Andreas Hochhaus

Andreas Hochhaus

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Andreas Hochhaus

Andreas Hochhaus

Publications by authors named "Andreas Hochhaus"

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5-Azacytidine modulates CpG methylation levels of EZH2 and NOTCH1 in myelodysplastic syndromes.

J Cancer Res Clin Oncol 2019 Sep 10. Epub 2019 Sep 10.

Abteilung Hämatologie und Internistische Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-019-03016-9DOI Listing
September 2019

Open-Label Phase II Evaluation of Imatinib in Primary Inoperable or Incompletely Resected and Recurrent Glioblastoma.

Oncology 2019 Sep 12:1-7. Epub 2019 Sep 12.

Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany,

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http://dx.doi.org/10.1159/000502483DOI Listing
September 2019

Inhibition of bone morphogenetic protein signaling reduces viability, growth and migratory potential of non-small cell lung carcinoma cells.

J Cancer Res Clin Oncol 2019 Sep 17. Epub 2019 Sep 17.

Klinik Innere Medizin II, Abteilung Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-019-03026-7DOI Listing
September 2019

Dasatinib.

Recent Results Cancer Res 2018;212:29-68

Abteilung Hämatologie/Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Erlanger Allee 101, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/978-3-319-91439-8_2DOI Listing
May 2019

Imatinib dose reduction in major molecular response of chronic myeloid leukemia: results from the German Chronic Myeloid Leukemia-Study IV.

Haematologica 2019 May 4;104(5):955-962. Epub 2018 Dec 4.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.3324/haematol.2018.206797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518910PMC
May 2019

The risk of infections in multiple myeloma before and after the advent of novel agents: a 12-year survey.

Ann Hematol 2019 Mar 24;98(3):713-722. Epub 2019 Jan 24.

Klinik für Innere Medizin II, Abt. Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1007/s00277-019-03621-1DOI Listing
March 2019

Importance of and Satisfaction with Information about Their Disease in Cancer Patients.

J Cancer Educ 2019 Jan 25. Epub 2019 Jan 25.

Klinik für Innere Medizin II, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s13187-019-1480-7DOI Listing
January 2019

A Mosquito Bite with Devastating Complications in an Immunocompromised Patient.

Case Rep Oncol 2019 Jan-Apr;12(1):22-28. Epub 2019 Jan 4.

Klinik für Innere Medizin II, Hämatologie und internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1159/000495878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381905PMC
January 2019

Information needs and usage of complementary and alternative medicine in members of a German self-help group for gastrointestinal stroma tumours, sarcoma, and renal cancer.

Complement Ther Med 2018 Dec 11;41:105-110. Epub 2018 Sep 11.

Klinik für Innere Medizin II, Universitätsklinikum Jena, Am Klinikum 1, 07747 Jena, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09652299183063
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http://dx.doi.org/10.1016/j.ctim.2018.09.008DOI Listing
December 2018

Human MAIT cells are rapidly activated by Aspergillus spp. in an APC-dependent manner.

Eur J Immunol 2018 10 13;48(10):1698-1706. Epub 2018 Aug 13.

Klinik für Innere Medizin II, Hematology and Oncology, Jena University Hospital, Jena, Germany.

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http://dx.doi.org/10.1002/eji.201747312DOI Listing
October 2018

Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia.

Leukemia 2018 09 13;32(9):2046-2049. Epub 2018 Jun 13.

Sektion für Hämatologie, Onkologie und Stammzelltransplantation, Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1038/s41375-018-0157-2DOI Listing
September 2018

[Chronic Myelogenous Leukemia].

Dtsch Med Wochenschr 2018 09 10;143(18):1304-1310. Epub 2018 Sep 10.

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http://dx.doi.org/10.1055/s-0043-121023DOI Listing
September 2018

Managing myeloproliferative neoplasms evidence based on the ELN treatment recommendations 2018.

