Andrea Malaspina

Andrea Malaspina

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Andrea Malaspina

Publications by authors named "Andrea Malaspina"

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Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity.

Neurology 2019 Aug 7;93(9):e895-e907. Epub 2019 Aug 7.

From the Neuroradiological Academic Unit (C.D.J.S., S.J.W., A.E., S.S., T.A.Y., J.S.T.), and MRC Centre for Neuromuscular Diseases (U.K., L.Z., K.T., R.S.H., N.S., K.S., M.G.H., L.G., J.M.M., P.F.), UCL Queen Square Institute of Neurology, University College London; Blizard Institute (A.M.), Queen Mary University of London, UK; and Department of Radiology (U.K.), University Hospital Tulln, Karl Landsteiner University of Health Sciences, Tulln, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000008009DOI Listing
August 2019

Neurofilaments in pre-symptomatic ALS and the impact of genotype.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Aug 21:1-11. Epub 2019 Aug 21.

Neuroscience Center, Blizard, Institute of Cell and Molecular Medicine, Barts & the London School of Medicine & Dentistry , London , UK.

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http://dx.doi.org/10.1080/21678421.2019.1646769DOI Listing
August 2019

Safety and tolerability of Triumeq in amyotrophic lateral sclerosis: the Lighthouse trial.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Jul 8:1-10. Epub 2019 Jul 8.

b King's College London, Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience , London , United Kingdom.

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http://dx.doi.org/10.1080/21678421.2019.1632899DOI Listing
July 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy.

Neurology 2019 Mar 20;92(11):e1205-e1211. Epub 2019 Feb 20.

From the Institute of Neurology (V.L., O.J.Z., L.Z., C.H., M.F., C.-H.L., B.M., H.Z., A.H., L.G., M.H., P.F.), University College London Institute of Neurology, Queen Square, London; Blizard Institute (V.L., A.M.), Queen Mary, University of London, UK; Department of Neurosciences (G.Q., I.M., C.B., G.S.), University of Padova, Italy; Department of Neurology (C.-H.L.), China Medical University Hospital, Taiwan; Basildon Hospital (K.A.), UK; Department of Physiology, Anatomy and Genetics (C.R.), University of Oxford; UK Dementia Research Institute at UCL (H.Z., A.H.), London, UK; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital; and the Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511101PMC
March 2019

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis.

Mol Neurodegener 2018 11 7;13(1):60. Epub 2018 Nov 7.

Neuroscience and Trauma Centre, Blizard Institute, Barts and The School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, City of London, Greater London, E1 2AT, UK.

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https://molecularneurodegeneration.biomedcentral.com/article
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http://dx.doi.org/10.1186/s13024-018-0292-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223075PMC
November 2018

The proteome of neurofilament-containing protein aggregates in blood.

Biochem Biophys Rep 2018 Jul 25;14:168-177. Epub 2018 May 25.

Centre for Neuroscience and Trauma, Queen Mary University of London, Blizard Institute, Barts and The School of Medicine and Dentistry, London, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S24055808183001
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http://dx.doi.org/10.1016/j.bbrep.2018.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986704PMC
July 2018

Neurofilament light: A candidate biomarker of presymptomatic amyotrophic lateral sclerosis and phenoconversion.

Ann Neurol 2018 07 16;84(1):130-139. Epub 2018 Aug 16.

Neuroscience Center, Blizard, Institute of Cell and Molecular Medicine, Barts & the London School of Medicine & Dentistry, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25276DOI Listing
July 2018

No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation.

J Neurol 2018 May 3;265(5):1089-1095. Epub 2018 Mar 3.

The Royal London Hospital, Emergency Care and Acute Medicine Clinical Academic Group, Neuroscience, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1007/s00415-018-8801-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937900PMC
May 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Plasma neurofilament light chain concentration in the inherited peripheral neuropathies.

Neurology 2018 02 10;90(6):e518-e524. Epub 2018 Jan 10.

