Publications by authors named "Andrea Velardi"

94Publications

CD4FOXP3 Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation.

Front Immunol 2019 17;10:2901. Epub 2019 Dec 17.

Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
November 2020

The Evolution of T Cell Depleted Haploidentical Transplantation.

Front Immunol 2019 27;10:2769. Epub 2019 Nov 27.

Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
November 2020

The "ultimate" haploidentical transplantation for the elderly with high-risk acute myeloid leukemia.

Bone Marrow Transplant 2019 08;54(Suppl 2):803-805

Hematopoietic Stem Cell Transplantation Program, Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
August 2019

T cell depletion and no post transplant immune suppression allow separation of graft versus leukemia from graft versus host disease.

Bone Marrow Transplant 2019 08;54(Suppl 2):775-779

Blood and Marrow Transplantation Program, Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
August 2019

TNFR2 signaling modulates immunity after allogeneic hematopoietic cell transplantation.

Cytokine Growth Factor Rev 2019 06 15;47:54-61. Epub 2019 May 15.

Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, Perugia, 06132, Italy. Electronic address:

View Article and Find Full Text PDF
June 2019

The Effect of TNF-α on Regulatory T Cell Function in Graft-versus-Host Disease.

Front Immunol 2018 28;9:356. Epub 2018 Feb 28.

Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
April 2019

Clinical-Grade-Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell-Dependent Graft-versus-Leukemia Effect in Murine Models.

Biol Blood Marrow Transplant 2017 Nov 17;23(11):1847-1851. Epub 2017 Jul 17.

Department of Hematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy; Department of Medicine and Aging Sciences, University of Chieti-Pescara, Italy. Electronic address:

View Article and Find Full Text PDF
November 2017

Foxp3 regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis.

Nat Commun 2017 05 9;8:15068. Epub 2017 May 9.

Department of Medicine, Division of Blood and Marrow Transplantation, Stanford University, 269W. Campus Drive, Stanford, California 94305, USA.

View Article and Find Full Text PDF
May 2017

The Total Body Irradiation Schedule Affects Acute Leukemia Relapse After Matched T Cell-Depleted Hematopoietic Stem Cell Transplantation.

Int J Radiat Oncol Biol Phys 2016 11 27;96(4):832-839. Epub 2016 Jul 27.

Division of Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, Perugia General Hospital and University, Perugia, Italy.

View Article and Find Full Text PDF
November 2016

Haploidentical hematopoietic transplantation for the cure of leukemia: from its biology to clinical translation.

Blood 2016 12 3;128(23):2616-2623. Epub 2016 Oct 3.

Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
December 2016

Identifying NK Alloreactive Donors for Haploidentical Hematopoietic Stem Cell Transplantation.

Methods Mol Biol 2016 ;1393:141-5

Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
December 2016

New mechanism of lymphoma-induced bone marrow aplasia.

Ann Hematol 2016 May 9;95(6):1013-5. Epub 2016 Mar 9.

Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
May 2016

Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells.

Haematologica 2016 05 31;101(5):626-33. Epub 2015 Dec 31.

Division of Hematology and Clinical Immunology and Bone Marrow Transplantation Program, Department of Medicine, University of Perugia, Italy.

View Article and Find Full Text PDF
May 2016

Haploidentical hematopoietic stem cell transplantation: step-by-step progress.

Authors:
Andrea Velardi

Biol Blood Marrow Transplant 2015 Apr 11;21(4):579-80. Epub 2015 Feb 11.

Blood and Marrow Transplant Program, Division of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy. Electronic address:

View Article and Find Full Text PDF
April 2015

The cross-talk between opportunistic fungi and the mammalian host via microbiota's metabolism.

Semin Immunopathol 2015 Mar 18;37(2):163-71. Epub 2014 Nov 18.

Department of Experimental Medicine, University of Perugia, Polo Unico Sant'Andrea delle Fratte, 06132, Perugia, Italy,

View Article and Find Full Text PDF
March 2015

HLA-C expression levels define permissible mismatches in hematopoietic cell transplantation.

