Andreas E Kremer

Andreas E Kremer

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Andreas E Kremer

Andreas E Kremer

Publications by authors named "Andreas E Kremer"

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54Publications

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Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure.

Cell Death Dis 2019 Nov 21;10(12):878. Epub 2019 Nov 21.

Department of Medicine 1, University hospital, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41419-019-2115-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872756PMC
November 2019

Antipruritic effect of bezafibrate and serum autotaxin measures in patients with primary biliary cholangitis.

Gut 2019 10 18;68(10):1902-1903. Epub 2018 Sep 18.

Reference Center for Inflammatory Biliary Diseases and Autoimmune Hepatitis, Saint-Antoine Hospital, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France.

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http://dx.doi.org/10.1136/gutjnl-2018-317426DOI Listing
October 2019

What are new treatment concepts in systemic itch?

Authors:
Andreas E Kremer

Exp Dermatol 2019 Aug 27. Epub 2019 Aug 27.

Department of Medicine 1 & Translational Research Center, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/exd.14024DOI Listing
August 2019

Peripheral Sensitization and Loss of Descending Inhibition Is a Hallmark of Chronic Pruritus.

J Invest Dermatol 2019 Jul 2. Epub 2019 Jul 2.

Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, North Rhine-Westphalia, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.05.029DOI Listing
July 2019

Treatment of Pruritus Secondary to Liver Disease.

Curr Gastroenterol Rep 2019 Jul 31;21(9):48. Epub 2019 Jul 31.

Department of Medicine 1, Gastroenterology, Hepatology, Pneumology and Endocrinology, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, D-91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s11894-019-0713-6DOI Listing
July 2019

A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats.

Cell Mol Gastroenterol Hepatol 2019 23;7(3):571-596. Epub 2018 Dec 23.

Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Toxicology and Environmental Hygiene, Technical University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407159PMC
June 2019

Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis.

Sci Rep 2019 Jun 11;9(1):8450. Epub 2019 Jun 11.

Norwegian PSC Research Center, Department of transplantation medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1038/s41598-019-44762-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559994PMC
June 2019

Lysophosphatidic acid activates satellite glia cells and Schwann cells.

Glia 2019 05 13;67(5):999-1012. Epub 2019 Jan 13.

Institute of Physiology and Pathophysiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/glia.23585DOI Listing
May 2019

ADSCs and adipocytes are the main producers in the autotaxin-lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro.

BMC Cancer 2018 Dec 19;18(1):1273. Epub 2018 Dec 19.

Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Krankenhausstr. 12, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s12885-018-5166-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300006PMC
December 2018

Management of Chronic Hepatic Itch.

Dermatol Clin 2018 Jul 1;36(3):293-300. Epub 2018 May 1.

Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, Erlangen 91054, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.det.2018.02.008DOI Listing
July 2018

S2k Guidelines for the diagnosis and treatment of chronic pruritus - update - short version.

J Dtsch Dermatol Ges 2017 Aug;15(8):860-872

Department of Clinical Social Medicine, Occupational and Environmental Dermatology, University Medical Center, Heidelberg, Germany.

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http://dx.doi.org/10.1111/ddg.13304DOI Listing
August 2017

PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury.

Gut 2017 04 26;66(4):716-723. Epub 2016 Aug 26.

Department of Medicine 1, Friedrich-Alexander-University, Erlangen, Germany.

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http://dx.doi.org/10.1136/gutjnl-2015-311247DOI Listing
April 2017

Chronic Pruritus in the Absence of Skin Disease: Pathophysiology, Diagnosis and Treatment.

Am J Clin Dermatol 2016 Aug;17(4):337-48

Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Von-Esmarch-Str. 58, 48149, Münster, Germany.

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http://link.springer.com/content/pdf/10.2165/11317620-000000
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http://link.springer.com/10.1007/s40257-016-0198-0
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http://dx.doi.org/10.1007/s40257-016-0198-0DOI Listing
August 2016

Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases.

Sci Rep 2016 08 10;6:30847. Epub 2016 Aug 10.

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.

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http://dx.doi.org/10.1038/srep30847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978954PMC
August 2016

[Management of pruritus in patients with cholestatic liver disease].

MMW Fortschr Med 2016 Jun;158(12):64-7

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http://dx.doi.org/10.1007/s15006-016-8449-9DOI Listing
June 2016

Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders.

J Pediatr Gastroenterol Nutr 2016 Apr;62(4):530-5

*Department of Medicine I, Friedrich-Alexander-University of Erlangen, Erlangen, Germany †Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands ‡Pediatric Hepatology Unit and National Reference Centre for Biliary Atresia, DHU Hepatinov, CHU Bicêtre, Assistance Publique-Hôpitaux de Paris, University Paris-Sud, Paris, and Inserm UMR-S1174, Orsay, France §Department of Surgery, University of Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/MPG.0000000000001044DOI Listing
April 2016

Enteroendocrine cells are a potential source of serum autotaxin in men.

Biochim Biophys Acta 2016 04 14;1862(4):696-704. Epub 2016 Jan 14.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.01.012DOI Listing
April 2016

Advances in hepatitis C therapy: What is the current state - what come's next?

World J Hepatol 2016 Jan;8(3):139-47

Steffen Zopf, Andreas E Kremer, Markus F Neurath, Juergen Siebler, Medical Department 1, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.4254/wjh.v8.i3.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724577PMC
January 2016

Reply: To PMID 24807046.

