Publications by authors named "Andrea Modesti"

80Publications

Targeting the tumor immune microenvironment with "nutraceuticals": From bench to clinical trials.

Pharmacol Ther 2020 Oct 9:107700. Epub 2020 Oct 9.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy; CIMER, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2020.107700DOI Listing
October 2020

Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies.

Int J Mol Sci 2020 Sep 10;21(18). Epub 2020 Sep 10.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21186635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555128PMC
September 2020

SARS-COV-2 and infectivity: Possible increase in infectivity associated to integrin motif expression.

J Med Virol 2020 Apr 4. Epub 2020 Apr 4.

Dipartimento di Scienze Cliniche e Medicina Traslazionale, Università degli Studi di Roma Tor Vergata Facoltà di Medicina e Chirurgia, Roma, Italy.

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http://dx.doi.org/10.1002/jmv.25831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228266PMC
April 2020

Tumor antigens heterogeneity and immune response-targeting neoantigens in breast cancer.

Semin Cancer Biol 2019 Nov 4. Epub 2019 Nov 4.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.10.023DOI Listing
November 2019

In vivo and in vitro inhibition of osteosarcoma growth by the pan Bcl-2 inhibitor AT-101.

Invest New Drugs 2020 06 2;38(3):675-689. Epub 2019 Jul 2.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s10637-019-00827-yDOI Listing
June 2020

Multifaceted Role of the Placental Growth Factor (PlGF) in the Antitumor Immune Response and Cancer Progression.

Int J Mol Sci 2019 Jun 18;20(12). Epub 2019 Jun 18.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20122970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627047PMC
June 2019

Polyphenols as Immunomodulatory Compounds in the Tumor Microenvironment: Friends or Foes?

Int J Mol Sci 2019 Apr 6;20(7). Epub 2019 Apr 6.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20071714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479528PMC
April 2019

The crossroads between cancer immunity and autoimmunity: antibodies to self antigens.

Front Biosci (Landmark Ed) 2017 03 1;22:1289-1329. Epub 2017 Mar 1.

Dept. of Clinical Sciences and Translational Medicine, Faculty of Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy,

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http://dx.doi.org/10.2741/4545DOI Listing
March 2017

(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice.

Int J Food Sci Nutr 2017 May 27;68(3):298-312. Epub 2016 Sep 27.

a Department of Clinical Sciences and Translational Medicine, Faculty of Medicine , University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/09637486.2016.1236077DOI Listing
May 2017

Physical exercise modulates the level of serum MMP-2 and MMP-9 in patients with breast cancer.

Oncol Lett 2016 Sep 20;12(3):2119-2126. Epub 2016 Jul 20.

Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Rome 00133, Italy.

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http://dx.doi.org/10.3892/ol.2016.4887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998658PMC
September 2016

Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines .

Oncol Lett 2016 Jun 27;11(6):4224-4234. Epub 2016 Apr 27.

Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Rome I-00133, Italy.

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http://dx.doi.org/10.3892/ol.2016.4506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888082PMC
June 2016

The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium.

Nutrients 2016 May 9;8(5). Epub 2016 May 9.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Rome 00133, Italy.

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http://dx.doi.org/10.3390/nu8050275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882688PMC
May 2016

In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatment.

Int J Mol Sci 2015 Apr 24;16(5):9236-82. Epub 2015 Apr 24.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Rome 00133, Italy.

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http://dx.doi.org/10.3390/ijms16059236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463587PMC
April 2015

Macrophage induced gelsolin in response to Group B Streptococcus (GBS) infection.

Cell Microbiol 2015 Jan 9;17(1):79-104. Epub 2014 Sep 9.

Department of Experimental Medicine, Perugia University, Perugia, Italy.

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http://dx.doi.org/10.1111/cmi.12338DOI Listing
January 2015

Health care delivery in type 2 diabetes. A survey in an Italian primary care practice.

Prim Care Diabetes 2015 Feb 5;9(1):9-14. Epub 2014 Jun 5.

Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica, Università di Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pcd.2014.04.008DOI Listing
February 2015

Fracture healing: from basic science to role of nutrition.

Front Biosci (Landmark Ed) 2014 Jun 1;19:1162-75. Epub 2014 Jun 1.

Dept. of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Italy.

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http://dx.doi.org/10.2741/4273DOI Listing
June 2014

Poxvirus-based vaccines for cancer immunotherapy: new insights from combined cytokines/co-stimulatory molecules delivery and "uncommon" strains.

Anticancer Agents Med Chem 2014 Feb;14(2):183-9

Department of Clinical Sciences and Translational Medicine, Faculty of Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Building F Sud, 2nd floor, Room 222.

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http://dx.doi.org/10.2174/18715206113136660376DOI Listing
February 2014

Tendon's ultrastructure.

