Publications by authors named "Andreas Guenther"

71Publications

Defective BACH1/HO-1 regulatory circuits in cystic fibrosis bronchial epithelial cells.

J Cyst Fibros 2020 Jun 11. Epub 2020 Jun 11.

Department of Internal Medicine, Justus-Liebig University, Giessen, Germany; University of Giessen and Marburg Lung Center (UGMLC), Member of the German Centre for Lung Research (DZL), Giessen, Germany; Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany.

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http://dx.doi.org/10.1016/j.jcf.2020.05.006DOI Listing
June 2020

Recognition of breathprints of lung cancer and chronic obstructive pulmonary disease using the Aeonose electronic nose.

J Breath Res 2020 07 24;14(4):046004. Epub 2020 Jul 24.

Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Klinikstr. 33, 35392 Giessen, Germany. European IPF Registry & Biobank (eurIPFreg), 35392 Giessen, Germany.

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http://dx.doi.org/10.1088/1752-7163/ab8c50DOI Listing
July 2020

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair.

Proc Natl Acad Sci U S A 2019 12 27;116(51):25697-25706. Epub 2019 Nov 27.

Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany;

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http://dx.doi.org/10.1073/pnas.1911071116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926051PMC
December 2019

Clinical characteristics of patients with familial idiopathic pulmonary fibrosis (f-IPF).

BMC Pulm Med 2019 Jul 18;19(1):130. Epub 2019 Jul 18.

Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Universities of Giessen and Marburg Lung Center (UGMLC), European IPF Registry (eurIPFreg), Klinikstrasse 36, 35392, Giessen, Germany.

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http://dx.doi.org/10.1186/s12890-019-0895-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637501PMC
July 2019

International Standard Accident Number: A Master Case Index Linking Accident & Emergency with Medical Data.

Stud Health Technol Inform 2019 ;258:120-124

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Braunschweig, Germany.

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August 2019

Lung CT Densitometry in Idiopathic Pulmonary Fibrosis for the Prediction of Natural Course, Severity, and Mortality.

Chest 2019 05 8;155(5):972-981. Epub 2019 Feb 8.

Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany; Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany; German Center for Lung Research; European IPF Registry and Biobank. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.01.019DOI Listing
May 2019

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis.

Sci Rep 2018 08 28;8(1):12983. Epub 2018 Aug 28.

Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München and University Hospital of the Ludwig Maximilians Universität, Member of the German Center for Lung Research (DZL), Munich, Germany.

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http://www.nature.com/articles/s41598-018-31214-x
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http://dx.doi.org/10.1038/s41598-018-31214-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113210PMC
August 2018

Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis.

Am J Respir Crit Care Med 2018 12;198(12):1527-1538

Comprehensive Pneumology Center, Ludwig Maximilian University, University Hospital Grosshadern, and Helmholtz Center Munich, member of the German Center of Lung Research, Munich, Germany.

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http://dx.doi.org/10.1164/rccm.201708-1580OCDOI Listing
December 2018

Hermansky-Pudlak syndrome type 2 manifests with fibrosing lung disease early in childhood.

Orphanet J Rare Dis 2018 03 27;13(1):42. Epub 2018 Mar 27.

Ludwig-Maximilians University, Dr von Haunersches Kinderspital, German Center for Lung Research (DZL), Lindwurmstr. 4, 80337, Munich, Germany.

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http://dx.doi.org/10.1186/s13023-018-0780-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870397PMC
March 2018

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis.

EMBO Mol Med 2018 02;10(2):276-293

Department of Lung Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Bad Nauheim, Germany

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http://dx.doi.org/10.15252/emmm.201606261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801513PMC
February 2018

Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.

PLoS One 2017 18;12(10):e0186615. Epub 2017 Oct 18.

Department of Medicine, Section of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Science Center, New Orleans, LA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186615PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646855PMC
October 2017

Regulation of macroautophagy in amiodarone-induced pulmonary fibrosis.

J Pathol Clin Res 2015 Oct 3;1(4):252-63. Epub 2015 Jun 3.

