Publications by authors named "Andrea Sacconi"

61Publications

YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer.

Cancer Lett 2021 Mar 6;500:51-63. Epub 2020 Dec 6.

UOSD Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy. Electronic address:

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March 2021

Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer.

Commun Biol 2020 Nov 13;3(1):677. Epub 2020 Nov 13.

Preclinical Models and New Therapeutic Agents Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.

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November 2020

Effects of a Small Increase in Carbon Dioxide Pressure during Fermentation on Wine Aroma.

Foods 2020 Oct 19;9(10). Epub 2020 Oct 19.

Dipartimento di Scienze e Tecnologie Agrarie, Alimentari, Ambientali e Forestali, Università degli Studi di Firenze, Piazzale delle Cascine 16, 50144 Firenze, Italy.

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October 2020

Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entry.

Cancers (Basel) 2020 Aug 24;12(9). Epub 2020 Aug 24.

Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Unit of Histology and Medical Embryology, SAPIENZA University of Rome, 16 Via A. Scarpa, 00161 Roma, Italy.

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August 2020

Non-coding RNAs as Putative Biomarkers of Cancer-Associated Cachexia.

Front Cell Dev Biol 2020 21;8:257. Epub 2020 Apr 21.

Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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April 2020

Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages.

Cells 2020 02 11;9(2). Epub 2020 Feb 11.

IRCCS Regina Elena National Cancer Institute, Oncogenomic and Epigenetic Unit, Via E. Chianesi, 53, 00144 Rome, Italy.

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February 2020

The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas.

Cancers (Basel) 2019 09 11;11(9). Epub 2019 Sep 11.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

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September 2019

Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma.

J Exp Clin Cancer Res 2019 Aug 9;38(1):349. Epub 2019 Aug 9.

Oncogenomic and Epigenetic Unit, Department of Research, Diagnosis and Innovative Technologies, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi, 53, 00144, Rome, Italy.

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August 2019

β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer.

Nat Commun 2019 07 19;10(1):3196. Epub 2019 Jul 19.

Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, 00144, Rome, Italy.

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July 2019

Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer disease.

Semin Cell Dev Biol 2020 02 23;98:105-117. Epub 2019 May 23.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome, 00144, Italy. Electronic address:

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February 2020

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells.

Cell Death Dis 2019 01 8;10(1):17. Epub 2019 Jan 8.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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January 2019

Serum miR-22 as potential non-invasive predictor of poor clinical outcome in newly diagnosed, uniformly treated patients with diffuse large B-cell lymphoma: an explorative pilot study.

J Exp Clin Cancer Res 2018 May 2;37(1):95. Epub 2018 May 2.

Department of Research, Advanced Diagnostics and Technological Innovation, Genomic and Epigenetic Unit, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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May 2018

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.

Theranostics 2018 12;8(7):1850-1868. Epub 2018 Feb 12.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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February 2019

hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process.

Proc Natl Acad Sci U S A 2018 03 8;115(12):3132-3137. Epub 2018 Feb 8.

Unit of Preclinical Models and New Therapeutic Agents, IRCCS, Regina Elena National Cancer Institute, 00144 Rome, Italy;

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March 2018

In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells.

J Exp Clin Cancer Res 2017 06 6;36(1):76. Epub 2017 Jun 6.

Laboratory of Clinical Pathology and Medical Genetics, Foundation IRCCS Neurological Institute C. Besta, Via Celoria, 11, 20133, Milan, Italy.

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June 2017

MicroRNA-driven deregulation of cytokine expression helps development of drug resistance in metastatic melanoma.

Cytokine Growth Factor Rev 2017 08 17;36:39-48. Epub 2017 May 17.

Regina Elena National Cancer Institute, Rome, Italy. Electronic address:

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August 2017

MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.

Carcinogenesis 2017 01 17;38(1):64-75. Epub 2016 Oct 17.

Department of Life Sciences, Center for Genome Research, University of Modena and Reggio Emilia, via G. Campi 287, 41100 Modena, Italy.

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January 2017

Antibody Array as a Tool for Screening of Natural Agents in Cancer Chemoprevention.

Methods Mol Biol 2016 ;1379:189-99

Molecular Chemoprevention Unit, Molecular Medicine Area, Italian National Cancer Institute "Regina Elena", via Elio Chianesi, 53, Rome, 00144, Italy.

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September 2016

Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors.

Cancer Biol Ther 2016 ;17(1):79-82

a Department of Anatomical, Histological , Forensic and orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome , Rome , Italy.

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October 2016

Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.

Oncotarget 2015 Mar;6(8):5547-66

Translational Oncogenomic Unit, Molecular Medicine Area, Regina Elena National Cancer Institute, Rome 00144, Italy.

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March 2015

Downregulation of microRNAs 145-3p and 145-5p is a long-term predictor of postmenopausal breast cancer risk: The ORDET prospective study.

Cancer Epidemiol Biomarkers Prev 2014 Nov 29;23(11):2471-81. Epub 2014 Jul 29.

Department of Oncology, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada. Translational Oncogenomics Unit, Regina Elena Italian National Cancer Institute, Rome, Italy.

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November 2014

MicroRNA expression profiling of thymic epithelial tumors.

Lung Cancer 2014 Aug 29;85(2):197-204. Epub 2014 Apr 29.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy. Electronic address:

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August 2014

Hippo and rassf1a Pathways: A Growing Affair.

Mol Biol Int 2012 5;2012:307628. Epub 2012 Jul 5.

Molecular Chemoprevention Group, Molecular Medicine Area, Regina Elena Cancer Institute, Via Elio Chianesi 53, 00143 Rome, Italy.

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August 2012

Analytical considerations for mass spectrometry profiling in serum biomarker discovery.

Clin Lab Med 2009 Mar;29(1):57-69

Clinical Proteomics Reference Lab, Advanced Technology Program, SAIC-Frederick, NCI-Frederick, PO Box B, Frederick, MD 21702, USA.

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March 2009