Blood 2014 Dec 16;124(26):3996-4003. Epub 2014 Oct 16.

Cancer and Inflammation Program, SAIC Frederick, Inc., Frederick National Laboratories for Cancer Research, Frederick, MD; and Ragon Institute of the Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA.

View Article and Find Full Text PDF
December 2014

"Designed" grafts for HLA-haploidentical stem cell transplantation.

Blood 2014 Feb 20;123(7):967-73. Epub 2013 Dec 20.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy;

View Article and Find Full Text PDF
February 2014

Haplo-BMT: which approach?

Authors:
Andrea Velardi

Blood 2013 Jan;121(5):719-20

University of Perugia.

View Article and Find Full Text PDF
January 2013

Jack of all trades: thymosin α1 and its pleiotropy.

Ann N Y Acad Sci 2012 Oct;1269:1-6

Department of Experimental Medicine and Biochemical Science, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
October 2012

Natural killer cell alloreactivity 10 years later.

Authors:
Andrea Velardi

Curr Opin Hematol 2012 Nov;19(6):421-6

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
November 2012

An overview of methods required to evaluate donor NK cell alloreactivity for haploidentical haemopoietic stem cell transplantation.

Authors:
Andrea Velardi

Methods Mol Biol 2012 ;882:469-76

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, Perugia, Italy.

View Article and Find Full Text PDF
October 2012

Killer-cell immunoglobulin-like receptors reactivity and outcome of stem cell transplant.

Curr Opin Hematol 2012 Jul;19(4):319-23

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
July 2012

Natural revenge over cytomegalovirus.

Authors:
Andrea Velardi

Blood 2012 Mar;119(11):2438-9

University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
March 2012

Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study.

Lancet Oncol 2012 Apr 15;13(4):366-74. Epub 2012 Feb 15.

Unit of Molecular and Functional Immunogenetics, Division of Regenerative Medicine, Stem Cells and Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, Milan, Italy.

View Article and Find Full Text PDF
April 2012

Expansion of CD56-negative, CD16-positive, KIR-expressing natural killer cells after T cell-depleted haploidentical hematopoietic stem cell transplantation.

Acta Haematol 2011 17;126(1):13-20. Epub 2011 Mar 17.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
August 2011

Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: a tool for immunotherapy of leukemia.

Curr Opin Immunol 2009 Oct 28;21(5):525-30. Epub 2009 Aug 28.

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, 06132 - Perugia, Italy.

View Article and Find Full Text PDF
October 2009

Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation.

Semin Immunopathol 2008 Dec 11;30(4):489-503. Epub 2008 Nov 11.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, Perugia, Italy.

View Article and Find Full Text PDF
December 2008

Role of KIRs and KIR ligands in hematopoietic transplantation.

Authors:
Andrea Velardi

Curr Opin Immunol 2008 Oct 23;20(5):581-7. Epub 2008 Aug 23.

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, 06129 Perugia, Italy.

View Article and Find Full Text PDF
October 2008

Human leukocyte antigens A23, A24, and A32 but not A25 are ligands for KIR3DL1.

Blood 2008 Aug 23;112(3):708-10. Epub 2008 May 23.

Department of Hematology, University Hospital Basel, Basel, Switzerland.

View Article and Find Full Text PDF
August 2008

Hematopoietic stem cell transplantation from alternative donors for high-risk acute leukemia: the haploidentical option.

Curr Stem Cell Res Ther 2007 Jan;2(1):105-12

Hematopoietic Stem Cell Transplant Unit, Section of Hematology and Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia 06100, Italy.

View Article and Find Full Text PDF
January 2007

Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):76-83. Epub 2007 Nov 5.

Department of Clinical and Experimental Medicine, IRCCS Foundation on Transplantation Biotechnologies, University of Perugia, Via Brunamonti 51, 06123, Italy.

View Article and Find Full Text PDF
February 2008

NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):84-90. Epub 2007 Oct 26.

Department of Clinical and Experimental Medicine, IRCCS Foundation on Transplantation Biotechnologies, University of Perugia, Italy.

