Andre G Tempone

Andre G Tempone

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Andre G Tempone

Publications by authors named "Andre G Tempone"

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Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi.

Eur J Med Chem 2019 Aug 2;176:162-174. Epub 2019 May 2.

Centre for Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, 01246-000, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.05.001DOI Listing
August 2019

Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential.

Fitoterapia 2019 Jul 2;137:104251. Epub 2019 Jul 2.

Center of Natural Sciences and Humanities, Federal University of ABC, Santo Andre, SP 09210-180, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104251DOI Listing
July 2019

Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis.

Bioorg Med Chem Lett 2019 Jun 12;29(12):1459-1462. Epub 2019 Apr 12.

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP 09210-580, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X193024
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http://dx.doi.org/10.1016/j.bmcl.2019.04.020DOI Listing
June 2019

Antitrypanosomal activity and effect in plasma membrane permeability of (-)-bornyl p-coumarate isolated from Piper cernuum (Piperaceae).

Bioorg Chem 2019 May 20;89:103001. Epub 2019 May 20.

Center of Natural Sciences and Humanities, Universidade Federal do ABC, 09210-580 Santo Andre, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103001DOI Listing
May 2019

Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives.

Bioorg Chem 2019 May 18;89:102996. Epub 2019 May 18.

Departamento de Ciências Farmacêuticas, Universidade Federal de São Paulo, Rua São Nicolau 210, 09913-030 Diadema, SP, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00452068183138
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http://dx.doi.org/10.1016/j.bioorg.2019.102996DOI Listing
May 2019

Antitrypanosomal activity of isololiolide isolated from the marine hydroid Macrorhynchia philippina (Cnidaria, Hydrozoa).

Bioorg Chem 2019 May 20;89:103002. Epub 2019 May 20.

Centre for Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo 01246-000, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103002DOI Listing
May 2019

Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria.

Phytomedicine 2019 Feb 9;54:302-307. Epub 2018 Oct 9.

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-180, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.09.236DOI Listing
February 2019

Activity of the antiarrhythmic drug amiodarone against () : an in vitro and in vivo approach.

J Venom Anim Toxins Incl Trop Dis 2018 25;24:29. Epub 2018 Oct 25.

2Centre for Parasitology and Mycology, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, 8°, Andar. Cerqueira César, São Paulo, SP CEP 01246-902 Brazil.

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http://dx.doi.org/10.1186/s40409-018-0166-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203271PMC
October 2018

Antiparasitic activity of new gibbilimbol analogues and SAR analysis through efficiency and statistical methods.

Eur J Pharm Sci 2018 Sep 21;122:31-41. Epub 2018 Jun 21.

Departamento de Ciências Farmacêuticas, Universidade Federal de São Paulo, Rua São Nicolau 210, 09913-030 Diadema, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2018.06.023DOI Listing
September 2018

Neolignans isolated from twigs of Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity.

J Venom Anim Toxins Incl Trop Dis 2018 27;24:27. Epub 2018 Sep 27.

1Center of Natural Sciences and Humanities, Federal University of ABC (UFBC), Avenida dos Estados 5001, Santo Andre, SP 09210-580 Brazil.

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https://jvat.biomedcentral.com/articles/10.1186/s40409-018-0
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http://dx.doi.org/10.1186/s40409-018-0164-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161432PMC
September 2018

Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae).

Fitoterapia 2018 Mar 18;125:55-58. Epub 2017 Dec 18.

Center of Natural Sciences and Humanities, Federal University of ABC, São Paulo 09210-580, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.12.016DOI Listing
March 2018

New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum.

Chem Biol Drug Des 2017 Nov 3;90(5):1007-1011. Epub 2017 May 3.

Departamento de Ciências Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.

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http://dx.doi.org/10.1111/cbdd.12986DOI Listing
November 2017

Membrane targeting peptides toward antileishmanial activity: Design, structural determination and mechanism of interaction.