Department of Internal MedicineJustus-Liebig-UniversityGiessenGermany; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL)GiessenGermany; Member of the European IPF Network; Lung Clinic Waldhof-ElgershausenGreifensteinGermany.

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http://dx.doi.org/10.1002/cjp2.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939895PMC
October 2015

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.

Am J Physiol Lung Cell Mol Physiol 2016 Mar 30;310(6):L519-31. Epub 2015 Dec 30.

Department of Internal Medicine, Justus-Liebig University, Giessen, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Centre for Lung Research (DZL), Giessen, Germany;

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http://dx.doi.org/10.1152/ajplung.00213.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888554PMC
March 2016

A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation.

J Cyst Fibros 2016 05 30;15(3):325-31. Epub 2015 Oct 30.

Department of Pulmonary Medicine, Philipps-University Marburg, Baldingerstrasse 1, Marburg 35043, Germany; Asklepios Fachkliniken München-Gauting, Gauting, Germany; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2015.10.008DOI Listing
May 2016

Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.

Thorax 2015 Nov 10;70(11):1022-32. Epub 2015 Sep 10.

Department of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Excellence Cluster Cardio-Pulmonary System (ECCPS), Giessen, Germany Agaplesion Lung Clinic Waldhof Elgershausen, Greifenstein, Germany European IPF Network and European IPF Registry.

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http://dx.doi.org/10.1136/thoraxjnl-2014-206411DOI Listing
November 2015

Forkhead Box F1 represses cell growth and inhibits COL1 and ARPC2 expression in lung fibroblasts in vitro.

Am J Physiol Lung Cell Mol Physiol 2014 Dec 26;307(11):L838-47. Epub 2014 Sep 26.

INSERM UMR1152, Labex Inflamex, Paris, France; Université Paris Diderot, PRES Sorbonne Paris Cité, Paris, France; Assistance-Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Service de Physiologie-Explorations Fonctionnelles, Paris, France.

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http://dx.doi.org/10.1152/ajplung.00012.2014DOI Listing
December 2014

Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro.

Am J Physiol Lung Cell Mol Physiol 2014 Nov 19;307(10):L791-9. Epub 2014 Sep 19.

Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL); Pneumology, Asklepios Fachkliniken München-Gauting, Germany; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum, Munich, Germany

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http://dx.doi.org/10.1152/ajplung.00167.2014DOI Listing
November 2014

Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis.

Toxicol Sci 2014 Nov 27;142(1):285-97. Epub 2014 Aug 27.

Department of Internal Medicine, Justus-Liebig-University Giessen, Germany Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany Member of the European IPF Network Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany.

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http://dx.doi.org/10.1093/toxsci/kfu177DOI Listing
November 2014

The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis.

J Pathol 2013 Jan;229(2):242-9

Department of Internal Medicine, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Germany.

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http://doi.wiley.com/10.1002/path.4127
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http://dx.doi.org/10.1002/path.4127DOI Listing
January 2013

Update in diffuse parenchymal lung disease 2010.

Am J Respir Crit Care Med 2011 May;183(10):1316-21

Department of Internal Medicine, Medical Clinic II, Justus-Liebig University Giessen, Giessen, Hesse, Germany.

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http://dx.doi.org/10.1164/rccm.201102-0298UPDOI Listing
May 2011

Shedding of low-density lipoprotein receptor–related protein-1 in acute respiratory distress syndrome.

Am J Respir Crit Care Med 2011 Aug;184(4):438-48

Department of Biochemistry, University of Giessen Lung Center, Giessen, Germany

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http://dx.doi.org/10.1164/rccm.201009-1422OCDOI Listing
August 2011

Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis.

Am J Respir Crit Care Med 2011 Jun 11;183(12):1703-14. Epub 2011 Mar 11.

Department of Biochemistry, Faculty of Medicine, University of Giessen Lung Center, Friedrichstrasse 24, 35392 Giessen, Germany.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201009-1479O
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http://dx.doi.org/10.1164/rccm.201009-1479OCDOI Listing
June 2011

Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis.

