Andre Franke

Andre Franke

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Andre Franke

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A disease-specific decline of the relative abundance of Bifidobacterium in patients with autoimmune hepatitis.

Aliment Pharmacol Ther 2020 Jun 7;51(12):1417-1428. Epub 2020 May 7.

1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/apt.15754DOI Listing
June 2020

RE: Oral leukoplakia and risk of progression to oral cancer: A population-based cohort study.

J Natl Cancer Inst 2020 Jun 1. Epub 2020 Jun 1.

Klinik für Mund-, Kiefer- und Gesichtschirurgie, Marienhospital Stuttgart, Stuttgart, Germany.

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http://dx.doi.org/10.1093/jnci/djaa074DOI Listing
June 2020

Amino acid encoding for deep learning applications.

BMC Bioinformatics 2020 Jun 9;21(1):235. Epub 2020 Jun 9.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1186/s12859-020-03546-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285590PMC
June 2020

Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

Authors:
David Ellinghaus Frauke Degenhardt Luis Bujanda Maria Buti Agustín Albillos Pietro Invernizzi Javier Fernández Daniele Prati Guido Baselli Rosanna Asselta Marit M Grimsrud Chiara Milani Fátima Aziz Jan Kässens Sandra May Mareike Wendorff Lars Wienbrandt Florian Uellendahl-Werth Tenghao Zheng Xiaoli Yi Raúl de Pablo Adolfo G Chercoles Adriana Palom Alba-Estela Garcia-Fernandez Francisco Rodriguez-Frias Alberto Zanella Alessandra Bandera Alessandro Protti Alessio Aghemo Ana Lleo Andrea Biondi Andrea Caballero-Garralda Andrea Gori Anja Tanck Anna Carreras Nolla Anna Latiano Anna Ludovica Fracanzani Anna Peschuck Antonio Julià Antonio Pesenti Antonio Voza David Jiménez Beatriz Mateos Beatriz Nafria Jimenez Carmen Quereda Cinzia Paccapelo Christoph Gassner Claudio Angelini Cristina Cea Aurora Solier David Pestaña Eduardo Muñiz-Diaz Elena Sandoval Elvezia M Paraboschi Enrique Navas Félix García Sánchez Ferruccio Ceriotti Filippo Martinelli-Boneschi Flora Peyvandi Francesco Blasi Luis Téllez Albert Blanco-Grau Georg Hemmrich-Stanisak Giacomo Grasselli Giorgio Costantino Giulia Cardamone Giuseppe Foti Serena Aneli Hayato Kurihara Hesham ElAbd Ilaria My Iván Galván-Femenia Javier Martín Jeanette Erdmann Jose Ferrusquía-Acosta Koldo Garcia-Etxebarria Laura Izquierdo-Sanchez Laura R Bettini Lauro Sumoy Leonardo Terranova Leticia Moreira Luigi Santoro Luigia Scudeller Francisco Mesonero Luisa Roade Malte C Rühlemann Marco Schaefer Maria Carrabba Mar Riveiro-Barciela Maria E Figuera Basso Maria G Valsecchi María Hernandez-Tejero Marialbert Acosta-Herrera Mariella D'Angiò Marina Baldini Marina Cazzaniga Martin Schulzky Maurizio Cecconi Michael Wittig Michele Ciccarelli Miguel Rodríguez-Gandía Monica Bocciolone Monica Miozzo Nicola Montano Nicole Braun Nicoletta Sacchi Nilda Martínez Onur Özer Orazio Palmieri Paola Faverio Paoletta Preatoni Paolo Bonfanti Paolo Omodei Paolo Tentorio Pedro Castro Pedro M Rodrigues Aaron Blandino Ortiz Rafael de Cid Ricard Ferrer Roberta Gualtierotti Rosa Nieto Siegfried Goerg Salvatore Badalamenti Sara Marsal Giuseppe Matullo Serena Pelusi Simonas Juzenas Stefano Aliberti Valter Monzani Victor Moreno Tanja Wesse Tobias L Lenz Tomas Pumarola Valeria Rimoldi Silvano Bosari Wolfgang Albrecht Wolfgang Peter Manuel Romero-Gómez Mauro D'Amato Stefano Duga Jesus M Banales Johannes R Hov Trine Folseraas Luca Valenti Andre Franke Tom H Karlsen

N Engl J Med 2020 Jun 17. Epub 2020 Jun 17.

