Andrea Natali

Andrea Natali

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Andrea Natali

Andrea Natali

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The insulinotropic effect of a high-protein nutrient preload is mediated by the increase of plasma amino acids in type 2 diabetes.

Eur J Nutr 2019 Sep 14;58(6):2253-2261. Epub 2018 Jul 14.

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy.

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http://dx.doi.org/10.1007/s00394-018-1778-yDOI Listing
September 2019

Cardiovascular organ damage in type 2 diabetes mellitus: the role of lipids and inflammation.

Cardiovasc Diabetol 2019 05 10;18(1):61. Epub 2019 May 10.

Department of Surgical, Medical Molecular Pathology and Critical Care Medicine, University of Pisa, Via Savi 10, 56126, Pisa, Italy.

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http://dx.doi.org/10.1186/s12933-019-0865-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511166PMC
May 2019

Triglyceride-rich very low-density lipoproteins (VLDL) are independently associated with insulin secretion in a multiethnic cohort of adolescents.

Diabetes Obes Metab 2018 12 2;20(12):2905-2910. Epub 2018 Aug 2.

Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/dom.13467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231949PMC
December 2018

Defective Amplifying Pathway of β-Cell Secretory Response to Glucose in Type 2 Diabetes: Integrated Modeling of In Vitro and In Vivo Evidence.

Diabetes 2018 03 11;67(3):496-506. Epub 2017 Dec 11.

Institute of Neuroscience, National Research Council, Padua, Italy

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http://dx.doi.org/10.2337/db17-1039DOI Listing
March 2018

Reducing Cholesterol and Fat Intake Improves Glucose Tolerance by Enhancing β Cell Function in Nondiabetic Subjects.

J Clin Endocrinol Metab 2018 02;103(2):622-631

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1210/jc.2017-02089DOI Listing
February 2018

High density lipoprotein with apolipoprotein C-III is associated with carotid intima-media thickness among generally healthy individuals.

Atherosclerosis 2018 02 2;269:92-99. Epub 2018 Jan 2.

Department of Nutrition, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.12.029DOI Listing
February 2018

Modulation of postprandial glycemic responses by noncarbohydrate nutrients provides novel approaches to the prevention and treatment of type 2 diabetes.

Am J Clin Nutr 2017 08;106(2):701-702

From the Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy (AN; DT, e-mail:

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https://academic.oup.com/ajcn/article/106/2/701-702/4557640
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http://dx.doi.org/10.3945/ajcn.117.157255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525123PMC
August 2017

Gamma-glutamyltransferase, fatty liver index and hepatic insulin resistance are associated with incident hypertension in two longitudinal studies.

J Hypertens 2017 03;35(3):493-500

aService Endocrinologie-Diabétologie, CHU Rennes, Université Rennes 1, Rennes bINSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018 cUniversity Paris-Sud, University Versailles Saint-Quentin, UMRS 1018, Paris, France dClinical Physiology CNR, Cardiometabolic Risk Laboratory eDepartment of Internal Medicine, University of Pisa, Pisa, Italy fINSERM U1138 gAP-HP, Hôpital Bichat, Diabetology Endocrinology Nutrition, Université Paris Diderot, Paris, France hInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK iIRSA, La Riche jINSERM, U991, Université de Rennes 1, Rennes, France.

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http://dx.doi.org/10.1097/HJH.0000000000001204DOI Listing
March 2017

Glucose uptake saturation explains glucose kinetics profiles measured by different tests.

Am J Physiol Endocrinol Metab 2016 08 31;311(2):E346-57. Epub 2016 May 31.

CNR Institute of Neuroscience, Padua, Italy;

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http://dx.doi.org/10.1152/ajpendo.00045.2016DOI Listing
August 2016

Syphilis iridocyclitis in a patient with type 1 diabetes.

J Diabetes Investig 2016 Jul 25;7(4):641-644. Epub 2015 Dec 25.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1111/jdi.12447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931218PMC
July 2016

Clinical Phenotype and Microvascular Dynamics of Subjects with Endothelial Dysfunction as Assessed by Peripheral Tonometry.

