Andre Luis Santos

Andre Luis Souza Dos Santos

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Andre Luis Santos

Andre Luis Souza Dos Santos

Publications by authors named "Andre Luis Souza Dos Santos"

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1PubMed Central Citations

Current Challenges and Updates on the Therapy of Fungal Infections.

Curr Top Med Chem 2019 ;19(7):495-499

Laboratorio de Estudos Avancados de Microrganismos Emergentes e Resistentes, Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.2174/156802661907190531093808DOI Listing
July 2019

Repositioning of HIV Aspartyl Peptidase Inhibitors for Combating the Neglected Human Pathogen Trypanosoma cruzi.

Curr Med Chem 2019 Jun 10. Epub 2019 Jun 10.

Laboratório de Estudos Integrados em Bioquímica Microbiana Departamento de Microbiologia Geral Instituto de Microbiologia Paulo de Góes Universidade Federal do Rio de Janeiro - UFRJ Rio de Janeiro, Brazil RIO DE JANEIRO, Rio de Janeiro. Brazil.

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http://dx.doi.org/10.2174/0929867326666190610152934DOI Listing
June 2019

Leishmaniasis and Chagas Disease - Neglected Tropical Diseases: Treatment Updates.

Curr Top Med Chem 2019 ;19(3):174-177

Laboratorio de Estudos Avancados de Microrganismos Emergentes e Resistentes, Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.2174/156802661903190328155136DOI Listing
April 2019

Anti-Trichomonas vaginalis activity of 1,10-phenanthroline-5,6-dione-based metallodrugs and synergistic effect with metronidazole.

Parasitology 2018 Sep 12:1-5. Epub 2018 Sep 12.

Laboratório de Pesquisa em Parasitologia, Faculdade de Farmácia,Universidade Federal do Rio Grande do Sul,Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS,Brazil.

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http://dx.doi.org/10.1017/S003118201800152XDOI Listing
September 2018

Susceptibility of promastigotes and intracellular amastigotes from distinct Leishmania species to the calpain inhibitor MDL28170.

Parasitol Res 2018 Jul 4;117(7):2085-2094. Epub 2018 May 4.

Laboratório de Investigação de Peptidases, Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1007/s00436-018-5894-7DOI Listing
July 2018

What are the advantages of living in a community? A microbial biofilm perspective!

Mem Inst Oswaldo Cruz 2018 Jul 26;113(9):e180212. Epub 2018 Jul 26.

Iran University of Medical Sciences, School of Medicine, Department of Medical Mycology and Parasitology, Tehran, Iran.

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http://dx.doi.org/10.1590/0074-02760180212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057313PMC
July 2018

EDITORIAL: Old Drugs × New Perspectives/New Compounds × Old Necessities: Focusing on Combating Microbial Resistance - Part II.

Curr Top Med Chem 2017 ;17(11):1235-1236

Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.2174/156802661711170223221749DOI Listing
April 2018

Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis?

Parasitology 2017 02 21;144(2):117-123. Epub 2016 Nov 21.

Laboratório de Estudos Integrados em Protozoologia,Instituto Oswaldo Cruz/FIOCRUZ,Rio de Janeiro,Brazil.

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http://dx.doi.org/10.1017/S003118201600189XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300003PMC
February 2017

Fungal Biofilm - A Real Obstacle against an Efficient Therapy: Lessons from Candida.

Curr Top Med Chem 2017 Jan 5. Epub 2017 Jan 5.

Laboratório de Investigação de Peptidases (LIP), Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes (IMPG), Bloco E - subsolo, sala 05, Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-902, Brazil.

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January 2017

1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective in Disturbing Crucial Physiological Events of .

Front Microbiol 2017 30;8:76. Epub 2017 Jan 30.

Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz Rio de Janeiro, Brazil.

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http://dx.doi.org/10.3389/fmicb.2017.00076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276843PMC
January 2017

Conidial germination in Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lomentospora prolificans: influence of growth conditions and antifungal susceptibility profiles.

Mem Inst Oswaldo Cruz 2016 Jun;0

Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Departamento de Microbiologia Geral, Laboratório de Investigação de Peptidases, Rio de Janeiro, RJ, Brasil.