From the Institute of Clinical Molecular Biology, Christian-Albrechts-University (D.E., F.D., J.K., S. May, M. Wendorff, L.W., F.U.-W., X.Y., A.T., A. Peschuck, C.G., G.H.-S., H.E.A., M.C.R., M.E.F.B., M. Schulzky, M. Wittig, N.B., S.J., T.W., W.A., M. D'Amato, A.F.), and University Hospital Schleswig-Holstein, Campus Kiel (N.B., A.F.), Kiel, the Institute for Cardiogenetics, University of Lübeck, Lübeck (J.E.), the German Research Center for Cardiovascular Research, partner site Hamburg-Lübeck-Kiel (J.E.), the University Heart Center Lübeck (J.E.), and the Institute of Transfusion Medicine, University Hospital Schleswig-Holstein (S.G.), Lübeck, Stefan-Morsch-Stiftung, Birkenfeld (M. Schaefer, W.P.), and the Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön (O.O., T.L.L.) - all in Germany; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (D.E.); the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital-University of the Basque Country (L.B., K.G.-E., L.I.-S., P.M.R., J.M.B.), Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Clinical Biochemistry Department (A.G.C., B.N.J.), and the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute (M. D'Amato), San Sebastian, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Instituto de Salud Carlos III (L.B., M. Buti, A. Albillos, A. Palom, F.R.-F., B.M., L. Téllez, K.G.-E., L.I.-S., F.M., L.R., M.R.-B., M. Rodríguez-Gandía, P.M.R., M. Romero-Gómez, J.M.B.), the Departments of Gastroenterology (A. Albillos, B.M., L. Téllez, F.M., M. Rodríguez-Gandía), Intensive Care (R.P., A.B.O.), Respiratory Diseases (D.J., A.S., R.N.), Infectious Diseases (C.Q., E.N.), and Anesthesiology (D. Pestaña, N. Martínez), Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcalá, and Histocompatibilidad y Biologia Molecular, Centro de Transfusion de Madrid (F.G.S.), Madrid, the Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus (M. Buti, A. Palom, L.R., M.R.-B.), Hospital Clinic, University of Barcelona, and the August Pi i Sunyer Biomedical Research Institute (J.F., F.A., E.S., J.F.-A., L.M., M.H.-T., P.C.), the European Foundation for the Study of Chronic Liver Failure (J.F.), Vall d'Hebron Institut de Recerca (A. Palom, F.R.-F., A.J., S. Marsal), and the Departments of Biochemistry (A.-E.G.-F., F.R.-F., A.C.-G., C.C., A.B.-G.), Intensive Care (R.F.), and Microbiology (T.P.), University Hospital Vall d'Hebron, the Immunohematology Department, Banc de Sang i Teixits, Autonomous University of Barcelona (E.M.-D.), Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Consortium for Biomedical Research in Epidemiology and Public Health and University of Barcelona, l'Hospitalet (V. Moreno), and Autonoma University of Barcelona (T.P.), Barcelona, Universitat Autònoma de Barcelona, Bellatera (M. Buti, F.R.-F., M.R.-B.), GenomesForLife-GCAT Lab Group, Germans Trias i Pujol Research Institute (A.C.N., I.G.-F., R.C.), and High Content Genomics and Bioinformatics Unit, Germans Trias i Pujol Research Institute (L. Sumoy), Badalona, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada (J.M., M.A.-H.), the Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville (M. Romero-Gómez), and Ikerbasque, Basque Foundation for Science, Bilbao (M. D'Amato, J.M.B.) - all in Spain; the Division of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milan Bicocca (P.I., C.M.), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (D. Prati, G.B., A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, C.P., F.C., F.M.-B., F.P., F.B., G.G., G. Costantino, L. Terranova, L. Santoro, L. Scudeller, M. Carrabba, M. Baldini, M.M., N. Montano, R.G., S.P., S. Aliberti, V. Monzani, S. Bosari, L.V.), the Department of Biomedical Sciences, Humanitas University (R.A., A. Protti, A. Aghemo, A. Lleo, E.M.P., G. Cardamone, M. Cecconi, V.R., S.D.), Humanitas Clinical and Research Center, IRCCS (R.A., A. Protti, A. Aghemo, A. Lleo, A.V., C.A., E.M.P., H.K., I.M., M. Cecconi, M. Ciccarelli, M. Bocciolone, P.P., P.O., P.T., S. Badalamenti, S.D.), University of Milan (A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, F.M.-B., F.P., F.B., G.G., G. Costantino, M.M., N. Montano, R.G., S.P., S. Aliberti, S. Bosari, L.V.), and the Center of Bioinformatics, Biostatistics, and Bioimaging (M.G.V.) and the Phase 1 Research Center (M. Cazzaniga), School of Medicine and Surgery, and the Departments of Emergency, Anesthesia, and Intensive Care (G.F.), Pneumologia (P.F.), and Infectious Diseases (P.B.); University of Milano-Bicocca, Milan, the European Reference Network on Hepatological Diseases (P.I., C.M.) and the Infectious Diseases Unit (P.B.), San Gerardo Hospital, Monza, the Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo (A. Biondi, L.R.B., M. D'Angiò), the Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (A. Latiano, O.P.), the Department of Medical Sciences, Università degli Studi di Torino, Turin (S. Aneli, G.M.), and the Italian Bone Marrow Donor Registry, E.O. Ospedali Galliera, Genoa (N.S.) - all in Italy; the Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, and the Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo (M.M.G., J.R.H., T.F., T.H.K.), and the Section for Gastroenterology, Department of Transplantation Medicine, Division for Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital Rikshospitalet (J.R.H., T.F., T.H.K.), Oslo; the School of Biological Sciences, Monash University, Clayton, VIC, Australia (T.Z., M. D'Amato); Private University in the Principality of Liechtenstein (C.G.); the Institute of Biotechnology, Vilnius University, Vilnius, Lithuania (S.J.); and the Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm (M. D'Amato).