Muscles Ligaments Tendons J 2013 Jan 21;3(1):2-6. Epub 2013 May 21.

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.11138/mltj/2013.3.1.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676160PMC
January 2013

All is around ECM of tendons!?

Muscles Ligaments Tendons J 2013 Jan 21;3(1). Epub 2013 May 21.

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.11138/mltj/2013.3.1.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676158PMC
January 2013

Inhibition of ErbB receptors, Hedgehog and NF-kappaB signaling by polyphenols in cancer.

Front Biosci (Landmark Ed) 2013 Jun 1;18:1290-310. Epub 2013 Jun 1.

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.2741/4180DOI Listing
June 2013

Effects of vitamin C on health: a review of evidence.

Front Biosci (Landmark Ed) 2013 Jun 1;18:1017-29. Epub 2013 Jun 1.

Department of G.F. Ingrassia, Section of Hygiene and Public Health, University of Catania, Catania, Italy.

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http://dx.doi.org/10.2741/4160DOI Listing
June 2013

KSHV ORF67 encoded lytic protein localizes on the nuclear membrane and alters emerin distribution.

Virus Res 2013 Aug 23;175(2):143-50. Epub 2013 Apr 23.

Istituto Pasteur Fondazione Cenci Bolognetti, Dipartimento di Medicina Sperimentale, Sapienza Università di Roma, Italy.

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http://dx.doi.org/10.1016/j.virusres.2013.04.001DOI Listing
August 2013

The effects of dietary flavonoids on the regulation of redox inflammatory networks.

Front Biosci (Landmark Ed) 2012 Jun 1;17:2396-418. Epub 2012 Jun 1.

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.2741/4061DOI Listing
June 2012

Carcinoembryonic antigen (CEA)-based cancer vaccines: recent patents and antitumor effects from experimental models to clinical trials.

Recent Pat Anticancer Drug Discov 2012 Sep;7(3):265-96

Department of Clinical Sciences and Translational Medicine Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.2174/157489212801820020DOI Listing
September 2012

Immunity and malignant mesothelioma: from mesothelial cell damage to tumor development and immune response-based therapies.

Cancer Lett 2012 Sep 3;322(1):18-34. Epub 2012 Mar 3.

Department of Experimental Medicine and Biochemical Sciences, University of Rome, Tor Vergata, Italy.

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http://dx.doi.org/10.1016/j.canlet.2012.02.034DOI Listing
September 2012

Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis.

Front Biosci (Landmark Ed) 2012 Jan 1;17:498-508. Epub 2012 Jan 1.

Department of Experimental Medicine, University of Rome, Sapienza, Rome, Italy.

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http://dx.doi.org/10.2741/3940DOI Listing
January 2012

Nutritional stress and arginine auxotrophy confer high sensitivity to chloroquine toxicity in mesothelioma cells.

Am J Respir Cell Mol Biol 2012 Apr 10;46(4):498-506. Epub 2011 Nov 10.

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Italy.

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http://dx.doi.org/10.1165/rcmb.2011-0195OCDOI Listing
April 2012

Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents.

Recent Pat Inflamm Allergy Drug Discov 2011 Sep;5(3):200-20

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata , Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.2174/187221311797264937DOI Listing
September 2011

Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection.

Front Biosci (Landmark Ed) 2011 Jan 1;16:1833-43. Epub 2011 Jan 1.

Department of Experimental Medicine and Biochemical Sciences, University of Rome, Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.2741/3825DOI Listing
January 2011

Apigenin induces apoptosis and impairs head and neck carcinomas EGFR/ErbB2 signaling.

Front Biosci (Landmark Ed) 2011 Jan 1;16:1060-8. Epub 2011 Jan 1.

Department of Experimental Medicine, University of Rome, Sapienza, Rome, Italy.

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http://dx.doi.org/10.2741/3735DOI Listing
January 2011

Topical use of sucralfate in epithelial wound healing: clinical evidences and molecular mechanisms of action.

Recent Pat Inflamm Allergy Drug Discov 2010 Jan;4(1):25-36

Department of Experimental Medicine, University of Rome 'Sapienza', Rome, Italy.

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http://dx.doi.org/10.2174/187221310789895649DOI Listing
January 2010

Placenta growth factor expression has prognostic value in malignant pleural mesothelioma.

Ann Thorac Surg 2009 Aug;88(2):426-31

Department of Thoracic Surgery, Tor Vergata University, Rome, Italy.

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http://dx.doi.org/10.1016/j.athoracsur.2009.04.038DOI Listing
August 2009

Differential effects of malignant mesothelioma cells on THP-1 monocytes and macrophages.

Int J Oncol 2009 Feb;34(2):543-50

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, I-00133 Rome, Italy.

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February 2009

Molecular targets and targeted therapies for malignant mesothelioma.

