Publications by authors named "Andre Marette"

100Publications

Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr/ApoB/IGF-II mice.

Exp Gerontol 2020 Oct 27;140:111075. Epub 2020 Aug 27.

Institut Universitaire de Cardiologie et de Pneumologie de Québec/Québec Heart & Lung Institute, Laval University, Québec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2020.111075DOI Listing
October 2020

Gut microbiota impairs insulin clearance in obese mice.

Mol Metab 2020 Aug 26:101067. Epub 2020 Aug 26.

Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute McMaster University, Hamilton, ON, Canada, L8N 3Z5. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2020.101067DOI Listing
August 2020

Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity.

Nutrients 2020 Jul 30;12(8). Epub 2020 Jul 30.

Quebec Heart and Lung Institute Research Centre, Faculty of Medicine, Laval University, Quebec City, QC G1V 0A6 G1V 4G5, Canada.

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http://dx.doi.org/10.3390/nu12082292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469035PMC
July 2020

Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLrApoB mice.

Atherosclerosis 2020 07 24;304:9-21. Epub 2020 May 24.

Quebec Heart and Lung Institute, Department of Medicine, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada; Institute of Nutraceuticals and Functional Foods, Laval University, Quebec City, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.05.002DOI Listing
July 2020

Potential therapeutic applications of the gut microbiome in obesity: from brain function to body detoxification.

Int J Obes (Lond) 2020 Sep 10;44(9):1818-1831. Epub 2020 Jun 10.

Quebec Heart and Lung Institute, and Department of Medicine, Université Laval, Québec, QC, Canada.

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http://dx.doi.org/10.1038/s41366-020-0618-3DOI Listing
September 2020

Microbial translocation in type 2 diabetes: when bacterial invaders overcome host defence in human obesity.

Gut 2020 Oct 9;69(10):1724-1726. Epub 2020 Jun 9.

Department of Medicine, Universite Laval Faculte de medecine, Quebec, Quebec, Canada

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http://dx.doi.org/10.1136/gutjnl-2020-321288DOI Listing
October 2020

The Bacterium : A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation.

Front Immunol 2020 9;11:645. Epub 2020 Apr 9.

Infectious Diseases and Immunity in Global Health Program, Research Institute, McGill University Health Centre, Montréal, QC, Canada.

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http://dx.doi.org/10.3389/fimmu.2020.00645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160922PMC
April 2020

Blueberry proanthocyanidins and anthocyanins improve metabolic health through a gut microbiota-dependent mechanism in diet-induced obese mice.

Am J Physiol Endocrinol Metab 2020 Jun 31;318(6):E965-E980. Epub 2020 Mar 31.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Hôpital Laval, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1152/ajpendo.00560.2019DOI Listing
June 2020

Metformin effect on gut microbiota: insights for HIV-related inflammation.

AIDS Res Ther 2020 03 10;17(1):10. Epub 2020 Mar 10.

Infectious Diseases and Immunity in Global Health Program, Research Institute, McGill University Health Centre, 1001 Blvd Décarie, Montréal, QC, Canada.

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http://dx.doi.org/10.1186/s12981-020-00267-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063824PMC
March 2020

The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.

Mol Metab 2019 12 4;30:184-191. Epub 2019 Oct 4.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval (CRIUCPQ), Québec City, Québec, Canada; Département de Médecine de l'Université Laval, Université Laval, Québec City, Québec, Canada; Centre de Recherche sur le Cancer de l'Université Laval, Université Laval, Québec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889588PMC
December 2019

Maternal folic acid supplementation does not counteract the deleterious impact of prenatal exposure to environmental pollutants on lipid homeostasis in male rat descendants.

J Dev Orig Health Dis 2019 Sep 16:1-11. Epub 2019 Sep 16.

School of Nutrition, Faculty of Agricultural and Food Sciences, Centre de recherche en reproduction, développement et santé intergénérationnelle, Université Laval, Quebec City, QC, Canada.

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http://dx.doi.org/10.1017/S2040174419000497DOI Listing
September 2019

Identification of A Novel Antibacterial Peptide from Atlantic Mackerel belonging to the GAPDH-Related Antimicrobial Family and Its In Vitro Digestibility.

Mar Drugs 2019 Jul 12;17(7). Epub 2019 Jul 12.

Institute of Nutrition and Functional Foods (INAF), Université Laval, Québec, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/md17070413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669513PMC
July 2019

Bacteria to alleviate metabolic syndrome.

Nat Med 2019 07;25(7):1031-1033

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute and Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada.

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http://dx.doi.org/10.1038/s41591-019-0516-1DOI Listing
July 2019

Alterations of Gut Microbiota After Biliopancreatic Diversion with Duodenal Switch in Wistar Rats.

Obes Surg 2019 09;29(9):2831-2842

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Pavillon Marguerite-d'Youville 2725 chemin Sainte- Foy, Québec, G1V 4G5, Canada.

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http://dx.doi.org/10.1007/s11695-019-03911-7DOI Listing
September 2019

Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.

Circ Res 2019 08 3;125(4):449-466. Epub 2019 Jun 3.

From the Pulmonary Hypertension Research Group of the Institut Universitaire de Cardiologie et de Pneumologie de Québec Research Center, Laval University, Québec City, Canada (B.R., V.N., A.B., S.P., E.T., J.O., N.C., R.A-A., L.T., A.D., S.B.-B., P.P., R.P., O.B., S.B., F.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314555DOI Listing
August 2019

How Charge and Triple Size-Selective Membrane Separation of Peptides from Salmon Protein Hydrolysate Orientate their Biological Response on Glucose Uptake.

