Andrea M Woltman

Andrea M Woltman

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Andrea M Woltman

Andrea M Woltman

Publications by authors named "Andrea M Woltman"

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Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients.

Antiviral Res 2020 Feb 17:104746. Epub 2020 Feb 17.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2020.104746DOI Listing
February 2020

Gender-specific effects of raising Year 1 standards on medical students' academic performance and stress levels.

Med Educ 2020 Jan 21. Epub 2020 Jan 21.

Institute of Medical Education Research Rotterdam, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/medu.14068DOI Listing
January 2020

Elevated serum levels of soluble CD14 in HBeAg-positive chronic HBV patients upon Peginterferon treatment are associated with treatment response.

J Viral Hepat 2019 Sep 3;26(9):1076-1085. Epub 2019 Jun 3.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/jvh.13127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852593PMC
September 2019

TLR7 polymorphism, sex and chronic HBV infection influence plasmacytoid DC maturation by TLR7 ligands.

Antiviral Res 2018 09 28;157:27-37. Epub 2018 Jun 28.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2018.06.015DOI Listing
September 2018

Transcriptional patterns associated with BDCA3 expression on BDCA1 myeloid dendritic cells.

Immunol Cell Biol 2018 03 1;96(3):330-336. Epub 2018 Feb 1.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/imcb.12002DOI Listing
March 2018

The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.

PLoS One 2016 16;11(8):e0161235. Epub 2016 Aug 16.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161235PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987041PMC
August 2017

To target or not to target viral antigens in HBV related HCC?

J Hepatol 2015 Jun 21;62(6):1449-50. Epub 2015 Feb 21.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2015.01.043DOI Listing
June 2015

BDCA3(+)CLEC9A(+) human dendritic cell function and development.

Semin Cell Dev Biol 2015 May 6;41:39-48. Epub 2014 Jun 6.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2014.05.016DOI Listing
May 2015

BDCA3 expression is associated with high IFN-λ production by CD34(+)-derived dendritic cells generated in the presence of GM-CSF, IL-4, and/or TGF-β.

Eur J Immunol 2015 May 14;45(5):1471-81. Epub 2015 Feb 14.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1002/eji.201444802
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http://dx.doi.org/10.1002/eji.201444802DOI Listing
May 2015

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

J Infect Dis 2015 Apr 31;211(8):1268-78. Epub 2014 Oct 31.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiu599DOI Listing
April 2015

The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

J Hepatol 2014 Sep 4;61(3):660-71. Epub 2014 May 4.

Dept. of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.04.026DOI Listing
September 2014

Understanding MHC class I presentation of viral antigens by human dendritic cells as a basis for rational design of therapeutic vaccines.

Front Immunol 2014 23;5:182. Epub 2014 Apr 23.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam , Rotterdam , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2014.00182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005948PMC
June 2014

Intrahepatic natural killer cell activation, but not function, is associated with HBsAg levels in patients with HBeAg-negative chronic hepatitis B.

Liver Int 2014 Mar 25;34(3):396-404. Epub 2013 Jul 25.

Liver Unit, Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1111/liv.12272
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http://dx.doi.org/10.1111/liv.12272DOI Listing
March 2014

Identification of a novel CD40 ligand for targeted imaging of inflammatory plaques by phage display.

FASEB J 2013 Oct 29;27(10):4136-46. Epub 2013 Jul 29.

2Department of Pathology, University Hospital Maastricht, Debeijelaan 25, 6229 HX Maastricht, The Netherlands.

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http://dx.doi.org/10.1096/fj.12-224667DOI Listing
October 2013

Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients.

Mol Immunol 2013 Jan 20;53(1-2):72-8. Epub 2012 Jul 20.

Liver Unit, Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, 's Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2012.06.016DOI Listing
January 2013

PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.

Blood 2012 Dec 22;120(25):4982-91. Epub 2012 Oct 22.

Departments of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-02-413229DOI Listing
December 2012

Restoration of TLR3-activated myeloid dendritic cell activity leads to improved natural killer cell function in chronic hepatitis B virus infection.

J Virol 2012 Apr 8;86(8):4102-9. Epub 2012 Feb 8.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/JVI.07000-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318629PMC
April 2012

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy.

Blood 2012 Apr 8;119(15):3383-93. Epub 2012 Feb 8.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-11-37
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http://dx.doi.org/10.1182/blood-2011-11-370130DOI Listing
April 2012

Polymorphisms near IL28B and serologic response to peginterferon in HBeAg-positive patients with chronic hepatitis B.

Gastroenterology 2012 Mar 19;142(3):513-520.e1. Epub 2011 Nov 19.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2011.11.025DOI Listing
March 2012

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection.

