Andre Lechel

Andre Lechel

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Andre Lechel

Andre Lechel

Publications by authors named "Andre Lechel"

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Remodelling and Improvements in Organoid Technology to Study Liver Carcinogenesis in a Dish.

Stem Cells Int 2019 19;2019:3831213. Epub 2019 Feb 19.

Department of Internal Medicine I, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1155/2019/3831213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399527PMC
February 2019

Targeting the correct target in HCC.

Gut 2017 08 18;66(8):1352-1354. Epub 2017 Jan 18.

Department of Internal Medicine I, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1136/gutjnl-2016-313462DOI Listing
August 2017

Early HCC treatment: a future strategy against interferon/miR-484 axis to revert precancerous lesions?

Gut 2016 07 4;65(7):1073-4. Epub 2016 Mar 4.

Inserm, U1016, Institut Cochin, Paris, France Cnrs, UMR8104, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France Equipe labellisée LNCC, Paris, France.

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http://dx.doi.org/10.1136/gutjnl-2016-311446DOI Listing
July 2016

Telomerase: The Devil Inside.

Genes (Basel) 2016 Jul 29;7(8). Epub 2016 Jul 29.

Department of Urology, Ulm University, 89081 Ulm, Germany.

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http://dx.doi.org/10.3390/genes7080043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999831PMC
July 2016

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

EMBO J 2015 Mar 21;34(5):624-40. Epub 2015 Jan 21.

Leibniz Institute for Age Research - Fritz Lipmann Institute e.V. (FLI), Jena, Germany Research Group on Stem Cell Aging, Jena University Hospital (UKJ), Jena, Germany

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http://dx.doi.org/10.15252/embj.201490700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365032PMC
March 2015

Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions.

Nat Commun 2014 Aug 13;5:4599. Epub 2014 Aug 13.

Clinic of Dermatology and Allergic Diseases, University Medical Center, Albert-Einstein-Allee 23, 89081 Ulm, Germany.

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http://www.nature.com/articles/ncomms5599
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http://dx.doi.org/10.1038/ncomms5599DOI Listing
August 2014

p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.

Cell 2014 Jul;158(3):579-92

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA; Howard Hughes Medical Institute, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221237PMC
July 2014

Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.

Neuroreport 2014 Mar;25(5):335-9

aCNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss bInstitute of Molecular Medicine and Max-Planck-Research-Group on Stem Cell Ageing, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1097/WNR.0000000000000099DOI Listing
March 2014

Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.

J Proteomics 2013 Oct 19;91:515-35. Epub 2013 Aug 19.

Institute of Molecular Medicine Cell Research, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.jprot.2013.08.007DOI Listing
October 2013

Telomere length in mantle cell lymphoma.

Blood 2013 Feb 14;121(7):1184-7. Epub 2012 Dec 14.

Department of Internal Medicine III, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1182/blood-2012-08-452649DOI Listing
February 2013

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

Gastroenterology 2012 May 15;142(5):1229-1239.e3. Epub 2012 Feb 15.

Institute of Molecular Medicine and Max Planck Research Group on Stem Cell Aging, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1053/j.gastro.2012.02.009DOI Listing
May 2012

CHK2-independent induction of telomere dysfunction checkpoints in stem and progenitor cells.

EMBO Rep 2010 Aug 25;11(8):619-25. Epub 2010 Jun 25.

Department of Molecular Medicine, and Max Planck Research Group on Stem Cell Aging, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/embor.2010.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920444PMC
August 2010

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

Nat Genet 2009 Oct 30;41(10):1138-43. Epub 2009 Aug 30.

Institute of Molecular Medicine and Max-Planck-Research Department on Stem Cell Aging, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/ng.426DOI Listing
October 2009

Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri.

Mech Ageing Dev 2009 May 22;130(5):290-6. Epub 2009 Jan 22.

Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany.

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http://dx.doi.org/10.1016/j.mad.2009.01.003DOI Listing
May 2009

Telomeres and telomerase: new targets for the treatment of liver cirrhosis and hepatocellular carcinoma.

J Hepatol 2004 Sep;41(3):491-7

Department of Gastroenterology, Hepatology, and Endocrinology, Medical School Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.jhep.2004.06.010DOI Listing
September 2004