From the Department of Psychiatry and Neurochemistry (Å.S., H.Z., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z., K.B.), Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology; Trauma and Neuroscience Centre (R.A., A.M.), Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London; and MRC Centre for Neuromuscular Diseases (M.L., M.M.R., A.M.R.), UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818017PMC
February 2018

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2017 02 31;18(1-2):1-9. Epub 2016 Aug 31.

a Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.1080/21678421.2016.1221433DOI Listing
February 2017

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis.

Neurol Neuroimmunol Neuroinflamm 2016 Aug 1;3(4):e244. Epub 2016 Jun 1.

Centre for Neuroscience & Trauma (C.L., F.O., J.K., A.M.) and Centre of Primary Care and Public Health (V.G.), Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London; Sobell Department of Motor Neuroscience and Movement Disorders (C.L., P.F., L.G.), MRC Centre for Neuromuscular Diseases (P.F., L.G.), MRC Unit for Lifelong Health and Ageing (N.S.), Department of Molecular Neuroscience (K.S.), and Department of Clinical Neuroscience (R.O.), UCL Institute of Neurology; Basildon and Thurrock University Hospitals (K.A., A.M.), NHS Foundation Trust, Basildon; William Harvey Hospital (F.O.), Kent; Proteome Sciences plc (E.L.), South Wing Laboratory, Institute of Psychiatry, UK; Neurology (J.K.), University Hospital Basel, Switzerland; Department of Immunobiology (T.T.), King's College London; National Hospital for Neurology and Neurosurgery (N.S., R.H., R.O.), London; Musgrove Park Hospital (M.F.), Taunton; and Department of Medical Statistics (N.P.), London School of Hygiene and Tropical Medicine, UK.

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http://dx.doi.org/10.1212/NXI.0000000000000244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897985PMC
August 2016

Non-neuronal Cells in ALS: Role of Glial, Immune cells and Blood-CNS Barriers.

Brain Pathol 2016 Mar;26(2):248-57

Neuroimmunology Unit, Queen Mary University of London, Neuroscience Centre, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/bpa.12352DOI Listing
March 2016

CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia.

Brain 2016 Feb 11;139(Pt 2):e9. Epub 2015 Sep 11.

1 Department of Neurodegenerative Disease, University College London Institute of Neurology, Queen Square, London WC1N 3BG, UK 4 Sobell Department of Motor Neuroscience and Movement Disorders, Queen Square, London, WC1N 3BG, UK

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http://dx.doi.org/10.1093/brain/awv223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963427PMC
February 2016

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS.

Ann Clin Transl Neurol 2015 Jul 25;2(7):748-55. Epub 2015 May 25.

Nuffield Department of Clinical Neurosciences, University of Oxford Oxford, United Kingdom.

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http://dx.doi.org/10.1002/acn3.212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531057PMC
July 2015

Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis.

Neurology 2015 Jun 1;84(22):2247-57. Epub 2015 May 1.

From the Centre for Neuroscience & Trauma (C.-H.L., G.G., J.K., A.M.), Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London; Sobell Department of Motor Neuroscience and Movement Disorders (C.-H.L., L.G.), Departments of Neuroinflammation (A.P.), Neurodegenerative Disease (P.F.), Molecular Neuroscience (K.S.), and Clinical Neuroscience (R.O.), and MRC Centre for Neuromuscular Diseases (R.O., L.G.), UCL Institute of Neurology, London; MRC Integrative Epidemiology Unit (C.M.-W.), University of Bristol; Nuffield Department of Clinical Neurosciences (E.G., K.T., M.R.T.), University of Oxford; Department of Medical Statistics (N.P.), London School of Hygiene and Tropical Medicine, London, UK; UmanDiagnostics (N.N.), Umeå, Sweden; Medicine Clinical Trial Unit (M.F.), Musgrove Park Hospital, Taunton, UK; National Hospital for Neurology and Neurosurgery (R.O., R.H., A.M.), London, UK; Neurology (J.K.), University Hospital Basel, Switzerland; North-East London and Essex MND Care and Research Centre (A.M.), London; and Basildon and Thurrock University Hospitals NHS Foundation Trust (A.M.), Basildon, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456658PMC
June 2015

Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study.