Leukemia 2018 05 27;32(5):1055-1056. Epub 2018 Feb 27.

Klinik für Innere Medizin II, Hämatologie und Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1038/s41375-018-0079-zDOI Listing
May 2018

Therapy-free remission in chronic myeloid leukemia: possible mechanism.

Expert Rev Hematol 2018 04 9;11(4):269-272. Epub 2018 Mar 9.

b Abteilung Hämatologie/Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena , Jena , Germany.

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http://dx.doi.org/10.1080/17474086.2018.1442213DOI Listing
April 2018

B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.

Cell 2018 04 15;173(2):470-484.e18. Epub 2018 Mar 15.

Department of Systems Biology, Beckman Research Institute, and City of Hope Comprehensive Cancer Center, Monrovia, CA 91016, USA; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.02.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284818PMC
April 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

The use of complementary and alternative medicine by patients in routine care and the risk of interactions.

J Cancer Res Clin Oncol 2018 Mar 22;144(3):551-557. Epub 2018 Jan 22.

Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-018-2587-7DOI Listing
March 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

Bosutinib Versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia: Results From the Randomized BFORE Trial.

J Clin Oncol 2018 01 1;36(3):231-237. Epub 2017 Nov 1.

Jorge E. Cortes, University of Texas MD Anderson Cancer Center, Houston, TX; Carlo Gambacorti-Passerini, University of Milano-Bicocca, Monza, Italy; Michael W. Deininger, University of Utah, Salt Lake City, UT; Michael J. Mauro, Memorial Sloan Kettering Cancer Center, New York, NY; Charles Chuah, Singapore General Hospital, Duke-National University of Singapore Medical School, Singapore, Singapore; Dong-Wook Kim, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, South Korea; Irina Dyagil, National Research Center for Radiation Medicine, Kiev; Nataliia Glushko, Ivano-Frankivsk Regional Clinical Hospital, Ivano-Frankivsk, Ukraine; Dragana Milojkovic, Imperial College London at Hammersmith Hospital London; Laurence Reilly and Allison Jeynes-Ellis, Avillion, London, United Kingdom; Philipp le Coutre, Charité-Universitätsmedizin Berlin, Berlin; Andreas Hochhaus, Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena; Tim H. Brümmendorf, Universitätsklinikum RWTH Aachen, Aachen, Germany; Valentin Garcia-Gutierrez, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain; Eric Leip, Pfizer, Cambridge, MA; Nathalie Bardy-Bouxin, Pfizer International Operation, Paris, France.

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http://dx.doi.org/10.1200/JCO.2017.74.7162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966023PMC
January 2018

Only SETBP1 hotspot mutations are associated with refractory disease in myeloid malignancies.

J Cancer Res Clin Oncol 2017 Dec 14;143(12):2511-2519. Epub 2017 Sep 14.

Abteilung Hämatologie und Internistische Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-017-2518-zDOI Listing
December 2017

Measurement of piperacillin plasma concentrations in cancer patients with suspected infection.

Infection 2017 Oct 17;45(5):629-636. Epub 2017 May 17.

Klinik für Innere Medizin II, Abteilung Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://link.springer.com/10.1007/s15010-017-1026-z
Publisher Site
http://dx.doi.org/10.1007/s15010-017-1026-zDOI Listing
October 2017

Physical and psychosocial aspects of adolescent and young adults after allogeneic hematopoietic stem-cell transplantation: results from a prospective multicenter trial.

J Cancer Res Clin Oncol 2017 Aug 19;143(8):1613-1619. Epub 2017 Apr 19.

Klinik für Innere Medizin II, Abteilung Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-017-2424-4DOI Listing
August 2017

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.

Clin Cancer Res 2017 May 17;23(9):2289-2300. Epub 2016 Nov 17.

Department of Hematology and Oncology with Sections BMT and Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1930DOI Listing
May 2017

Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity.

