Andreas E Kremer

Andreas E Kremer

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Andreas E Kremer

Andreas E Kremer

Publications by authors named "Andreas E Kremer"

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54Publications

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Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure.

Authors:
Miriam Bittel Andreas E Kremer Michael Stürzl Stefan Wirtz Iris Stolzer Markus F Neurath Gianna Ballon Claudia Günther

Cell Death Dis 2019 Nov 21;10(12):878. Epub 2019 Nov 21.

Department of Medicine 1, University hospital, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41419-019-2115-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872756PMC
November 2019

Antipruritic effect of bezafibrate and serum autotaxin measures in patients with primary biliary cholangitis.

Authors:
Andreas E Kremer Aline Le Cleac'h Sara Lemoinne Katharina Wolf Luc De Chaisemartin Sylvie Chollet-Martin Lydie Humbert Dominique Rainteau Raoul Poupon Alexandra Rousseau Olivier Chazouillères Christophe Corpechot

Gut 2019 10 18;68(10):1902-1903. Epub 2018 Sep 18.

Reference Center for Inflammatory Biliary Diseases and Autoimmune Hepatitis, Saint-Antoine Hospital, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France.

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http://dx.doi.org/10.1136/gutjnl-2018-317426DOI Listing
October 2019

Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial.

Authors:
Stefan Traussnigg Jörn M Schattenberg Münevver Demir Johannes Wiegand Andreas Geier Gerlinde Teuber Wolf Peter Hofmann Andreas E Kremer Frank Spreda Johannes Kluwe Jörg Petersen Tobias Boettler Florian Rainer Emina Halilbasic Roland Greinwald Markus Pröls Michael P Manns Peter Fickert Michael Trauner

Lancet Gastroenterol Hepatol 2019 Oct 22;4(10):781-793. Epub 2019 Jul 22.

Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30184-0DOI Listing
October 2019

Long-term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis.

Authors:
Christopher L Bowlus Paul J Pockros Andreas E Kremer Albert Parés Lisa M Forman Joost P H Drenth Stephen D Ryder Luigi Terracciano Yuying Jin Alexander Liberman Richard Pencek Uche Iloeje Leigh MacConell Pierre Bedossa

Clin Gastroenterol Hepatol 2019 Oct 10. Epub 2019 Oct 10.

Department of Pathology, Physiology and Imaging, University Paris Diderot, Paris, France.

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http://dx.doi.org/10.1016/j.cgh.2019.09.050DOI Listing
October 2019

What are new treatment concepts in systemic itch?

Authors:
Andreas E Kremer

Exp Dermatol 2019 Aug 27. Epub 2019 Aug 27.

Department of Medicine 1 & Translational Research Center, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/exd.14024DOI Listing
August 2019

Peripheral Sensitization and Loss of Descending Inhibition Is a Hallmark of Chronic Pruritus.

Authors:
Esther M Pogatzki-Zahn Manuel P Pereira Alexander Cremer Claudia Zeidler Tim Dreyer Claudia Riepe Carola Wempe Tobias Lotts Daniel Segelcke Matthias Ringkamp Andreas E Kremer Konstantin Agelopoulos Sonja Ständer

J Invest Dermatol 2019 Jul 2. Epub 2019 Jul 2.

Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, North Rhine-Westphalia, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.05.029DOI Listing
July 2019

Treatment of Pruritus Secondary to Liver Disease.

Authors:
Miriam M Düll Andreas E Kremer

Curr Gastroenterol Rep 2019 Jul 31;21(9):48. Epub 2019 Jul 31.

Department of Medicine 1, Gastroenterology, Hepatology, Pneumology and Endocrinology, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, D-91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s11894-019-0713-6DOI Listing
July 2019

A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats.

Authors:
Claudia Einer Christin Leitzinger Josef Lichtmannegger Carola Eberhagen Tamara Rieder Sabine Borchard Ralf Wimmer Gerald Denk Bastian Popper Frauke Neff Elena V Polishchuk Roman S Polishchuk Stefanie M Hauck Christine von Toerne Jennifer-Christin Müller Uwe Karst Bipin S Baral Alan A DiSpirito Andreas E Kremer Jeremy Semrau Karl Heinz Weiss Simon Hohenester Hans Zischka

Cell Mol Gastroenterol Hepatol 2019 23;7(3):571-596. Epub 2018 Dec 23.

Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Toxicology and Environmental Hygiene, Technical University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407159PMC
June 2019

Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis.

Authors:
Amandeep K Dhillon Andreas E Kremer Martin Kummen Kirsten M Boberg Ronald P Oude Elferink Tom H Karlsen Ulrich Beuers Mette Vesterhus Johannes R Hov

Sci Rep 2019 Jun 11;9(1):8450. Epub 2019 Jun 11.

Norwegian PSC Research Center, Department of transplantation medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1038/s41598-019-44762-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559994PMC
June 2019

Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients.

Authors:
Monika Rau Johannes Schmitt Thomas Berg Andreas E Kremer Bruno Stieger Katharina Spanaus Bertram Bengsch Marta R Romero Jose J Marin Verena Keitel Hartwig Klinker Hans-Peter Tony Beat Müllhaupt Andreas Geier

PLoS One 2018 3;13(12):e0208225. Epub 2018 Dec 3.

Division of Hepatology, Department of Medicine II, University Hospital Würzburg, Würzburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208225PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277069PMC
May 2019

Lysophosphatidic acid activates satellite glia cells and Schwann cells.

Authors:
Jan W Robering Lisa Gebhardt Katharina Wolf Helen Kühn Andreas E Kremer Michael J M Fischer

Glia 2019 05 13;67(5):999-1012. Epub 2019 Jan 13.

Institute of Physiology and Pathophysiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/glia.23585DOI Listing
May 2019

Effects of Vedolizumab in Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases.

Authors:
Kate D Lynch Roger W Chapman Satish Keshav Aldo J Montano-Loza Andrew L Mason Andreas E Kremer Marcel Vetter Manon de Krijger Cyriel Y Ponsioen Palak Trivedi Gideon Hirschfield Christoph Schramm Chung Heng Liu Christopher L Bowlus Derek J Estes Daniel Pratt Charlotte Hedin Annika Bergquist Annemarie C de Vries C Janneke van der Woude Lei Yu David N Assis James Boyer Henriette Ytting Emina Hallibasic Michael Trauner Hanns-Ulrich Marschall Luigi M Daretti Marco Marzioni Kidist K Yimam Nicola Perin Annarosa Floreani Benedetta Terziroli Beretta-Piccoli Jennifer K Rogers Cynthia Levy

Clin Gastroenterol Hepatol 2019 May 14. Epub 2019 May 14.

Division of Hepatology, University of Miami, Miami, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.05.013DOI Listing
May 2019

PU.1 controls fibroblast polarization and tissue fibrosis.

Authors:
Thomas Wohlfahrt Simon Rauber Steffen Uebe Markus Luber Alina Soare Arif Ekici Stefanie Weber Alexandru-Emil Matei Chih-Wei Chen Christiane Maier Emmanuel Karouzakis Hans P Kiener Elena Pachera Clara Dees Christian Beyer Christoph Daniel Kolja Gelse Andreas E Kremer Elisabeth Naschberger Michael Stürzl Falk Butter Michael Sticherling Susetta Finotto Alexander Kreuter Mark H Kaplan Astrid Jüngel Steffen Gay Stephen L Nutt David W Boykin Gregory M K Poon Oliver Distler Georg Schett Jörg H W Distler Andreas Ramming

Nature 2019 02 30;566(7744):344-349. Epub 2019 Jan 30.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://www.nature.com/articles/s41586-019-0896-x
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http://dx.doi.org/10.1038/s41586-019-0896-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526281PMC
February 2019

ADSCs and adipocytes are the main producers in the autotaxin-lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro.

Authors:
Rafael Schmid Katharina Wolf Jan W Robering Selina Strauß Pamela L Strissel Reiner Strick Matthias Rübner Peter A Fasching Raymund E Horch Andreas E Kremer Anja M Boos Annika Weigand

BMC Cancer 2018 Dec 19;18(1):1273. Epub 2018 Dec 19.

Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Krankenhausstr. 12, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s12885-018-5166-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300006PMC
December 2018

Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles.

Authors:
Anita N Kremer Marijke I Zonneveld Andreas E Kremer Edith D van der Meijden J H Frederik Falkenburg Marca H M Wauben Esther N M Nolte-'t Hoen Marieke Griffioen

Eur J Immunol 2018 10 17;48(10):1621-1631. Epub 2018 Aug 17.

Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/eji.201747152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220790PMC
October 2018

Management of Chronic Hepatic Itch.

Authors:
Miriam M Düll Andreas E Kremer

Dermatol Clin 2018 Jul 1;36(3):293-300. Epub 2018 May 1.

Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, Erlangen 91054, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.det.2018.02.008DOI Listing
July 2018

Can genetic testing guide the therapy of cholestatic pruritus? A case of benign recurrent intrahepatic cholestasis type 2 with severe nasobiliary drainage-refractory itch.

Authors:
Robert Holz Andreas E Kremer Dieter Lütjohann Hermann E Wasmuth Frank Lammert Marcin Krawczyk

Hepatol Commun 2018 02 10;2(2):152-154. Epub 2018 Jan 10.

Department of Medicine II, Saarland University Medical Center Saarland University Homburg Germany.

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http://dx.doi.org/10.1002/hep4.1144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796322PMC
February 2018

Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study.

Authors:
David Jones Pol F Boudes Mark G Swain Christopher L Bowlus Michael R Galambos Bruce R Bacon Yvonne Doerffel Norman Gitlin Stuart C Gordon Joseph A Odin David Sheridan Markus-Alexander Wörns Virginia Clark Linsey Corless Heinz Hartmann Mark E Jonas Andreas E Kremer George F Mells Peter Buggisch Bradley L Freilich Cynthia Levy John M Vierling David E Bernstein Marek Hartleb Ewa Janczewska Fedja Rochling Hemant Shah Mitchell L Shiffman John H Smith Yun-Jung Choi Alexandra Steinberg Monika Varga Harinder Chera Robert Martin Charles A McWherter Gideon M Hirschfield

Lancet Gastroenterol Hepatol 2017 10 14;2(10):716-726. Epub 2017 Aug 14.

Center for Liver Research, Birmingham NIHR Biomedical Research Center, University of Birmingham, Birmingham, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S24681253173024
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http://dx.doi.org/10.1016/S2468-1253(17)30246-7DOI Listing
October 2017

S2k Guidelines for the diagnosis and treatment of chronic pruritus - update - short version.

Authors:
Sonja Ständer Claudia Zeidler Matthias Augustin Gudrun Bayer Andreas E Kremer Franz J Legat Peter Maisel Thomas Mettang Martin Metz Alexander Nast Volker Niemeier Ulrike Raap Gudrun Schneider Hartmut F Ständer Petra Staubach Markus Streit Elke Weisshaar

J Dtsch Dermatol Ges 2017 Aug;15(8):860-872

Department of Clinical Social Medicine, Occupational and Environmental Dermatology, University Medical Center, Heidelberg, Germany.

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http://dx.doi.org/10.1111/ddg.13304DOI Listing
August 2017

S2k-Leitlinie zur Diagnostik und Therapie des chronischen Pruritus - Update - Kurzversion.

Authors:
Sonja Ständer Claudia Zeidler Matthias Augustin Gudrun Bayer Andreas E Kremer Franz J Legat Peter Maisel Thomas Mettang Martin Metz Alexander Nast Volker Niemeier Ulrike Raap Gudrun Schneider Hartmut F Ständer Petra Staubach Markus Streit Elke Weisshaar

J Dtsch Dermatol Ges 2017 Aug;15(8):860-873

Klinische Sozialmedizin, Berufs und Umweltdermatologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.

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http://dx.doi.org/10.1111/ddg.13304_gDOI Listing
August 2017

PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury.

