Andreas Fritsche

Andreas Fritsche

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Andreas Fritsche

Andreas Fritsche

Publications by authors named "Andreas Fritsche"

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Visceral Adiposity Index as an Independent Marker of Subclinical Atherosclerosis in Individuals Prone to Diabetes Mellitus.

J Atheroscler Thromb 2019 Sep 19;26(9):821-834. Epub 2019 Feb 19.

Department of Internal Medicine IV, Division of Endocrinology and Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University Hospital of Tübingen.

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http://dx.doi.org/10.5551/jat.47274DOI Listing
September 2019

Predictors of treatment response in type-2 diabetes patients initiating basal-supported oral therapy with insulin glargine 100 U/mL: A sub-analysis of the Titration and OPtimisation (TOP) registry.

Diabetes Obes Metab 2019 Sep 29;21(9):2169-2173. Epub 2019 May 29.

Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.

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http://dx.doi.org/10.1111/dom.13768DOI Listing
September 2019

AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism.

J Clin Endocrinol Metab 2019 Sep 12. Epub 2019 Sep 12.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1210/jcem/dgz020DOI Listing
September 2019

AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism.

J Clin Endocrinol Metab 2019 Sep 12. Epub 2019 Sep 12.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1210/clinem/dgz020DOI Listing
September 2019

HbA1c target achievement in the elderly: results of the Titration and Optimization trial for initiation of insulin glargine 100 U/mL in patients with type 2 diabetes poorly controlled on oral antidiabetic drugs.

BMJ Open Diabetes Res Care 2019 1;7(1):e000668. Epub 2019 Aug 1.

Abteilung Endokrinologie und Diabetologie, Klinik für Innere Medizin II, Medizinische Fakultät, Albert-Ludwig-Universität Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1136/bmjdrc-2019-000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688703PMC
August 2019

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibition in Kidney Transplant Recipients with Diabetes Mellitus.

Kidney Blood Press Res 2019 Aug 22:1-9. Epub 2019 Aug 22.

Department of Diabetology, Endocrinology, Nephrology, Section of Nephrology and Hypertension, University of Tübingen, Tübingen, Germany,

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http://dx.doi.org/10.1159/000501854DOI Listing
August 2019

What role do fat cells play in pancreatic tissue?

Mol Metab 2019 Jul 7;25:1-10. Epub 2019 May 7.

German Center for Diabetes Research (DZD), Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases, Helmholtz Center Munich, Eberhard Karls University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600604PMC
July 2019

Functional Connectivity Within the Gustatory Network Is Altered by Fat Content and Oral Fat Sensitivity - A Pilot Study.

Front Neurosci 2019 10;13:725. Epub 2019 Jul 10.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, German Center for Diabetes Research (DZD), Tübingen, Germany.

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http://dx.doi.org/10.3389/fnins.2019.00725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636204PMC
July 2019

Fatty Acid-Binding Protein 4 and Risk of Type 2 Diabetes, Myocardial Infarction and Stroke: A Prospective Cohort Study.

J Clin Endocrinol Metab 2019 Jun 18. Epub 2019 Jun 18.

Molecular Epidemiology Research Group, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.

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http://dx.doi.org/10.1210/jc.2019-00477DOI Listing
June 2019

Health, pleasure, and fullness: changing mindset affects brain responses and portion size selection in adults with overweight and obesity.

Int J Obes (Lond) 2019 Jun 18. Epub 2019 Jun 18.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen; German Center for Diabetes Research (DZD e.V.), Tübingen, Germany.

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http://dx.doi.org/10.1038/s41366-019-0400-6DOI Listing
June 2019

Metabolomic Characteristics of Fatty Pancreas.

Exp Clin Endocrinol Diabetes 2019 May 16. Epub 2019 May 16.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1055/a-0896-8671DOI Listing
May 2019

Effect of SGLT2 inhibitors on body composition, fluid status and renin-angiotensin-aldosterone system in type 2 diabetes: a prospective study using bioimpedance spectroscopy.

Cardiovasc Diabetol 2019 04 5;18(1):46. Epub 2019 Apr 5.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University Hospital Tübingen, Otfried-Müller-Str.10, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1186/s12933-019-0852-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451223PMC
April 2019

Association of Chemerin Plasma Concentration With Risk of Colorectal Cancer.