Int J Mol Sci 2019 Apr 20;20(8). Epub 2019 Apr 20.

Department of Food Sciences and Laboratory of Food Processing and Electromembrane Processes (LTAPEM), Université Laval, Quebec, QC G1V 0A6, Canada.

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http://dx.doi.org/10.3390/ijms20081939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515250PMC
April 2019

Reprint of "Postprandial lipemia and fecal fat excretion in rats is affected by the calcium content and type of milk fat present in Cheddar-type cheeses".

Food Res Int 2019 04 1;118:65-71. Epub 2018 Nov 1.

Research and Development Centre, Agriculture and Agri-Food Canada, 3600 Casavant Boulevard West, J2S 8E3 Saint-Hyacinthe, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.foodres.2018.10.089DOI Listing
April 2019

Total Synthesis of the Antidiabetic (Type 2) Lipid Mediator Protectin DX/PDX.

J Org Chem 2019 01 26;84(2):495-505. Epub 2018 Dec 26.

Department of Medicine , Québec Heart and Lung Institute , Laval Hospital, Québec , QC G1V 4G5 , Canada.

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http://dx.doi.org/10.1021/acs.joc.8b01973DOI Listing
January 2019

Characterization and visualization of the liposecretion process taking place during ceiling culture of human mature adipocytes.

J Cell Physiol 2019 07 18;234(7):10270-10280. Epub 2018 Dec 18.

Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Québec, Québec, Canada.

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http://dx.doi.org/10.1002/jcp.27931DOI Listing
July 2019

Novel perspectives on fermented milks and cardiometabolic health with a focus on type 2 diabetes.

Nutr Rev 2018 12;76(Suppl 1):16-28

Heart and Lung Institute of Quebec and the Institute of Nutrition and Functional Foods, Laval University, Quebec, Canada.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/nutrit/nuy060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280950PMC
December 2018

Activated platelets promote an osteogenic programme and the progression of calcific aortic valve stenosis.

Eur Heart J 2019 05;40(17):1362-1373

Laboratory of Cardiovascular Pathobiology, Department of Surgery, Quebec Heart and Lung Institute/Research Center, Laval University, 2725 chemin Ste-Foy, Quebec, Canada.

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http://dx.doi.org/10.1093/eurheartj/ehy696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492053PMC
May 2019

Cytokines promote lipolysis in 3T3-L1 adipocytes through induction of NADPH oxidase 3 expression and superoxide production.

J Lipid Res 2018 12 12;59(12):2321-2328. Epub 2018 Oct 12.

Department of Medicine, Cardiology Axis of the Quebec Heart and Lung Research Institute, Laval University, Quebec, QC, Canada

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http://www.jlr.org/lookup/doi/10.1194/jlr.M086504
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http://dx.doi.org/10.1194/jlr.M086504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277153PMC
December 2018

Treatment with camu camu () prevents obesity by altering the gut microbiota and increasing energy expenditure in diet-induced obese mice.

Gut 2019 03 31;68(3):453-464. Epub 2018 Jul 31.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Québec, Canada.

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http://dx.doi.org/10.1136/gutjnl-2017-315565DOI Listing
March 2019

Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.

Brain Behav Immun 2018 10 15;73:450-469. Epub 2018 Jun 15.

Axe neurosciences, Centre de recherche du CHU de Québec, Centre Hospitalier de l'Université Laval (CHUL), 2705 Laurier Blvd., Québec City, Québec G1V 4G2, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08891591183022
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http://dx.doi.org/10.1016/j.bbi.2018.06.007DOI Listing
October 2018

Apple peel polyphenols reduce mitochondrial dysfunction in mice with DSS-induced ulcerative colitis.

J Nutr Biochem 2018 07 21;57:56-66. Epub 2018 Mar 21.

Research Centre, CHU Sainte-Justine, Université de Montréal, Montreal, Quebec, Canada, H3T 1C5; Department of Nutrition, Université de Montréal, Montreal, Quebec, Canada, H3T 1C5; Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada, G1V 0A6; Department of Anatomy and Cellular Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada, J1H 5N4. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2018.03.008DOI Listing
July 2018

Hypertriglyceridemic Waist: A Simple Marker of High-Risk Atherosclerosis Features Associated With Excess Visceral Adiposity/Ectopic Fat.

J Am Heart Assoc 2018 04 13;7(8). Epub 2018 Apr 13.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Québec, Canada

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http://dx.doi.org/10.1161/JAHA.117.008139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015425PMC
April 2018

Postprandial lipemia and fecal fat excretion in rats is affected by the calcium content and type of milk fat present in Cheddar-type cheeses.

Food Res Int 2018 05 27;107:589-595. Epub 2018 Feb 27.

Research and Development Centre, Agriculture and Agri-Food Canada, 3600 Casavant Boulevard West, J2S 8E3 Saint-Hyacinthe, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.foodres.2018.02.058DOI Listing
May 2018

Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.

FASEB J 2018 07 8;32(7):3623-3640. Epub 2018 Feb 8.

Centre de Recherche du Centre Hospitalier de l'Université (CHU) de Québec, Faculté de Médecine, Université Laval, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1096/fj.201701176RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998970PMC
July 2018

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis in diet-induced obese mice.