Hepatology 2015 Jun 18;61(6):2115. Epub 2015 Apr 18.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.27579DOI Listing
June 2015

Uremic pruritus.

Kidney Int 2015 Apr 8;87(4):685-91. Epub 2014 Jan 8.

Department of Medicine 1, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/ki.2013.454DOI Listing
April 2015

Characterization and treatment of persistent hepatocellular secretory failure.

Liver Int 2015 Apr 4;35(4):1478-88. Epub 2014 Jul 4.

Department of Gastroenterology & Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/liv.12603DOI Listing
April 2015

Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy.

J Hepatol 2015 Apr 5;62(4):897-904. Epub 2014 Nov 5.

Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.10.041DOI Listing
April 2015

Advances in pathogenesis and management of pruritus in cholestasis.

Dig Dis 2014 14;32(5):637-45. Epub 2014 Jul 14.

Department of Medicine 1, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000360518DOI Listing
March 2015

Clinical management of pruritus.

J Dtsch Dermatol Ges 2015 Feb;13(2):101-15; quiz 116

Competence Center Chronic Pruritus, Department of Dermatology, University Hospital Muenster, Germany.

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http://dx.doi.org/10.1111/ddg.12522DOI Listing
February 2015

Total bile acids in the maternal and fetal compartment in relation to placental ABCG2 expression in preeclamptic pregnancies complicated by HELLP syndrome.

Biochim Biophys Acta 2015 Jan 12;1852(1):131-6. Epub 2014 Nov 12.

Women's and Children's Clinic, Academic Medical Center, University of Amsterdam, PO Box 22660, Amsterdam 1100 DD, The Netherlands; Reproductive Biology Laboratory, Academic Medical Center, University of Amsterdam, PO Box 22660, Amsterdam 1100 DD, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2014.11.008DOI Listing
January 2015

Receptors, cells and circuits involved in pruritus of systemic disorders.

Biochim Biophys Acta 2014 Jul 22;1842(7):869-92. Epub 2014 Feb 22.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2014.02.007DOI Listing
July 2014

Pruritus in cholestasis: facts and fiction.

Hepatology 2014 Jul 29;60(1):399-407. Epub 2014 May 29.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.26909DOI Listing
July 2014

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress.

Biochimie 2013 Apr 2;95(4):692-9. Epub 2012 Nov 2.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Meibergdreef 69-71, 1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biochi.2012.10.019DOI Listing
April 2013

Cholestatic pruritus: a retrospective analysis on clinical characteristics and treatment response.

J Dtsch Dermatol Ges 2013 Feb 29;11(2):158-68. Epub 2012 Nov 29.

Competence Center Chronic Pruritus and Department of Dermatology, University Hospital Münster, Germany.

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http://dx.doi.org/10.1111/j.1610-0387.2012.08028.xDOI Listing
February 2013

Serum autotaxin is increased in pruritus of cholestasis, but not of other origin, and responds to therapeutic interventions.

Hepatology 2012 Oct;56(4):1391-400

Tytgat Institute for Liver and Intestinal Research, Department of gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.25748DOI Listing
October 2012

Increased frequencies of IL-31-producing T cells are found in chronic atopic dermatitis skin.

Exp Dermatol 2012 Jun;21(6):431-6

Department of Dermatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1600-0625.2012.01487.xDOI Listing
June 2012

Brushing of bile duct stenoses for the true dignity.

Liver Int 2012 May;32(5):698-700

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http://dx.doi.org/10.1111/j.1478-3231.2012.02789.xDOI Listing
May 2012

[Pruritus in liver disease. Pathogenesis and treatment].

Ned Tijdschr Geneeskd 2011 ;155(52):A4045

Tytgat Instituut voor Lever- en Gastrointestinaal Onderzoek en afd. Maag-, Darm-, Leverziekten, Academisch Medisch Centrum, Amsterdam, the Netherlands.

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February 2012

The molecular mechanism of cholestatic pruritus.

Dig Dis 2011 17;29(1):66-71. Epub 2011 Jun 17.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000324131DOI Listing
October 2011

The molecular mechanism of cholestatic pruritus.

Dig Dis 2011 17;29(1):66-71. Epub 2011 Jun 17.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000324131DOI Listing
October 2011

Pathophysiology and current management of pruritus in liver disease.

Clin Res Hepatol Gastroenterol 2011 Feb;35(2):89-97

Tytgat Institute for liver and intestinal research, Department of gastroenterology and hepatology, Academic Medical Center, S1-164, University of Amsterdam, Meibergdreef 69-71, NL-1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.clinre.2010.10.007DOI Listing
February 2011

The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies.

Hepatology 2010 Oct;52(4):1489-96

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.23810DOI Listing
October 2010

Lysophosphatidic acid is a potential mediator of cholestatic pruritus.

Gastroenterology 2010 Sep 19;139(3):1008-18, 1018.e1. Epub 2010 Jun 19.

Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2010.05.009DOI Listing
September 2010

Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers.

Expert Rev Mol Diagn 2009 Mar;9(2):139-56

AMC Liver Center, S1-164, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.

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http://www.tandfonline.com/doi/full/10.1586/14737159.9.2.139
Publisher Site
http://dx.doi.org/10.1586/14737159.9.2.139DOI Listing
March 2009

Pathogenesis and treatment of pruritus in cholestasis.

Drugs 2008 ;68(15):2163-82

Liver Center, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.2165/00003495-200868150-00006DOI Listing
January 2009