Curr Med Chem 2008 ;15(9):855-67

Department of Experimental Medicine and Biochemical Sciences, Tor Vergata University, Via Montpellier 1, Rome, Italy.

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http://dx.doi.org/10.2174/092986708783955446DOI Listing
July 2008

Long-lasting tissue inflammatory processes trigger autoimmune responses to extracellular matrix molecules.

Int Rev Immunol 2008 ;27(3):137-75

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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http://www.tandfonline.com/doi/full/10.1080/0883018080193928
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http://dx.doi.org/10.1080/08830180801939280DOI Listing
August 2008

Recombinant erythropoietin differently affects proliferation of mesothelioma cells but not sensitivity to cisplatin and pemetrexed.

Cancer Chemother Pharmacol 2008 Apr 6;61(5):893-901. Epub 2007 Oct 6.

Department of Experimental Medicine and Biochemical Sciences, Università degli Studi di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://link.springer.com/10.1007/s00280-007-0608-3
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http://dx.doi.org/10.1007/s00280-007-0608-3DOI Listing
April 2008

Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane-type metalloproteinase MMP-14 recognize collagen I and enzymatically process the two alpha-chains.

J Mol Biol 2007 May 2;368(4):1101-13. Epub 2007 Mar 2.

Department of Experimental Medicine and Biochemical Sciences, University of Roma Tor Vergata, Via Montpellier 1, I-00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.jmb.2007.02.076DOI Listing
May 2007

Alpha-linolenic acid-enriched diet prevents myocardial damage and expands longevity in cardiomyopathic hamsters.

Am J Pathol 2006 Dec;169(6):1913-24

Laboratorio di Cardiologia Molecolare e Cellulare, Dipartimento di Medicina Interna, Università di Roma Tor Vergata, Via Montpellier, 1, 00133 Roma, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762468PMC
http://dx.doi.org/10.2353/ajpath.2006.051320DOI Listing
December 2006

Extremely low frequency electromagnetic field exposure promotes differentiation of pituitary corticotrope-derived AtT20 D16V cells.

Bioelectromagnetics 2006 Dec;27(8):641-51

Consiglio Nazionale delle Ricerche Istituto di Neurobiologia e Medicina Molecolare, Rome, Italy.

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http://dx.doi.org/10.1002/bem.20255DOI Listing
December 2006

Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with Charcot-Marie-tooth disease type 1A.

Muscle Nerve 2006 Mar;33(3):342-9

Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Via Montpellier 1, I-00133 Roma, Italy.

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http://dx.doi.org/10.1002/mus.20460DOI Listing
March 2006

Role of apoptosis in intracranial aneurysm rupture.

J Neurosurg 2004 Dec;101(6):1018-25

Department of Neurosurgery, Catholic University, Institute of Experimental Medicine and Biochemical Sciences, Rome, Italy.

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http://dx.doi.org/10.3171/jns.2004.101.6.1018DOI Listing
December 2004

HMBA induces cell death and potentiates doxorubicin toxicity in malignant mesothelioma cells.

Cancer Chemother Pharmacol 2004 Nov;54(5):398-406

Department of Experimental Medicine and Biochemical Sciences, Tor Vergata University, Rome, Italy.

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http://dx.doi.org/10.1007/s00280-004-0838-6DOI Listing
November 2004

The interaction of tenascin-C with fibronectin modulates the migration and specific metalloprotease activity in human mesothelioma cell lines of different histotype.

Int J Oncol 2004 Sep;25(3):745-50

Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.

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September 2004

Identification of a new missense mutation in the mtDNA of hereditary hypertrophic, but not dilated cardiomyopathic hamsters.

Mol Cell Biochem 2003 Oct;252(1-2):73-81

Laboratorio di Cardiologia Molecolare e Cellulare, Dipartimento di Medicina Interna, Università di Roma 'Tor Vergata', Roma, Italy.

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http://dx.doi.org/10.1023/a:1025542731335DOI Listing
October 2003

Radiolabelled lymphokines and growth factors for in vivo imaging of inflammation, infection and cancer.

Trends Immunol 2003 Jul;24(7):395-402

Nuclear Medicine Unit, Department of Clinical Sciences, University La Sapienza, Via del Policlinico 155, 00161, Roma, Italy.

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http://dx.doi.org/10.1016/s1471-4906(03)00174-1DOI Listing
July 2003

Peripheral nerve extracellular matrix remodeling in Charcot-Marie-Tooth type I disease.

Acta Neuropathol 2002 Sep 16;104(3):287-96. Epub 2002 May 16.

Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Università di Roma Tor Vergata, Via di Tor Vergata 135, 00133 Rome, Italy.

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http://dx.doi.org/10.1007/s00401-002-0558-0DOI Listing
September 2002