Diabetologia 2018 04 21;61(4):919-931. Epub 2017 Dec 21.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Bureau Y4340, Québec City, QC, G1V 4G5, Canada.

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http://dx.doi.org/10.1007/s00125-017-4520-zDOI Listing
April 2018

AMPK in skeletal muscle function and metabolism.

FASEB J 2018 04 5;32(4):1741-1777. Epub 2018 Jan 5.

Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1096/fj.201700442RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945561PMC
April 2018

Yogurt and Cardiometabolic Diseases: A Critical Review of Potential Mechanisms.

Adv Nutr 2017 Nov 15;8(6):812-829. Epub 2017 Nov 15.

Heart and Lung Institute of Quebec, Laval University, Quebec, Canada.

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http://dx.doi.org/10.3945/an.116.013946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682997PMC
November 2017

A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss.

Mol Metab 2017 12 18;6(12):1563-1573. Epub 2017 Oct 18.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699918PMC
December 2017

Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western diet.

Prog Neuropsychopharmacol Biol Psychiatry 2017 10 3;79(Pt B):452-461. Epub 2017 Aug 3.

Université Laval, Faculté de médecine, Département de Psychiatrie et Neurosciences, Québec, Canada; Centre de Recherche du CHU de Québec, Axe Neurosciences, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2017.08.001DOI Listing
October 2017

The Gut Microbiota as a Mediator of Metabolic Benefits after Bariatric Surgery.

Can J Diabetes 2017 Aug 25;41(4):439-447. Epub 2017 May 25.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Quebec City, Quebec, Canada; Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcjd.2017.02.002DOI Listing
August 2017

Hepatocyte SHP-1 is a Critical Modulator of Inflammation During Endotoxemia.

Sci Rep 2017 05 22;7(1):2218. Epub 2017 May 22.

Department of Medicine, Microbiology and Immunology, Faculty of Medicine, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1038/s41598-017-02512-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440389PMC
May 2017

OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway.

Cardiovasc Res 2017 Sep;113(11):1351-1363

Laboratory of Cardiovascular Pathobiology, Institut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Research Center, Department of Surgery, Laval University, 2725 Chemin Ste-Foy, Quebec, Quebec G1V-4G5, Canada.

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http://dx.doi.org/10.1093/cvr/cvx089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852522PMC
September 2017

Loss of hepatic DEPTOR alters the metabolic transition to fasting.

Mol Metab 2017 05 17;6(5):447-458. Epub 2017 Feb 17.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Faculté de Médecine, Université Laval, 2725 Chemin Ste-Foy, Québec, Qc, G1V 4G5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404102PMC
May 2017

Mortality in the Familial Atherosclerosis Treatment Study-Observational Study.

J Clin Lipidol 2017 Jan - Feb;11(1):309-310. Epub 2017 Jan 23.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada; Department of Medicine, Faculty of Medicine, Université Laval, Québec, Canada.

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http://dx.doi.org/10.1016/j.jacl.2017.01.008DOI Listing
October 2018

Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties.

Adv Nutr 2017 Jan 17;8(1):155S-164S. Epub 2017 Jan 17.

Quebec Heart and Lung Institute, Quebec, Canada;

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http://dx.doi.org/10.3945/an.115.011114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227968PMC
January 2017

A microbial protein that alleviates metabolic syndrome.

Nat Med 2017 01;23(1):11-12

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Québec, Canada, and the Institute of Nutrition and Functional Foods, Laval University, Québec, Canada.

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http://dx.doi.org/10.1038/nm.4261DOI Listing
January 2017

Impact of a 1-year lifestyle modification program on plasma lipoprotein and PCSK9 concentrations in patients with coronary artery disease.

J Clin Lipidol 2016 Nov - Dec;10(6):1353-1361. Epub 2016 Sep 2.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Quebec City, Québec, Canada; Department of medicine, Faculty of Medicine, Université Laval, Quebec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2016.08.014DOI Listing
October 2017

Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease.

Neurobiol Dis 2017 Feb 26;98:1-8. Epub 2016 Oct 26.

Université Laval, Faculté de Médecine, Département de Psychiatrie et Neurosciences, Québec, QC, Canada; Centre de recherche du Centre Hospitalier de l'Université Laval de Québec, Axe Neurosciences, Québec, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2016.10.004DOI Listing
February 2017

Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells.

J Cell Biochem 2017 05 10;118(5):1216-1226. Epub 2017 Jan 10.

Laboratório de Oncobiologia Molecular (LabOMol), Departamento de Biotecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-902, Brazil.

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http://dx.doi.org/10.1002/jcb.25774DOI Listing
May 2017

High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology.

Neurobiol Aging 2016 11 29;47:71-73. Epub 2016 Jul 29.

Université Laval, Faculté de médecine, Département de Psychiatrie et Neurosciences, Québec, Quebec, Canada; Centre de Recherche du CHU de Québec, Axe Neurosciences, Québec, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.016DOI Listing
November 2016

G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle.

Mol Metab 2016 Jul 22;5(7):527-537. Epub 2016 Apr 22.

INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France; University of Toulouse, Paul Sabatier University, France. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921782PMC
July 2016

Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease.

Neurobiol Aging 2016 07 30;43:47-57. Epub 2016 Mar 30.