JAMA Netw Open 2019 Mar 1;2(3):e190896. Epub 2019 Mar 1.

Senior Scientist Group Nutrition, Immunity and Metabolism, Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.0896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583278PMC
March 2019

Sex-Specific Associations of Testosterone With Metabolic Traits.

Front Endocrinol (Lausanne) 2019 13;10:90. Epub 2019 Mar 13.

Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fendo.2019.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425082PMC
March 2019

Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin.

Mol Metab 2019 02 26;20:28-37. Epub 2018 Nov 26.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.molmet.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358537PMC
February 2019

Gene x Gene Interactions Highlight the Role of Incretin Resistance for Insulin Secretion.

Front Endocrinol (Lausanne) 2019 21;10:72. Epub 2019 Feb 21.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fendo.2019.00072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393347PMC
February 2019

Genetic variation in TCF7L2 rs7903146 and history of GDM negatively and independently impact on diabetes-associated metabolic traits.

Diabetes Res Clin Pract 2018 Dec 10;146:251-257. Epub 2018 Nov 10.

German Center for Diabetes Research (DZD), Neuherberg, Germany; Diabetes Research Group, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany; Clinical Cooperation Group Type 2 Diabetes, Helmholtz Center Munich, Neuherberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01688227183092
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http://dx.doi.org/10.1016/j.diabres.2018.11.003DOI Listing
December 2018

Nasal insulin administration does not affect hepatic glucose production at systemic fasting insulin levels.

Diabetes Obes Metab 2018 Dec 15. Epub 2018 Dec 15.

Institute for Diabetes Research and Metabolic Diseases, Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tuebingen, Tuebingen, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/dom.13615
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http://dx.doi.org/10.1111/dom.13615DOI Listing
December 2018

Periaortic Adipose Tissue Compared With Peribrachial Adipose Tissue Mass as Markers and Possible Modulators of Cardiometabolic Risk.

Angiology 2018 11 14;69(10):854-860. Epub 2018 Feb 14.

1 Division of Endocrinology and Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Department of Internal Medicine IV, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1177/0003319718755581DOI Listing
November 2018

Treatment of malnutrition decreases complication rates and shortens the length of hospital stays in a radiation oncology department.

Strahlenther Onkol 2018 Nov 4;194(11):1049-1059. Epub 2018 Sep 4.

Nutrition Support Team, University Hospital Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1007/s00066-018-1360-9DOI Listing
November 2018

Family History of Diabetes Is Associated With Delayed Fetal Postprandial Brain Activity.

Front Endocrinol (Lausanne) 2018 20;9:673. Epub 2018 Nov 20.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fendo.2018.00673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256935PMC
November 2018

BMI-Independent Effects of Gestational Diabetes on Human Placenta.

J Clin Endocrinol Metab 2018 09;103(9):3299-3309

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Zentrum München at Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1210/jc.2018-00397DOI Listing
September 2018

Unusual high blood glucose in ketoacidosis as first presentation of type 1 diabetes mellitus

Endocrinol Diabetes Metab Case Rep 2018 Sep 25;2018. Epub 2018 Sep 25.

Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Tübingen, Germany

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https://edm.bioscientifica.com/view/journals/edm/2018/1/EDM1
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http://dx.doi.org/10.1530/EDM-18-0094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169544PMC
September 2018

Switching to insulin glargine 300 U/mL: Is duration of prior basal insulin therapy important?

Diabetes Res Clin Pract 2018 Aug 9;142:19-25. Epub 2018 Apr 9.

Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2018.03.041DOI Listing
August 2018

Effects of resveratrol supplementation on liver fat content in overweight and insulin-resistant subjects: A randomized, double-blind, placebo-controlled clinical trial.

Diabetes Obes Metab 2018 07 22;20(7):1793-1797. Epub 2018 Mar 22.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1111/dom.13268DOI Listing
July 2018

Safety of intranasal human insulin: A review.

Diabetes Obes Metab 2018 07 6;20(7):1563-1577. Epub 2018 Apr 6.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center, Munich, at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1111/dom.13279DOI Listing
July 2018

Dynamics of Glucose Metabolism After Kidney Transplantation.