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http://dx.doi.org/10.1590/0074-02760160200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957502PMC
June 2016

Editorial: New Antimicrobial Therapeutics.

Curr Med Chem 2015 ;22(18):2112-5

Laboratorio de Investigacao de Peptidases (LIP) Departamento de Microbiologia Geral Instituto de Microbiologia Paulo de Goes (IMPG) Universidade Federal do Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho 373, Rio de Janeiro, 21941-902 Brazil.

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April 2016

Protease and phospholipase activities of Candida spp. isolated from cutaneous candidiasis.

Rev Iberoam Micol 2015 Apr-Jun;32(2):122-5. Epub 2014 May 20.

Instituto Biomédico, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S11301406140004
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http://dx.doi.org/10.1016/j.riam.2014.01.003DOI Listing
February 2016

Expression of calpain-like proteins and effects of calpain inhibitors on the growth rate of Angomonas deanei wild type and aposymbiotic strains.

BMC Microbiol 2015 Sep 29;15:188. Epub 2015 Sep 29.

Laboratório de Investigação de Peptidases, Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1186/s12866-015-0519-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587752PMC
September 2015

1,10-phenanthroline inhibits the metallopeptidase secreted by Phialophora verrucosa and modulates its growth, morphology and differentiation.

Mycopathologia 2015 Apr 12;179(3-4):231-42. Epub 2014 Dec 12.

Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1007/s11046-014-9832-7DOI Listing
April 2015

Cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgut.

PLoS Negl Trop Dis 2012 13;6(12):e1958. Epub 2012 Dec 13.

Laboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1371/journal.pntd.0001958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521651PMC
May 2013

Effect of chelating agents on the growth, surface polypeptide synthesis and interaction of Streptococcus agalactiae with human epithelial cells.

Mol Med Rep 2009 Jan-Feb;2(1):81-4

Departamento de Biologia Celular, Instituto Biologia Roberto Alcântara Gomes (IBRAG), Universidade do Estado do Rio de Janeiro (UERJ), 20550-013 Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.3892/mmr_00000065DOI Listing
October 2012

Effects of direct electric current on Herpetomonas samuelpessoai: An ultrastructural study.

Bioelectromagnetics 2012 May 19;33(4):334-45. Epub 2011 Oct 19.

Laboratory of Multidisciplinary Pharmaceutical Sciences, Department of Drugs, Faculty of Pharmacy, Centre of Health Sciences (CCS), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1002/bem.20712DOI Listing
May 2012

Proteomic analysis of the secretions of Pseudallescheria boydii, a human fungal pathogen with unknown genome.

J Proteome Res 2012 Jan 5;11(1):172-88. Epub 2011 Dec 5.

Laboratório de Estudos Integrados em Bioquímica Microbiana, Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes (IMPPG), Universidade Federal do Rio de Janeiro , Rio de Janeiro, Brazil.

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http://pubs.acs.org/doi/10.1021/pr200875x
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http://dx.doi.org/10.1021/pr200875xDOI Listing
January 2012

Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes.

Mem Inst Oswaldo Cruz 2011 Jun;106(4):507-9

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

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http://www.scielo.br/pdf/mioc/v106n4/21.pdf
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http://dx.doi.org/10.1590/s0074-02762011000400021DOI Listing
June 2011

Protease expression by microorganisms and its relevance to crucial physiological/pathological events.

World J Biol Chem 2011 Mar;2(3):48-58

André Luis Souza dos Santos, Laboratory of Multidisciplinary Studies on Microbial Biochemistry, Department of General Microbiology, Institute of Microbiology Prof. Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, RJ 21941-902, Brazil.

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http://dx.doi.org/10.4331/wjbc.v2.i3.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083995PMC
March 2011

Detection of matrix metallopeptidase-9-like proteins in Trypanosoma cruzi.

Exp Parasitol 2010 Jul 6;125(3):256-63. Epub 2010 Feb 6.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade Federal do Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1016/j.exppara.2010.01.023DOI Listing
July 2010

Phospholipase and esterase production by clinical strains of Fonsecaea pedrosoi and their interactions with epithelial cells.

