Publications by authors named "Andreas Greinacher"

100Publications

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.08.008DOI Listing
September 2020

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Authors:
Ming-Huei Chen Laura M Raffield Abdou Mousas Saori Sakaue Jennifer E Huffman Arden Moscati Bhavi Trivedi Tao Jiang Parsa Akbari Dragana Vuckovic Erik L Bao Xue Zhong Regina Manansala Véronique Laplante Minhui Chen Ken Sin Lo Huijun Qian Caleb A Lareau Mélissa Beaudoin Karen A Hunt Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamynaidu Chitrala Kelly Cho Hélène Choquet Adolfo Correa John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans James S Floyd Linda Broer Niels Grarup Michael H Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Qin Qin Huang Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotis Koskeridis Leslie A Lange Terho Lehtimäki Markus M Lerch Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Hilary C Martin Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Matthias Nauck Kjell Nikus Willem H Ouwehand Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari David J Roberts Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Richard C Trembath Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Alan B Zonderman Peter W F Wilson Yun Li Adam S Butterworth Jean-François Gauchat Charleston W K Chiang Bingshan Li Ruth J F Loos William J Astle Evangelos Evangelou David A van Heel Vijay G Sankaran Yukinori Okada Nicole Soranzo Andrew D Johnson Alexander P Reiner Paul L Auer Guillaume Lettre

Cell 2020 Sep;182(5):1198-1213.e14

Montreal Heart Institute, Montreal, QC H1T 1C8, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480402PMC
September 2020

A novel homozygous variant in 2 sisters with thrombocytopenia and severe bleeding tendency.

Platelets 2020 Jul 7:1-4. Epub 2020 Jul 7.

Department of Hematology, Copenhagen University Hospital , Rigshospitalet, Denmark.

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http://dx.doi.org/10.1080/09537104.2020.1786041DOI Listing
July 2020

Severe Hemorrhage Associated With Oral Anticoagulants.

Dtsch Arztebl Int 2020 05;117(18):312-319

Coagulation Center and Research Center, Cardioangiology Center Bethanien Hospital (CCB), Frankfurt/Main; Institute of Biostatistics und Mathematical Modelling, Goethe University, Frankfurt; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt/Main; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Mainz; Department of Anesthesiology, RWTH Aachen University Hospital, Aachen; Department of Clinical Chemistry, Thrombosis and Hemostasis Unit, University Hospital of Kiel and Lübeck, Kiel; Research Center of the Cardioangiology Center Bethanien Hospital (CCB), Frankfurt/Main; Department of Anesthesiology, Intensive Care and Emergency Medicine and Pain Therapy, Vivantes Klinikum im Friedrichshain, Berlin; Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center, Ruhr University Bochum, Bochum; Department of Immunology and Transfusion medicine, University Medicine Greifswald, Greifswald; Thrombosis Research Unit, Center for Internal Medicine 1, Department of Hematology, University Hospital Dresden, Dresden, Germany, and Department of Haematology and Oncology, Kings College London, England; Medical Department 2, Municipal Hospital Dresden-Friedrichstadt, Dresden; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, and Department of Anesthesiology, University Hospital Würzburg, Würzburg; Department of Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald.

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http://dx.doi.org/10.3238/arztebl.2020.0312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358793PMC
May 2020

Function of Large and Small Platelets Differs, Depending on Extracellular Calcium Availability and Type of Inductor.

Thromb Haemost 2020 Jul 11;120(7):1075-1086. Epub 2020 Jun 11.

Institut für Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1055/s-0040-1712447DOI Listing
July 2020

Limitations of the particle immunofiltration assay test for diagnosis of heparin-induced thrombocytopenia.

Am J Hematol 2020 Jun 8. Epub 2020 Jun 8.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1002/ajh.25901DOI Listing
June 2020

Highly impaired platelet ultrastructure in two families with novel variants.

Platelets 2020 May 18:1-6. Epub 2020 May 18.

Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/09537104.2020.1764921DOI Listing
May 2020

Activated platelets kill Staphylococcus aureus, but not Streptococcus pneumoniae-The role of FcγRIIa and platelet factor 4/heparinantibodies.