View Article and Find Full Text PDF
February 2008

Microparticles derived from endothelial progenitor cells in patients at different cardiovascular risk.

Atherosclerosis 2008 Apr 27;197(2):757-67. Epub 2007 Aug 27.

Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
April 2008

Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.

Blood 2007 Jul 19;110(1):433-40. Epub 2007 Mar 19.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Istituto di Ricovero e Cura a Carattere Scientifico, Foundation on Transplantation Biotechnologies, Perugia, Italy.

View Article and Find Full Text PDF
July 2007

Natural killer cell alloreactivity in allogeneic hematopoietic transplantation.

Curr Opin Oncol 2007 Mar;19(2):142-7

Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
March 2007

Allogeneic hematopoietic transplantation and natural killer cell recognition of missing self.

Immunol Rev 2006 Dec;214:202-18

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

View Article and Find Full Text PDF
December 2006

Natural killer cell recognition of missing self and haploidentical hematopoietic transplantation.

Semin Cancer Biol 2006 Oct 8;16(5):404-11. Epub 2006 Jul 8.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 51, Perugia, Italy.

View Article and Find Full Text PDF
October 2006

Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation.

Blood 2005 Dec 25;106(13):4397-406. Epub 2005 Aug 25.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 51-06122 Perugia, Italy.

View Article and Find Full Text PDF
December 2005

The impact of donor natural killer cell alloreactivity on allogeneic hematopoietic transplantation.

Transpl Immunol 2005 Aug;14(3-4):203-6

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

View Article and Find Full Text PDF
August 2005

Natural killer cell alloreactivity for leukemia therapy.

J Immunother 2005 May-Jun;28(3):175-82

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, 06122 Perugia, Italy.

View Article and Find Full Text PDF
October 2005

Exploitation of alloreactive NK cells in adoptive immunotherapy of cancer.

Curr Opin Immunol 2005 Apr;17(2):211-7

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, 06122 Perugia, Italy.

View Article and Find Full Text PDF
April 2005

Natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation.

Int J Hematol 2005 Jan;81(1):13-7

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
January 2005

Prospects for dendritic cell vaccination against fungal infections in hematopoietic transplantation.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):248-55

Division of Hematology, Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF
April 2005

Alloreactive natural killer cells in mismatched hematopoietic stem cell transplantation.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):216-21

Department of Clinical and Experimental Medicine, Haematology and Clinical Immunology, University of Perugia, Italy.

View Article and Find Full Text PDF
April 2005

Natural killer cells as a therapeutic tool in mismatched transplantation.

Best Pract Res Clin Haematol 2004 Sep;17(3):427-38

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 06100, Perugia, Italy.

View Article and Find Full Text PDF
September 2004

Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling.

Blood 2004 Jun 24;103(11):4232-9. Epub 2004 Feb 24.

Department of Experimental Medicine and Biochemical Sciences Microbiology Section, University of Perugia, Via del Giochetto, 06122 Perugia, Italy.

View Article and Find Full Text PDF
June 2004

A dendritic cell vaccine against invasive aspergillosis in allogeneic hematopoietic transplantation.

Blood 2003 Nov 5;102(10):3807-14. Epub 2003 Jun 5.

Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Via del Giochetto, 06122 Perugia, Italy.

View Article and Find Full Text PDF
November 2003

Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect.

Blood 2002 Sep;100(6):1935-47

Department of Internal Medicine, Division of Hematology/Oncology, The Ohio State University, A433A Starling Loving Hall, 320 W Tenth Avenue, Columbus, OH 43210, USA.

View Article and Find Full Text PDF
September 2002

NK cells: a lesson from mismatched hematopoietic transplantation.

Trends Immunol 2002 Sep;23(9):438-44

Dipartimento di Medicina Clinica e Sperimentale, Sezione di Ematologia e Immunologia Clinica, Università degli Studi di Perugia, Italy.

View Article and Find Full Text PDF
September 2002

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants.

Science 2002 Mar;295(5562):2097-100

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, Perugia University School of Medicine, Perugia, Italy.

View Article and Find Full Text PDF
March 2002