Publications by authors named "Andreas Lundqvist"

68Publications

Genetically modified immune cells targeting tumor antigens.

Pharmacol Ther 2020 10 15;214:107603. Epub 2020 Jun 15.

Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2020.107603DOI Listing
October 2020

The Multifaceted Roles of CXCL9 Within the Tumor Microenvironment.

Adv Exp Med Biol 2020 ;1231:45-51

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-3-030-36667-4_5DOI Listing
February 2020

Strategies and Techniques for NK Cell Phenotyping.

Methods Mol Biol 2019 ;2032:105-114

Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-9650-6_6DOI Listing
April 2020

Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.

Sci Rep 2019 08 21;9(1):12150. Epub 2019 Aug 21.

Unit of Computational Medicine, Department of Medicine, Centre for Molecular Medicine, Karolinska Institute, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-019-48635-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704156PMC
August 2019

Strategies to Augment Natural Killer (NK) Cell Activity against Solid Tumors.

Cancers (Basel) 2019 Jul 23;11(7). Epub 2019 Jul 23.

Department of Oncology-Pathology, Karolinska Institutet, S-17164 Stockholm, Sweden.

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http://dx.doi.org/10.3390/cancers11071040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678934PMC
July 2019

Evaluation of Breast Cancer and Melanoma Metastasis in Syngeneic Mouse Models.

Methods Mol Biol 2019 ;1913:197-206

Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://link.springer.com/10.1007/978-1-4939-8979-9_14
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http://dx.doi.org/10.1007/978-1-4939-8979-9_14DOI Listing
June 2019

The Role of CXC Chemokine Receptors 1-4 on Immune Cells in the Tumor Microenvironment.

Front Immunol 2018 25;9:2159. Epub 2018 Sep 25.

Cell Therapy Institute, Nova Southeastern University, Fort Lauderdale, FL, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02159
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http://dx.doi.org/10.3389/fimmu.2018.02159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167945PMC
October 2019

"Markers and function of human NK cells in normal and pathological conditions."

Cytometry B Clin Cytom 2017 03;92(2):98-99

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/cyto.b.21520DOI Listing
March 2017

IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.

Blood 2016 09 27;128(11):1475-89. Epub 2016 Jul 27.

Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden; Cell Therapy Institute, Nova Southeastern University, Fort Lauderdale, FL.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025899PMC
http://dx.doi.org/10.1182/blood-2016-02-698027DOI Listing
September 2016

Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.

Eur J Immunol 2015 Jun 17;45(6):1783-93. Epub 2015 Apr 17.

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/eji.201444885
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http://dx.doi.org/10.1002/eji.201444885DOI Listing
June 2015

CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo.

Cancer Immunol Immunother 2015 Feb 26;64(2):225-35. Epub 2014 Oct 26.

Department of Oncology-Pathology, Cancer Center Karolinska, R8:01, Karolinska Institutet, 171 76, Stockholm, Sweden.

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http://link.springer.com/content/pdf/10.1007%2Fs00262-014-16
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http://link.springer.com/10.1007/s00262-014-1629-5
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http://dx.doi.org/10.1007/s00262-014-1629-5DOI Listing
February 2015

Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system.

Int J Mol Sci 2014 Oct 14;15(10):18557-73. Epub 2014 Oct 14.

Karolinska Institutet, Department of Oncology-Pathology, Stockholm S-17176, Sweden.

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http://dx.doi.org/10.3390/ijms151018557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227232PMC
October 2014

Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity.

Clin Cancer Res 2014 Aug 6;20(15):4096-106. Epub 2014 Jun 6.

Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden; and

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0635DOI Listing
August 2014

Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients.

Immunobiology 2014 Mar 12;219(3):189-97. Epub 2013 Oct 12.

Millennium Institute on Immunology and Immunotherapy, Faculty of Medicine, University of Chile, 8380453 Santiago, Chile. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01712985130017
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http://dx.doi.org/10.1016/j.imbio.2013.10.002DOI Listing
March 2014

HLA-dependent tumour development: a role for tumour associate macrophages?