J Thromb Haemost 2020 06 24;18(6):1459-1468. Epub 2020 Apr 24.

Institut für Immunologie und Transfusion Medizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/jth.14814DOI Listing
June 2020

Quantifying single-platelet biomechanics: An outsider's guide to biophysical methods and recent advances.

Res Pract Thromb Haemost 2020 Mar 17;4(3):386-401. Epub 2020 Feb 17.

Institute of Immunology and Transfusion Medicine University Medicine Greifswald Greifswald Germany.

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http://dx.doi.org/10.1002/rth2.12313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086474PMC
March 2020

An interdisciplinary approach to diagnose and manage Heparin-induced Thrombocytopenia.

Anaesth Crit Care Pain Med 2020 Apr 4;39(2):197-198. Epub 2020 Mar 4.

Institut für Immunologie und Transfusionsmedizin Universitätsmedizin Greifswald, Ferdinand-Sauerbruch-Straße 17475 Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.accpm.2020.03.002DOI Listing
April 2020

Diagnosis of Inherited Platelet Disorders on a Blood Smear.

J Clin Med 2020 Feb 17;9(2). Epub 2020 Feb 17.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, 17489 Greifswald, Germany.

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http://dx.doi.org/10.3390/jcm9020539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074415PMC
February 2020

Physicochemical Characteristics of Platelet Factor 4 under Various Conditions are Relevant for Heparin-Induced Thrombocytopenia Testing.

J Phys Chem B 2020 02 17;124(8):1438-1443. Epub 2020 Feb 17.

Institute for Immunology and Transfusion Medicine , University Medicine of Greifswald , 17475 Greifswald , Mecklenburg-Vorpommern , Germany.

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http://dx.doi.org/10.1021/acs.jpcb.9b11695DOI Listing
February 2020

Ticagrelor causes false-negative functional tests for heparin-induced thrombocytopenia.

Blood 2020 Mar;135(11):875-878

Institut für Immunologie und Transfusionsmedizin, Abteilung für Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany and.

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http://dx.doi.org/10.1182/blood.2019003582DOI Listing
March 2020

Structure and function of the ubiquitin-proteasome system in platelets.

J Thromb Haemost 2020 04 29;18(4):771-780. Epub 2020 Jan 29.

Friedrich Loeffler Institut für Medizinische Mikrobiologie-Virologie, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/jth.14730DOI Listing
April 2020

Platelet Transfusion in Perioperative Medicine.

Semin Thromb Hemost 2020 Feb 12;46(1):50-61. Epub 2019 Dec 12.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1055/s-0039-1697951DOI Listing
February 2020

Characterization of the interaction between platelet factor 4 and homogeneous synthetic low molecular weight heparins.

J Thromb Haemost 2020 02 20;18(2):390-398. Epub 2019 Oct 20.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/jth.14657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236814PMC
February 2020

The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.

Biochim Biophys Acta Proteins Proteom 2020 01 13;1868(1):140281. Epub 2019 Sep 13.

Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany; ZIK HIKE, Center for Innovation Competence "Humoral Immune Reactions in Cardiovascular Diseases", University of Greifswald, 17489 Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2019.140281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905150PMC
January 2020

Reactivity of platelet-activating and nonplatelet-activating anti-PF4/heparin antibodies in enzyme immunosorbent assays under different conditions.

J Thromb Haemost 2019 07 17;17(7):1113-1119. Epub 2019 May 17.

Institute for Immunology and Transfusion Medicine, University Medicine of Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/jth.14455DOI Listing
July 2019

Outcome of an enhanced diagnostic pipeline for patients suspected of inherited thrombocytopenia.

Br J Haematol 2019 07 25;186(2):373-376. Epub 2019 Mar 25.

Centre for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/bjh.15886DOI Listing
July 2019

Mean platelet volume is more important than age for defining reference intervals of platelet counts.

PLoS One 2019 14;14(3):e0213658. Epub 2019 Mar 14.

Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213658PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417788PMC
December 2019

Simplifying the diagnosis of inherited platelet disorders? The new tools do not make it any easier.

Blood 2019 06 11;133(23):2478-2483. Epub 2019 Mar 11.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1182/blood-2019-01-852350DOI Listing
June 2019

Challenging the concept of immunothrombosis.

Blood 2019 02;133(6):508-509

Universitätsmedizin Greifswald.

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http://dx.doi.org/10.1182/blood-2018-11-886267DOI Listing
February 2019

Role of Platelet Size Revisited-Function and Protein Composition of Large and Small Platelets.

Thromb Haemost 2019 Mar 6;119(3):407-420. Epub 2019 Feb 6.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1055/s-0039-1677875DOI Listing
March 2019

Well-being and return rate of first-time whole blood donors.

Vox Sang 2019 Feb 29;114(2):154-161. Epub 2019 Jan 29.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/vox.12752DOI Listing
February 2019

An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia.

J Thromb Haemost 2019 03 20;17(3):525-531. Epub 2019 Feb 20.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/jth.14383DOI Listing
March 2019

Diagnosis of hereditary platelet disorders in the era of next-generation sequencing: "primum non nocere".

J Thromb Haemost 2019 03 3;17(3):551-554. Epub 2019 Feb 3.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://doi.wiley.com/10.1111/jth.14377
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http://dx.doi.org/10.1111/jth.14377DOI Listing
March 2019

Distinct Binding Characteristics of Pathogenic Anti-Platelet Factor-4/Polyanion Antibodies to Antigens Coated on Different Substrates: A Perspective on Clinical Application.

ACS Nano 2018 12 12;12(12):12030-12041. Epub 2018 Dec 12.

Institute for Immunology and Transfusion Medicine , University Medicine Greifswald , 17475 Greifswald , Germany.

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http://pubs.acs.org/doi/10.1021/acsnano.8b04487
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http://dx.doi.org/10.1021/acsnano.8b04487DOI Listing
December 2018

The role of social media for blood donor motivation and recruitment.

Transfusion 2018 10 10;58(10):2257-2259. Epub 2018 Sep 10.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/trf.14823DOI Listing
October 2018

Cold storage of platelets in additive solution: the impact of residual plasma in apheresis platelet concentrates.

Haematologica 2019 01 16;104(1):207-214. Epub 2018 Aug 16.

Centre for Clinical Transfusion Medicine, Medical Faculty of Tübingen, University of Tübingen

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http://dx.doi.org/10.3324/haematol.2018.195057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312032PMC
January 2019

Uptake Pathways of Protein-Coated Magnetic Nanoparticles in Platelets.

ACS Appl Mater Interfaces 2018 Aug 20;10(34):28314-28321. Epub 2018 Aug 20.

Institute for Immunology and Transfusion Medicine , University Medicine Greifswald , 17475 Greifswald , Germany.

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http://pubs.acs.org/doi/10.1021/acsami.8b07588
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http://dx.doi.org/10.1021/acsami.8b07588DOI Listing
August 2018

Interaction between the Staphylococcus aureus extracellular adherence protein Eap and its subdomains with platelets.

Int J Med Microbiol 2018 Aug 18;308(6):683-691. Epub 2018 Apr 18.

Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, 17489 Greifswald, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S14384221183003
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http://dx.doi.org/10.1016/j.ijmm.2018.04.004DOI Listing
August 2018

High-Sensitivity Cardiac Troponin T: Association of Creatine Kinase Catalytic Activity With the 99 Percentile.

Clin Chem 2018 06 13;64(6):973-974. Epub 2018 Apr 13.

Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany

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http://dx.doi.org/10.1373/clinchem.2017.285775DOI Listing
June 2018

Secreted Immunomodulatory Proteins of Staphylococcus aureus Activate Platelets and Induce Platelet Aggregation.

Thromb Haemost 2018 04 19;118(4):745-757. Epub 2018 Mar 19.

Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1055/s-0038-1637735DOI Listing
April 2018

Patient was wrongly diagnosed and repeatedly treated for immune thrombocytopenia for 50 years

Lakartidningen 2018 03 13;115. Epub 2018 Mar 13.

Akademiska sjukhuset - Klinisk Immunologi och Transfusionsmedicin Uppsala, Sweden Akademiska sjukhuset - Klinisk Immunologi och Transfusionsmedicin Uppsala, Sweden.

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March 2018

Toward the Relevance of Platelet Subpopulations for Transfusion Medicine.

Front Med (Lausanne) 2018 5;5:17. Epub 2018 Feb 5.

Institut für Immunologie und Transfusionsmedizin, Greifswald, Germany.

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http://dx.doi.org/10.3389/fmed.2018.00017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807390PMC
February 2018

Release of Platelet-Derived Sphingosine-1-Phosphate Involves Multidrug Resistance Protein 4 (MRP4/ABCC4) and Is Inhibited by Statins.

Thromb Haemost 2018 01 5;118(1):132-142. Epub 2018 Jan 5.

Department of Pharmacology, Center of Drug Absorption and Transport, University Medicine Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1160/TH17-04-0291DOI Listing
January 2018

Idiopathic catastrophic thrombosis with happy ending.

BMJ Case Rep 2017 Oct 23;2017. Epub 2017 Oct 23.

Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1136/bcr-2017-221194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665346PMC
October 2017

Magnetic Nanoparticle Labeling of Human Platelets from Platelet Concentrates for Recovery and Survival Studies.

ACS Appl Mater Interfaces 2017 Oct 29;9(40):34666-34673. Epub 2017 Sep 29.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald , Sauerbruchstraße, 17475 Greifswald, Germany.

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http://dx.doi.org/10.1021/acsami.7b10113DOI Listing
October 2017

Longitudinal Changes in the Blood Supply and Demand in North-East-Germany 2005-2015.

Transfus Med Hemother 2017 Aug 27;44(4):224-231. Epub 2017 Jul 27.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1159/000479538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597943PMC
August 2017

Implementation of a rapid HIT immunoassay at a university hospital - Retrospective analysis of HIT laboratory orders in patients with thrombocytopenia.

Thromb Res 2017 Oct 15;158:65-70. Epub 2017 Aug 15.

Department of Hematology and Oncology, Internal Medicine III, University Hospital Regensburg, Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.08.008DOI Listing
October 2017

The 99th percentile and imprecision of point-of-care cardiac troponin I in comparison to central laboratory tests in a large reference population.

Clin Biochem 2017 Dec 10;50(18):1198-1202. Epub 2017 Aug 10.

Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2017.08.006DOI Listing
December 2017

Effect of pH and ionic strength on the binding strength of anti-PF4/polyanion antibodies.

Eur Biophys J 2017 Dec 15;46(8):795-801. Epub 2017 Jul 15.

ZIK HIKE-Center for Innovation Competence, Humoral Immune Reactions in Cardiovascular Diseases, Ernst-Moritz-Arndt-Universität, Greifswald, 17489, Greifswald, Germany.

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http://dx.doi.org/10.1007/s00249-017-1240-8DOI Listing
December 2017

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity.

Nat Commun 2017 05 22;8:14945. Epub 2017 May 22.

Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald 17475, Germany.

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http://dx.doi.org/10.1038/ncomms14945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458132PMC
May 2017

Altered timing of riboflavin and ultraviolet light pathogen inactivation improves platelet in vitro quality.

Transfusion 2017 08 12;57(8):2026-2034. Epub 2017 May 12.

Centre for Innovation, Canadian Blood Services, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/trf.14159DOI Listing
August 2017

Platelet factor 4/heparin complexes present epitopes differently on solid-phase vs platelet surfaces.

Blood 2017 06 5;129(26):3498-3501. Epub 2017 May 5.

Institute for Immunology and Transfusion Medicine, University Medicine Greifswald and.

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http://dx.doi.org/10.1182/blood-2017-02-769786DOI Listing
June 2017

Emergency transfusion of patients with unknown blood type with blood group O Rhesus D positive red blood cell concentrates: a prospective, single-centre, observational study.