Faculté de pharmacie, Université Laval, Québec, Québec, Canada; Axe Neurosciences, Centre de recherche du CHU-Q (Pavillon CHUL), Québec, Québec, Canada; Institut sur la nutrition et les aliments fonctionnels, Université Laval, Québec, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.024DOI Listing
July 2016

Triggering Akkermansia with dietary polyphenols: A new weapon to combat the metabolic syndrome?

Gut Microbes 2016 ;7(2):146-53

a Department of Medicine ; Faculty of Medicine; Cardiology Axis of the Québec Heart and Lung Institute ; Québec , Canada.

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http://dx.doi.org/10.1080/19490976.2016.1142036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856456PMC
December 2016

Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice.

Neurobiol Dis 2016 Apr 9;88:55-65. Epub 2016 Jan 9.

Université Laval, Faculté de Médecine, Département de Psychiatrie et Neurosciences, Québec, QC, Canada; Centre de recherche du Centre Hospitalier de l'Université Laval de Québec, Axe Neurosciences, Québec, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2016.01.005DOI Listing
April 2016

Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.

Diabetologia 2016 Mar 5;59(3):592-603. Epub 2016 Jan 5.

Department of Medicine, Quebec Heart and Lung Institute, Hôpital Laval, Pavillon Marguerite d'Youville, Room Y4308, 2705 Chemin Ste-Foy, Québec, Canada, G1V 4G5.

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http://dx.doi.org/10.1007/s00125-015-3839-6DOI Listing
March 2016

SCFAs Take a Toll En Route to Metabolic Syndrome.

Cell Metab 2015 Dec;22(6):954-6

Department of Medicine, University of Florida, Gainesville, FL 32611, USA; Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL 32611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.11.006DOI Listing
December 2015

Erratum: Figure Correction: Probiotics as Complementary Treatment for Metabolic Disorders.

Diabetes Metab J 2015 Oct 22;39(5):448-9. Epub 2015 Oct 22.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Québec, QC, Canada. ; Institute of Nutrition and Functional Foods, Laval University, Québec, QC, Canada.

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http://dx.doi.org/10.4093/dmj.2015.39.5.448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641977PMC
October 2015

Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.

Exp Gerontol 2015 Dec 29;72:192-203. Epub 2015 Oct 29.

Centre de recherche du CHU de Québec, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2015.10.012DOI Listing
December 2015

Gut Microbiota Dysbiosis in Obesity-Linked Metabolic Diseases and Prebiotic Potential of Polyphenol-Rich Extracts.

Curr Obes Rep 2015 Dec;4(4):389-400

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Quebec, Canada.

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http://link.springer.com/10.1007/s13679-015-0172-9
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http://dx.doi.org/10.1007/s13679-015-0172-9DOI Listing
December 2015

Vitamin D reduces LPS-induced cytokine release in omental adipose tissue of women but not men.

Steroids 2015 Dec 28;104:65-71. Epub 2015 Aug 28.

Department of Medicine, Laval University, 1050, de la Médecine avenue, Québec G1V 0A6, Canada; Endocrinology and Nephrology Unit, CHU de Québec Research Centre, 2705, Laurier Boulevard, Québec G1V 4G2, Canada; Institute of Nutrition and Functional Foods, 2440, Hochelaga Boulevard, Québec G1V 0A6, Canada. Electronic address:

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December 2015

Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk.

Am J Physiol Endocrinol Metab 2015 Oct 25;309(8):E736-46. Epub 2015 Aug 25.

Endocrinology and Nephrology, Centre Hospitalier Universitaire de Quebec, Quebec City, Canada; School of Nutrition, Laval University, Quebec City, Canada; Quebec Heart and Lung Institute, Quebec City, Canada;

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http://dx.doi.org/10.1152/ajpendo.00231.2015DOI Listing
October 2015

Probiotics as Complementary Treatment for Metabolic Disorders.

Diabetes Metab J 2015 Aug;39(4):291-303

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Québec, QC, Canada. ; Institute of Nutrition and Functional Foods, Laval University, Québec, QC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543192PMC
August 2015

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve.

Circulation 2015 Aug 29;132(8):677-90. Epub 2015 Jul 29.

From Laboratoire d'Études Moléculaires des Valvulopathies (LEMV), Groupe de Recherche en Valvulopathies (GRV), Quebec Heart and Lung Institute/Research Center, Department of Surgery (R.B., A.M., M.J.N., M.-C.B., J.-L.L., M.-H.L., F.H., P.M.), Department of Medicine (A.D., P.P., B.J.A., A.M.), Department of Pathology (C.C., S.T., S.P.), and Department of Molecular Medicine (Y.B.), Laval University, Québec, Canada; and Department of Chemistry and Biochemistry, University of Windsor, Ontario, Canada (C.A.S., R.R., M.L.K.).

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August 2015

Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer's disease.

FASEB J 2015 Oct 24;29(10):4273-84. Epub 2015 Jun 24.

*Faculté de Pharmacie, Institut des Nutraceutiques et des Aliments Fonctionnels, and Département de Medicine, Axe de Cardiologie, Faculté de Médicine, Université Laval, Québec, Québec, Canada; Axe Neurosciences, Centre de Recherche du Centre Hospitalier de l'Université Laval (CHUL), Québec, Québec, Canada; Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Durham, North Carolina, USA; and Institut Universitaire de Pneumologie et de Cardiologie, Québec, Québec, Canada.

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October 2015

Adipose tissue and sustainable development: a connection that needs protection.