Biochim Biophys Acta Gen Subj 2017 Nov 2;1861(11 Pt A):2861-2871. Epub 2017 Aug 2.

Departamento de Física, Universidade Estadual Paulista, São José do Rio Preto, SP, Brazil; Departamento de Química e Ciências Ambientais, Universidade Estadual Paulista, São José do Rio Preto, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.08.003DOI Listing
November 2017

Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages.

Chem Biol Interact 2017 Nov 31;277:55-61. Epub 2017 Aug 31.

Center of Natural Sciences and Humanities, Federal University of ABC, Santo Andre, SP, 09210-180, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2017.08.017DOI Listing
November 2017

Antileishmanial Activity and Immunomodulatory Effects of Tricin Isolated from Leaves of Casearia arborea (Salicaceae).

Chem Biodivers 2017 May;14(5)

Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, Rua Prof. Artur Riedel, n° 275 - Jd. Eldorado, CEP 09972-270, Diadema, São Paulo, Brazil.

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http://dx.doi.org/10.1002/cbdv.201600458DOI Listing
May 2017

Bioactivity-guided isolation of laevicarpin, an antitrypanosomal and anticryptococcal lactam from Piper laevicarpu (Piperaceae).

Fitoterapia 2016 Jun 12;111:24-8. Epub 2016 Apr 12.

Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, 09972-270, São Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2016.04.005DOI Listing
June 2016

Gibbilimbol analogues as antiparasitic agents--Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum.

Bioorg Med Chem Lett 2016 Feb 16;26(4):1180-3. Epub 2016 Jan 16.

Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema, SP 09913-030, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.01.040DOI Listing
February 2016

Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum.

Parasitol Res 2015 Dec 7;114(12):4625-35. Epub 2015 Sep 7.

Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, 30130-100, Minas Gerais, Brazil.

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http://dx.doi.org/10.1007/s00436-015-4708-4DOI Listing
December 2015

Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula.

J Nat Prod 2015 May 29;78(5):1101-12. Epub 2015 Apr 29.

†Instituto de Química de São Carlos, Universidade de São Paulo, CP 780, CEP 13560-970 São Carlos, SP, Brazil.

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http://dx.doi.org/10.1021/acs.jnatprod.5b00070DOI Listing
May 2015

Alchornedine, a new anti-trypanosomal guanidine alkaloid from Alchornea glandulosa.

Planta Med 2014 Oct 1;80(15):1310-4. Epub 2014 Sep 1.

Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1055/s-0034-1382994DOI Listing
October 2014

Antiparasitic activity and effect of casearins isolated from Casearia sylvestris on Leishmania and Trypanosoma cruzi plasma membrane.

Phytomedicine 2014 Apr 18;21(5):676-81. Epub 2014 Feb 18.

Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, 09972-270 Diadema, SP, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09447113140002
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http://dx.doi.org/10.1016/j.phymed.2014.01.004DOI Listing
April 2014

Combination therapy with nitazoxanide and amphotericin B, Glucantime®, miltefosine and sitamaquine against Leishmania (Leishmania) infantum intracellular amastigotes.

Acta Trop 2014 Feb 13;130:112-6. Epub 2013 Nov 13.

Departamento de Parasitologia, Instituto Adolfo Lutz, Av. Dr. Arnaldo 351, 8° andar, CEP 01246-000 São Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.actatropica.2013.11.003DOI Listing
February 2014

Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators.

Bioorg Med Chem 2013 Feb 27;21(3):805-13. Epub 2012 Nov 27.

Institute of Pharmaceutical Science, School of Biomedical Sciences, King's College London, SE19NH, UK.

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http://dx.doi.org/10.1016/j.bmc.2012.11.009DOI Listing
February 2013

Leishmanicidal activity of an alkenylphenol from Piper malacophyllum is related to plasma membrane disruption.

Exp Parasitol 2012 Nov 5;132(3):383-7. Epub 2012 Sep 5.

Instituto de Química, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.