Lancet Haematol 2017 May 4;4(5):e218-e224. Epub 2017 Apr 4.

Department of Immunology and Transfusion Medicine, University Medicine Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(17)30051-0DOI Listing
May 2017

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

PLoS One 2017 20;12(1):e0167742. Epub 2017 Jan 20.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167742PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249120PMC
August 2017

How I evaluate and treat thrombocytopenia in the intensive care unit patient.

Blood 2016 12 9;128(26):3032-3042. Epub 2016 Nov 9.

Department of Anesthesiology, University Medicine Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1182/blood-2016-09-693655DOI Listing
December 2016

Heparin-induced thrombocytopenia in 2017 and beyond.

Thromb Haemost 2016 10 13;116(5):781-782. Epub 2016 Oct 13.

Tamam Bakchoul, MD, Center for Clinical Transfusion Medicine, University Hospital of Tübingen, Otfried-Müller-Straße 4/1, 72076 Tübingen, Germany, Tel.: +49 7071 29 81601, Fax: +49 7071 29 5240, E-mail:

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http://dx.doi.org/10.1160/TH16-09-0742DOI Listing
October 2016

Biophysical tools to assess the interaction of PF4 with polyanions.

Thromb Haemost 2016 Oct 22;116(5):783-791. Epub 2016 Sep 22.

Prof. Dr. med. Andreas Greinacher, MD, Institut für Immunologie und Transfusionsmedizin, Sauerbruchstrasse, 17475 Greifswald, Germany, Tel.: +49 3834 865482, E-mail:

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http://dx.doi.org/10.1160/TH16-04-0258DOI Listing
October 2016

Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells.

Thromb Haemost 2017 01 20;117(1):105-115. Epub 2016 Oct 20.

Gabriele Jedlitschky PhD, Department of Pharmacology, Center of Drug Absorption and Transport (C_DAT), University Medicine Greifswald, Felix-Hausdorff-Str. 3, 17487 Greifswald, Germany, Tel.: +49 3834 8622146, Fax: +49 3834 865631, E-mail:

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http://dx.doi.org/10.1160/TH16-01-0045DOI Listing
January 2017

Impact of physical activity of individuals and creatine kinase on 99th percentiles of troponin I assays.

Clin Chim Acta 2016 Nov 3;462:187-192. Epub 2016 Oct 3.

Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Germany.

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http://dx.doi.org/10.1016/j.cca.2016.10.002DOI Listing
November 2016

A population-based longitudinal study on the implications of demographics on future blood supply.

Transfusion 2016 12 25;56(12):2986-2994. Epub 2016 Sep 25.

Institut für Community Medicine, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/trf.13814DOI Listing
December 2016

Letter of response to Peters and Vlaar commentary.

Transfusion 2016 09;56(9):2395-7

Ruhr University, Bochum, Germany.

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http://dx.doi.org/10.1111/trf.13747DOI Listing
September 2016

Interference of New Drugs with Compatibility Testing for Blood Transfusion.

N Engl J Med 2016 Jul;375(3):295-6

Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1056/NEJMc1515969DOI Listing
July 2016

Management of heparin-induced thrombocytopenia.

Curr Opin Hematol 2016 09;23(5):462-70

aDepartment of Pathology and Molecular Medicine; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada bInstitut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1097/MOH.0000000000000273DOI Listing
September 2016