Front Pharmacol 2015 27;6:110. Epub 2015 May 27.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec Quebec City, QC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445306PMC
June 2015

Irisin is more strongly predicted by muscle oxidative potential than adiposity in non-diabetic men.

J Physiol Biochem 2015 Sep 28;71(3):559-68. Epub 2015 Mar 28.

Department of Kinesiology, Université Laval, Québec, QC, Canada.

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September 2015

Carbonic anhydrase XII in valve interstitial cells promotes the regression of calcific aortic valve stenosis.

J Mol Cell Cardiol 2015 May 11;82:104-15. Epub 2015 Mar 11.

Laboratoire d'Études Moléculaires des Valvulopathies (LEMV), Groupe de Recherche en Valvulopathies (GRV), Quebec Heart and Lung Institute/Research Center, Department of Surgery, Laval University, Québec, Canada. Electronic address:

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May 2015

Transgenic ω-3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins.

Metabolism 2015 Jun 3;64(6):666-76. Epub 2015 Feb 3.

Department of Medicine, Québec Heart and Lung Institute, Université Laval, Ste-Foy, Québec, Canada and Laval University Hospital Research Center, Metabolism, Vascular and Renal Health Axis, Ste-Foy, Québec, Canada. Electronic address:

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June 2015

Genetic studies of body mass index yield new insights for obesity biology.

Authors:
Adam E Locke Bratati Kahali Sonja I Berndt Anne E Justice Tune H Pers Felix R Day Corey Powell Sailaja Vedantam Martin L Buchkovich Jian Yang Damien C Croteau-Chonka Tonu Esko Tove Fall Teresa Ferreira Stefan Gustafsson Zoltán Kutalik Jian'an Luan Reedik Mägi Joshua C Randall Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Jessica D Faul Jennifer A Smith Jing Hua Zhao Wei Zhao Jin Chen Rudolf Fehrmann Åsa K Hedman Juha Karjalainen Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bolton Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Guohong Deng Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Anuj Goel Jian Gong Anne U Jackson Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Sarah E Medland Michael A Nalls Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Dmitry Shungin Alena Stančáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Aaron Isaacs Eva Albrecht Johan Ärnlöv Gillian M Arscott Antony P Attwood Stefania Bandinelli Amy Barrett Isabelita N Bas Claire Bellis Amanda J Bennett Christian Berne Roza Blagieva Matthias Blüher Stefan Böhringer Lori L Bonnycastle Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Ida H Caspersen Yii-Der Ida Chen Robert Clarke E Warwick Daw Anton J M de Craen Graciela Delgado Maria Dimitriou Alex S F Doney Niina Eklund Karol Estrada Elodie Eury Lasse Folkersen Ross M Fraser Melissa E Garcia Frank Geller Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Alison H Goodall Scott D Gordon Mathias Gorski Hans-Jörgen Grabe Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Christopher J Groves Gaëlle Gusto Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Christian Hengstenberg Oddgeir Holmen Jouke-Jan Hottenga Alan L James Janina M Jeff Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Leena Kinnunen Wolfgang Koenig Markku Koskenvuo Wolfgang Kratzer Jaana Laitinen Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Ken Sin Lo Stéphane Lobbens Roberto Lorbeer Yingchang Lu François Mach Patrik K E Magnusson Anubha Mahajan Wendy L McArdle Stela McLachlan Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Ramaiah Nagaraja Markus M Nöthen Ilja M Nolte Stefan Pilz Nigel W Rayner Frida Renstrom Rainer Rettig Janina S Ried Stephan Ripke Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher William R Scott Thomas Seufferlein Jianxin Shi Albert Vernon Smith Joanna Smolonska Alice V Stanton Valgerdur Steinthorsdottir Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Jonathan P Tyrer Hae-Won Uh Liesbeth Vandenput Frank C Verhulst Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Helen R Warren Dawn Waterworth Michael N Weedon Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Eoin P Brennan Murim Choi Zari Dastani Alexander W Drong Per Eriksson Anders Franco-Cereceda Jesper R Gådin Ali G Gharavi Michael E Goddard Robert E Handsaker Jinyan Huang Fredrik Karpe Sekar Kathiresan Sarah Keildson Krzysztof Kiryluk Michiaki Kubo Jong-Young Lee Liming Liang Richard P Lifton Baoshan Ma Steven A McCarroll Amy J McKnight Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Yukinori Okada John R B Perry Rajkumar Dorajoo Eva Reinmaa Rany M Salem Niina Sandholm Robert A Scott Lisette Stolk Atsushi Takahashi Toshihiro Tanaka Ferdinand M van 't Hooft Anna A E Vinkhuyzen Harm-Jan Westra Wei Zheng Krina T Zondervan Andrew C Heath Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman John Blangero Pascal Bovet Harry Campbell Mark J Caulfield Giancarlo Cesana Aravinda Chakravarti Daniel I Chasman Peter S Chines Francis S Collins Dana C Crawford L Adrienne Cupples Daniele Cusi John Danesh Ulf de Faire Hester M den Ruijter Anna F Dominiczak Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Stephan B Felix Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Pablo V Gejman Christian Gieger Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman Georg Homuth G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hyppönen Thomas Illig Kevin B Jacobs Marjo-Riitta Jarvelin Karl-Heinz Jöckel Berit Johansen Pekka Jousilahti J Wouter Jukema Antti M Jula Jaakko Kaprio John J P Kastelein Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Paul Knekt Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Frans L Moll Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Pamela A F Madden Gerard Pasterkamp John F Peden Annette Peters Dirkje S Postma Peter P Pramstaller Jackie F Price Lu Qi Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker John D Rioux Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Heribert Schunkert Peter E H Schwarz Peter Sever Alan R Shuldiner Juha Sinisalo Ronald P Stolk Konstantin Strauch Anke Tönjes David-Alexandre Trégouët Angelo Tremblay Elena Tremoli Jarmo Virtamo Marie-Claude Vohl Uwe Völker Gérard Waeber Gonneke Willemsen Jacqueline C Witteman M Carola Zillikens Linda S Adair Philippe Amouyel Folkert W Asselbergs Themistocles L Assimes Murielle Bochud Bernhard O Boehm Eric Boerwinkle Stefan R Bornstein Erwin P Bottinger Claude Bouchard Stéphane Cauchi John C Chambers Stephen J Chanock Richard S Cooper Paul I W de Bakker George Dedoussis Luigi Ferrucci Paul W Franks Philippe Froguel Leif C Groop Christopher A Haiman Anders Hamsten Jennie Hui David J Hunter Kristian Hveem Robert C Kaplan Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Nicholas G Martin Winfried März Mads Melbye Andres Metspalu Susanne Moebus Patricia B Munroe Inger Njølstad Ben A Oostra Colin N A Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Naveed Sattar Eric E Schadt David Schlessinger P Eline Slagboom Harold Snieder Tim D Spector Unnur Thorsteinsdottir Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins David R Weir H-Erich Wichmann James F Wilson Pieter Zanen Ingrid B Borecki Panos Deloukas Caroline S Fox Iris M Heid Jeffrey R O'Connell David P Strachan Kari Stefansson Cornelia M van Duijn Gonçalo R Abecasis Lude Franke Timothy M Frayling Mark I McCarthy Peter M Visscher André Scherag Cristen J Willer Michael Boehnke Karen L Mohlke Cecilia M Lindgren Jacques S Beckmann Inês Barroso Kari E North Erik Ingelsson Joel N Hirschhorn Ruth J F Loos Elizabeth K Speliotes