Microcirculation 2016 Apr;23(3):230-9

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1111/micc.12268DOI Listing
April 2016

Beta-cell function is associated with carotid intima-media thickness independently of insulin resistance in healthy individuals.

J Hypertens 2016 Apr;34(4):685-91

aINSERM, U1138, Centre de Recherche des Cordeliers bUniversité Paris Diderot cDiabétologie, AP-HP, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris, France dDepartment of Experimental and Clinical Medicine, University of Pisa, Italy eInserm U-1018, CESP, Team 5 (EpReC, Renal and cardiovascular Epidemiology), UVSQ-UPS, Villejuif, France fDepartment of Endocrinology, Odense University Hospital, Odense, Denmark gInstituto de Investigación IdiPAZ, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, Spain hSteno Diabetes Center, Gentofte, Denmark iInstitute of Biomedical Engineering, National Research Council, Padova, Italy jDiabetology Department, Southern Hospital, University Hospital, Rennes, France.

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http://dx.doi.org/10.1097/HJH.0000000000000842DOI Listing
April 2016

Mechanisms through which a small protein and lipid preload improves glucose tolerance.

Diabetologia 2015 Nov 30;58(11):2503-12. Epub 2015 Jul 30.

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 57, Pisa, 56100, Italy.

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http://dx.doi.org/10.1007/s00125-015-3710-9DOI Listing
November 2015

Influence of endogenous NEFA on beta cell function in humans.

Diabetologia 2015 Oct 10;58(10):2344-51. Epub 2015 Jul 10.

Department of Clinical & Experimental Medicine, University of Pisa, Via Roma, 67, 56126, Pisa, Italy.

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http://dx.doi.org/10.1007/s00125-015-3685-6DOI Listing
October 2015

Elevated heart rate predicts β cell function in non-diabetic individuals: the RISC cohort.

Eur J Endocrinol 2015 Sep 1;173(3):409-15. Epub 2015 Jun 1.

Service Endocrinologie-DiabétologieCHU Rennes, Université Rennes 1, Rennes, FranceInserm Centre for research in Epidemiology and Population Health (CESP) U1018Villejuif, FranceParis Cardiovascular Research Centre (PARCC)INSERM UMRS 970, Paris, FranceDepartment of Internal MedicineUniversity of Pisa, Pisa, ItalyDepartment of Internal MedicineCardio-Diabetes and Core Lab, Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, ItalyService d'enseignement thérapeutique pour maladies chroniquesHôpitaux Universitaires de Genève, Geneva, SwitzerlandFaculty of Medicine University of BelgradeClinic for Endocrinology, Diabetes and Metabolic Diseases, Belgrade, SerbiaDepartment of Epidemiology and BiostatisticsEMGO Institute for Health and Care Research, Amsterdam, The NetherlandsC N R Institute of NeurosciencePadova, Italy.

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http://dx.doi.org/10.1530/EJE-15-0115DOI Listing
September 2015

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

Arterioscler Thromb Vasc Biol 2015 Jul 7;35(7):1723-31. Epub 2015 May 7.

From the Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (I.G., E.B., A.E., P.D., G.N.F., H.B., G.Ö., M.P., J.N.); Medical Research Institute, University of Dundee, Dundee, UK (H.M.C., F.K., H.C.L., F.A., J.B.); Institute of Biomedical and Clinical Science, Diabetes and Vascular Medicine, NIHR Exeter Clinical Research Facility and University of Exeter Medical School, Exeter, UK (A.C.S., K.A., F.C., K.G., D.S.); Department of Clinical and Experimental Medicine (A.N., S.P., E.V.) and Department of Surgical, Medical, Molecular and Critical Area Pathology (C.P., M.K.), University of Pisa, Pisa, Italy; and AstraZeneca, Cardiovascular and Metabolic Diseases, Mölndal, Sweden (L.-M.G., V.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305631DOI Listing
July 2015

Euglycemic clamp insulin sensitivity and longitudinal systolic blood pressure: role of sex.