Eur J Immunol 2017 05 13;47(5):848-859. Epub 2017 Apr 13.

Klinik für Innere Medizin II, Abteilung für Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://doi.wiley.com/10.1002/eji.201646849
Publisher Site
http://dx.doi.org/10.1002/eji.201646849DOI Listing
May 2017

Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia.

Haematologica 2017 04 29;102(4):e129-e131. Epub 2016 Dec 29.

Klinik für Innere Medizin II, Abteilung für Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Germany

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http://dx.doi.org/10.3324/haematol.2016.157180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395123PMC
April 2017

Safety issues and management of toxicities associated with new treatments for multiple myeloma.

Expert Rev Hematol 2017 Mar 27;10(3):193-205. Epub 2017 Jan 27.

a Klinik für Innere Medizin II, Abt. Hämatologie und Internistische Onkologie , Universitätsklinikum Jena , Jena , Germany.

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http://dx.doi.org/10.1080/17474086.2017.1284584DOI Listing
March 2017

Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia.

N Engl J Med 2017 03;376(10):917-927

From Abteilung Hämatologie-Onkologie, Universitätsklinikum Jena, Jena, Germany (A.H.); the Department of Medicine, University of Chicago, Chicago (R.A.L.); INSERM Centre d'Investigation Clinique 1402, Centre Hospitalier Universitaire de Poitiers, Poitiers, France (F.G.); Fred Hutchinson Cancer Research Center, Seattle (J.P.R.); Centre for Cancer Biology, SA Pathology, University of South Australia and University of Adelaide (S.B.), and the South Australian Health and Medical Research Institute and University of Adelaide (T.P.H.), Adelaide, SA, Australia; University of Bologna, Bologna, Italy (M.B.); the University of Utah Huntsman Cancer Institute, Salt Lake City (M.W.D.); the Hematology Department, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona (F.C.); Novartis, Basel, Switzerland (S.F., C.-E.O., H.D.M.); M.D. Anderson Cancer Center, Houston (H.K.); the University of Newcastle, Newcastle, United Kingdom (S.G.O.); and Knight Cancer Institute, Oregon Health and Science University and Howard Hughes Medical Institute, Portland (B.J.D.).

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http://dx.doi.org/10.1056/NEJMoa1609324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901965PMC
March 2017

Outcome of FLT3-ITD-positive acute myeloid leukemia: impact of allogeneic stem cell transplantation and tyrosine kinase inhibitor treatment.

J Cancer Res Clin Oncol 2017 Feb 24;143(2):337-345. Epub 2016 Oct 24.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Am Klinikum 1, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-016-2290-5DOI Listing
February 2017

Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy.

Haematologica 2017 02 17;102(2):e39-e42. Epub 2016 Nov 17.

Faculty of Medicine Carl Gustav Carus, Institute for Medical Informatics and Biometry, Technische Universität Dresden, Mannheim, Germany

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http://dx.doi.org/10.3324/haematol.2016.154138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286951PMC
February 2017

Reply to K.R. Hoffman.

J Clin Oncol 2017 02 14;35(5):567-568. Epub 2016 Nov 14.

Jorge E. Cortes, MD Anderson Cancer Center, Houston, TX; and Andreas Hochhaus, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1200/JCO.2016.70.2944DOI Listing
February 2017

Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia.

J Clin Oncol 2017 Jan 7;35(2):175-184. Epub 2016 Nov 7.

