Andrea D Eckhart

Andrea D Eckhart

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Andrea D Eckhart

Andrea D Eckhart

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Erratum to: Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism.

J Inherit Metab Dis 2016 09;39(5):757

Department of Molecular and Human Genetics, Medical Genetics Laboratory, Baylor College of Medicine, One Baylor Plaza, NAB2015, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10545-016-9944-yDOI Listing
September 2016

Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism.

J Inherit Metab Dis 2015 Nov 15;38(6):1029-39. Epub 2015 Apr 15.

Department of Molecular and Human Genetics, Medical Genetics Laboratory, Baylor College of Medicine, One Baylor Plaza, NAB2015, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10545-015-9843-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626538PMC
November 2015

Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle.

FASEB J 2014 Feb 16;28(2):956-65. Epub 2013 Oct 16.

2Department of Medicine, Thomas Jefferson University, Room 317, College Bldg., 1025 Walnut St., Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1096/fj.13-240226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898647PMC
February 2014

Metabolomics as a key integrator for "omic" advancement of personalized medicine and future therapies.

Clin Transl Sci 2012 Jun;5(3):285-8

Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2011.00388.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439875PMC
June 2012

The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.

Circ Res 2011 Jan 24;108(1):27-39. Epub 2010 Nov 24.

Center for Molecular and Translational Cardiology (M.V, C.W., N.H., K.S., P.M.), Department of Internal Medicine III (O.J.M, S.S., H.J.H., H.A.K.), Division of Cardiology, INF 350, University of Heidelberg, 69120 Heidelberg, Germany; Institute of Physiology and Pathophysiology (F.W., O.F.) Medical Biophysics, INF 326, University of Heidelberg, 69120 Heidelberg, Germany; George Zallie & Family Laboratory for Cardiovascular Gene Therapy (J.E.R., H.B., W.J.K.), Eugene Feiner Laboratory for Vascular Biology and Thrombosis (A.D.E.), Laboratory for Cardiac Stem Cell and Gene Therapy (G.Q., K.P., P.M.), Center for Translational Medicine, Thomas Jefferson University, 19107 Philadelphia, PA, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.225201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013502PMC
January 2011

Regulation of GPCR signaling in hypertension.

Biochim Biophys Acta 2010 Dec 11;1802(12):1268-75. Epub 2010 Jan 11.

Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.bbadis.2010.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972307PMC
December 2010

Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.

Circ Res 2010 Oct 2;107(9):1140-9. Epub 2010 Sep 2.

George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Center for Translational Medicine, Jefferson Medical College, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.221010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966514PMC
October 2010

Negative regulation of VEGF signaling in human coronary artery endothelial cells by G protein-coupled receptor kinase 5.

Clin Transl Sci 2009 Feb;2(1):57-61

Eugene Feiner Laboratory for Vascular Biology and Thrombosis, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2008.00058.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350797PMC
February 2009

[Activation of sterol regulatory element binding protein and its involvement in endothelial cell migration].

Zhonghua Bing Li Xue Za Zhi 2009 Jan;38(1):50-4

Department of Geriatrics, Qilu Hospital of Shandong University, Jinan 250012, China.

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January 2009

Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction.

Am J Physiol Heart Circ Physiol 2008 Oct 22;295(4):H1695-704. Epub 2008 Aug 22.

Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00564.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593515PMC
October 2008

GPCR signalling in hypertension: role of GRKs.

Clin Sci (Lond) 2008 Aug;115(3):79-89

Eugene Feiner Laboratory for Vascular Biology and Thrombosis, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1042/CS20070442DOI Listing
August 2008

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.

Proc Natl Acad Sci U S A 2008 Aug 18;105(34):12457-62. Epub 2008 Aug 18.

George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1073/pnas.0803153105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527933PMC
August 2008

Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells.

Endocrinology 2008 Jul 20;149(7):3569-75. Epub 2008 Mar 20.

Cardiovascular Research Center and Department of Physiology, Temple University School of Medicine, 3420 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1210/en.2007-1694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453088PMC
July 2008

Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells.

Cardiovasc Res 2008 May 10;78(2):376-84. Epub 2008 Feb 10.

Division of Endocrinology, Diabetes and Metabolic Diseases, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Suite 320, Curtis Building, 1015 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1093/cvr/cvn034DOI Listing
May 2008

Simultaneous administration of insulin-like growth factor-1 and darbepoetin alfa protects the rat myocardium against myocardial infarction and enhances angiogenesis.

Clin Transl Sci 2008 May;1(1):13-20

George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Center for Translational Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2008.00008.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016870PMC
May 2008

Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.