Hypertension 2013 Aug 3;62(2):404-9. Epub 2013 Jun 3.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow G12 8TA, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00439DOI Listing
August 2013

Effect of mild hyperisulinemia on conduit vessel endothelial function: role of noradrenergic activation.

J Hypertens 2012 Apr;30(4):720-4

Metabolism and Hypertension Units, Department of Internal Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e32834f9882DOI Listing
April 2012

Is hyperglycemia a cardiovascular risk factor?

Diabetes Care 2011 May;34 Suppl 2:S128-31

Center for Clinical Studies, Endocrinology and Metabolic Research, GWT, Technical University Dresden, Dresden, Germany.

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http://dx.doi.org/10.2337/dc11-s207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632149PMC
May 2011

Insulin sensitivity and beta-cell function in the offspring of type 2 diabetic patients: impact of line of inheritance.

J Clin Endocrinol Metab 2010 Oct 21;95(10):4703-11. Epub 2010 Jul 21.

Department of Internal Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1210/jc.2009-2721DOI Listing
October 2010

Insulin resistance, adipose depots and gut: interactions and pathological implications.

Dig Liver Dis 2010 May 2;42(5):310-9. Epub 2010 Mar 2.

Institute of Clinical Physiology, Stable Isotope Laboratory, CNR-National Research Council, Pisa, Italy.

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http://dx.doi.org/10.1016/j.dld.2010.01.013DOI Listing
May 2010

Effects of GIK (glucose-insulin-potassium) on stress-induced myocardial ischaemia.

Clin Sci (Lond) 2010 Apr 7;119(1):37-44. Epub 2010 Apr 7.

Division of Cardiology, Pescia General Hospital, Pescia, Italy.

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http://dx.doi.org/10.1042/CS20090438DOI Listing
April 2010

Metabolic characteristics of prehypertension: role of classification criteria and gender.

J Hypertens 2009 Dec;27(12):2394-402

Department of Internal Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e3283316c31DOI Listing
December 2009

Metabolic syndrome: at the crossroads of cardiorenal risk.

J Nephrol 2009 Jan-Feb;22(1):29-38

Department of Internal Medicine, University of Pisa, Pisa, Italy.

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June 2009

Menopause, insulin resistance, and risk factors for cardiovascular disease.

Menopause 2006 Sep-Oct;13(5):809-17

Institute of Internal Medicine, Catholic University, Rome, Italy.

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http://dx.doi.org/10.1097/01.gme.0000233492.38638.74DOI Listing
September 2007

Insulin resistance, insulin response, and obesity as indicators of metabolic risk.

J Clin Endocrinol Metab 2007 Aug 15;92(8):2885-92. Epub 2007 May 15.

Department of Internal Medicine, University of Pisa, Via Roma, 67-I-56100 Pisa, Italy.

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http://dx.doi.org/10.1210/jc.2007-0334DOI Listing
August 2007

LDL resistance to oxidation: effects of lipid phenotype, autologous HDL and alanine.

Clin Chim Acta 2007 Apr 5;379(1-2):95-100. Epub 2007 Jan 5.

Department of Internal Medicine and C N R Institute of Clinical Physiology, University of Pisa School of Medicine, Pisa, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S000989810600813
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http://dx.doi.org/10.1016/j.cca.2006.12.019DOI Listing
April 2007

Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance.

Am J Physiol Endocrinol Metab 2006 Dec 14;291(6):E1144-50. Epub 2006 Feb 14.

Dept. of Internal Medicine, University of Pisa, 56122 Pisa, Italy.

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http://dx.doi.org/10.1152/ajpendo.00571.2005DOI Listing
December 2006

Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein.

J Clin Endocrinol Metab 2006 Nov 22;91(11):4628-34. Epub 2006 Aug 22.

Consiglio Nazionale delle Richerche Institute of Clinical Physiology, Via Moruzzi, 1, 56124 Pisa, Italy.