J Neurol Neurosurg Psychiatry 2015 May 9;86(5):565-73. Epub 2014 Jul 9.

Centre for Neuroscience & Trauma, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK Basildon and Thurrock University Hospitals NHS Foundation Trust, Essex, UK North-East London and Essex MND Care and Research Centre, London, UK.

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http://dx.doi.org/10.1136/jnnp-2014-307672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413806PMC
May 2015

Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective.

Int Immunol 2015 Mar 25;27(3):117-29. Epub 2014 Oct 25.

Neuroscience and Trauma Centre, Blizard Building, Institute of Cell and Molecular Medicine, Neuroimmunology Department, Barts and the London School of Medicine and Dentistry, 2 Newark Street, London, E1 2AT, UK Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/intimm/dxu099DOI Listing
March 2015

Investigation of next-generation sequencing technologies as a diagnostic tool for amyotrophic lateral sclerosis.

Neurobiol Aging 2015 Mar 20;36(3):1600.e5-8. Epub 2014 Dec 20.

Reta Lila Weston Institute, UCL Institute of Neurology, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.017DOI Listing
March 2015

Antibodies to GABAA receptor α1 and γ2 subunits: clinical and serologic characterization.

Neurology 2015 Mar 30;84(12):1233-41. Epub 2015 Jan 30.

From the Nuffield Department of Clinical Neurosciences (P.P., R.P., S.M., A.N., S.R.I., C.B., D.B., B.L., P.W., A.V.) and the Department of Physiology, Anatomy and Genetics (H.B.K.), University of Oxford; St George's Healthcare NHS Trust (J.A.C.), Tooting, London; the Centre for Neuroscience & Trauma, Blizard Institute (A.M.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London; and The Walton Centre Foundation Trust (A.J.), Liverpool, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366091PMC
March 2015

Neurofilament light antibodies in serum reflect response to natalizumab treatment in multiple sclerosis.

Mult Scler 2014 Sep 10;20(10):1355-62. Epub 2014 Feb 10.

Neuroimmunology Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK

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http://journals.sagepub.com/doi/10.1177/1352458514521887
Publisher Site
http://dx.doi.org/10.1177/1352458514521887DOI Listing
September 2014

Correlation of clinical and molecular features in spinal bulbar muscular atrophy.

Neurology 2014 Jun 9;82(23):2077-84. Epub 2014 May 9.

From the Department of Neurodegenerative Disease (P.F., L.M., T.C., E.M.C.F.), Sobell Department of Motor Neuroscience and Movement Disorders (N.N., L.G.), and MRC Centre for Neuromuscular Disease (P.F., N.N., I.S., A.C., E.M.C.F., L.G., M.G.H.), UCL Institute of Neurology, Queen Square, London; Neurogenetics Unit (S.P.), National Hospital for Neurology and Neurosurgery, Queen Square, London; and Centre for Neuroscience & Trauma (A.M.), Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000000507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075620PMC
June 2014

Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.

PLoS One 2013 20;8(9):e75091. Epub 2013 Sep 20.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom ; Bone & Joint Research Unit, John Vane Science Centre, Queen Mary University of London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075091PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779219PMC
May 2014

Immune reactivity to neurofilament proteins in the clinical staging of amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2014 Mar 27;85(3):274-8. Epub 2013 Sep 27.

Neuroimmunology Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK.

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http://dx.doi.org/10.1136/jnnp-2013-305494DOI Listing
March 2014

Management of sialorrhoea in motor neuron disease: a survey of current UK practice.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 7;14(7-8):521-7. Epub 2013 May 7.

Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital , Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.3109/21678421.2013.790452DOI Listing
December 2013

A comparative study of CSF neurofilament light and heavy chain protein in MS.

Mult Scler 2013 Oct 25;19(12):1597-603. Epub 2013 Mar 25.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK.