Mycopathologia 2010 Jul 1;170(1):31-7. Epub 2010 Mar 1.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1007/s11046-010-9293-6DOI Listing
July 2010

A new experimental culture medium for cultivation of Leishmania amazonensis: its efficacy for the continuous in vitro growth and differentiation of infective promastigote forms.

Parasitol Res 2010 Apr 23;106(5):1249-52. Epub 2010 Feb 23.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Bloco I, Ilha do Fundão, Rio de Janeiro, RJ, 21941-902, Brazil.

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http://dx.doi.org/10.1007/s00436-010-1775-4DOI Listing
April 2010

HIV aspartyl protease inhibitors as promising compounds against Candida albicans André Luis Souza dos Santos.

World J Biol Chem 2010 Feb;1(2):21-30

André Luis Souza dos Santos, Laboratory of Multidisciplinary Studies on Microbial Biochemistry, Department of General Microbiology, Institute of Microbiology Prof. Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, RJ 21941-902, Brazil.

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http://dx.doi.org/10.4331/wjbc.v1.i2.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083943PMC
February 2010

Proteins and peptidases from conidia and mycelia of Scedosporium apiospermum strain HLPB.

Mycopathologia 2009 Jan 23;167(1):25-30. Epub 2008 Aug 23.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade Federal do Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1007/s11046-008-9147-7DOI Listing
January 2009

A 25-kDa serine peptidase with keratinolytic activity secreted by Coccidioides immitis.

Mycopathologia 2008 Jul 2;166(1):35-40. Epub 2008 Apr 2.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro 21941-902, RJ, Brazil.

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http://search.proquest.com/openview/20774969c4e45962e003e780
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http://link.springer.com/10.1007/s11046-008-9116-1
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http://dx.doi.org/10.1007/s11046-008-9116-1DOI Listing
July 2008

Metallopeptidases produced by group B Streptococcus: influence of proteolytic inhibitors on growth and on interaction with human cell lineages.

Int J Mol Med 2008 Jul;22(1):119-25

Departamento de Biologia Celular e Genética, Instituto Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

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July 2008

Analysis of Peptidases in Non-Infected and Trypanosoma cruzi-Infected Mouse Embryo Hepatocyte Cells.

Int J Biomed Sci 2008 Jun;4(2):97-102

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade Federal do Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro, RJ, Brazil;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614691PMC
June 2008

Heterogeneous production of metallo-type peptidases in parasites belonging to the family Trypanosomatidae.

Eur J Protistol 2008 May 17;44(2):103-13. Epub 2007 Oct 17.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal do Rio de Janeiro, Cidade Universitária, Ilha do Fundao, 21941-902 Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1016/j.ejop.2007.08.006DOI Listing
May 2008

Effect of suramin on the human pathogen Candida albicans: implications on the fungal development and virulence.

FEMS Immunol Med Microbiol 2007 Nov 29;51(2):399-406. Epub 2007 Aug 29.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1111/j.1574-695X.2007.00321.xDOI Listing
November 2007

Effect of sphingosine and phorbol-12-myristate-13-acetate on the growth and dimethylsulfoxide-induced differentiation in the insect trypanosomatid Herpetomonas samuelpessoai.

Mem Inst Oswaldo Cruz 2007 Aug;102(5):601-4

Laboratório de Estudos Integrados em Bioquímica Microbiana, Universidade Federal do Rio de Janeiro, RJ, Fiocruz, Rio de Janeiro, RJ, Brasil.

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http://dx.doi.org/10.1590/s0074-02762007005000059DOI Listing
August 2007

Secretory aspartyl peptidase activity from mycelia of the human fungal pathogen Fonsecaea pedrosoi: effect of HIV aspartyl proteolytic inhibitors.

Res Microbiol 2006 Nov 17;157(9):819-26. Epub 2006 Aug 17.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1016/j.resmic.2006.07.003DOI Listing
November 2006

Extracellular peptidase in the fungal pathogen Pseudallescheria boydii.