Kidney Blood Press Res 2017 20;42(3):598-607. Epub 2017 Sep 20.

Dept. of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1159/000481375DOI Listing
June 2018

Eating less or more - Mindset induced changes in neural correlates of pre-meal planning.

Appetite 2018 06 7;125:492-501. Epub 2018 Mar 7.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany; Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Interfaculty Centre for Pharmacogenomics and Pharma Research, Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2018.03.006DOI Listing
June 2018

A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes.

Mol Metab 2018 05 15;11:145-159. Epub 2018 Mar 15.

German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, 14558, Nuthetal, Germany; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183013
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http://dx.doi.org/10.1016/j.molmet.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001404PMC
May 2018

Detection thresholds for four different fatty stimuli are associated with increased dietary intake of processed high-caloric food.

Appetite 2018 04 5;123:7-13. Epub 2017 Dec 5.

Centre for Advanced Sensory Sciences, School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, Victoria, 3125, Australia.

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http://dx.doi.org/10.1016/j.appet.2017.12.003DOI Listing
April 2018

Leptin Replacement Reestablishes Brain Insulin Action in the Hypothalamus in Congenital Leptin Deficiency.

Diabetes Care 2018 04 24;41(4):907-910. Epub 2018 Jan 24.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, German Center for Diabetes Research, Tübingen, Germany.

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http://dx.doi.org/10.2337/dc17-1867DOI Listing
April 2018

The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans.

Am J Physiol Endocrinol Metab 2018 03 14;314(3):E266-E273. Epub 2017 Nov 14.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University of Tübingen , Tübingen , Germany.

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http://www.physiology.org/doi/10.1152/ajpendo.00262.2017
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http://dx.doi.org/10.1152/ajpendo.00262.2017DOI Listing
March 2018

Higher prevalence of lymph node metastasis in prostate cancer in patients with diabetes.

Endocr Relat Cancer 2018 03 12;25(3):L19-L22. Epub 2018 Jan 12.

Department of Internal MedicineDivision of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1530/ERC-17-0465DOI Listing
March 2018

Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test.

Front Endocrinol (Lausanne) 2018 19;9:82. Epub 2018 Mar 19.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fendo.2018.00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868129PMC
March 2018

Prevalence and Distribution of Diabetes Mellitus in a Maximum Care Hospital: Urgent Need for HbA1c-Screening.

Exp Clin Endocrinol Diabetes 2018 02 27;126(2):123-129. Epub 2017 Jul 27.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany.

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http://dx.doi.org/10.1055/s-0043-112653DOI Listing
February 2018

Androgen receptor overexpression in prostate cancer in type 2 diabetes.

Mol Metab 2018 02 5;8:158-166. Epub 2017 Dec 5.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University of Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases (IDM), Helmholtz Center Munich, University of Tübingen, Germany; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.molmet.2017.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985051PMC
February 2018

Dose-Dependent Effects of Intranasal Insulin on Resting-State Brain Activity.

J Clin Endocrinol Metab 2018 01;103(1):253-262

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1210/jc.2017-01976DOI Listing
January 2018

Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion.

Diabetologia 2017 Nov 8;60(11):2240-2251. Epub 2017 Aug 8.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the Eberhard Karls University of Tuebingen (IDM), Tuebingen, Germany.

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http://dx.doi.org/10.1007/s00125-017-4385-1DOI Listing
November 2017

Excessive fuel availability amplifies the FTO-mediated obesity risk: results from the TUEF and Whitehall II studies.

Sci Rep 2017 11 14;7(1):15486. Epub 2017 Nov 14.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41598-017-15744-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686126PMC
November 2017

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease.

Mol Metab 2017 10 4;6(10):1254-1263. Epub 2017 Aug 4.

German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, Potsdam-Rehbruecke, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641684PMC
October 2017

FTO Genotype Interacts with Improvement in Aerobic Fitness on Body Weight Loss During Lifestyle Intervention.

Obes Facts 2016 4;9(3):174-81. Epub 2016 Jun 4.

Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tx00FC;bingen, Tx00FC;bingen, Germany.