Authors:
Gui-Wei He Claudia Günther Andreas E Kremer Veronika Thonn Kerstin Amann Christopher Poremba Markus F Neurath Stefan Wirtz Christoph Becker

Gut 2017 04 26;66(4):716-723. Epub 2016 Aug 26.

Department of Medicine 1, Friedrich-Alexander-University, Erlangen, Germany.

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http://dx.doi.org/10.1136/gutjnl-2015-311247DOI Listing
April 2017

The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis.

Authors:
Claudia Günther Gui-Wei He Andreas E Kremer James M Murphy Emma J Petrie Kerstin Amann Peter Vandenabeele Andreas Linkermann Christopher Poremba Ulrike Schleicher Christin Dewitz Stefan Krautwald Markus F Neurath Christoph Becker Stefan Wirtz

J Clin Invest 2016 11 17;126(11):4346-4360. Epub 2016 Oct 17.

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http://dx.doi.org/10.1172/JCI87545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096909PMC
November 2016

Chronic Pruritus in the Absence of Skin Disease: Pathophysiology, Diagnosis and Treatment.

Authors:
Manuel P Pereira Andreas E Kremer Thomas Mettang Sonja Ständer

Am J Clin Dermatol 2016 Aug;17(4):337-48

Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Von-Esmarch-Str. 58, 48149, Münster, Germany.

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http://link.springer.com/content/pdf/10.2165/11317620-000000
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http://link.springer.com/10.1007/s40257-016-0198-0
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http://dx.doi.org/10.1007/s40257-016-0198-0DOI Listing
August 2016

Successful Multidisciplinary Treatment with Secondary Metastatic Liver Resection after Downsizing by Palliative Second-Line Treatment of Colorectal Cancer: A Curative Option.

Authors:
Axel Wein Jürgen Siebler Ruediger Goertz Kerstin Wolff Nicola Ostermeier Dagmar Busse Andreas E Kremer Franz Koch Alexander Hagel Michael Farnbacher Ferdinand J Kammerer Markus F Neurath Robert Gruetzmann

Case Rep Oncol 2016 May-Aug;9(2):379-86. Epub 2016 Jul 9.

Department of Surgery, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000445677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960360PMC
August 2016

Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases.

Authors:
Ewa Wunsch Marcin Krawczyk Malgorzata Milkiewicz Jocelyn Trottier Olivier Barbier Markus F Neurath Frank Lammert Andreas E Kremer Piotr Milkiewicz

Sci Rep 2016 08 10;6:30847. Epub 2016 Aug 10.

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.

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http://dx.doi.org/10.1038/srep30847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978954PMC
August 2016

Pathogenesis and Management of Pruritus in PBC and PSC.

Authors:
Andreas E Kremer Barbara Namer Ruth Bolier Michael J Fischer Ronald P Oude Elferink Ulrich Beuers

Dig Dis 2015 7;33 Suppl 2:164-75. Epub 2015 Dec 7.

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http://dx.doi.org/10.1159/000440829DOI Listing
July 2016

[Management of pruritus in patients with cholestatic liver disease].

Authors:
Andreas E Kremer M R Kraus

MMW Fortschr Med 2016 Jun;158(12):64-7

.

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http://dx.doi.org/10.1007/s15006-016-8449-9DOI Listing
June 2016

Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum.

Authors:
Shadi Abu-Hayyeh Caroline Ovadia TinaMarie Lieu Dane D Jensen Jenny Chambers Peter H Dixon Anita Lövgren-Sandblom Ruth Bolier Dagmar Tolenaars Andreas E Kremer Argyro Syngelaki Muna Noori David Williams Jose J G Marin Maria J Monte Kypros H Nicolaides Ulrich Beuers Ronald Oude-Elferink Paul T Seed Lucy Chappell Hanns-Ulrich Marschall Nigel W Bunnett Catherine Williamson

Hepatology 2016 Apr 28;63(4):1287-98. Epub 2015 Dec 28.

Women's Health Academic Centre, King's College London, London, United Kingdom.