Thorax 2011 Aug 21;66(8):651-7. Epub 2011 Mar 21.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Perinatal Institute, MLC7029, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://thorax.bmj.com/cgi/doi/10.1136/thx.2010.151555
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http://dx.doi.org/10.1136/thx.2010.151555DOI Listing
August 2011

The backbone of progress--preclinical studies and innovations with zoledronic acid.

Crit Rev Oncol Hematol 2011 Feb;77 Suppl 1:S3-S12

Novartis Pharma AG, Basel, Switzerland.

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http://dx.doi.org/10.1016/S1040-8428(11)70003-8DOI Listing
February 2011

Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia.

Am J Respir Crit Care Med 2010 Jul 8;182(2):207-19. Epub 2010 Apr 8.

Department of Internal Medicine II, University of Giessen Lung Center (UGLC), Klinikstrasse 36, 35392 Giessen, Germany.

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http://dx.doi.org/10.1164/rccm.200909-1414OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913235PMC
July 2010

Induction of tissue factor by urokinase in lung epithelial cells and in the lungs.

Am J Respir Crit Care Med 2010 Jun 1;181(12):1355-66. Epub 2010 Mar 1.

Department of Specialty Care Services, The Texas Lung Injury Institute, University of Texas Health Center at Tyler, 11937 US Highway 271, Tyler, TX 75708, USA.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200901-0015O
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http://dx.doi.org/10.1164/rccm.200901-0015OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894411PMC
June 2010

Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis.

J Aerosol Med Pulm Drug Deliv 2010 Jun;23(3):161-72

Department of Internal Medicine, Faculty of Medicine, Justus Liebig University, Giessen, Germany.

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http://dx.doi.org/10.1089/jamp.2009.0780DOI Listing
June 2010

The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation.

Int J Cancer 2010 Jan;126(1):239-46

Division of Stem Cell Transplantion and Immunotherapy, 2nd Department of Medicine, University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1002/ijc.24758DOI Listing
January 2010

Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.

Am J Respir Crit Care Med 2009 Sep 4;180(5):424-36. Epub 2009 Jun 4.

Division of Surgery, Saban Research Institute of Children's Hospital Los Angeles, University of Southern California, Keck School of Medicine, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1164/rccm.200811-1794OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742760PMC
September 2009

Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung.

Blood 2009 May 30;113(22):5588-98. Epub 2009 Jan 30.

Department of Biochemistry, Faculty of Medicine, University of Giessen Lung Center, Giessen, Germany.

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http://dx.doi.org/10.1182/blood-2008-08-170837DOI Listing
May 2009

Current view on alveolar coagulation and fibrinolysis in acute inflammatory and chronic interstitial lung diseases.

Thromb Haemost 2008 Mar;99(3):494-501

Department of Biochemistry, Faculty of Medicine, University of Giessen Lung Center, Friedrichstrasse 24, 35392 Giessen, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH07-11-0666
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http://dx.doi.org/10.1160/TH07-11-0666DOI Listing
March 2008

Plasminogen activator inhibitor-1 is an inhibitor of factor VII-activating protease in patients with acute respiratory distress syndrome.

J Biol Chem 2007 Jul 31;282(30):21671-82. Epub 2007 May 31.

Department of Biochemistry, Faculty of Medicine, Justus-Liebig-University Giessen, Giessen, Germany.

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http://dx.doi.org/10.1074/jbc.M610748200DOI Listing
July 2007

Raised protein levels and altered cellular expression of factor VII activating protease (FSAP) in the lungs of patients with acute respiratory distress syndrome (ARDS).

Thorax 2007 Oct 4;62(10):880-8. Epub 2007 May 4.

Department of Biochemistry, Faculty of Medicine, University of Giessen Lung Center, Friedrichstrasse 24, 35392 Giessen, Germany.

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http://dx.doi.org/10.1136/thx.2006.069658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094251PMC
October 2007

Synthetic and natural surfactant differentially modulate inflammation after meconium aspiration.

Intensive Care Med 2003 Dec 3;29(12):2247-2254. Epub 2003 Sep 3.

Department of Pediatrics and Neonatology, Justus Liebig University of Giessen, 35392, Giessen, Germany.

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http://dx.doi.org/10.1007/s00134-003-1984-8DOI Listing
December 2003