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http://dx.doi.org/10.1159/000444145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644850PMC
September 2017

Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations.

PLoS One 2017 4;12(5):e0177148. Epub 2017 May 4.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the Eberhard Karls University Tübingen, Otfried-Müller-Straße 10, Tübingen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177148PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417681PMC
September 2017

Intra- and interindividual variability of fatty acid unsaturation in six different human adipose tissue compartments assessed by H-MRS in vivo at 3 T.

NMR Biomed 2017 Sep 25;30(9). Epub 2017 May 25.

Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Germany.

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http://dx.doi.org/10.1002/nbm.3744DOI Listing
September 2017

Oil Perception-Detection Thresholds for Varying Fatty Stimuli and Inter-individual Differences.

Chem Senses 2017 Sep;42(7):585-592

Centre for Advanced Sensory Sciences, School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, Victoria, 3125, Australia.

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http://dx.doi.org/10.1093/chemse/bjx039DOI Listing
September 2017

[Implementation of the National Guidelines for the treatment of Diabetes mellitus type 2 in secondary diabetes centers].

Dtsch Med Wochenschr 2017 Sep 8;142(18):e131-e139. Epub 2017 Sep 8.

Deutsches Zentrum für Diabetesforschung (DZD), Institut für Diabetesforschung und Metabolische Erkrankungen des Helmholtz Zentrums München an der Eberhard Karls Universität, Tübingen.

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http://dx.doi.org/10.1055/s-0043-111388DOI Listing
September 2017

Sustained Treatment with Insulin Detemir in Mice Alters Brain Activity and Locomotion.

PLoS One 2016 2;11(9):e0162124. Epub 2016 Sep 2.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University of Tuebingen, Tuebingen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162124PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010192PMC
August 2017

Patients' preferences for involvement in the decision-making process for treating diabetic retinopathy.

BMC Ophthalmol 2017 Aug 9;17(1):139. Epub 2017 Aug 9.

Center for Ophthalmology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1186/s12886-017-0526-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551005PMC
August 2017

Hypothalamic and Striatal Insulin Action Suppresses Endogenous Glucose Production and May Stimulate Glucose Uptake During Hyperinsulinemia in Lean but Not in Overweight Men.

Diabetes 2017 07 7;66(7):1797-1806. Epub 2017 Feb 7.

Division of Endocrinology, Diabetology, Angiology, Nephrology, and Clinical Chemistry, Department of Internal Medicine, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.2337/db16-1380DOI Listing
July 2017

Hypothalamic insulin responsiveness is associated with pancreatic insulin secretion in humans.

Physiol Behav 2017 Jul 24;176:134-138. Epub 2017 Mar 24.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.physbeh.2017.03.036DOI Listing
July 2017

Erratum to: A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.

Acta Diabetol 2017 07;54(7):713-714

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00592-017-1002-1DOI Listing
July 2017

Genetic determination of body fat distribution and the attributive influence on metabolism.

Obesity (Silver Spring) 2017 07 25;25(7):1277-1283. Epub 2017 May 25.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University, Tübingen, Germany.

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http://dx.doi.org/10.1002/oby.21874DOI Listing
July 2017

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance.

Diabetes 2017 05 16;66(5):1373-1379. Epub 2016 Dec 16.

Division of Endocrinology, Diabetology, Nephrology, Vascular Disease, and Clinical Chemistry, Department of Internal Medicine, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany

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http://dx.doi.org/10.2337/db16-0354DOI Listing
May 2017

Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger.

Sci Rep 2017 05 9;7(1):1627. Epub 2017 May 9.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41598-017-01907-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431641PMC
May 2017

Impact of end-stage renal disease on glucose metabolism-a matched cohort analysis.

Nephrol Dial Transplant 2017 04;32(4):670-676

Department of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1093/ndt/gfx018DOI Listing
April 2017

Plasma osteoprotegerin, its correlates, and risk of heart failure: a prospective cohort study.

Eur J Epidemiol 2017 02 15;32(2):113-123. Epub 2016 Jun 15.

Research Group Cardiovascular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee, 114-116, 14558, Nuthetal, Germany.

