Andrea I McClatchey

Andrea I McClatchey

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Andrea I McClatchey

Andrea I McClatchey

Publications by authors named "Andrea I McClatchey"

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44Publications

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Actin' Up to Stop SNFin Out TEAD.

Dev Cell 2018 12;47(6):693-695

MGH Center for Cancer Research and Cutaneous Biology Research Center, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.devcel.2018.11.037DOI Listing
December 2018

Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface.

Genes Dev 2018 09 24;32(17-18):1201-1214. Epub 2018 Aug 24.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.317354.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120716PMC
September 2018

Cell-Cell Contact and Receptor Tyrosine Kinase Signaling.

Cold Spring Harb Perspect Biol 2018 06 1;10(6). Epub 2018 Jun 1.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Departments of Pathology, Charlestown, Massachusetts 02129.

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http://dx.doi.org/10.1101/cshperspect.a029215DOI Listing
June 2018

Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis.

Development 2018 04 30;145(9). Epub 2018 Apr 30.

Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA

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http://dx.doi.org/10.1242/dev.162123DOI Listing
April 2018

EGFR-induced cytoskeletal changes drive complex cell behaviors: The tip of the iceberg.

Sci Signal 2018 01 30;11(515). Epub 2018 Jan 30.

Department of Pathology, Massachusetts General Hospital Center for Cancer Research, Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1126/scisignal.aas9473DOI Listing
January 2018

NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.

J Cell Biol 2015 Oct 19;211(2):391-405. Epub 2015 Oct 19.

Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129 Department of Pathology, Massachusetts General Hospital, Charlestown, MA 02129 Department of Pathology, Harvard Medical School, Boston, MA 02115

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http://dx.doi.org/10.1083/jcb.201503081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621825PMC
October 2015

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.

Cell Rep 2015 Mar 12;10(10):1692-1707. Epub 2015 Mar 12.

Cancer Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565791PMC
March 2015

ERM proteins at a glance.

J Cell Sci 2014 Aug 20;127(Pt 15):3199-204. Epub 2014 Jun 20.

Massachusetts General Hospital Center for Cancer Research, Harvard Medical School Department of Pathology, 149 13th Street, Charlestown, MA 02129, USA

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http://dx.doi.org/10.1242/jcs.098343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117225PMC
August 2014

Ezrin tunes the magnitude of humoral immunity.

J Immunol 2013 Oct 16;191(8):4048-58. Epub 2013 Sep 16.

Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195;

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http://dx.doi.org/10.4049/jimmunol.1301315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808844PMC
October 2013

Merlin/ERM proteins establish cortical asymmetry and centrosome position.

Genes Dev 2012 Dec;26(24):2709-23

Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.194027.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533076PMC
December 2012

Contact inhibition (of proliferation) redux.

Curr Opin Cell Biol 2012 Oct 24;24(5):685-94. Epub 2012 Jul 24.

Massachusetts General Hospital Center for Cancer Research and Harvard Medical School Department of Pathology, Charlestown, MA, USA.

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http://dx.doi.org/10.1016/j.ceb.2012.06.009DOI Listing
October 2012

ERM proteins.

Curr Biol 2012 Sep;22(18):R784-5

MGH Center for Cancer Research and Harvard Medical School, Department of Pathology, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.cub.2012.07.057DOI Listing
September 2012

SPRED proteins provide a NF-ty link to Ras suppression.

Genes Dev 2012 Jul;26(14):1515-9

Massachusetts General Hospital Center for Cancer Research, Department of Pathology, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.197434.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404379PMC
July 2012

Spatial regulation of receptor tyrosine kinases in development and cancer.

Nat Rev Cancer 2012 May 24;12(6):387-400. Epub 2012 May 24.

MGH Center for Cancer Research, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1038/nrc3277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767127PMC
May 2012

Ezrin-mediated apical integrity is required for intestinal homeostasis.

Proc Natl Acad Sci U S A 2011 Jul 5;108(29):11924-9. Epub 2011 Jul 5.

Massachusetts General Hospital Center for Cancer Research and Department of Pathology, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1073/pnas.1103418108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141968PMC
July 2011

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.

Genes Dev 2010 Aug 30;24(16):1718-30. Epub 2010 Jul 30.

Department of Pathology, Massachusetts General Hospital Center for Cancer Research, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1101/gad.1938710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922501PMC
August 2010

Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.