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Authors:
Salman M Tajuddin Ursula M Schick John D Eicher Nathalie Chami Ayush Giri Jennifer A Brody W David Hill Tim Kacprowski Jin Li Leo-Pekka Lyytikäinen Ani Manichaikul Evelin Mihailov Michelle L O'Donoghue Nathan Pankratz Raha Pazoki Linda M Polfus Albert Vernon Smith Claudia Schurmann Caterina Vacchi-Suzzi Dawn M Waterworth Evangelos Evangelou Lisa R Yanek Amber Burt Ming-Huei Chen Frank J A van Rooij James S Floyd Andreas Greinacher Tamara B Harris Heather M Highland Leslie A Lange Yongmei Liu Reedik Mägi Mike A Nalls Rasika A Mathias Deborah A Nickerson Kjell Nikus John M Starr Jean-Claude Tardif Ioanna Tzoulaki Digna R Velez Edwards Lars Wallentin Traci M Bartz Lewis C Becker Joshua C Denny Laura M Raffield John D Rioux Nele Friedrich Myriam Fornage He Gao Joel N Hirschhorn David C M Liewald Stephen S Rich Andre Uitterlinden Lisa Bastarache Diane M Becker Eric Boerwinkle Simon de Denus Erwin P Bottinger Caroline Hayward Albert Hofman Georg Homuth Ethan Lange Lenore J Launer Terho Lehtimäki Yingchang Lu Andres Metspalu Chris J O'Donnell Rakale C Quarells Melissa Richard Eric S Torstenson Kent D Taylor Anne-Claire Vergnaud Alan B Zonderman David R Crosslin Ian J Deary Marcus Dörr Paul Elliott Michele K Evans Vilmundur Gudnason Mika Kähönen Bruce M Psaty Jerome I Rotter Andrew J Slater Abbas Dehghan Harvey D White Santhi K Ganesh Ruth J F Loos Tõnu Esko Nauder Faraday James G Wilson Mary Cushman Andrew D Johnson Todd L Edwards Neil A Zakai Guillaume Lettre Alex P Reiner Paul L Auer

Am J Hum Genet 2016 Jul 23;99(1):22-39. Epub 2016 Jun 23.

Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005433PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka Lyytikäinen Kjell Nikus Jussi Hernesniemi Mika Kähönen Emma Raitoharju Nina Mononen Olli T Raitakari Terho Lehtimäki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik Mägi Joel Hirschhorn Andres Metspalu Tõnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engström Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Völker Thomas Thiele Henry Völzke Frank J A van Rooij André G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre Dubé Paul Elliott Gunnar Engström Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika Kähönen Ethan Lange Lenore J Launer Terho Lehtimäki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka Lyytikäinen Reedik Mägi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup Tõnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

PDK1 Determines Collagen-Dependent Platelet Ca2+ Signaling and Is Critical to Development of Ischemic Stroke In Vivo.

Arterioscler Thromb Vasc Biol 2016 08 23;36(8):1507-16. Epub 2016 Jun 23.

From the Department of Cardiology and Cardiovascular Medicine (P.M., B.W.-A., S.G., D.R., D.E., T.G., M.G., O.B.), Department of Physiology (B.W.-A., F.L.), Department of Evolutionary Biology of Invertebrates, Institute for Evolution and Ecology (M.M.), Department of Dermatology (M.S.), and Department of Clinical Pharmacology (M.S.), University of Tübingen, Tübingen, Germany; Department of Neurology, University of Würzburg, Würzburg, Germany (E.G., C.K.); Institute for Immunology and Transfusion Medicine, University of Greifswald, Greifswald, Germany (G.H., A.G.); and Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Tübingen, Germany (S.W., E.S., M.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.307105DOI Listing
August 2016

Why is one arm stronger than two arms? IgG4 antibodies in IgG4-related autoimmune pancreatitis.

Gut 2016 08 21;65(8):1240-1. Epub 2016 Apr 21.

Institute of Immunology and Transfusion Medicine, University Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1136/gutjnl-2016-311678DOI Listing
August 2016

Reversal of dabigatran by idarucizumab: when and how?

Expert Rev Hematol 2016 Jun;9(6):519-28

a Department of Cardiovascular Sciences , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1080/17474086.2016.1184569DOI Listing
June 2016

Rupture Forces among Human Blood Platelets at different Degrees of Activation.

Sci Rep 2016 05 5;6:25402. Epub 2016 May 5.

Nanostructure Group, ZIK HIKE - Center for Innovation Competence, Humoral Immune Reactions in Cardiovascular Diseases, University of Greifswald, 17489 Greifswald, Germany.