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http://dx.doi.org/10.1007/s10654-016-0172-4DOI Listing
February 2017

Limited Time from the Diabetes Patients' Perspective: Need for Conversation with the Eye Specialist.

Ophthalmologica 2016 5;236(3):154-158. Epub 2016 Oct 5.

Center for Ophthalmology, Eberhard Karl University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1159/000450708DOI Listing
January 2017

Soluble urokinase receptor (suPAR) predicts microalbuminuria in patients at risk for type 2 diabetes mellitus.

Sci Rep 2017 01 16;7:40627. Epub 2017 Jan 16.

Dept. of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Otfried-Müller-Str. 10, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1038/srep40627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238426PMC
January 2017

Interaction between the obesity-risk gene FTO and the dopamine D2 receptor gene ANKK1/TaqIA on insulin sensitivity.

Diabetologia 2016 12 6;59(12):2622-2631. Epub 2016 Sep 6.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00125-016-4095-0DOI Listing
December 2016

Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity.

J Clin Endocrinol Metab 2016 12 7;101(12):4743-4751. Epub 2016 Oct 7.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry (S.Z.L., A.P., F.M., A.L., A.F., H.-U.H., N.S., K.K.), Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich (S.Z.L., A.P., F.M., A.L., J.M., F.S., A.F., H.S., H.-U.H., N.S., K.K.), Section on Experimental Radiology (J.M., F.S.), Department of General, Visceral, and Transplant Surgery (I.K., A.K.), and Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry (H.S.), University of Tübingen, D-72076 Tübingen, Germany; German Center for Diabetes Research (S.Z.L., A.P., F.M., A.L., J.M., F.S., A.F., H.S., H.-U.H., N.S., K.K.), 85764 München-Neuherberg, Germany.

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http://dx.doi.org/10.1210/jc.2016-2498DOI Listing
December 2016

A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.

Acta Diabetol 2016 Dec 22;53(6):1037-1044. Epub 2016 Oct 22.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00592-016-0930-5DOI Listing
December 2016

The impact of insulin resistance on the kidney and vasculature.

Nat Rev Nephrol 2016 Dec 17;12(12):721-737. Epub 2016 Oct 17.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University Hospital Tübingen, Otfried-Mueller-Strasse 10, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1038/nrneph.2016.145DOI Listing
December 2016

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle.

Diabetes 2016 10 29;65(10):2849-61. Epub 2016 Jun 29.

Division of Endocrinology, Diabetology, Angiology, Nephrology, Pathobiochemistry and Clinical Chemistry, Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Zentrum München, University of Tübingen, Tübingen, Germany German Center for Diabetes Research (DZD), Neuherberg, Germany

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http://dx.doi.org/10.2337/db15-1723DOI Listing
October 2016

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.

Diabetes 2016 10 14;65(10):3200-11. Epub 2016 Jul 14.

Diabetes Research Center (Diabetes Unit), Massachusetts General Hospital, Boston, MA Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA Department of Medicine, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.2337/db16-0199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033262PMC
October 2016

Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans.

Physiol Rev 2016 10 3;96(4):1169-209. Epub 2016 Aug 3.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), Tübingen, Germany; Department of Internal Medicine IV, University of Tübingen, Tübingen, Germany; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany; and Department of Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1152/physrev.00032.2015DOI Listing
October 2016

Phenotypes of prediabetes and stratification of cardiometabolic risk.

Lancet Diabetes Endocrinol 2016 09 13;4(9):789-798. Epub 2016 May 13.

Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany; German Centre for Diabetes Research (DZD), Tübingen, Germany.

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http://dx.doi.org/10.1016/S2213-8587(16)00082-6DOI Listing
September 2016

Neuronal Food Reward Activity in Patients With Type 2 Diabetes With Improved Glycemic Control After Bariatric Surgery.

Diabetes Care 2016 Aug 12;39(8):1311-7. Epub 2016 Jun 12.

Department of Internal Medicine IV, University Hospital, Tübingen, Germany German Center for Diabetes Research, München-Neuherberg, Germany Department of Pharmacy and Biochemistry, Faculty of Science, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.2337/dc16-0094DOI Listing
August 2016

Omentin-1 and risk of myocardial infarction and stroke: Results from the EPIC-Potsdam cohort study.