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http://doi.wiley.com/10.1002/hep.28265
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http://dx.doi.org/10.1002/hep.28265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869673PMC
April 2016

Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders.

Authors:
Andreas E Kremer Emmanuel Gonzales Frank G Schaap Ronald P J Oude Elferink Emmanuel Jacquemin Ulrich Beuers

J Pediatr Gastroenterol Nutr 2016 Apr;62(4):530-5

*Department of Medicine I, Friedrich-Alexander-University of Erlangen, Erlangen, Germany †Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands ‡Pediatric Hepatology Unit and National Reference Centre for Biliary Atresia, DHU Hepatinov, CHU Bicêtre, Assistance Publique-Hôpitaux de Paris, University Paris-Sud, Paris, and Inserm UMR-S1174, Orsay, France §Department of Surgery, University of Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/MPG.0000000000001044DOI Listing
April 2016

Enteroendocrine cells are a potential source of serum autotaxin in men.

Authors:
Ruth Bolier Dagmar Tolenaars Andreas E Kremer Job Saris Albert Parés Joanne Verheij Piter J Bosma Ulrich Beuers Ronald P J Oude Elferink

Biochim Biophys Acta 2016 04 14;1862(4):696-704. Epub 2016 Jan 14.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.01.012DOI Listing
April 2016

Advances in hepatitis C therapy: What is the current state - what come's next?

Authors:
Steffen Zopf Andreas E Kremer Markus F Neurath Juergen Siebler

World J Hepatol 2016 Jan;8(3):139-47

Steffen Zopf, Andreas E Kremer, Markus F Neurath, Juergen Siebler, Medical Department 1, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.4254/wjh.v8.i3.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724577PMC
January 2016

Impact of global Fxr deficiency on experimental acute pancreatitis and genetic variation in the FXR locus in human acute pancreatitis.

Authors:
Rian M Nijmeijer Frank G Schaap Alexander J J Smits Andreas E Kremer Louis M A Akkermans Alfons B A Kroese Ger T Rijkers Marguerite E I Schipper André Verheem Cisca Wijmenga Hein G Gooszen Karel J van Erpecum

PLoS One 2014 3;9(12):e114393. Epub 2014 Dec 3.

Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114393PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255038PMC
December 2015

Reply: To PMID 24807046.

Authors:
Ronald Oude Elferink Ruth Bolier Andreas E Kremer Ulrich Beuers

Hepatology 2015 Jun 18;61(6):2115. Epub 2015 Apr 18.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.27579DOI Listing
June 2015

Uremic pruritus.

Authors:
Thomas Mettang Andreas E Kremer

Kidney Int 2015 Apr 8;87(4):685-91. Epub 2014 Jan 8.

Department of Medicine 1, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/ki.2013.454DOI Listing
April 2015

Characterization and treatment of persistent hepatocellular secretory failure.

Authors:
Remco van Dijk Andreas E Kremer Wouter Smit Bram van den Elzen Thomas van Gulik Dirk Gouma Johan S Lameris Hennie Bikker Valentine Enemuo Pieter C F Stokkers Mark Feist Piter Bosma Peter L M Jansen Ulrich Beuers

Liver Int 2015 Apr 4;35(4):1478-88. Epub 2014 Jul 4.

Department of Gastroenterology & Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/liv.12603DOI Listing
April 2015

Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy.

Authors:
Andreas E Kremer Ruth Bolier Peter H Dixon Victoria Geenes Jenny Chambers Dagmar Tolenaars Carrie Ris-Stalpers Bernhard M Kaess Christian Rust Joris A van der Post Catherine Williamson Ulrich Beuers Ronald P J Oude Elferink

J Hepatol 2015 Apr 5;62(4):897-904. Epub 2014 Nov 5.

Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.10.041DOI Listing
April 2015

Advances in pathogenesis and management of pruritus in cholestasis.

Authors:
Andreas E Kremer Ruth Bolier Remco van Dijk Ronald P J Oude Elferink Ulrich Beuers

Dig Dis 2014 14;32(5):637-45. Epub 2014 Jul 14.