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http://dx.doi.org/10.1038/srep25402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857101PMC
May 2016

Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations.

Transfusion 2016 06 18;56(6):1370-6. Epub 2016 Apr 18.

Institute for Immunology and Transfusion Medicine, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/trf.13602DOI Listing
June 2016

Proteomic profile of platelets during reconstitution of platelet counts after apheresis.

Proteomics Clin Appl 2016 08 17;10(8):831-8. Epub 2016 May 17.

Interfakultäres Institut für Genetik und Funktionelle Genomforschung, University Medicine Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1002/prca.201500134DOI Listing
August 2016

Interventional Endoscopy--Opportunities and Limitations.

Dtsch Arztebl Int 2016 Feb;113(8):119-20

Department of Internal Medicine A, University Medicine Greifswald, Ernst-Moritz-Arndt University of Greifswald, Department of Transfusion Medicine, Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Ernst-Moritz-Arndt University of Greifswald.

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http://dx.doi.org/10.3238/arztebl.2016.0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800156PMC
February 2016

Reduced platelet transfusions and earlier platelet engraftment using alemtuzumab-based conditioning regimen in allogeneic stem cell transplantation.

J Cancer Res Clin Oncol 2016 May 16;142(5):1091-7. Epub 2016 Jan 16.

Department of Hematology, Oncology, Transplantation, University Medical Center, Ernst-Moritz-Arndt University, Greifswald, Germany.

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http://dx.doi.org/10.1007/s00432-016-2114-7DOI Listing
May 2016

Hemostatic management of patients undergoing ear-nose-throat surgery.

GMS Curr Top Otorhinolaryngol Head Neck Surg 2015 22;14:Doc07. Epub 2015 Dec 22.

Institute for Immunology and Transfusion Medicine, Section of Transfusion Medicine, University Medicine of Greifswald, Germany.

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http://dx.doi.org/10.3205/cto000122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702056PMC
January 2016

'Chameleonic' Serological Findings Leading to Life-Threatening Hemolytic Transfusion Reactions.

Transfus Med Hemother 2015 Sep 4;42(5):340-3. Epub 2015 Aug 4.

Institute for Transfusion Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1159/000437198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678317PMC
September 2015

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

Authors:
Paul S de Vries Daniel I Chasman Maria Sabater-Lleal Ming-Huei Chen Jennifer E Huffman Maristella Steri Weihong Tang Alexander Teumer Riccardo E Marioni Vera Grossmann Jouke J Hottenga Stella Trompet Martina Müller-Nurasyid Jing Hua Zhao Jennifer A Brody Marcus E Kleber Xiuqing Guo Jie Jin Wang Paul L Auer John R Attia Lisa R Yanek Tarunveer S Ahluwalia Jari Lahti Cristina Venturini Toshiko Tanaka Lawrence F Bielak Peter K Joshi Ares Rocanin-Arjo Ivana Kolcic Pau Navarro Lynda M Rose Christopher Oldmeadow Helene Riess Johanna Mazur Saonli Basu Anuj Goel Qiong Yang Mohsen Ghanbari Gonneke Willemsen Ann Rumley Edoardo Fiorillo Anton J M de Craen Anne Grotevendt Robert Scott Kent D Taylor Graciela E Delgado Jie Yao Annette Kifley Charles Kooperberg Rehan Qayyum Lorna M Lopez Tina L Berentzen Katri Räikkönen Massimo Mangino Stefania Bandinelli Patricia A Peyser Sarah Wild David-Alexandre Trégouët Alan F Wright Jonathan Marten Tatijana Zemunik Alanna C Morrison Bengt Sennblad Geoffrey Tofler Moniek P M de Maat Eco J C de Geus Gordon D Lowe Magdalena Zoledziewska Naveed Sattar Harald Binder Uwe Völker Melanie Waldenberger Kay-Tee Khaw Barbara Mcknight Jie Huang Nancy S Jenny Elizabeth G Holliday Lihong Qi Mark G Mcevoy Diane M Becker John M Starr Antti-Pekka Sarin Pirro G Hysi Dena G Hernandez Min A Jhun Harry Campbell Anders Hamsten Fernando Rivadeneira Wendy L Mcardle P Eline Slagboom Tanja Zeller Wolfgang Koenig Bruce M Psaty Talin Haritunians Jingmin Liu Aarno Palotie André G Uitterlinden David J Stott Albert Hofman Oscar H Franco Ozren Polasek Igor Rudan Pierre-Emmanuel Morange James F Wilson Sharon L R Kardia Luigi Ferrucci Tim D Spector Johan G Eriksson Torben Hansen Ian J Deary Lewis C Becker Rodney J Scott Paul Mitchell Winfried März Nick J Wareham Annette Peters Andreas Greinacher Philipp S Wild J Wouter Jukema Dorret I Boomsma Caroline Hayward Francesco Cucca Russell Tracy Hugh Watkins Alex P Reiner Aaron R Folsom Paul M Ridker Christopher J O'Donnell Nicholas L Smith David P Strachan Abbas Dehghan

