Publications by authors named "Andrea Bild"

57Publications

Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model.

Cancer Cell Int 2020 17;20:253. Epub 2020 Jun 17.

Department of Medical Oncology and Therapeutics Research, Beckman Research Institute, City of Hope National Medical Center, 1218 S Fifth Ave, Monrovia, CA 91016 USA.

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http://dx.doi.org/10.1186/s12935-020-01337-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301982PMC
June 2020

Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors.

Lung Cancer 2020 08 24;146:174-181. Epub 2020 May 24.

Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA, USA; Division of Medical Oncology, Cedars-Sinai Medical Center, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.05.025DOI Listing
August 2020

Opportunities for improving cancer treatment using systems biology.

Curr Opin Syst Biol 2019 Oct 27;17:41-50. Epub 2019 Nov 27.

Department of Medical Oncology, Division of Molecular Pharmacology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.coisb.2019.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282416PMC
October 2019

Pathway activity profiling of growth factor receptor network and stemness pathways differentiates metaplastic breast cancer histological subtypes.

BMC Cancer 2019 Sep 5;19(1):881. Epub 2019 Sep 5.

Department of Medical Oncology and Therapeutics Research, City of Hope, 1218 S Fifth Ave, Monrovia, CA, 91016, USA.

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http://dx.doi.org/10.1186/s12885-019-6052-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727561PMC
September 2019

Engineered 3D Model of Cancer Stem Cell Enrichment and Chemoresistance.

Neoplasia 2019 08 9;21(8):822-836. Epub 2019 Jul 9.

Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Macromolecular Science and Engineering, University of Michigan, Ann Arbor, MI, USA.. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624324PMC
August 2019

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.

Cell Rep 2019 03;26(11):3061-3075.e6

Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Division of Gynecology-Oncology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA; Division of Hematology-Oncology, Department of Internal Medicine, Division of Gynecology-Oncology, Department of Obstetrics and Gynecology, and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA; Magee-Womens Research Institute, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061440PMC
March 2019

Enhanced Kat3A/Catenin transcription: a common mechanism of therapeutic resistance.

Cancer Drug Resist 2019 19;2:917-932. Epub 2019 Sep 19.

Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.20517/cdr.2019.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234864PMC
September 2019

Mechanisms and clinical implications of tumor heterogeneity and convergence on recurrent phenotypes.

J Mol Med (Berl) 2017 11 4;95(11):1167-1178. Epub 2017 Sep 4.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1007/s00109-017-1587-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296823PMC
November 2017

Window-of-Opportunity Study of Valproic Acid in Breast Cancer Testing a Gene Expression Biomarker.

JCO Precis Oncol 2017 7;1. Epub 2017 Apr 7.

, , , , , , , , and , University of Utah; , , , , and , Huntsman Cancer Institute, Salt Lake City; , Brigham Young University, Provo, UT; , University of Arizona, Tucson, AZ; and , Advanced Imaging Research Center, Portland, OR.

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http://dx.doi.org/10.1200/PO.16.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446454PMC
April 2017

The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers.

Semin Cell Dev Biol 2016 10 20;58:108-17. Epub 2016 Jun 20.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, USA; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2016.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951171PMC
October 2016

Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility.

Mol Syst Biol 2016 Mar 10;12(3):860. Epub 2016 Mar 10.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, USA Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812528PMC
http://dx.doi.org/10.15252/msb.20156506DOI Listing
March 2016

Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility.

BMC Med Genomics 2015 Nov 4;8:72. Epub 2015 Nov 4.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1186/s12920-015-0145-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634735PMC
November 2015

Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results.

Bioinformatics 2015 Nov 24;31(22):3666-72. Epub 2015 Jul 24.

Department of Biology, Brigham Young University, Provo, UT 84604, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804769PMC
November 2015

Inferring pathway dysregulation in cancers from multiple types of omic data.

Genome Med 2015 26;7(1):61. Epub 2015 Jun 26.

Department of Oncological Sciences, University of Utah, Salt Lake City, UT USA ; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT USA.

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http://dx.doi.org/10.1186/s13073-015-0189-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499940PMC
July 2015

ASSIGN: context-specific genomic profiling of multiple heterogeneous biological pathways.

Bioinformatics 2015 Jun 22;31(11):1745-53. Epub 2015 Jan 22.

Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA 02118 USA, Department of Biomedical Informatics and Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112 USA Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA 02118 USA, Department of Biomedical Informatics and Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112 USA.

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http://dx.doi.org/10.1093/bioinformatics/btv031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443674PMC
June 2015

Genomic classification of the RAS network identifies a personalized treatment strategy for lung cancer.

Mol Oncol 2014 Oct 20;8(7):1339-54. Epub 2014 May 20.

Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

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http://doi.wiley.com/10.1016/j.molonc.2014.05.005
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http://dx.doi.org/10.1016/j.molonc.2014.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450766PMC
October 2014

A field guide to genomics research.