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http://dx.doi.org/10.1210/jc.2005-2559DOI Listing
November 2006

Coronary atherosclerosis and alcohol consumption: angiographic and mortality data.

Arterioscler Thromb Vasc Biol 2006 Jul 20;26(7):1607-12. Epub 2006 Apr 20.

Department of Internal Medicine and CNR Institute of Clinical Physiology, University of Pisa School of Medicine, Pisa, Italy.

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http://dx.doi.org/10.1161/01.ATV.0000222929.99098.1fDOI Listing
July 2006

Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes.

Diabetes 2006 Apr;55(4):1133-40

Department of Internal Medicine and CNR Institute of Clinical Physiology, University of Pisa, Via Roma, 67, 56100 Pisa, Italy.

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http://dx.doi.org/10.2337/diabetes.55.04.06.db05-1076DOI Listing
April 2006

Muscle metabolism and exercise tolerance in subclinical hypothyroidism: a controlled trial of levothyroxine.

J Clin Endocrinol Metab 2005 Jul 26;90(7):4057-62. Epub 2005 Apr 26.

Department of Internal Medicine, and Consiglio Nazionale delle Ricerche Institute of Clinical Physiology, University of Pisa School of Medicine, Via Roma 67, 56126 Pisa, Italy.

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http://dx.doi.org/10.1210/jc.2004-2344DOI Listing
July 2005

Characterization of beta-cell function impairment in first-degree relatives of type 2 diabetic subjects: modeling analysis of 24-h triple-meal tests.

Am J Physiol Endocrinol Metab 2005 Mar 2;288(3):E541-6. Epub 2004 Nov 2.

Consiglio Nazionale delle Ricerche Institute of Biomedical Engineering, Padua, Italy.

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http://dx.doi.org/10.1152/ajpendo.00175.2004DOI Listing
March 2005

beta-cell function in obesity: effects of weight loss.

Diabetes 2004 Dec;53 Suppl 3:S26-33

Department of Internal Medicine, Via Savi, 8, 56126 Pisa, Italy.

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http://dx.doi.org/10.2337/diabetes.53.suppl_3.s26DOI Listing
December 2004

Hypertension, insulin resistance, and the metabolic syndrome.

Endocrinol Metab Clin North Am 2004 Jun;33(2):417-29

Department of Internal Medicine and CNRS Institute of Clinical Physiology, Univeristy of Pisa School of Medicine, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S088985290400024
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http://dx.doi.org/10.1016/j.ecl.2004.03.007DOI Listing
June 2004

Vascular effects of improving metabolic control with metformin or rosiglitazone in type 2 diabetes.

Diabetes Care 2004 Jun;27(6):1349-57

Department of Internal Medicine, CNR Institute of Clinical Physiology, University of Pisa, Via Roma 67, 56100 Pisa, Italy.

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http://dx.doi.org/10.2337/diacare.27.6.1349DOI Listing
June 2004

Erythrocyte sedimentation rate, coronary atherosclerosis, and cardiac mortality.

Eur Heart J 2003 Apr;24(7):639-48

Department of Internal Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.1016/s0195-668x(02)00741-8DOI Listing
April 2003

Metabolic effects of combined antihypertensive treatment in patients with essential hypertension.

J Cardiovasc Pharmacol 2002 Dec;40(6):916-21

National Research Council (CNR) Institute of Clinical Physiology and Department of Internal Medicine, University of Pisa School of Medicine, Pisa, Italy.

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http://dx.doi.org/10.1097/00005344-200212000-00013DOI Listing
December 2002

Effect of acute hyperglycemia on insulin secretion in humans.

Diabetes 2002 Feb;51 Suppl 1:S130-3

Metabolism Unit, CNR Institute of Clinical Physiology, University of Pisa, Via Savi 8, 56126 Pisa, Italy.

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http://dx.doi.org/10.2337/diabetes.51.2007.s130DOI Listing
February 2002