J Transl Med 2013 Oct 6;11:247. Epub 2013 Oct 6.

Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/1479-5876-11-247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856519PMC
October 2013

A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells.

Cancer Immunol Immunother 2013 Aug 21;62(8):1359-68. Epub 2013 May 21.

Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska Institutet, R8:01, 171 76, Stockholm, Sweden.

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http://link.springer.com/content/pdf/10.1007%2Fs00262-013-14
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http://link.springer.com/10.1007/s00262-013-1439-1
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http://dx.doi.org/10.1007/s00262-013-1439-1DOI Listing
August 2013

Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.

Cancer Res 2013 Jul 30;73(13):3877-87. Epub 2013 Apr 30.

Cancer Center Karolinska, Institution of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4115DOI Listing
July 2013

Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling.

Int J Cancer 2013 Oct 11;133(7):1643-52. Epub 2013 Apr 11.

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/ijc.28163
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http://dx.doi.org/10.1002/ijc.28163DOI Listing
October 2013

Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells.

Oncoimmunology 2012 Oct;1(7):1200-1201

Department of Oncology and Pathology; Immune and Gene Therapy Laboratory; Cancer Center Karolinska; Karolinska Institutet; Stockholm, Sweden.

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http://dx.doi.org/10.4161/onci.20685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494645PMC
October 2012

Activated monocytes augment TRAIL-mediated cytotoxicity by human NK cells through release of IFN-γ.

Eur J Immunol 2013 Jan 26;43(1):249-57. Epub 2012 Oct 26.

Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201242735DOI Listing
January 2013

Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours.

J Transl Med 2012 May 22;10:104. Epub 2012 May 22.

Dept of Oncology-Pathology and KcRN, Karolinska Institutet/Karolinska University Hospital, 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1479-5876-10-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478229PMC
May 2012

HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines.

J Immunol 2012 Mar 1;188(5):2136-45. Epub 2012 Feb 1.

Immune and Gene Therapy Laboratory, Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institute, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.1102237DOI Listing
March 2012

Bortezomib Treatment to Potentiate the Anti-tumor Immunity of Ex-vivo Expanded Adoptively Infused Autologous Natural Killer Cells.

J Cancer 2011 1;2:383-5. Epub 2011 Jul 1.

1. Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133963PMC
http://dx.doi.org/10.7150/jca.2.383DOI Listing
July 2011

Unlicensed natural born killers.

Blood 2011 Jun;117(26):6974-5

Karolinska Institutet, National Institutes Of Health.

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http://dx.doi.org/10.1182/blood-2011-05-350314DOI Listing
June 2011

Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways.

Cytotherapy 2011 Mar 14;13(3):269-78. Epub 2010 Oct 14.

Division of Clinical Immunology and Transfusion Medicine, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.3109/14653249.2010.523077DOI Listing
March 2011

Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells.

J Immunol 2010 Feb 21;184(3):1139-42. Epub 2009 Dec 21.

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.0902856DOI Listing
February 2010

Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.

J Clin Invest 2008 Mar;118(3):1099-109

Hematology Branch and Flow Cytometry Core Facility, National Heart, Lung, and Blood Institute, Surgery Branch, National Cancer Institute, Department of Clinical Pathology, Clinical Center, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1172/JCI34409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248804PMC
March 2008

Reduction of GVHD and enhanced antitumor effects after adoptive infusion of alloreactive Ly49-mismatched NK cells from MHC-matched donors.

Blood 2007 Apr 19;109(8):3603-6. Epub 2006 Dec 19.

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-05-02
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http://dx.doi.org/10.1182/blood-2006-05-024315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852249PMC
April 2007

Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity.

Cancer Res 2006 Jul;66(14):7317-25

Hematology Branch, National Heart, Lung, and Blood Institute, Laboratory of Tumor Immunology and Biology, and Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-1202, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0680DOI Listing
July 2006

Treatment of relapsed blast-phase Philadelphia-chromosome-positive leukaemia after non-myeloablative stem-cell transplantation with donor lymphocytes and imatinib.