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http://dx.doi.org/10.1056/NEJMoa2020283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315890PMC
June 2020

Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes.

Cell Host Microbe 2020 Jun 29. Epub 2020 Jun 29.

ZIEL - Institute for Food & Health, Technical University of Munich, 85354 Freising, Germany; Chair of Nutrition and Immunology, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.06.004DOI Listing
June 2020

Quantitative comparison of within-sample heterogeneity scores for DNA methylation data.

Nucleic Acids Res 2020 05;48(8):e46

Big Data in BioMedicine Group, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.

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http://dx.doi.org/10.1093/nar/gkaa120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192612PMC
May 2020

Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila.

Cell Metab 2020 Apr 19;31(4):710-725.e7. Epub 2020 Mar 19.

MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2020.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156915PMC
April 2020

In Silico Guided Discovery of Novel Class I and II Epitopes Recognized by T Cells from Chagas' Disease Patients.

J Immunol 2020 Mar 14;204(6):1571-1581. Epub 2020 Feb 14.

Instituto de Investigaciones en Ingeniería Genética y Biología Molecular Dr. Héctor N. Torres, CONICET, C1428ADN Ciudad Autónoma de Buenos Aires, Argentina;

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http://dx.doi.org/10.4049/jimmunol.1900873DOI Listing
March 2020

A benchmark of hemoglobin blocking during library preparation for mRNA-Sequencing of human blood samples.

Sci Rep 2020 Mar 27;10(1):5630. Epub 2020 Mar 27.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/s41598-020-62637-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101437PMC
March 2020

VarWatch-A stand-alone software tool for variant matching.