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http://dx.doi.org/10.1177/1352458513482374DOI Listing
October 2013

Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS.

PLoS One 2012 16;7(7):e40998. Epub 2012 Jul 16.

Sobell Department of Motor Neuroscience and Movement Disorders, MRC Centre for Neuromuscular Disorders, UCL Institute of Neurology, University College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040998PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397981PMC
January 2013

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications.

Proc Natl Acad Sci U S A 2013 Jan 31;110(3):832-41. Epub 2012 Dec 31.

William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1209362110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549094PMC
January 2013

Spinal cord trauma and the molecular point of no return.

Mol Neurodegener 2012 Feb 8;7. Epub 2012 Feb 8.

Centre for Neuroscience and Trauma, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.

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http://dx.doi.org/10.1186/1750-1326-7-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299607PMC
February 2012

A method to solubilise protein aggregates for immunoassay quantification which overcomes the neurofilament "hook" effect.

J Neurosci Methods 2011 Feb 4;195(2):143-50. Epub 2010 Dec 4.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London WC1N3BG, UK.

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http://dx.doi.org/10.1016/j.jneumeth.2010.11.026DOI Listing
February 2011

The human G93A-SOD1 mutation in a pre-symptomatic rat model of amyotrophic lateral sclerosis increases the vulnerability to a mild spinal cord compression.

BMC Genomics 2010 Nov 15;11:633. Epub 2010 Nov 15.

Centre for Neuroscience and Trauma, Blizard Institute of Cell and Molecular Science, Queen Mary University of London, UK.

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http://dx.doi.org/10.1186/1471-2164-11-633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020590PMC
November 2010

Comparative analysis of the time-dependent functional and molecular changes in spinal cord degeneration induced by the G93A SOD1 gene mutation and by mechanical compression.

BMC Genomics 2008 Oct 23;9:500. Epub 2008 Oct 23.

Neuroscience Centre, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, Whitechapel, London E1 2AT, UK.

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http://dx.doi.org/10.1186/1471-2164-9-500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585103PMC
October 2008

Is the modulation of retinoid and retinoid-associated signaling a future therapeutic strategy in neurological trauma and neurodegeneration?

J Neurochem 2008 Feb 22;104(3):584-95. Epub 2007 Nov 22.

Neuroscience Centre, Institute of Cell and Molecular Science, Barts and the Royal London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05071.xDOI Listing
February 2008

Retinoid receptors in chronic degeneration of the spinal cord: observations in a rat model of amyotrophic lateral sclerosis.

J Neurochem 2007 Dec 13;103(5):1821-33. Epub 2007 Sep 13.

Neuroscience Centre, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04893.xDOI Listing
December 2007

A review of the functional role and of the expression profile of retinoid signaling and of nuclear receptors in human spinal cord.

Brain Res Bull 2007 Mar 1;71(5):437-46. Epub 2006 Dec 1.

Neuroscience Centre, Institute of Cell and Molecular Science, Queen Mary University, 4 Newark Street, Whitechapel, London E1 2AT, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2006.10.032DOI Listing
March 2007

Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2006 Dec;7(4):227-34

Experimental Neurobiology, Neurological Institute IRCCS C Mondino, Pavia, Italy.

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http://dx.doi.org/10.1080/17482960600864413DOI Listing
December 2006

Spinal cord molecular profiling provides a better understanding of amyotrophic lateral sclerosis pathogenesis.

Brain Res Brain Res Rev 2004 Jul;45(3):213-29

Department of Neuromuscular Diseases, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, London W14 8RF, UK.

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http://dx.doi.org/10.1016/j.brainresrev.2004.04.002DOI Listing
July 2004

Disease clustering: the example of ALS, PD, dementia and hereditary ataxias in Italy.

Funct Neurol 2002 Oct-Dec;17(4):177-82

Laboratory of Experimental Neurobiology, IRCCS C. Mondino Institute of Neurology, University of Pavia, Italy.

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May 2003