Circulation 2008 Mar 3;117(11):1378-87. Epub 2008 Mar 3.

Center for Translational Medicine and George Zallie and Family Laboratory of Cardiovascular Gene Therapy, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.752618DOI Listing
March 2008

Enhanced sterol response element-binding protein in postintervention restenotic blood vessels plays an important role in vascular smooth muscle proliferation.

Life Sci 2008 Jan 17;82(3-4):174-81. Epub 2007 Nov 17.

Eugene Feiner Laboratory of Vascular Biology and Thrombosis, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002432050700804
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http://dx.doi.org/10.1016/j.lfs.2007.10.025DOI Listing
January 2008

Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension.

Am J Physiol Heart Circ Physiol 2007 Nov 14;293(5):H3072-9. Epub 2007 Sep 14.

Eugene Feiner Laboratory of Vascular Biology and Thrombosis, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1152/ajpheart.00880.2007DOI Listing
November 2007

Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart.

Am J Physiol Heart Circ Physiol 2007 Jul 23;293(1):H60-8. Epub 2007 Mar 23.

Center for Translational Medicine, George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00227.2007DOI Listing
July 2007

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue.

Circulation 2007 May 30;115(19):2506-15. Epub 2007 Apr 30.

Center for Translational Medicine and George Zallie and Family Laboratory of Cardiovascular Gene Therapy, Thomas Jefferson University, 1025 Walnut St, Room 317, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.671701DOI Listing
May 2007

Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure.

Nat Med 2007 Mar 18;13(3):315-23. Epub 2007 Feb 18.

Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1038/nm1553DOI Listing
March 2007

Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq.

Cell Signal 2006 Oct 28;18(10):1695-701. Epub 2006 Feb 28.

Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.cellsig.2006.01.009DOI Listing
October 2006

Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction.

Circulation 2006 Sep 4;114(12):1258-68. Epub 2006 Sep 4.

Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.622415DOI Listing
September 2006

Galphaq and its Aktions.

J Mol Cell Cardiol 2006 May 21;40(5):589-92. Epub 2006 Apr 21.

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http://dx.doi.org/10.1016/j.yjmcc.2006.03.001DOI Listing
May 2006

S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction.

Mol Ther 2005 Dec 15;12(6):1120-9. Epub 2005 Sep 15.

Medizinische Universitätsklinik und Poliklinik III, Otto Meyerhof Zentrum, Universität zu Heidelberg, INF 350, 69115 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ymthe.2005.08.002DOI Listing
December 2005

Acute ischemic cardiac dysfunction is attenuated via gene transfer of a peptide inhibitor of the beta-adrenergic receptor kinase (betaARK1).

J Gene Med 2005 Sep;7(9):1172-7

Department of Cardiovascular Surgery, University Hospital, Bern, Switzerland.

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http://dx.doi.org/10.1002/jgm.770DOI Listing
September 2005

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium.

J Clin Invest 2004 Dec;114(11):1550-63

Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1172/JCI21454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC529280PMC
December 2004

Heterotopic transplantation as a model to study functional recovery of unloaded failing hearts.

J Thorac Cardiovasc Surg 2002 Dec;124(6):1149-56

Departments of Surgery and Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1067/mtc.2002.127315DOI Listing
December 2002

Gq-coupled receptor agonists mediate cardiac hypertrophy via the vasculature.

Hypertension 2002 Nov;40(5):660-6

Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

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November 2002

Donor heart contractile dysfunction following prolonged ex vivo preservation can be prevented by gene-mediated beta-adrenergic signaling modulation.

Eur J Cardiothorac Surg 2002 Nov;22(5):733-7

Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

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November 2002

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.

J Biol Chem 2002 Aug 4;277(35):32116-23. Epub 2002 Jun 4.

Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M204895200DOI Listing
August 2002

Myocardial gene transfer and overexpression of beta2-adrenergic receptors potentiates the functional recovery of unloaded failing hearts.

Circulation 2002 Jul;106(1):124-9

Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

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July 2002

Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure.

Mol Pharmacol 2002 Apr;61(4):749-58

Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

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April 2002

Expression of a beta-adrenergic receptor kinase inhibitor reverses dysfunction in failing cardiomyocytes.

Mol Ther 2002 Jan;5(1):74-9

Departments of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1006/mthe.2001.0508DOI Listing
January 2002

Beta-Adrenergic gene therapy for cardiovascular disease.

Curr Control Trials Cardiovasc Med 2000 ;1(3):131-134

Duke University Medical Center, Durham, North Carolina, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC59618PMC
http://dx.doi.org/10.1186/cvm-1-3-131DOI Listing
January 2000