Atherosclerosis 2016 08 2;251:415-421. Epub 2016 Jun 2.

Research Group Cardiovascular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany; German Center for Cardiovascular Disease (DZHK), Germany; Federal Institute for Risk Assessment, Department of Food Safety, Berlin, Germany.

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.06.003DOI Listing
August 2016

Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice.

Hum Mol Genet 2016 06 28;25(12):2588-2599. Epub 2016 Apr 28.

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.

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http://dx.doi.org/10.1093/hmg/ddw121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181631PMC
June 2016

Omentin-1, Adiponectin, and the Risk of Developing Type 2 Diabetes.

Diabetes Care 2016 06 18;39(6):e79-80. Epub 2016 Apr 18.

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany German Center for Diabetes Research (DZD), München-Neuherberg, Germany

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http://dx.doi.org/10.2337/dc15-2702DOI Listing
June 2016

Dopamine Depletion Reduces Food-Related Reward Activity Independent of BMI.

Neuropsychopharmacology 2016 May 9;41(6):1551-9. Epub 2015 Oct 9.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.

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http://www.nature.com/articles/npp2015313
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http://dx.doi.org/10.1038/npp.2015.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832016PMC
May 2016

Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans.

Mol Metab 2016 Apr 13;5(4):305-316. Epub 2016 Feb 13.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Tübingen, Germany; Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, University Hospital Tübingen, Tübingen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778160002
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http://dx.doi.org/10.1016/j.molmet.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812007PMC
April 2016

Specific white matter tissue microstructure changes associated with obesity.

Neuroimage 2016 Jan 13;125:36-44. Epub 2015 Oct 13.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research, Tübingen, Germany; Department of Internal Medicine IV, University of Tübingen, Germany; Department Pharmacy and Biochemistry, Faculty of Science, Eberhard Karls Universität Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.neuroimage.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692452PMC
January 2016

The Medically Complex Living Kidney Donor: Glucose Metabolism as Principal Cause of Donor Declination.

Ann Transplant 2016 Jan 26;21:39-45. Epub 2016 Jan 26.

Department of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.12659/aot.895729DOI Listing
January 2016

A high-risk phenotype associates with reduced improvement in glycaemia during a lifestyle intervention in prediabetes.

Diabetologia 2015 Dec 24;58(12):2877-84. Epub 2015 Sep 24.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University Hospital Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Germany.

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http://link.springer.com/10.1007/s00125-015-3760-z
Publisher Site
http://dx.doi.org/10.1007/s00125-015-3760-zDOI Listing
December 2015

Impaired insulin action in the human brain: causes and metabolic consequences.

Nat Rev Endocrinol 2015 Dec 13;11(12):701-11. Epub 2015 Oct 13.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University, Partners in the German Centre for Diabetes Research (DZD), Otfried-Müller-Street 10, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1038/nrendo.2015.173DOI Listing
December 2015

Dissociation of GLP-1 and insulin association with food processing in the brain: GLP-1 sensitivity despite insulin resistance in obese humans.

Mol Metab 2015 Dec 30;4(12):971-6. Epub 2015 Sep 30.

Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.molmet.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731733PMC
December 2015

Gestational Diabetes Impairs Human Fetal Postprandial Brain Activity.

J Clin Endocrinol Metab 2015 11 14;100(11):4029-36. Epub 2015 Oct 14.

Department of Internal Medicine (K.L., M.H., H.-U.H., A.F.), Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, University Hospital Tübingen, Tübingen, Germany; fMEG Center, University of Tübingen (F.S., I.K.-S., S.K., M.W., H.P.), Tübingen, Germany; German Center for Diabetes Research, Neuherberg, Germany (K.L., F.S., L.F., M.H., H.-U.H., H.P., A.F.); Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen (K.L., F.S., L.F., M.H., H.-U.H., H.P., A.F.), Tübingen, Germany; Department of Obstetrics and Gynecology (I.K.-S.), University Hospital Tübingen, Tübingen, Germany; Department of Pharmacy and Biochemistry (H.P.), Faculty of Science, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1210/jc.2015-2692DOI Listing
November 2015