PLoS One 2010 Aug 27;5(8):e12404. Epub 2010 Aug 27.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012404PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929185PMC
August 2010

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

Cancer Res 2010 May 20;70(9):3483-93. Epub 2010 Apr 20.

Department of Radiation Oncology, Steele Laboratory, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785015PMC
May 2010

Organizing the cell cortex: the role of ERM proteins.

Nat Rev Mol Cell Biol 2010 Apr;11(4):276-87

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois 60637, USA.

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http://www.nature.com/articles/nrm2866
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http://dx.doi.org/10.1038/nrm2866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871950PMC
April 2010

Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma.

Proc Natl Acad Sci U S A 2009 Jun 1;106(24):9767-72. Epub 2009 Jun 1.

Massachusetts General Hospital Center for Cancer Research and Department of Pathology, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1073/pnas.0902031106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700996PMC
June 2009

Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.

Trends Cell Biol 2009 May 1;19(5):198-206. Epub 2009 Apr 1.

Massachusetts General Hospital Center for Cancer Research and Harvard Medical School Department of Pathology, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.tcb.2009.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796113PMC
May 2009

The neurofibroma cell of origin: SKPs expand the playing field.

Cell Stem Cell 2009 May;4(5):371-2

Massachusetts General Hospital Center for Cancer Research and Department of Pathology, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.stem.2009.04.010DOI Listing
May 2009

Ezrin and moesin function together to promote T cell activation.

J Immunol 2009 Jan;182(2):1021-32

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491660PMC
http://dx.doi.org/10.4049/jimmunol.182.2.1021DOI Listing
January 2009

Neurofibromatosis.

Annu Rev Pathol 2007 ;2:191-216

Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.pathol.2.01
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http://dx.doi.org/10.1146/annurev.pathol.2.010506.091940DOI Listing
August 2008

Audiologic and radiographic response of NF2-related vestibular schwannoma to erlotinib therapy.

Nat Clin Pract Oncol 2008 Aug 17;5(8):487-91. Epub 2008 Jun 17.

Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Yawkey 9E, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/ncponc1157DOI Listing
August 2008

Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing.

Mol Cell Biol 2008 Feb 17;28(4):1274-84. Epub 2007 Dec 17.

Massachusetts General Hospital East, 149 CNY 13th St., Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1128/MCB.01139-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258752PMC
February 2008

Contact-dependent inhibition of EGFR signaling by Nf2/Merlin.

J Cell Biol 2007 Jun;177(5):893-903

MGH Center for Cancer Research, Harvard Medical School Department of Pathology, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1083/jcb.200703010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064288PMC
June 2007

Microvilli defects in retinas of ezrin knockout mice.

Exp Eye Res 2006 Apr 10;82(4):720-9. Epub 2005 Nov 10.

Department of Ophthalmic Research, The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.exer.2005.09.013DOI Listing
April 2006

Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin.

Genes Dev 2005 Oct;19(19):2265-77

Massachusetts General Hospital, Center for Cancer Research and Harvard Medical School, Department of Pathology, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.1335605DOI Listing
October 2005

A mouse model recapitulating molecular features of human mesothelioma.

Cancer Res 2005 Sep;65(18):8090-5

Human Genetics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2312DOI Listing
September 2005

Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.

Dev Cell 2004 Jun;6(6):855-64

MGH Cancer Center and Harvard Medical School Department of Pathology, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.devcel.2004.05.007DOI Listing
June 2004

Ezrin...a metastatic detERMinant?

Cancer Cell 2004 Feb;5(2):113-4

MGH Cancer Center and Harvard Medical School Department of Pathology, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s1535-6108(04)00031-5DOI Listing
February 2004

Merlin and ERM proteins: unappreciated roles in cancer development?

Nat Rev Cancer 2003 11;3(11):877-83

Massachusetts General Hospital Cancer Center, Harvard Medical School Department of Pathology, 149 13th Street, Charlestown, Massachusetts 02129, USA.

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http://www.nature.com/doifinder/10.1038/nrc1213
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http://dx.doi.org/10.1038/nrc1213DOI Listing
November 2003

NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.

Genes Dev 2003 May 14;17(9):1090-100. Epub 2003 Apr 14.

MGH Cancer Center and Harvard Medical School Department of Pathology, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.1054603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC196046PMC
May 2003

DOCK4, a GTPase activator, is disrupted during tumorigenesis.

Cell 2003 Mar;112(5):673-84

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00155-7DOI Listing
March 2003