Department of Medicine 1, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000360518DOI Listing
March 2015

Clinical management of pruritus.

Authors:
Sonja Ständer Claudia Zeidler Nina Magnolo Ulrike Raap Thomas Mettang Andreas E Kremer Elke Weisshaar Matthias Augustin

J Dtsch Dermatol Ges 2015 Feb;13(2):101-15; quiz 116

Competence Center Chronic Pruritus, Department of Dermatology, University Hospital Muenster, Germany.

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http://dx.doi.org/10.1111/ddg.12522DOI Listing
February 2015

Total bile acids in the maternal and fetal compartment in relation to placental ABCG2 expression in preeclamptic pregnancies complicated by HELLP syndrome.

Authors:
Jiska Jebbink Geertruda Veenboer Souad Boussata Remco Keijser Andreas E Kremer Ronald Oude Elferink Joris van der Post Gijs Afink Carrie Ris-Stalpers

Biochim Biophys Acta 2015 Jan 12;1852(1):131-6. Epub 2014 Nov 12.

Women's and Children's Clinic, Academic Medical Center, University of Amsterdam, PO Box 22660, Amsterdam 1100 DD, The Netherlands; Reproductive Biology Laboratory, Academic Medical Center, University of Amsterdam, PO Box 22660, Amsterdam 1100 DD, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2014.11.008DOI Listing
January 2015

Receptors, cells and circuits involved in pruritus of systemic disorders.

Authors:
Andreas E Kremer Jamison Feramisco Peter W Reeh Ulrich Beuers Ronald P J Oude Elferink

Biochim Biophys Acta 2014 Jul 22;1842(7):869-92. Epub 2014 Feb 22.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2014.02.007DOI Listing
July 2014

Pruritus in cholestasis: facts and fiction.

Authors:
Ulrich Beuers Andreas E Kremer Ruth Bolier Ronald P J Oude Elferink

Hepatology 2014 Jul 29;60(1):399-407. Epub 2014 May 29.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.26909DOI Listing
July 2014

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress.

Authors:
Frank G Schaap Andreas E Kremer Wouter H Lamers Peter L M Jansen Ingrid C Gaemers

Biochimie 2013 Apr 2;95(4):692-9. Epub 2012 Nov 2.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Meibergdreef 69-71, 1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biochi.2012.10.019DOI Listing
April 2013

Cholestatic pruritus: a retrospective analysis on clinical characteristics and treatment response.

Authors:
Mario Huesmann Timo Huesmann Nani Osada Ngoc Quan Phan Andreas E Kremer Sonja Ständer

J Dtsch Dermatol Ges 2013 Feb 29;11(2):158-68. Epub 2012 Nov 29.

Competence Center Chronic Pruritus and Department of Dermatology, University Hospital Münster, Germany.

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http://dx.doi.org/10.1111/j.1610-0387.2012.08028.xDOI Listing
February 2013

Serum autotaxin is increased in pruritus of cholestasis, but not of other origin, and responds to therapeutic interventions.

Authors:
Andreas E Kremer Remco van Dijk Pamela Leckie Frank G Schaap Edith M M Kuiper Thomas Mettang Katrin S Reiners Ulrike Raap Henk R van Buuren Karel J van Erpecum Nathan A Davies Christian Rust Andreas Engert Rajiv Jalan Ronald P J Oude Elferink Ulrich Beuers

Hepatology 2012 Oct;56(4):1391-400

Tytgat Institute for Liver and Intestinal Research, Department of gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.25748DOI Listing
October 2012

Increased frequencies of IL-31-producing T cells are found in chronic atopic dermatitis skin.

Authors:
Krisztina Szegedi Andreas E Kremer Sanja Kezic Marcel B M Teunissen Jan D Bos Rosalie M Luiten Pieter C Res Maritza A Middelkamp-Hup

Exp Dermatol 2012 Jun;21(6):431-6

Department of Dermatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1600-0625.2012.01487.xDOI Listing
June 2012

Brushing of bile duct stenoses for the true dignity.