Nature 2015 Feb;518(7538):197-206

Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382211PMC
February 2015

New genetic loci link adipose and insulin biology to body fat distribution.

Authors:
Dmitry Shungin Thomas W Winkler Damien C Croteau-Chonka Teresa Ferreira Adam E Locke Reedik Mägi Rona J Strawbridge Tune H Pers Krista Fischer Anne E Justice Tsegaselassie Workalemahu Joseph M W Wu Martin L Buchkovich Nancy L Heard-Costa Tamara S Roman Alexander W Drong Ci Song Stefan Gustafsson Felix R Day Tonu Esko Tove Fall Zoltán Kutalik Jian'an Luan Joshua C Randall André Scherag Sailaja Vedantam Andrew R Wood Jin Chen Rudolf Fehrmann Juha Karjalainen Bratati Kahali Ching-Ti Liu Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Georg B Ehret Mary F Feitosa Anuj Goel Anne U Jackson Toby Johnson Marcus E Kleber Kati Kristiansson Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Alena Stančáková Yun Ju Sung Toshiko Tanaka Alexander Teumer Jana V Van Vliet-Ostaptchouk Loïc Yengo Weihua Zhang Eva Albrecht Johan Ärnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Stefan Böhringer Fabrice Bonnet Yvonne Böttcher Marcel Bruinenberg Delia B Carba Ida H Caspersen Robert Clarke E Warwick Daw Joris Deelen Ewa Deelman Graciela Delgado Alex Sf Doney Niina Eklund Michael R Erdos Karol Estrada Elodie Eury Nele Friedrich Melissa E Garcia Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Harald Grallert Tanja B Grammer Jürgen Gräßler Jagvir Grewal Christopher J Groves Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Kauko Heikkilä Karl-Heinz Herzig Quinta Helmer Hans L Hillege Oddgeir Holmen Steven C Hunt Aaron Isaacs Till Ittermann Alan L James Ingegerd Johansson Thorhildur Juliusdottir Ioanna-Panagiota Kalafati Leena Kinnunen Wolfgang Koenig Ishminder K Kooner Wolfgang Kratzer Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon François Mach Patrik Ke Magnusson Anubha Mahajan Wendy L McArdle Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Rebecca Mills Alireza Moayyeri Keri L Monda Simon P Mooijaart Thomas W Mühleisen Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Ramaiah Nagaraja Michael A Nalls Narisu Narisu Nicola Glorioso Ilja M Nolte Matthias Olden Nigel W Rayner Frida Renstrom Janina S Ried Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Bengt Sennblad Thomas Seufferlein Colleen M Sitlani Albert Vernon Smith Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Andreas Tomaschitz Chiara Troffa Floor Va van Oort Niek Verweij Judith M Vonk Lindsay L Waite Roman Wennauer Tom Wilsgaard Mary K Wojczynski Andrew Wong Qunyuan Zhang Jing Hua Zhao Eoin P Brennan Murim Choi Per Eriksson Lasse Folkersen Anders Franco-Cereceda Ali G Gharavi Åsa K Hedman Marie-France Hivert Jinyan Huang Stavroula Kanoni Fredrik Karpe Sarah Keildson Krzysztof Kiryluk Liming Liang Richard P Lifton Baoshan Ma Amy J McKnight Ruth McPherson Andres Metspalu Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Christian Olsson John Rb Perry Eva Reinmaa Rany M Salem Niina Sandholm Eric E Schadt Robert A Scott Lisette Stolk Edgar E Vallejo Harm-Jan Westra Krina T Zondervan Philippe Amouyel Dominique Arveiler Stephan Jl Bakker John Beilby Richard N Bergman John Blangero Morris J Brown Michel Burnier Harry Campbell Aravinda Chakravarti Peter S Chines Simone Claudi-Boehm Francis S Collins Dana C Crawford John Danesh Ulf de Faire Eco Jc de Geus Marcus Dörr Raimund Erbel Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Christian Gieger Vilmundur Gudnason Christopher A Haiman Tamara B Harris Andrew T Hattersley Markku Heliövaara Andrew A Hicks Aroon D Hingorani Wolfgang Hoffmann Albert Hofman Georg Homuth Steve E Humphries Elina Hyppönen Thomas Illig Marjo-Riitta Jarvelin Berit Johansen Pekka Jousilahti Antti M Jula Jaakko Kaprio Frank Kee Sirkka M Keinanen-Kiukaanniemi Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Arthur W Musk Stefan Möhlenkamp Andrew D Morris Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Lyle J Palmer Brenda W Penninx Annette Peters Peter P Pramstaller Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Peter Eh Schwarz Alan R Shuldiner Jan A Staessen Valgerdur Steinthorsdottir Ronald P Stolk Konstantin Strauch Anke Tönjes Angelo Tremblay Elena Tremoli Marie-Claude Vohl Uwe Völker Peter Vollenweider James F Wilson Jacqueline C Witteman Linda S Adair Murielle Bochud Bernhard O Boehm Stefan R Bornstein Claude Bouchard Stéphane Cauchi Mark J Caulfield John C Chambers Daniel I Chasman Richard S Cooper George Dedoussis Luigi Ferrucci Philippe Froguel Hans-Jörgen Grabe Anders Hamsten Jennie Hui Kristian Hveem Karl-Heinz Jöckel Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Winfried März Patricia B Munroe Inger Njølstad Ben A Oostra Colin Na Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Juha Sinisalo P Eline Slagboom Harold Snieder Tim D Spector Kari Stefansson Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Giovanni Veronesi Mark Walker Nicholas J Wareham Hugh Watkins H-Erich Wichmann Goncalo R Abecasis Themistocles L Assimes Sonja I Berndt Michael Boehnke Ingrid B Borecki Panos Deloukas Lude Franke Timothy M Frayling Leif C Groop David J Hunter Robert C Kaplan Jeffrey R O'Connell Lu Qi David Schlessinger David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Cristen J Willer Peter M Visscher Jian Yang Joel N Hirschhorn M Carola Zillikens Mark I McCarthy Elizabeth K Speliotes Kari E North Caroline S Fox Inês Barroso Paul W Franks Erik Ingelsson Iris M Heid Ruth Jf Loos L Adrienne Cupples Andrew P Morris Cecilia M Lindgren Karen L Mohlke

