Publications by authors named "Andreas Lieb"

20Publications

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy.

Redox Biol 2019 09 19;26:101278. Epub 2019 Jul 19.

UCL Queen Square Institute of Neurology, University College London, Queen Square, London, WC1N, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692059PMC
September 2019

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.

Nat Commun 2019 07 12;10(1):3094. Epub 2019 Jul 12.

Department of Neuromuscular Disorders, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/s41467-019-10910-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626132PMC
July 2019

Designer receptor technology for the treatment of epilepsy.

EBioMedicine 2019 May 9;43:641-649. Epub 2019 May 9.

Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.04.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558262PMC
May 2019

KCC2 overexpression prevents the paradoxical seizure-promoting action of somatic inhibition.

Nat Commun 2019 03 15;10(1):1225. Epub 2019 Mar 15.

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/s41467-019-08933-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420604PMC
March 2019

Epilepsy Gene Therapy Using an Engineered Potassium Channel.

J Neurosci 2019 04 12;39(16):3159-3169. Epub 2019 Feb 12.

Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.1143-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468110PMC
April 2019

Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.

Dis Model Mech 2018 12 14;11(12). Epub 2018 Dec 14.

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK

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http://dx.doi.org/10.1242/dmm.036194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307909PMC
December 2018

Gating defects of disease-causing de novo mutations in Ca1.3 Ca channels.

Channels (Austin) 2018 ;12(1):388-402

a Department of Pharmacology and Toxicology, Institute of Pharmacy and Center for Molecular Biosciences , University of Innsbruck , Innsbruck , Austria.

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http://dx.doi.org/10.1080/19336950.2018.1546518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287693PMC
August 2019

Biochemical autoregulatory gene therapy for focal epilepsy.

Nat Med 2018 09 9;24(9):1324-1329. Epub 2018 Jul 9.

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41591-018-0103-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152911PMC
September 2018

Mechanisms Responsible for ω-Pore Currents in Ca Calcium Channel Voltage-Sensing Domains.

Biophys J 2017 Oct;113(7):1485-1495

Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627182PMC
October 2017

A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.

J Biol Chem 2015 Aug 22;290(34):21086-100. Epub 2015 Jun 22.

From the Institute of Pharmacy, Department of Pharmacology and Toxicology, and Center for Molecular Biosciences, University of Innsbruck, A-6020 Innsbruck, Austria,

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http://www.jbc.org/content/290/34/21086.full.pdf
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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.645671
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http://dx.doi.org/10.1074/jbc.M115.645671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543666PMC
August 2015

CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.

Biol Psychiatry 2015 May 8;77(9):816-22. Epub 2014 Dec 8.

Department of Pharmacology and Toxicology, Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria.. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401440PMC
May 2015

C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1.3 L-type Ca(2+) channels.

Biophys J 2014 Apr;106(7):1467-75

Pharmacology and Toxicology, Institute of Pharmacy, and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976517PMC
April 2014

Structural determinants of CaV1.3 L-type calcium channel gating.

Channels (Austin) 2012 May-Jun;6(3):197-205. Epub 2012 May 1.

Institute of Pharmacy and Center for Molecular Biosciences, University of Innsbruck, Austria.

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http://dx.doi.org/10.4161/chan.21002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431584PMC
December 2012

Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness.

Nat Neurosci 2011 Jan 5;14(1):77-84. Epub 2010 Dec 5.

Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan.

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http://dx.doi.org/10.1038/nn.2694DOI Listing
January 2011

Imaging nanometre-sized hot spots on smooth au films with high-resolution tip-enhanced luminescence and Raman near-field optical microscopy.

Chemphyschem 2008 Feb;9(2):316-20

Institute of Physical and Theoretical Chemistry, Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1002/cphc.200700723DOI Listing
February 2008

A novel immobilization method for single protein spFRET studies.

Biophys J 2005 Aug 20;89(2):L11-3. Epub 2005 May 20.

Department of Biochemistry and Biophysics, University of Rochester, New York 14642, USA.

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http://dx.doi.org/10.1529/biophysj.105.062794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1366648PMC
August 2005