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http://dx.doi.org/10.1016/j.exppara.2012.08.019DOI Listing
November 2012

Effectiveness of liposomal buparvaquone in an experimental hamster model of Leishmania (L.) infantum chagasi.

Exp Parasitol 2012 Mar 20;130(3):195-9. Epub 2012 Jan 20.

Department of Parasitology, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, 8° Andar. Cerqueira César, CEP 01246-902 São Paulo, SP, Brazil.

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https://linkinghub.elsevier.com/retrieve/pii/S00144894120002
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http://dx.doi.org/10.1016/j.exppara.2012.01.010DOI Listing
March 2012

In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae).

Exp Parasitol 2012 Feb 28;130(2):141-5. Epub 2011 Nov 28.

Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.

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http://dx.doi.org/10.1016/j.exppara.2011.11.002DOI Listing
February 2012

Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae).

Parasitol Res 2012 Jan 26;110(1):95-101. Epub 2011 May 26.

Centro de Ciências e Humanidades e Centro de Ciências Biológias e da Saúde, Universidade Presbiteriana Mackenzie, 01302-907, São Paulo, SP, Brazil.

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http://dx.doi.org/10.1007/s00436-011-2454-9DOI Listing
January 2012

Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae).

Parasitol Res 2011 Jul 18;109(1):231-6. Epub 2011 Jan 18.

Laboratorio de Toxinologia Aplicada, Departamento de Parasitologia, Instituto Adolfo Lutz, Av. Dr. Arnaldo, 355, 8o andar, 01246-000 São Paulo, SP, Brazil.

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http://dx.doi.org/10.1007/s00436-010-2229-8DOI Listing
July 2011

In vitro and experimental therapeutic studies of the calcium channel blocker bepridil: detection of viable Leishmania (L.) chagasi by real-time PCR.

Exp Parasitol 2011 Jun 24;128(2):111-5. Epub 2011 Feb 24.

Laboratory of Applied Toxinology on Anti-Parasitic Drugs, Department of Parasitology, Instituto Adolfo Lutz Avenida Dr. Arnaldo, 351, 8 andar. Cerqueira César, CEP 01246-902 São Paulo, SP, Brazil.

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http://dx.doi.org/10.1016/j.exppara.2011.02.021DOI Listing
June 2011

Current approaches to discover marine antileishmanial natural products.

Planta Med 2011 Apr 17;77(6):572-85. Epub 2011 Jan 17.

Department of Parasitology, Laboratory of Applied Toxinology on Anti-parasitic Drugs, Instituto Adolfo Lutz, São Paulo, SP, Brazil.

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http://dx.doi.org/10.1055/s-0030-1250663DOI Listing
April 2011

Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.

Bioorg Med Chem 2010 Nov 15;18(22):8044-53. Epub 2010 Sep 15.

Laboratory of Applied Toxinology on Antiparasitic Drugs, Department of Parasitology, Instituto Adolfo Lutz. Avenida Dr. Arnaldo, 351, 8° andar. Cerqueira Cesar, CEP 01246-902 São Paulo, SP, Brazil.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896100083
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http://dx.doi.org/10.1016/j.bmc.2010.09.015DOI Listing
November 2010

Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae).

Parasitol Res 2010 Apr 18;106(5):1245-8. Epub 2010 Feb 18.

Departamento de Ciências Exatas e da Terra, Universidade Federal de São Paulo-Campus Diadema, 09972-270, Diadema, São Paulo, Brazil.

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http://dx.doi.org/10.1007/s00436-010-1771-8DOI Listing
April 2010

Isolation of antileishmanial sterol from the fruits of Cassia fistula using bioguided fractionation.

Phytother Res 2007 Jul;21(7):644-7

Centro de Estudos Químicos, UNIFIEO, Centro Universitário FIEO, Av. Franz Voegeli, 300 Bloco Branco, 4 andar. CEP, Osasco, SP, Brasil.

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http://dx.doi.org/10.1002/ptr.2131DOI Listing
July 2007