Curr Microbiol 2006 Jul 9;53(1):18-22. Epub 2006 Jun 9.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade Federal do Rio de Janeiro (UFRJ), Ilha do Fundão, Brazil.

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http://dx.doi.org/10.1007/s00284-005-0156-1DOI Listing
July 2006

Secretion of serine peptidase by a clinical strain of Candida albicans: influence of growth conditions and cleavage of human serum proteins and extracellular matrix components.

FEMS Immunol Med Microbiol 2006 Mar;46(2):209-20

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1111/j.1574-695X.2005.00023.xDOI Listing
March 2006

The major chromoblastomycosis fungal pathogen, Fonsecaea pedrosoi, extracellularly releases proteolytic enzymes whose expression is modulated by culture medium composition: implications on the fungal development and cleavage of key's host structures.

FEMS Immunol Med Microbiol 2006 Feb;46(1):21-9

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1111/j.1574-695X.2005.00003.xDOI Listing
February 2006

Insights into the role of gp63-like proteins in lower trypanosomatids.

FEMS Microbiol Lett 2006 Jan;254(1):149-56

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1111/j.1574-6968.2005.00022.xDOI Listing
January 2006

Candida guilliermondii isolated from HIV-infected human secretes a 50 kDa serine proteinase that cleaves a broad spectrum of proteinaceous substrates.

FEMS Immunol Med Microbiol 2005 Jan;43(1):13-20

Departamento de Microbiologia Geral, Laboratório de Biologia de Protistas, Instituto de Microbiologia Professor Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, 21941-590 Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1016/j.femsim.2004.06.022DOI Listing
January 2005

Differential lectin recognition of glycoproteins in choanomastigote-shaped trypanosomatids: taxonomic implications.

FEMS Microbiol Lett 2004 Feb;231(2):171-6

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Bloco I, Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ 21941-590, Brazil.

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http://dx.doi.org/10.1016/S0378-1097(03)00915-7DOI Listing
February 2004

Leishmania (Leishmania) amazonensis: differential expression of proteinases and cell-surface polypeptides in avirulent and virulent promastigotes.

Exp Parasitol 2003 Jul-Aug;104(3-4):104-12

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Bloco I, Universidade do Brasil (UFRJ), Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.

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November 2003

Herpetomonas samuelpessoai: dimethylsulfoxide-induced differentiation is influenced by proteinase expression.

Curr Microbiol 2003 Jan;46(1):11-7

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade do Brasil (UFRJ), Ilha do Fundão, 21941-590, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1007/s00284-002-3795-5DOI Listing
January 2003

Changes of sialomolecules during the dimethylsulfoxide-induced differentiation of Herpetomonas samuelpessoai.

Parasitol Res 2002 Nov 4;88(11):951-5. Epub 2002 Jul 4.

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof Paulo de Góes, Centro de Ciências da Saúde, Bloco I, Universidade do Brasil (UFRJ), Ilha do Fundão, 21941-590, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1007/s00436-002-0685-5DOI Listing
November 2002

Activation of the glycosylphosphatidylinositol-anchored membrane proteinase upon release from Herpetomonas samuelpessoai by phospholipase C.

Curr Microbiol 2002 Oct;45(4):293-8

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Bloco I, Universidade do Brasil (UFRJ), Ilha do Fundão, 21941-590, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1007/s00284-002-3752-3DOI Listing
October 2002

Detection of sialoglycomolecules in five plant trypanosomatids and in an insect phytophagous isolate.

FEMS Microbiol Lett 2002 Aug;214(1):19-23

Departamento de Microbiologia Geral, Instituto de Microbiologia Prof. Paulo de Góes (IMPPG), Centro de Ciências da Saúde (CCS), Bloco I, Universidade do Brasil (UFRJ), Ilha do Fundão, 21941-590 Rio de Janeiro, Brazil.

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http://femsle.oxfordjournals.org/content/femsle/214/1/19.ful
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http://dx.doi.org/10.1111/j.1574-6968.2002.tb11319.xDOI Listing
August 2002