PLoS One 2019 25;14(4):e0215618. Epub 2019 Apr 25.

Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215618PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483337PMC
February 2020

Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study.

BMC Geriatr 2020 Feb 6;20(1):45. Epub 2020 Feb 6.

Department of Neurology, Christian-Albrechts-University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1186/s12877-020-1445-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006407PMC
February 2020

Minor compositional alterations in faecal microbiota after five weeks and five months storage at room temperature on filter papers.

Sci Rep 2019 12 12;9(1):19008. Epub 2019 Dec 12.

Cancer and Inflammation Research, Department of Molecular Medicine, University of Southern Denmark, J. B. Winslows Vej 25.3, DK-5000, Odense C, Denmark.

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http://dx.doi.org/10.1038/s41598-019-55469-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908594PMC
December 2019

Normal gut microbiome in NMDA receptor encephalitis.

Neurol Neuroimmunol Neuroinflamm 2019 11 17;6(6). Epub 2019 Oct 17.

From the German Center for Neurodegenerative Diseases (DZNE) (J.H., H.P.); Department of Neurology and Experimental Neurology (J.H., C.F., J.K., H.P.), Charité - Universitätsmedizin, Berlin; and Institute of Clinical Molecular Biology (C.B., M.C.R., A.F.), Christian Albrechts University of Kiel, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857909PMC
November 2019

ZNF133 is associated with infliximab responsiveness in patients with inflammatory bowel diseases.

J Gastroenterol Hepatol 2019 Oct 1;34(10):1727-1735. Epub 2019 Apr 1.

Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/jgh.14652DOI Listing
October 2019

Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days.

J Antimicrob Chemother 2019 10;74(10):2916-2925

Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität zu Kiel, Am Botanischen Garten 1-9, Kiel, Germany.

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http://dx.doi.org/10.1093/jac/dkz297DOI Listing
October 2019

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Editorial: gut microbial profile associated with primary sclerosing cholangitis-what is new and how do we progress from here? Authors' reply.

Aliment Pharmacol Ther 2019 09;50(5):606-607

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1111/apt.15434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899696PMC
September 2019

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.

Cell 2019 09 29;178(6):1299-1312.e29. Epub 2019 Aug 29.

MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK; Institute of Structural and Molecular Biology, University College London and Birkbeck, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736778PMC
September 2019