Sieghart Sopper, Günther Gastl, Matthias Baldauf, Zlatko Trajanoski, and Dominik Wolf, Medical University Innsbruck; Sieghart Sopper and Dominik Wolf, Tyrolean Cancer Research Institute; Matthias Baldauf, Oncotyrol, Innsbruck; Peter Valent, Medical University of Vienna, Vienna, Austria; Satu Mustjoki and Kimmo Porkka, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; Deborah White and Timothy Hughes, South Australian Health and Medical Research Institute and University of Adelaide School of Medicine, Adelaide, South Australia, Australia; Andreas Burchert, Universitätsklinikum Gießen und Marburg and Philipps Universität Marburg, Marburg; Andreas Hochhaus, Thomas Ernst, and Thomas Schenk, Universitätsklinikum Jena, Jena; Dominik Wolf, University Hospital of Bonn, Bonn, Germany; Bjørn T. Gjertsen, University of Bergen, Bergen, Norway; Frank Giles, Northwestern University, Chicago, IL; and Jeroen J.W.M. Janssen and Gert J. Ossenkoppele, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2016.67.0893DOI Listing
January 2017

Comparison of two dose levels of cyclophosphamide for successful stem cell mobilization in myeloma patients.

J Cancer Res Clin Oncol 2016 Dec 17;142(12):2603-2610. Epub 2016 Sep 17.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Am Klinikum 1, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-016-2270-9DOI Listing
December 2016

Functional acute liver failure after treatment with pegylated asparaginase in a patient with acute lymphoblastic leukemia: potential impact of plasmapheresis.

Ann Hematol 2016 Oct 4;95(11):1899-901. Epub 2016 Aug 4.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Jena, Germany.

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http://dx.doi.org/10.1007/s00277-016-2773-0DOI Listing
October 2016

Impact of dose intensity of ponatinib on selected adverse events: Multivariate analyses from a pooled population of clinical trial patients.

Leuk Res 2016 09 22;48:84-91. Epub 2016 Jul 22.

ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, MA, 02139-4234, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2016.07.007DOI Listing
September 2016

Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia.

PLoS One 2016 10;11(3):e0150632. Epub 2016 Mar 10.

Klinik für Innere Medizin II, Abteilung für Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150632PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786091PMC
August 2016

Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy.

Clin Cancer Res 2016 Aug 22;22(16):4030-8. Epub 2016 Mar 22.

Hematology Research Unit Helsinki, University of Helsinki and Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland. Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2791DOI Listing
August 2016

EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia.

J Cancer Res Clin Oncol 2016 Jul 11;142(7):1641-50. Epub 2016 May 11.

Abteilung Hämatologie und Internistische Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Erlanger Allee 101, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-016-2174-8DOI Listing
July 2016

Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients Trial.

J Clin Oncol 2016 07 23;34(20):2333-40. Epub 2016 May 23.

Jorge E. Cortes and Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center, Houston, TX; Neil P. Shah, University of California San Francisco School of Medicine, San Francisco, CA; Brigid Bradley-Garelik and George Manos, Bristol-Myers Squibb, Princeton, NJ; Giuseppe Saglio, University of Turin, Turin; Michele Baccarani, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; Jiří Mayer, University Hospital Brno and Central European Institute of Technology, Masaryk University, Brno, Czech Republic; Concepción Boqué, Institut Català d'Oncologia, Hospital Duran i Reynals, L'Hospitalet, Barcelona, Spain; Charles Chuah, Singapore General Hospital, Duke-National University of Singapore Medical School, Singapore; Luis Casanova, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú;and Andreas Hochhaus, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1200/JCO.2015.64.8899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118045PMC
July 2016

Detection of Enterococcus spp. in bronchoalveolar lavage fluid of patients with high-risk neutropenia: May it be ignored?

J Cancer Res Clin Oncol 2016 May 30;142(5):1133-6. Epub 2015 Nov 30.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Erlanger Allee 101, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00432-015-2084-1DOI Listing
May 2016

Case report: false positive elevated serum-galactomannan levels after autologous hematopoietic stem cell transplantation caused by oral nutritional supplements.

Clin Case Rep 2016 05 12;4(5):505-8. Epub 2016 Apr 12.

Klinik für Innere Medizin II Universitätsklinikum Jena Hämatologie und Internistische Onkologie Jena Germany; Centre for Sepsis Control and Care Universitätsklinikum Jena Jena Germany; Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie Hans-Knöll-Institut Jena Germany.