Lancet Oncol 2005 Oct;6(10):809-12

Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Hatfield CRC, Room 3-5330, 10 Center Drive MSC 1202, Bethesda, MD 20892-1202, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045057039
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http://dx.doi.org/10.1016/S1470-2045(05)70391-0DOI Listing
October 2005

Allogeneic hematopoietic cell transplantation as immunotherapy for solid tumors: current status and future directions.

J Immunother 2005 Jul-Aug;28(4):281-8

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1652, USA.

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http://dx.doi.org/10.1097/01.cji.0000165354.19171.8fDOI Listing
October 2005

Mature dendritic cells induce tumor-specific type 1 regulatory T cells.

J Immunother 2005 May-Jun;28(3):229-35

Cancer Center Karolinska, Immune and Gene Therapy, Department of Oncology and Pathology, Karolinska Institute, S-17176 Stockholm, Sweden.

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http://dx.doi.org/10.1097/01.cji.0000158854.15664.c2DOI Listing
October 2005

Overexpression and functional characterisation of the human melanocortin 4 receptor in Sf9 cells.

Protein Expr Purif 2004 Oct;37(2):455-61

Department of Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, S-221 00 Lund, Sweden.

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http://dx.doi.org/10.1016/j.pep.2004.06.018DOI Listing
October 2004

Allogeneic tumor-dendritic cell fusion vaccines for generation of broad prostate cancer T-cell responses.

Med Oncol 2004 ;21(2):155-65

Cancer Center Karolinska, Immune and Gene Therapy, Department of Oncology and Pathology, Radiumhemmet, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1385/MO:21:2:155DOI Listing
October 2004

Correlation between HLA-A2 gene frequency, latitude, ovarian and prostate cancer mortality rates.

Med Oncol 2004 ;21(1):49-52

Department of Oncology, Radiumhemmet, Karolinska Hospital, 17176 Stockholm, Sweden.

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http://dx.doi.org/10.1385/MO:21:1:49DOI Listing
July 2004

Effects of pH, salt and time on ligand binding properties of overexpressed melanocortin 4 receptor.

J Biochem Biophys Methods 2004 Mar;58(3):195-205

Department of Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, S-221 00, Lund, Sweden.

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http://dx.doi.org/10.1016/j.jbbm.2003.10.007DOI Listing
March 2004

Gene-modified dendritic cells for immunotherapy against cancer.

Med Oncol 2002 ;19(4):197-211

Cancer Center Karolinska, Immune and Gene Therapy, Department of Oncology and Pathology, Radiumhemmet, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1385/MO:19:4:197DOI Listing
April 2003

Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection.

J Immunother 2002 Nov-Dec;25(6):445-54

Immune and Gene Therapy, Cancer Center Karolinska, R8:01, Karolinska Hospital, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1097/00002371-200211000-00001DOI Listing
April 2003

Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis.

Hum Gene Ther 2002 Sep;13(13):1541-9

Immune and Gene Therapy, Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institute, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1089/10430340260201635DOI Listing
September 2002

Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X(L).

Cancer Immunol Immunother 2002 May 1;51(3):139-44. Epub 2002 Mar 1.

Cancer Center Karolinska, Immune and Gene Therapy Laboratory, Department of Oncology and Pathology, Radiumhemmet, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00262-002-0265-7DOI Listing
May 2002

Immobilized-biomembrane affinity chromatography for binding studies of membrane proteins.

J Chromatogr B Analyt Technol Biomed Life Sci 2002 Feb;768(1):31-40

Department of Biochemistry, Biomedical Center, Uppsala University, Sweden.

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http://dx.doi.org/10.1016/s0378-4347(01)00483-2DOI Listing
February 2002

Heat-shock proteins as activators of the innate immune system.

Trends Immunol 2002 Mar;23(3):130-5

Microbiology and Tumor Biology Center, Karolinska Institutet, S-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1016/s1471-4906(01)02168-8DOI Listing
March 2002