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Authors:
Alexander Teumer Yong Li Sahar Ghasemi Bram P Prins Matthias Wuttke Tobias Hermle Ayush Giri Karsten B Sieber Chengxiang Qiu Holger Kirsten Adrienne Tin Audrey Y Chu Nisha Bansal Mary F Feitosa Lihua Wang Jin-Fang Chai Massimiliano Cocca Christian Fuchsberger Mathias Gorski Anselm Hoppmann Katrin Horn Man Li Jonathan Marten Damia Noce Teresa Nutile Sanaz Sedaghat Gardar Sveinbjornsson Bamidele O Tayo Peter J van der Most Yizhe Xu Zhi Yu Lea Gerstner Johan Ärnlöv Stephan J L Bakker Daniela Baptista Mary L Biggs Eric Boerwinkle Hermann Brenner Ralph Burkhardt Robert J Carroll Miao-Li Chee Miao-Ling Chee Mengmeng Chen Ching-Yu Cheng James P Cook Josef Coresh Tanguy Corre John Danesh Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Katalin Dittrich Jasmin Divers Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Janine F Felix Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Ron T Gansevoort Vilmantas Giedraitis Martin Gögele Franziska Grundner-Culemann Daniel F Gudbjartsson Vilmundur Gudnason Pavel Hamet Tamara B Harris Andrew A Hicks Hilma Holm Valencia Hui Xian Foo Shih-Jen Hwang M Arfan Ikram Erik Ingelsson Vincent W V Jaddoe Johanna Jakobsdottir Navya Shilpa Josyula Bettina Jung Mika Kähönen Chiea-Chuen Khor Wieland Kiess Wolfgang Koenig Antje Körner Peter Kovacs Holly Kramer Bernhard K Krämer Florian Kronenberg Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jianjun Liu Markus Loeffler Leo-Pekka Lyytikäinen Anubha Mahajan Joseph C Maranville Deborah Mascalzoni Barbara McMullen Christa Meisinger Thomas Meitinger Kozeta Miliku Dennis O Mook-Kanamori Martina Müller-Nurasyid Josyf C Mychaleckyj Matthias Nauck Kjell Nikus Boting Ning Raymond Noordam Jeffrey O' Connell Isleifur Olafsson Nicholette D Palmer Annette Peters Anna I Podgornaia Belen Ponte Tanja Poulain Peter P Pramstaller Ton J Rabelink Laura M Raffield Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Fernando Rivadeneira Heiko Runz Kathleen A Ryan Charumathi Sabanayagam Kai-Uwe Saum Ben Schöttker Christian M Shaffer Yuan Shi Albert V Smith Konstantin Strauch Michael Stumvoll Benjamin B Sun Silke Szymczak E-Shyong Tai Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Unnur Thorsteinsdottir Anke Tönjes Johanne Tremblay André G Uitterlinden Pim van der Harst Niek Verweij Suzanne Vogelezang Uwe Völker Melanie Waldenberger Chaolong Wang Otis D Wilson Charlene Wong Tien-Yin Wong Qiong Yang Masayuki Yasuda Shreeram Akilesh Murielle Bochud Carsten A Böger Olivier Devuyst Todd L Edwards Kevin Ho Andrew P Morris Afshin Parsa Sarah A Pendergrass Bruce M Psaty Jerome I Rotter Kari Stefansson James G Wilson Katalin Susztak Harold Snieder Iris M Heid Markus Scholz Adam S Butterworth Adriana M Hung Cristian Pattaro Anna Köttgen

Nat Commun 2019 09 11;10(1):4130. Epub 2019 Sep 11.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739370PMC
September 2019

Identifying Crohn's disease signal from variome analysis.

Genome Med 2019 09 30;11(1):59. Epub 2019 Sep 30.

Department of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767648PMC
September 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2019 Jul;51(7):1191-1192

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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July 2019

A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers.

Clin Epigenetics 2019 07 22;11(1):105. Epub 2019 Jul 22.

Department of Periodontology and Synoptic Dentistry, Institute for Dental and Craniofacial Sciences, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Aßmannshauser Str. 4-6, 14197, Berlin, Germany.

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http://dx.doi.org/10.1186/s13148-019-0697-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647091PMC
July 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients.

Am J Transplant 2019 05 18;19(5):1444-1451. Epub 2018 Dec 18.

Norwegian PSC Research Center, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

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http://doi.wiley.com/10.1111/ajt.15191
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May 2019

Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.

Gut 2019 05 19;68(5):854-865. Epub 2019 Jan 19.

Medical Department 1, University Hospital Dresden, Technische Universität Dresden (TU Dresden), Dresden, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-317619
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http://dx.doi.org/10.1136/gutjnl-2018-317619DOI Listing
May 2019

Rhinovirus infections change DNA methylation and mRNA expression in children with asthma.

PLoS One 2018 28;13(11):e0205275. Epub 2018 Nov 28.

University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261460PMC
April 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 03 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid.

J Autoimmun 2019 01 13;96:104-112. Epub 2018 Sep 13.

Lübeck Institute for Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany; Department of Dermatology, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.09.003DOI Listing
January 2019

Role of wnt5a in Metabolic Inflammation in Humans.

J Clin Endocrinol Metab 2018 11;103(11):4253-4264

Department of Medicine 1, University of Kiel, 24105 Kiel, Germany.

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http://dx.doi.org/10.1210/jc.2018-01007DOI Listing
November 2018

Whole-exome sequencing identifies rare genetic variations in German families with pulmonary sarcoidosis.

Hum Genet 2018 Sep 27;137(9):705-716. Epub 2018 Jul 27.

Department of Pathological Physiology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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September 2018