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http://dx.doi.org/10.1002/ccr3.516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856246PMC
May 2016

Biomarker candidates for the detection of an infectious etiology of febrile neutropenia.

Infection 2016 Apr 15;44(2):175-86. Epub 2015 Aug 15.

Institut für Klinische Chemie und Laboratoriumsdiagnostik, Universitätsklinikum Jena, Erlanger Allee 101, 07747, Jena, Germany.

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http://dx.doi.org/10.1007/s15010-015-0830-6DOI Listing
April 2016

Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients.

Blood 2016 Feb 24;127(6):703-12. Epub 2015 Nov 24.

Department of Genetics and Molecular Pathology, SA Pathology, Centre for Cancer Biology, School of Medicine and School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia; and School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia.

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http://dx.doi.org/10.1182/blood-2015-08-660977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760131PMC
February 2016

Clinical Management of Posterior Reversible Encephalopathy Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation: A Case Series and Review of the Literature.

Acta Haematol 2016 4;135(1):1-10. Epub 2015 Jul 4.

Abteilung Hx00E4;matologie und Internistische Onkologie, Klinik fx00FC;r Innere Medizin II, Universitx00E4;tsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1159/000430489DOI Listing
January 2016

Lower gastrointestinal bleeding in a patient with Crohn's disease and plasma cell leukemia in remission.

Ann Hematol 2015 Dec 21;94(12):2063-5. Epub 2015 Aug 21.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1007/s00277-015-2469-xDOI Listing
December 2015

Efficacy of antifungal prophylaxis with oral suspension posaconazole during induction chemotherapy of acute myeloid leukemia.

J Cancer Res Clin Oncol 2015 Sep 24;141(9):1661-8. Epub 2015 Mar 24.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Erlanger Allee 101, 07747, Jena, Germany.

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http://link.springer.com/content/pdf/10.1007/s00432-015-1962
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September 2015

Causes of resistance and treatment choices of second- and third-line treatment in chronic myelogenous leukemia patients.

Ann Hematol 2015 Apr 27;94 Suppl 2:S133-40. Epub 2015 Mar 27.

Abteilung Hämatologie/Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Erlanger Allee 101, 07740, Jena, Germany,

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http://dx.doi.org/10.1007/s00277-015-2323-1DOI Listing
April 2015

Molecular monitoring of chronic myeloid leukemia: principles and interlaboratory standardization.

Ann Hematol 2015 Apr 27;94 Suppl 2:S219-25. Epub 2015 Mar 27.

Faculty of Medicine, University of Southampton, Southampton, UK,

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April 2015

Response-related predictors of survival in CML.

Ann Hematol 2015 Apr 27;94 Suppl 2:S227-39. Epub 2015 Mar 27.

III. Medizinische Klinik, Medizinische Fakultät Mannheim, Universität Heidelberg, Pettenkoferstrasse 22, 68169, Mannheim, Germany,

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April 2015

Different clones of acute leukemia after successful treatment of Hodgkin's disease.

Ann Hematol 2014 Dec 7;93(12):2077-9. Epub 2014 May 7.

Klinik für Innere Medizin II (Abteilung Hämatologie und Internistische Onkologie), Universitätsklinikum Jena, Erlanger Allee 101, 07740, Jena, Germany.

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December 2014

Equivalence of BCR-ABL transcript levels with complete cytogenetic remission in patients with chronic myeloid leukemia in chronic phase.

J Cancer Res Clin Oncol 2014 Nov 22;140(11):1965-9. Epub 2014 Jun 22.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1007/s00432-014-1746-8DOI Listing
November 2014

Dasatinib.

Recent Results Cancer Res 2014 ;201:27-65

III. Medizinische Klinik, Klinikum am Gesundbrunnen, Am Gesundbrunnen 20-24, 74078, Heilbronn, Germany,

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September 2014