PLoS Biol 2014 Jan 7;12(1):e1001744. Epub 2014 Jan 7.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, United States of America ; Division of Computational Biomedicine, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883637PMC
January 2014

Multiplatform single-sample estimates of transcriptional activation.

Proc Natl Acad Sci U S A 2013 Oct 15;110(44):17778-83. Epub 2013 Oct 15.

Departments of Pharmacology and Toxicology, and Oncological Sciences, The University of Utah, Salt Lake City, UT 84112.

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http://dx.doi.org/10.1073/pnas.1305823110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816418PMC
October 2013

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue.

Cancer Res 2012 Nov 17;72(22):5702-11. Epub 2012 Sep 17.

Section of Computational Biomedicine, Department of Medicine, Boston University Medical Center; Bioinformatics Program, Boston University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053174PMC
November 2012

A single-sample microarray normalization method to facilitate personalized-medicine workflows.

Genomics 2012 Dec 19;100(6):337-44. Epub 2012 Aug 19.

Department of Pharmacology and Toxicology, University of Utah, 201 Presidents Circle, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.ygeno.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508193PMC
December 2012

Major differences among chemopreventive organoselenocompounds in the sustained elevation of cytoprotective genes.

J Biochem Mol Toxicol 2012 Sep 16;26(9):344-53. Epub 2012 Jul 16.

Department of Pharmacology and Toxicology, University of Utah College of Pharmacy, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1002/jbt.21427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551423PMC
September 2012

A pharmacogenomic method for individualized prediction of drug sensitivity.

Mol Syst Biol 2011 Jul 19;7:513. Epub 2011 Jul 19.

Division of Internal Medicine, Department of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1038/msb.2011.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159972PMC
July 2011

Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.

Cancer Res 2008 Oct;68(20):8525-34

Department of Molecular Genetics and Microbiology, Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617051PMC
October 2008

Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies.

Curr Oncol Rep 2006 Jul;8(4):252-7

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27708, USA.

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http://dx.doi.org/10.1007/s11912-006-0029-1DOI Listing
July 2006

Genomic signatures to guide the use of chemotherapeutics.

Nat Med 2006 Nov 22;12(11):1294-300. Epub 2006 Oct 22.

Duke Institute for Genome Sciences and Policy, Duke University, Box 3382, Durham, North Carolina 27710, USA.

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http://www.nature.com/articles/nm1491
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http://dx.doi.org/10.1038/nm1491DOI Listing
November 2006

Linking oncogenic pathways with therapeutic opportunities.

Nat Rev Cancer 2006 09 17;6(9):735-41. Epub 2006 Aug 17.

Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nrc1976DOI Listing
September 2006

Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.

Clin Cancer Res 2006 Feb;12(3 Pt 1):819-26

Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-1447DOI Listing
February 2006

Oncogenic pathway signatures in human cancers as a guide to targeted therapies.

Nature 2006 Jan 6;439(7074):353-7. Epub 2005 Nov 6.

Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1038/nature04296DOI Listing
January 2006

Gene-expression patterns predict phenotypes of immune-mediated thrombosis.

Blood 2006 Feb 1;107(4):1391-6. Epub 2005 Nov 1.

Department of Medicine, Duke University Medical Center, Box 3841 Red Zone, Durham, NC 27710, USA.

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http://dx.doi.org/10.1182/blood-2005-07-2669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895419PMC
February 2006

Application of a priori established gene sets to discover biologically important differential expression in microarray data.

Proc Natl Acad Sci U S A 2005 Oct 17;102(43):15278-9. Epub 2005 Oct 17.

Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0507477102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266131PMC
October 2005

DIG--a system for gene annotation and functional discovery.

Bioinformatics 2005 Jul 3;21(13):2957-9. Epub 2005 May 3.

Duke Institute for Genome Sciences and Policy, Duke University Medical Center Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/bioinformatics/bti467DOI Listing
July 2005

Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes.

Proc Natl Acad Sci U S A 2004 Jun 19;101(22):8431-6. Epub 2004 May 19.

Institute of Statistics and Decision Sciences, Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0401736101
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http://dx.doi.org/10.1073/pnas.0401736101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420411PMC
June 2004

Gene expression phenotypic models that predict the activity of oncogenic pathways.

Nat Genet 2003 Jun;34(2):226-30

Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/ng1167DOI Listing
June 2003

MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.

Oncogene 2002 Sep;21(43):6649-56

Department of Pharmacology, University of Colorado, 2400 East Ninth Street, Denver, Colorado, CO 80262, USA.

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http://dx.doi.org/10.1038/sj.onc.1205819DOI Listing
September 2002

Cytoplasmic transport of Stat3 by receptor-mediated endocytosis.

EMBO J 2002 Jul;21(13):3255-63

Department of Pharmacology, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA.

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http://emboj.embopress.org/cgi/doi/10.1093/emboj/cdf351
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http://dx.doi.org/10.1093/emboj/cdf351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126099PMC
July 2002