI Listing
March 2014
24 Reads
18 Citations
4.700 Impact Factor

A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders.

Dev Neurobiol 2014 Feb 11;74(2):136-46. Epub 2013 Sep 11.

Neurology Department, WG Molecular Analysis of Synaptopathies, Neurocenter of Ulm University, Ulm, Germany; Institute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1002/dneu.22089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272576PMC
February 2014
17 Reads
22 Citations
3.370 Impact Factor

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders.

Brain 2014 Jan 25;137(Pt 1):137-52. Epub 2013 Nov 25.

1 WG Molecular Analysis of Synaptopathies, Neurology Department, Neurocentre of Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1093/brain/awt303DOI Listing
January 2014
82 Reads
35 Citations
9.200 Impact Factor

Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution.

J Control Release 2014 Jan 5;174:195-201. Epub 2013 Dec 5.

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2013.11.023DOI Listing
January 2014
8 Reads
11 Citations
7.705 Impact Factor

The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons.

Neural Dev 2013 Sep 17;8:18. Epub 2013 Sep 17.

Institute for Anatomy and Cell Biology, Ulm University, D-89081 Ulm, Germany.

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http://dx.doi.org/10.1186/1749-8104-8-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849298PMC
September 2013
15 Reads
4 Citations
3.453 Impact Factor

Environmental factors in autism.

Front Psychiatry 2012 18;3:118. Epub 2013 Jan 18.

WG Molecular Analysis of Synaptopathies, Neurology Department, Neurocenter of Ulm University Ulm, Germany.

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http://dx.doi.org/10.3389/fpsyt.2012.00118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548163PMC
January 2013
10 Reads
38 Citations

Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.

J Neurosci 2012 Oct;32(43):14966-78

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94304, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2215-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752148PMC
October 2012
17 Reads
50 Citations
6.344 Impact Factor

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.

Trends Cell Biol 2011 Oct 15;21(10):594-603. Epub 2011 Aug 15.

Institute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1016/j.tcb.2011.07.003DOI Listing
October 2011
5 Reads
62 Citations
12.010 Impact Factor

Brain-Delivery of Zinc-Ions as Potential Treatment for Neurological Diseases: Mini Review.

Drug Deliv Lett 2011 Sep;1(1):13-23

Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford University, Stanford, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220161PMC
September 2011
15 Reads
14 Citations

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold.

Mol Neurodegener 2011 Sep 22;6:65. Epub 2011 Sep 22.

Institute for Anatomy and Cell Biology, Ulm University, Albert Einstein Allee 11, Ulm, 89081, Germany.

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http://dx.doi.org/10.1186/1750-1326-6-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189132PMC
September 2011
6 Reads
12 Citations
6.563 Impact Factor

Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidences.

PLoS One 2011 Mar 23;6(3):e17851. Epub 2011 Mar 23.

Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford University, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017851PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063171PMC
March 2011
22 Reads
10 Citations
3.234 Impact Factor

Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses.

J Biol Chem 2009 Oct 24;284(42):29146-57. Epub 2009 Aug 24.

Institute for Anatomy and Cell Biology, Ulm University, 89081 Ulm, Germany.

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http://dx.doi.org/10.1074/jbc.M109.020628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781459PMC
October 2009
12 Reads
19 Citations
4.573 Impact Factor

Efficient targeting of proteins to post-synaptic densities of excitatory synapses using a novel pSDTarget vector system.

J Neurosci Methods 2009 Jul 22;181(2):227-34. Epub 2009 May 22.

Institute for Anatomy and Cell Biology, Ulm University, Albert Einstein Allee 11, D-89081 Ulm, Germany.

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http://dx.doi.org/10.1016/j.jneumeth.2009.05.008DOI Listing
July 2009
21 Reads
2 Citations
2.025 Impact Factor

Top co-authors

Tobias M Boeckers
Tobias M Boeckers

Institute for Anatomy and Cell Biology

13
Michael J Schmeisser
Michael J Schmeisser

Institute for Anatomy and Cell Biology

8
Craig C Garner
Craig C Garner

Stanford University

5
Michael Schoen
Michael Schoen

Institute for Anatomy and Cell Biology

4
Flavio Forni
Flavio Forni

University of Modena and Reggio Emilia

3
Michael R Kreutz
Michael R Kreutz

Leibniz Institute for Neurobiology

3
Maria Angela Vandelli
Maria Angela Vandelli

University of Modena and Reggio Emilia

3
Juergen Bockmann
Juergen Bockmann

Institute for Anatomy and Cell Biology

3
Giovanni Tosi
Giovanni Tosi

University of Modena and Reggio Emilia

3
Resham Chhabra
Resham Chhabra

Neurodegeneration

3