Nature 2015 Feb;518(7538):187-196

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338562PMC
February 2015

Statin-induced insulin resistance through inflammasome activation: sailing between Scylla and Charybdis.

Diabetes 2014 Nov;63(11):3569-71

Department of Medicine, Faculty of Medicine, Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada

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November 2014

Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome.

Rev Endocr Metab Disord 2014 Dec;15(4):299-305

Department of Medicine, Faculty of Medicine and Heart and Lung Institute, Laval University, Québec, QC, Canada,

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December 2014

Defining the role of common variation in the genomic and biological architecture of adult human height.

Authors:
Andrew R Wood Tonu Esko Jian Yang Sailaja Vedantam Tune H Pers Stefan Gustafsson Audrey Y Chu Karol Estrada Jian'an Luan Zoltán Kutalik Najaf Amin Martin L Buchkovich Damien C Croteau-Chonka Felix R Day Yanan Duan Tove Fall Rudolf Fehrmann Teresa Ferreira Anne U Jackson Juha Karjalainen Ken Sin Lo Adam E Locke Reedik Mägi Evelin Mihailov Eleonora Porcu Joshua C Randall André Scherag Anna A E Vinkhuyzen Harm-Jan Westra Thomas W Winkler Tsegaselassie Workalemahu Jing Hua Zhao Devin Absher Eva Albrecht Denise Anderson Jeffrey Baron Marian Beekman Ayse Demirkan Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Ross M Fraser Anuj Goel Jian Gong Anne E Justice Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Julian C Lui Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Michael A Nalls Dale R Nyholt Cameron D Palmer Dorota Pasko Sonali Pechlivanis Inga Prokopenko Janina S Ried Stephan Ripke Dmitry Shungin Alena Stancáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Uzma Afzal Johan Arnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Jennifer L Bolton Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Brendan M Buckley Steven Buyske Ida H Caspersen Peter S Chines Robert Clarke Simone Claudi-Boehm Matthew Cooper E Warwick Daw Pim A De Jong Joris Deelen Graciela Delgado Josh C Denny Rosalie Dhonukshe-Rutten Maria Dimitriou Alex S F Doney Marcus Dörr Niina Eklund Elodie Eury Lasse Folkersen Melissa E Garcia Frank Geller Vilmantas Giedraitis Alan S Go Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Lisette C P G M de Groot Christopher J Groves Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Anke Hannemann Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Gibran Hemani Anjali K Henders Hans L Hillege Mark A Hlatky Wolfgang Hoffmann Per Hoffmann Oddgeir Holmen Jeanine J Houwing-Duistermaat Thomas Illig Aaron Isaacs Alan L James Janina Jeff Berit Johansen Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Juhani Junttila Abel N Kho Leena Kinnunen Norman Klopp Thomas Kocher Wolfgang Kratzer Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon Yingchang Lu Valeriya Lyssenko Patrik K E Magnusson Anubha Mahajan Marc Maillard Wendy L McArdle Colin A McKenzie Stela McLachlan Paul J McLaren Cristina Menni Sigrun Merger Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Narisu Narisu Matthias Nauck Ilja M Nolte Markus M Nöthen Laticia Oozageer Stefan Pilz Nigel W Rayner Frida Renstrom Neil R Robertson Lynda M Rose Ronan Roussel Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher Heribert Schunkert Robert A Scott Joban Sehmi Thomas Seufferlein Jianxin Shi Karri Silventoinen Johannes H Smit Albert Vernon Smith Joanna Smolonska Alice V Stanton Kathleen Stirrups David J Stott Heather M Stringham Johan Sundström Morris A Swertz Ann-Christine Syvänen Bamidele O Tayo Gudmar Thorleifsson Jonathan P Tyrer Suzanne van Dijk Natasja M van Schoor Nathalie van der Velde Diana van Heemst Floor V A van Oort Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Melanie Waldenberger Roman Wennauer Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman Sven Bergmann Reiner Biffar John Blangero Dorret I Boomsma Stefan R Bornstein Pascal Bovet Paolo Brambilla Morris J Brown Harry Campbell Mark J Caulfield Aravinda Chakravarti Rory Collins Francis S Collins Dana C Crawford