Clin Immunol 2011 Aug 18;140(2):130-41. Epub 2010 Dec 18.

Department of Medical Oncology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.clim.2010.11.010DOI Listing
August 2011

Tight control of STAT5 activity determines human CD34-derived interstitial dendritic cell and langerhans cell development.

J Immunol 2011 Jun 20;186(12):7016-24. Epub 2011 May 20.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center Rotterdam, Rotterdam 3015 CE, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1003977DOI Listing
June 2011

Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B.

J Hepatol 2011 Feb 6;54(2):209-18. Epub 2010 Sep 6.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2010.07.009DOI Listing
February 2011

Hepatitis B virus lacks immune activating capacity, but actively inhibits plasmacytoid dendritic cell function.

PLoS One 2011 Jan 5;6(1):e15324. Epub 2011 Jan 5.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016396PMC
January 2011

A nonredundant role for canonical NF-κB in human myeloid dendritic cell development and function.

J Immunol 2010 Dec 12;185(12):7252-61. Epub 2010 Nov 12.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1000672DOI Listing
December 2010

Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling.

J Immunol 2010 Jun 19;184(12):6600-11. Epub 2010 May 19.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.0903089DOI Listing
June 2010

The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells.

Virology 2009 Oct 15;393(1):84-90. Epub 2009 Aug 15.

Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.virol.2009.07.015DOI Listing
October 2009

Immunology of hepatitis B and hepatitis C virus infections.

Best Pract Res Clin Gastroenterol 2008 ;22(6):1049-61

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bpg.2008.11.015DOI Listing
April 2009

Modulation of dendritic cell function by persistent viruses.

J Leukoc Biol 2009 Feb 25;85(2):205-14. Epub 2008 Sep 25.

Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0408241DOI Listing
February 2009

Handbook of experimental pharmacology "dendritic cells": the use of dexamethasone in the induction of tolerogenic DCs.

Handb Exp Pharmacol 2009 (188):233-49

Department of Nephrology, Leiden University Medical Center, C3P, Albinusdreef 2, P.O. Box 9600, Leiden, NL-2300RC, The Netherlands.

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http://dx.doi.org/10.1007/978-3-540-71029-5_11DOI Listing
February 2009

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients.

Clin Immunol 2008 Dec 26;129(3):419-27. Epub 2008 Sep 26.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.clim.2008.07.029DOI Listing
December 2008

CD40L stimulation of rat dendritic cells specifically favors the IL-12/IL-10 ratio resulting in a strong T cell stimulatory capacity.

Mol Immunol 2008 May 8;45(9):2641-50. Epub 2008 Feb 8.

Leiden University Medical Center, Department of Nephrology, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2007.12.014DOI Listing
May 2008

Immune modulation of human dendritic cells by complement.

Eur J Immunol 2007 Oct;37(10):2803-11

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/eji.200636845DOI Listing
October 2007

IL-10-producing macrophages preferentially clear early apoptotic cells.

Blood 2006 Jun 23;107(12):4930-7. Epub 2006 Feb 23.

Department of Nephrology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2005-10-4144DOI Listing
June 2006

Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells.

J Immunol 2004 Sep;173(5):3044-50

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.173.5.3044DOI Listing
September 2004

Dendritic cells and complement: at the cross road of innate and adaptive immunity.

Mol Immunol 2004 Jun;41(2-3):133-40

Department of Nephrology, Leiden University Medical Center, C3-P, Albinusdreef 2, P.O. Box 9600, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2004.03.018DOI Listing
June 2004

Maturation of dendritic cells abrogates C1q production in vivo and in vitro.

Blood 2004 May 15;103(10):3813-20. Epub 2004 Jan 15.

Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1182/blood-2003-09-3046DOI Listing
May 2004

Functional modulation of dendritic cells to suppress adaptive immune responses.

J Leukoc Biol 2003 Apr;73(4):428-41

Department of Nephrology, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0902431DOI Listing
April 2003

Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression.

Blood 2003 Feb 26;101(4):1439-45. Epub 2002 Sep 26.

Department of Nephrology, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1182/blood-2002-06-1688DOI Listing
February 2003

Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids.

Br J Pharmacol 2002 Sep;137(2):197-204

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/sj.bjp.0704866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573489PMC
September 2002

Corticosteroids prevent generation of CD34+-derived dermal dendritic cells but do not inhibit Langerhans cell development.

J Immunol 2002 Jun;168(12):6181-8

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.168.12.6181DOI Listing
June 2002

Human immature dendritic cells efficiently bind and take up secretory IgA without the induction of maturation.

J Immunol 2002 Jan;168(1):102-7

Department of Cell Biology and Histology, University of Amsterdam, Amsterdam Medical Center, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.168.1.102DOI Listing
January 2002