Hum Mol Genet 2016 Jan 10;25(2):358-70. Epub 2015 Nov 10.

Department of Epidemiology,

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http://hmg.oxfordjournals.org/content/early/2015/12/08/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715256PMC
January 2016

Heparin-Induced Thrombocytopenia.

N Engl J Med 2015 11;373(19):1883-4

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http://dx.doi.org/10.1056/NEJMc1510993DOI Listing
November 2015

Further insights into the anti-PF4/heparin IgM immune response.

Thromb Haemost 2016 Apr 15;115(4):752-61. Epub 2015 Oct 15.

Prof. Dr. Andreas Greinacher, Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Ferdinand-Sauerbruch-Strasse, D-17489 Greifswald, Germany, Tel.: +49 3834 865482, Fax: +49 3834 865489, E-mail:

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http://dx.doi.org/10.1160/TH15-08-0654DOI Listing
April 2016

Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils.

Clin Chim Acta 2015 Dec 3;451(Pt B):199-207. Epub 2015 Oct 3.

Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Friedrich-Ludwig-Jahn-Straße 15A, D-17475 Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2015.09.030DOI Listing
December 2015

Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets.

Thromb Haemost 2016 Jan 1;115(2):324-32. Epub 2015 Oct 1.

Tamam Bakchoul, MD, Institute for Immunology and Transfusion Medicine, Universitätsmedizin Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany, Tel.: +49 3834 865458, Fax: +49 3834 865489, E-mail:

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http://dx.doi.org/10.1160/TH15-07-0539DOI Listing
January 2016

Human neutrophil antigen-3a antibodies induce neutrophil stiffening and conformational activation of CD11b without shedding of L-selectin.

Transfusion 2015 Dec 10;55(12):2939-48. Epub 2015 Sep 10.

Nanostructure Group, ZIK HIKE-Center for Innovation Competence, Humoral Immune Reactions in Cardiovascular Diseases, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1111/trf.13299DOI Listing
December 2015

Flucloxacillin-induced immune thrombocytopenia.

Transfusion 2016 Jan 1;56(1):67-72. Epub 2015 Sep 1.

Institut for Immunology and Transfusion Medicine, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://doi.wiley.com/10.1111/trf.13284
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http://dx.doi.org/10.1111/trf.13284DOI Listing
January 2016

Thrombin generation in two families with MYH9-related platelet disorder.

Platelets 2016 6;27(3):264-7. Epub 2015 Aug 6.

d Institute of Immunology and Transfusion Medicine , Greifswald , Germany.

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http://dx.doi.org/10.3109/09537104.2015.1064882DOI Listing
December 2016

Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria.

Thromb Haemost 2015 Nov 30;114(6):1189-98. Epub 2015 Jul 30.

Prof. Dr. med. Andreas Greinacher, MD, Institut für Immunologie und Transfusionsmedizin, Sauerbruchstrasse, 17475 Greifswald, Germany, Tel.: +49 3834 865482, E-mail:

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http://dx.doi.org/10.1160/TH15-01-0062DOI Listing
November 2015