L Adrienne Cupples John Danesh Ulf de Faire Hester M den Ruijter Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Ron T Gansevoort Pablo V Gejman Christian Gieger Alain Golay Omri Gottesman Vilmundur Gudnason Ulf Gyllensten David W Haas Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew C Heath Christian Hengstenberg Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hypponen Kevin B Jacobs Marjo-Riitta Jarvelin Pekka Jousilahti Antti M Jula Jaakko Kaprio John J P Kastelein Manfred Kayser Frank Kee Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Jaspal S Kooner Charles Kooperberg Seppo Koskinen Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Sara Lupoli Pamela A F Madden Satu Männistö Paolo Manunta André Marette Tara C Matise Barbara McKnight Thomas Meitinger Frans L Moll Grant W Montgomery Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Willem H 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Michael E Goddard Peter M Visscher Joel N Hirschhorn Timothy M Frayling

Nat Genet 2014 Nov 5;46(11):1173-86. Epub 2014 Oct 5.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250049PMC
November 2014

Early development of calcific aortic valve disease and left ventricular hypertrophy in a mouse model of combined dyslipidemia and type 2 diabetes mellitus.

Arterioscler Thromb Vasc Biol 2014 Oct 14;34(10):2283-91. Epub 2014 Aug 14.

From the Heart and Lung Institute, Laval University, Sainte-Foy, Québec, Canada (K.L.Q., R.B., D.L., M.-A.L., D.E.H., M.-C.B., D.F., X.P.F., R.K.A., P.P., Y.D., P.M., A.M.); and Department of Biology, York University, Toronto, Ontario, Canada (X.P.F., G.S.).

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October 2014

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.

Gut 2015 Jun 30;64(6):872-83. Epub 2014 Jul 30.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Quebec Heart and Lung Institute, Quebec, Quebec, Canada Institute of Nutrition and Functional Foods, Laval University, Quebec, Quebec, Canada.

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June 2015

Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease.

Diabetes 2014 Dec 9;63(12):4291-301. Epub 2014 Jul 9.

Faculté de Pharmacie, Université Laval, Québec, Canada Axe Neurosciences, Centre de Recherche du Centre Hospitalier de l'Université Laval, Québec, Canada Institut des Nutraceutiques et des Aliments Fonctionnels, Université Laval, Québec, Canada

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December 2014

Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis.

Nat Med 2014 Jun 11;20(6):664-9. Epub 2014 May 11.

1] Department of Medicine, Québec Heart and Lung Institute, Laval University, Québec, Québec, Canada. [2] Institute of Nutrition and Functional Foods, Laval University, Québec, Québec, Canada.

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June 2014

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.

FASEB J 2014 Jul 20;28(7):3211-24. Epub 2014 Mar 20.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unité (U)1016, Institut Cochin, Paris, France; Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France;

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July 2014

Yogurt consumption and impact on health: focus on children and cardiometabolic risk.

Am J Clin Nutr 2014 May 19;99(5 Suppl):1243S-7S. Epub 2014 Mar 19.

Department of Medicine, Faculty of Medicine, Cardiology Axis of the Institut Universitaire de Cardiologie et de Pneumologie de Québec (Hôpital Laval), Quebec City, Canada, and The Institute of Nutrition and Functional Foods, Laval University, Quebec City, Canada (AM and EP-D).

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May 2014

Modulation of Strawberry/Cranberry Phenolic Compounds Glucuronidation by Co-Supplementation with Onion: Characterization of Phenolic Metabolites in Rat Plasma Using an Optimized μSPE-UHPLC-MS/MS Method.

J Agric Food Chem 2014 Apr 26;62(14):3244-3256. Epub 2014 Mar 26.

Institute of Nutrition and Functional Foods (INAF), Laval University , 2440 Boulevard Hochelaga, Québec (QC) G1V 0A6, Canada.

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April 2014