Authors:
Andreas E Kremer Ulrich Beuers

Liver Int 2012 May;32(5):698-700

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http://dx.doi.org/10.1111/j.1478-3231.2012.02789.xDOI Listing
May 2012

[Pruritus in liver disease. Pathogenesis and treatment].

Authors:
Andreas E Kremer Lucas Maillette de Buy Wenniger Ronald P J Oude Elferink Ulrich Beuers

Ned Tijdschr Geneeskd 2011 ;155(52):A4045

Tytgat Instituut voor Lever- en Gastrointestinaal Onderzoek en afd. Maag-, Darm-, Leverziekten, Academisch Medisch Centrum, Amsterdam, the Netherlands.

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February 2012

The molecular mechanism of cholestatic pruritus.

Authors:
Ronald P J Oude Elferink Andreas E Kremer Job J W W Martens Ulrich H Beuers

Dig Dis 2011 17;29(1):66-71. Epub 2011 Jun 17.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000324131DOI Listing
October 2011

The molecular mechanism of cholestatic pruritus.

Authors:
Ronald P J Oude Elferink Andreas E Kremer Job J W W Martens Ulrich H Beuers

Dig Dis 2011 17;29(1):66-71. Epub 2011 Jun 17.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000324131DOI Listing
October 2011

Pathophysiology and current management of pruritus in liver disease.

Authors:
Andreas E Kremer Ronald P J Oude Elferink Ulrich Beuers

Clin Res Hepatol Gastroenterol 2011 Feb;35(2):89-97

Tytgat Institute for liver and intestinal research, Department of gastroenterology and hepatology, Academic Medical Center, S1-164, University of Amsterdam, Meibergdreef 69-71, NL-1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.clinre.2010.10.007DOI Listing
February 2011

The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies.

Authors:
Ulrich Beuers Simon Hohenester Lucas J Maillette de Buy Wenniger Andreas E Kremer Peter L M Jansen Ronald P J Oude Elferink

Hepatology 2010 Oct;52(4):1489-96

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.23810DOI Listing
October 2010

Lysophosphatidic acid is a potential mediator of cholestatic pruritus.

Authors:
Andreas E Kremer Job J W W Martens Wim Kulik Franziska Ruëff Edith M M Kuiper Henk R van Buuren Karel J van Erpecum Jurate Kondrackiene Jesus Prieto Christian Rust Victoria L Geenes Catherine Williamson Wouter H Moolenaar Ulrich Beuers Ronald P J Oude Elferink

Gastroenterology 2010 Sep 19;139(3):1008-18, 1018.e1. Epub 2010 Jun 19.

Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2010.05.009DOI Listing
September 2010

Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers.

Authors:
Andreas E Kremer Christian Rust Peter Eichhorn Ulrich Beuers Stefan Holdenrieder

Expert Rev Mol Diagn 2009 Mar;9(2):139-56

AMC Liver Center, S1-164, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.

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http://www.tandfonline.com/doi/full/10.1586/14737159.9.2.139
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http://dx.doi.org/10.1586/14737159.9.2.139DOI Listing
March 2009

Pathogenesis and treatment of pruritus in cholestasis.

Authors:
Andreas E Kremer Ulrich Beuers Ronald P J Oude-Elferink Thomas Pusl

Drugs 2008 ;68(15):2163-82

Liver Center, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.2165/00003495-200868150-00006DOI Listing
January 2009

Clinical relevance of circulating nucleosomes in cancer.

Authors:
Stefan Holdenrieder Dorothea Nagel Andreas Schalhorn Volker Heinemann Ralf Wilkowski Joachim von Pawel Hannelore Raith Knut Feldmann Andreas E Kremer Susanne Müller Sandra Geiger Gerhard F Hamann Dietrich Seidel Petra Stieber

Ann N Y Acad Sci 2008 Aug;1137:180-9

Institute of Clinical Chemistry, University Hospital of Munich, Munich, Germany.

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http://doi.wiley.com/10.1196/annals.1448.012
Publisher Site
http://dx.doi.org/10.1196/annals.1448.012DOI Listing
August 2008